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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PhenoGO
 
Resource Report
Resource Website
1+ mentions
PhenoGO (RRID:SCR_013646) data or information resource, database PhenoGO is a computed database designed for high throughput mining that provides phenotypic and experimental context - such as the cell type, disease, tissue, and organ - to existing annotations between gene products and Gene Ontology (GO) terms, as specified in the Gene Ontology Annotations (GOA) for multiple model organisms. Phenotypic and Experimental (P&E) contexts to identifiers are computationally mapped to general biological ontologies, including: the Cell Ontology (CO), phenotypes from the Unified Medical Language System (UMLS), species from Taxonomy of the National Center for Biotechnology Information (NCBI) taxonomy, and specialized ontologies such as Mammalian Phenotype Ontology (MP) and Mouse Anatomy (MA). uses: WormBase
uses: SGD
uses: Gene Ontology
uses: Mouse Genome Informatics (MGI)
uses: FlyBase
is related to: WormBase
is related to: SGD
is related to: Gene Ontology
is related to: Mouse Genome Informatics (MGI)
is related to: FlyBase
has parent organization: University of Arizona; Arizona; USA
Available to the research community, Acknowledgement requested nlx_152722 www.phenogo.org SCR_013646 Phenotype Context Database for Gene Ontology Annotations 2026-09-03 05:03:38 2
dcGO
 
Resource Report
Resource Website
10+ mentions
dcGO (RRID:SCR_014392) data or information resource, database A database of domain-centric ontologies on functions, phenotypes, diseases and more. As a biomedical ontology resource, dcGO integrates functional, phenotypic, disease, and drug information. As a protein domain resource, it includes annotations to both the individual domains and supra-domains. Domain classifications and ontologies are organized in hierarchies, and dcGO includes the facility to browse the hierarchies: SCOP Hierarchy for browsing domains, GO Hierarchy for browsing GO terms, and BO Hierarchy for browsing other terms (mostly phenotypes). Users can mine and browse through resources. database, mining, domain centric ontology, phenotype, human disease, drug, biomedical ontology, protein domain, hierarchy uses: Gene Ontology
has parent organization: University of Bristol; Bristol; United Kingdom
PMID:23161684 Acknowledgement required, Both flat files and MySQL tables are available for download SCR_014392 2026-09-03 05:03:40 27
OncoboxPD
 
Resource Report
Resource Website
1+ mentions
OncoboxPD (RRID:SCR_023723) data or information resource, database Structured curated collection of protein based and of metabolic human molecular pathways. Human molecular pathways database with tools for activity calculating and visualization.All pathways are functionally classified according to GO terms enrichment patterns. All pathway participants, their interactions and reactions are uniformly processed and annotated, and are ready for numeric analysis of experimental expression data.For every comparison graph is generated summarizing top up and down regulated pathways. Gene Ontology terms enrichment patterns, human molecular pathways, curated collection, GO terms enrichment patterns, experimental expression data analysis, is related to: oncoboxlib
is related to: Gene Ontology
National Natural Science Foundation of China ;
Qingdao Key Health Discipline Development Fund ;
Qingdao Key Research Project ;
Russian Science Foundation
PMID:35615022 Free, Freely available SCR_023723 Oncobox Pathway Databank 2026-09-03 05:04:08 8
Blast2GO
 
Resource Report
Resource Website
5000+ mentions
Blast2GO (RRID:SCR_005828) B2G software application, software resource An ALL in ONE tool for functional annotation of (novel) sequences and the analysis of annotation data. Blast2GO (B2G) joins in one universal application similarity search based GO annotation and functional analysis. B2G offers the possibility of direct statistical analysis on gene function information and visualization of relevant functional features on a highlighted GO direct acyclic graph (DAG). Furthermore B2G includes various statistics charts summarizing the results obtained at BLASTing, GO-mapping, annotation and enrichment analysis (Fisher''''s Exact Test). All analysis process steps are configurable and data import and export are supported at any stage. The application also accepts pre-existing BLAST or annotation files and takes them to subsequent steps. The tool offers a very suitable platform for high throughput functional genomics research in non-model species. B2G is a species-independent, intuitive and interactive desktop application which allows monitoring and comprehending the whole annotation and analysis process supported by additional features like GO Slim integration, evidence code (EC) consideration, a Batch-Mode or GO-Multilevel-Pies. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible annotation, visualization, analysis, functional genomics, editor, statistical analysis, slimmer-type tool, ontology or annotation editor, functional analysis, direct acyclic graph, analysis, high throughput, functional genomics is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
has parent organization: Principe Felipe Research Centre; Valencia; Spain
MCyT GEN 2001 - 4885-C05-03;
eTumour Project FP6-2002-LIFESCIHEALTH 503094
PMID:16081474 Free for academic use OMICS_01475, nlx_149335 SCR_005828 Blast2GO (B2G) 2026-09-03 05:05:07 8620
FSST - Functional Similarity Search Tool
 
