Preventing Early Renal Loss in Diabetes (PERL)
Resource Report
Resource Website
1+ mentions
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Preventing Early Renal Loss in Diabetes (PERL) (RRID:SCR_015862)
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PERL
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topical portal, data set, portal, disease-related portal, data or information resource, project portal
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PERL is a clinical trial for people with type 1 diabetes who have early signs of kidney problems. Its goal is to test a new way to reduce loss of kidney function using a safe and inexpensive medicine.
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kidney, type 1 diabetes, diabetes, clinical trial, medication
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is listed by: NIDDK Information Network (dkNET) is listed by: Diabetes Research Centers
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Type 1 diabetes, Diabetes, Diabetic kidney disease |
NIDDK UC4 DK101108 |
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Available to the scientific community |
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SCR_015862 |
Preventing Early Renal Loss in Diabetes |
2026-08-16 09:05:44 |
2 |
Chronic Renal Insufficiency Cohort Study
Resource Report
Resource Website
1+ mentions
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Chronic Renal Insufficiency Cohort Study (RRID:SCR_009016)
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CRIC Study, CRIC
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biomaterial supply resource, material resource
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A prospective observational national cohort study poised to make fundamental insights into the epidemiology, management, and outcomes of chronic kidney disease (CKD) in adults with intended long-term follow up. The major goals of the CRIC Study are to answer two important questions: * Why does kidney disease get worse in some people, but not in others? * Why do persons with kidney disease commonly experience heart disease and stroke? The CRIC Scientific and Data Coordinating Center at Penn receives data and provides ongoing support for a number of Ancillary Studies approved by the CRIC Cohort utilizing both data collected about CRIC study participants as well as their biological samples. The CRIC Study has enrolled over 3900 men and women with CKD from 13 recruitment sites throughout the country. Following this group of individuals over the past 10 years has contributed to the knowledge of kidney disease, its treatment, and preventing its complications. The NIDDKwill be extending the study for an additional 5 years, through 2018. An extensive set of study data is collected from CRIC Study participants. With varying frequency, data are collected in the domains of medical history, physical measures, psychometrics and behaviors, biomarkers, genomics/metabolomics, as well as renal, cardiovascular and other outcomes. Measurements include creatinine clearance and iothalamate measured glomerular filtration rate. Cardiovascular measures include blood pressure, ECG, ABI, ECHO, and EBCT. Clinical CV outcomes include MI, ischemic heart disease-related death, acute coronary syndromes, congestive heart failure, cerebrovascular disease, peripheral vascular disease, and composite outcomes. The CRIC Study has delivered in excess of 150,000 bio-samples and a dataset characterizing all 3939 CRIC participants at the time of study entry to the NIDDKnational repository. The CRIC Study will also be delivering a dataset to NCBI''''s Database for Genotypes and Phenotypes.
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clinical, epidemiology, management, outcome, adult human, medical history, physical measure, psychometrics, behavior, renal, biomarker, genomics, gwas, kidney, data sharing, bibliography, observational cohort study, male, female, cardiovascular, heart, kidney, risk factor, metabolomics
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is listed by: One Mind Biospecimen Bank Listing is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources is listed by: Diabetes Research Centers is related to: NCBI database of Genotypes and Phenotypes (dbGap) is related to: NIDDK Central Repository is related to: AASK Clinical Trial and Cohort Study has parent organization: University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA
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Chronic kidney disease, Cardiovascular disease |
NIDDK |
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Proposals to carry out ancillary studies are welcome |
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nlx_152758 |
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SCR_009016 |
Chronic Renal Insufficiency Cohort (CRIC) Study |
2026-08-15 11:29:48 |
2 |
Michigan Diabetes Research Center
Resource Report
Resource Website
1+ mentions
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Michigan Diabetes Research Center (RRID:SCR_015112)
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MDRC
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service resource, access service resource, core facility
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Multidisciplinary unit of the University of Michigan funded by the National Institute of Diabetes and Digestive and Kidney Diseases/National Institute of Health. Promotes new discoveries and enhance scientific progress through the support of basic and clinical research related to diabetes, its complications, and related disorders. Creates environment that supports innovative research; attracts and retains early stage investigators and investigators new to diabetes research; provides core services that leverage funding and unique expertise; fosters interdisciplinary collaborations; raises awareness and interest in fundamental and clinical diabetes research at their institutions, as well as locally, regionally, and nationally.
