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URL: http://toppgene.cchmc.org/
Proper Citation: ToppGene Suite (RRID:SCR_005726)
Description: ToppGene Suite is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network. ToppGene Suite is a one-stop portal for (i) gene list functional enrichment, (ii) candidate gene prioritization using either functional annotations or network analysis and (iii) identification and prioritization of novel disease candidate genes in the interactome. Functional annotation-based disease candidate gene prioritization uses a fuzzy-based similarity measure to compute the similarity between any two genes based on semantic annotations. The similarity scores from individual features are combined into an overall score using statistical meta-analysis.
Synonyms: ToppGene
Resource Type: resource, data or information resource, portal, service resource, data analysis service, analysis service resource, database, production service resource
Defining Citation: PMID:19465376
Keywords: gene portal, enrichment analysis, functional annotation, gene prioritization, protein interaction, bio.tools, FASEB list
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The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant 2U24DK097771-09.
Email: info_at_ dknet.org
