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Tutorial Listing

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Evidence for physiological processes in which my gene of interest is involved [1 Use Case]
  • Mouse phenotypic evidence for physiological processes regulated by Agap2 

    This tutorial can assist you in finding mammalian phenotypes that are associated with Agap2 KO manipulations in mouse models. The MMPC is a National Institutes of Health-Sponsored resource that provides experimental testing services to scientists studying diabetes, obesity, diabetic complications, and other metabolic diseases in mice.

    Resources Used:   National Mouse Metabolic Phenotyping Centers (RRID:SCR_008997); 



Evidence for genes involved in my physiological process of interest [1 Use Case]
  • Mouse phenotypic evidence for genes involved in regulation of body weight 

    This tutorial can assist you in finding experimental datasets are relevant to increased body weight in mouse. The MMPC is a National Institutes of Health-Sponsored resource that provides experimental testing services to scientists studying diabetes, obesity, diabetic complications, and other metabolic diseases in mice.

    Resources Used:   National Mouse Metabolic Phenotyping Centers (RRID:SCR_008997); 



Evidence for genes & signaling pathways that involved in my physiological events [2 Use Cases]
  • Mouse phenotypic evidence for genes involved in regulation of glucose metabolism & transcriptomic evidence for their regulation by catalytic receptors 

    This tutorial can assist you in finding evidence for gene sets and signaling pathways that are involved in regulation of glucose tolerance.

    dkNET Hypothesis Center creates an integrator tool that brings the Signaling Pathways Project (SPP) and The Mouse Metabolic Phenotyping Centers (MMPC) together to connect cellular signaling pathways and gene expression with physiological phenotypes. This one-of-a-kind tool makes it easier for researchers to find gene sets and signaling pathways relevant to mouse and human phenotypes for generating hypotheses.

    Resources Used:   Signaling Pathways Project (RRID:SCR_018412);  National Mouse Metabolic Phenotyping Centers (RRID:SCR_008997); 




  • Mouse phenotypic evidence for genes involved in regulation of insulin levels & ChIP-Seq evidence for their regulation by histone acetyltranserases 

    This tutorial can assist you in finding evidence for gene sets and signaling pathways that are involved in regulating circulating insulin level.

    dkNET Hypothesis Center creates an integrator tool that brings the Signaling Pathways Project (SPP) and The Mouse Metabolic Phenotyping Centers (MMPC) together to connect cellular signaling pathways and gene expression with physiological phenotypes. This one-of-a-kind tool makes it easier for researchers to find gene sets and signaling pathways relevant to mouse and human phenotypes for generating hypotheses.

    Resources Used:   Signaling Pathways Project (RRID:SCR_018412);  National Mouse Metabolic Phenotyping Centers (RRID:SCR_008997);