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clinical diabetes research, multidisciplinary research, endocrine and metabolic disorders,
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is listed by: NIDDK Information Network (dkNET) has organization facet: Michigan Diabetes Research Center Administrative Core Facility has organization facet: Michigan Diabetes Research Center Clinical Core Facility has organization facet: Michigan Diabetes Research Center Microscopy and Image Analysis Core Facility has organization facet: Michigan Diabetes Research Center Molecular Genetics Core Facility has organization facet: Michigan Diabetes Research Center Animal Studies Core is organization facet of: Diabetes Research Centers
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Diabetes |
NIDDK P30DK020572 |
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Restricted |
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http://diabetesresearch.med.umich.edu |
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SCR_015112 |
Michigan Diabetes Research Center (MDRC) |
2026-08-15 11:25:13 |
4 |
Drug-Induced Liver Injury Network
Resource Report
Resource Website
1+ mentions
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Drug-Induced Liver Injury Network (RRID:SCR_001524)
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DILIN
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biomaterial supply resource, material resource
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Prospective and retrospective registry of well-characterized cases of drug-induced liver disease. The goals of Network include the development of standardized procedures to identify and fully characterize bona fide cases of drug- and complementary and alternative medicines (CAM)-induced liver injury, and to conduct controlled, clinical studies that will include extensive collection of data, serum, DNA, and tissue specimens. Cases of liver injury due to herbal medications are also included. The network will also develop terminology and standardized definitions for DILI, and to develop causality assessment instruments that are sensitive, specific, and reproducible. DILIN is funded by a cooperative agreement and includes five clinical centers and a central data coordinating center. The research goals of DILIN are to: * Create a registry of carefully documented DILI cases * Identify clinical, immunological, and environmental risk factors for drug- and CAM-mediated hepatotoxicity * Create a bank of biological specimens consisting of DNA, plasma, and immortalized lymphocytes to facilitate detailed genetic analyses * Characterize the natural history of drug- and CAM-induced DILI for at least six months following enrollment * Develop the capability to recontact these individuals over an extended period of time so that additional studies exploring DILI mechanisms can be performed Two studies are being initiated by the network. In the Retrospective Study, the implicated drugs are restricted to isoniazid, phenytoin, combination clavulanic acid/amoxicillin, and valproic acid (Depakote), Nitrofurantoin, Trimethoprim-sulfamethoxazole, Minocycline, and Quinolone antibiotics. These drugs were chosen because they are frequently administered to patients not receiving other hepatotoxic drugs, making it easier to establish causality. Patients must be alive, and the date of onset of the DILI episode must be on or after January 1, 1994. In the Prospective Study, all incident cases of drug- and CAM-induced liver injury are being considered. Initial presentation to a healthcare professional must be within the previous six months. A detailed medication history of the implicated DILI drug together with all prescription, OTC, and herbal medications is being recorded. Liver and serological tests are being performed to characterize the injury and to exclude competing causes of liver injury. A blood sample is also being drawn for plasma storage and DNA isolation. These cases will be followed longitudinally to characterize the long-term effects of the DILI episode. For both studies, documented, clinically significant DILI must be recorded in the patient's medical charts so that a causal determination can be made. Patients will be excluded if they are unwilling or unable to provide a blood sample or participate in the genetics component. Children under two years of age at the time of enrollment are excluded due to blood-volume requirements. If you have patients who are eligible to participate in either study, please contact one the DILIN clinical sites. As a general policy, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invites investigator-initiated research project applications for ancillary studies to ongoing, large-scale clinical trials, epidemiological studies, and disease databases supported by the Institute. These studies are focused on a wide range of diseases and conditions including diabetes, obesity, acute and chronic liver disease, chronic kidney disease, and benign prostatic hyperplasia, among others.
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prescription drug, over-the-counter drug, alternative medicine, herbal product, supplement, serum, dna, tissue, blood, immortalized lymphocyte, drug, medication, quinolone antibiotic, isoniazid, phenytoin, clavulanic acid, amoxicillin, valproic acid, depakote, nitrofurantoin, trimethoprim-sulfamethoxazole, minocycline, diagnosis, hepatotoxicity, risk factor, genetic analysis
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is listed by: One Mind Biospecimen Bank Listing is listed by: NIDDK Information Network (dkNET) is listed by: Diabetes Research Centers has parent organization: Duke University; North Carolina; USA
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Liver injury, Hepatic injury, Drug-induced liver disease |
NIDDK |
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Qualified investigators, Account required |
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nlx_152822 |
https://dilin.dcri.duke.edu/ |
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SCR_001524 |
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2026-08-15 11:29:37 |
6 |
Nutrition and Obesity Research Centers
Resource Report
Resource Website
10+ mentions
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Nutrition and Obesity Research Centers (RRID:SCR_004131)
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NORC
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topical portal, portal, organization portal, disease-related portal, resource, data or information resource
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Portal to research centers and core facilities specifically support obesity research and better understand the relationship between health and nutrition.
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obesity core facility, obesity portal, obesity research center
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is listed by: NIDDK Information Network (dkNET) is listed by: Diabetes Research Centers is affiliated with: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases has organization facet: Boston Nutrition and Obesity Research Centers has organization facet: Nutrition and Obesity Research Centers at Harvard has organization facet: Mid-Atlantic Nutrition Obesity Research Center has organization facet: New York Obesity Nutrition Research Center has organization facet: Pennington Biomedical Research Center Nutrition and Obesity Research Center has organization facet: University of Alabama at Birmingham Nutrition and Obesity Research Center has organization facet: University of California San Francisco Nutrition and Obesity Research Center has organization facet: University of Colorado Anschutz Medical Campus Nutrition and Obesity Research Center has organization facet: University of Michigan Nutrition and Obesity Research Center has organization facet: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center has organization facet: University of Washington Nutrition and Obesity Research Center has organization facet: Washington University St. Louis Nutrition Obesity Research Center
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Obesity, Nutrition-related disease, Eating disorder, Anorexia nervosa, AIDS, Cancer |
NIDDK RFA-DK16-006 |
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Available to the research community |
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nlx_158684 |
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SCR_004131 |
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2026-08-16 09:03:53 |
46 |
Johns Hopkins University; Maryland; USA
Resource Report
Resource Website
10+ mentions
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Johns Hopkins University; Maryland; USA (RRID:SCR_010247)
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JHU
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university
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Johns Hopkins University is private research university in Baltimore, Maryland. Founded in 1876, university was named for its first benefactor, American entrepreneur, abolitionist, and philanthropist Johns Hopkins.
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private, university, Baltimore, Maryland
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uses: DIRECT2experts is affiliated with: Diabetes Research Centers is related to: Alzheimers Disease Genetics Consortium is related to: International AMD Genetics Consortium is related to: ABX Guide is related to: Clinical and Translational Science Awards Consortium is parent organization of: SynaptomeDB is parent organization of: Johns Hopkins University School of Medicine; Baltimore, Maryland; USA is parent organization of: sim4cc is parent organization of: MRI Studio is parent organization of: CKID A Prospective Cohort Study of Kidney Disease in Children is parent organization of: Nonalcoholic Steatohepatitis Clinical Research Network is parent organization of: ASprofile is parent organization of: GlimmerHMM is parent organization of: Neurogenetics and Behavior Center is parent organization of: Human Proteinpedia is parent organization of: Schramm Lab Spinal Cord Atlases is parent organization of: NetPath is parent organization of: Academic Drug Discovery Consortium is parent organization of: CardioVascular Research Grid (CVRG) is parent organization of: Johns Hopkins University; Undergraduate Neuroscience Program is parent organization of: Bowtie is parent organization of: FLASH is parent organization of: TMAJ is parent organization of: Gastroparesis Clinical Research Consortium is parent organization of: HPRD - Human Protein Reference Database is parent organization of: Atlweb: Alternatives to Animal Testing is parent organization of: Center for Inherited Disease Research is parent organization of: The Protein Coil Library is parent organization of: HIV Guide is parent organization of: Johns Hopkins School of Medicine Department of Molecular and Comparative Pathobiology is parent organization of: Classic Articles in Visual Perception is parent organization of: Experimental Man Blog is parent organization of: MYC Cancer Gene is parent organization of: JIST: Java Image Science Toolkit is parent organization of: DOTS WM tract segmentation is parent organization of: JHU Proj. in Applied Medical Imaging is parent organization of: LDDMM is parent organization of: Johns Hopkins Bloomberg School of Public Health; Maryland; USA is parent organization of: Genetic Resources Core Facility is parent organization of: LS-SNP/PDB is parent organization of: JHU Deep Sequencing and Microarray Core is parent organization of: Glimmer is parent organization of: Johns Hopkins University Labs and Facilities is parent organization of: CRAVAT is parent organization of: John Hopkins University, In-Vivo Cellular Molecular Imaging Center is parent organization of: RosettaDock is parent organization of: CoGAPS is parent organization of: Blox is parent organization of: National Resource for Quantitative Functional MRI is parent organization of: Myrna is parent organization of: CAWorks is parent organization of: Principal Components Analysis of Scalar, Vector, and Mesh Vertex Data is parent organization of: Longitudinal MS Lesion Imaging Archive is parent organization of: Image Synthesis Tools is parent organization of: Atlases of amygdala and hippocampus for pediatric populations is parent organization of: HISAT2 is parent organization of: neurodata is parent organization of: Johns Hopkins University Integrated Imaging Center Core Facility is parent organization of: Center for Computational Biology at JHU is parent organization of: TopHat is parent organization of: PyRosetta is parent organization of: Ecosystem for Multi-modal Brain-behavior Experimentation and Research is parent organization of: Brain Observatory Storage Service and Database (BossDB) is parent organization of: Johns Hopkins University School of Medicine Genetic Resources Core Facility
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nlx_97251, , Wikidata: Q193727, GRID: grid.21107.35, ISNI: 0000 0001 2171 931, Crossref Funder ID: 100007880 |
https://ror.org/00za53h95 |
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SCR_010247 |
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2026-08-15 11:24:02 |
21 |