Resource Report
Resource Website
FSST - Functional Similarity Search Tool (RRID:SCR_005819) FSST software application, software resource The Functional Similarity Search Tool (FSST) has been implemented for comparing user defined sets of annotated entities. FSST supports the computation of functional similarity scores based on an individual ontology and of combined scores. Its multi-threaded Java implementation takes advantage of symmetric multi-processing computers, decreasing runtime considerably. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible other analysis, functional similarity search, annotation, ontology, java, training tools is listed by: 3DVC
is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: GOTaxExplorer
has parent organization: Max-Planck-Institute for Informatics; Saarbrucken; Germany
BMBF 016R0453;
DFG KFO 129/1-1;
European Union F6 contract LSHG-CT-2003-503265
PMID:17346342 Free for academic use nlx_149320 SCR_005819 Functional Similarity Search Tool (FSST), Functional Similarity Search Tool 2026-09-03 05:03:45 0
Bioconductor
 
Resource Report
Resource Website
10000+ mentions
Bioconductor (RRID:SCR_006442) software repository, software resource, software toolkit Software repository for R packages related to analysis and comprehension of high throughput genomic data. Uses separate set of commands for installation of packages. Software project based on R programming language that provides tools for analysis and comprehension of high throughput genomic data. catalog, analysis, genomic, metadata, comprehension, statistical, data lists: MSstats
lists: MetaCyto
lists: MetaNeighbor
lists: tximport
lists: clusterProfiler
lists: ropls
lists: FlowSOM
lists: scran
lists: Rsubread
lists: riboSeqR
lists: Biostrings
lists: ConsensusClusterPlus
lists: DESeq2
lists: GenomicFeatures
lists: affy
lists: affydata
lists: Genomic Ranges
lists: Goseq
lists: GAGE
lists: CATALYST
lists: Scmap
lists: Scfind
lists: GenomicRanges
lists: org.Rn.eg.db
lists: Extending Guilt by Association by Degree
lists: ggtree
lists: StructuralVariantAnnotation
lists: scTHI
lists: EnhancedVolcano
lists: DEGreport
lists: variancePartition
lists: biomaRt
lists: MSnbase
lists: ReactomePA
lists: SynergyFinder
lists: CiteFuse
lists: fgsea
lists: GSVA
lists: SimFFPE
lists: FilterFFPE
lists: PhenStat
lists: ChIPseeker
lists: AUCell
lists: svaNUMT
lists: KEGGgraph
lists: epialleleR
lists: microbiome
lists: Orthology.eg.db
lists: org.Hs.eg.db
lists: ExperimentHub
lists: combi
is listed by: OMICtools
is listed by: Gene Ontology Tools
is listed by: SoftCite
is affiliated with: RnaSeqGeneEdgeRQL
is related to: asSeq
is related to: Gene Ontology
is related to: CRCView
is related to: R Project for Statistical Computing
is related to: GEO2R
is related to: LIMMA
is related to: VisR
is related to: edgeR
is related to: IMEx - The International Molecular Exchange Consortium
is related to: CATALYSTLite
is related to: ascend
is related to: minet
has parent organization: Fred Hutchinson Cancer Center
is parent organization of: ncdfFlow
is parent organization of: GenomicRanges
is parent organization of: ReadqPCR
is parent organization of: flowCL
is parent organization of: flowBin
is parent organization of: CorMut
is parent organization of: metaSeq
is parent organization of: VariantAnnotation
is parent organization of: ReQON
is parent organization of: timecourse
is parent organization of: RmiR.Hs.miRNA
is parent organization of: AffyRNADegradation
is parent organization of: ArrayExpress (R)
is parent organization of: GEOquery
is parent organization of: MIMOSA
is parent organization of: HEM
is parent organization of: CNTools
is parent organization of: cn.FARMS
is parent organization of: Clonality
is parent organization of: TransView
is parent organization of: pvac
is parent organization of: QUALIFIER
is parent organization of: flowStats
is parent organization of: rTANDEM
is parent organization of: flowFlowJo
is parent organization of: iASeq
is parent organization of: OLINgui
is parent organization of: SigFuge
is parent organization of: Rdisop
is parent organization of: GeneExpressionSignature
is parent organization of: iBMQ
is parent organization of: TDARACNE
is parent organization of: flowQ
is parent organization of: FlipFlop
is parent organization of: RmiR
is parent organization of: bsseq
is parent organization of: ExomePeak
is parent organization of: flowWorkspace
is parent organization of: massiR
is parent organization of: rbsurv
is parent organization of: GeneMeta
is parent organization of: MergeMaid
is parent organization of: categoryCompare
is parent organization of: metahdep
is parent organization of: snpStats: SnpMatrix and XSnpMatrix classes and methods
is parent organization of: CNVtools
is parent organization of: CGEN
is parent organization of: RCASPAR
is parent organization of: iterativeBMAsurv
is parent organization of: multtest
is parent organization of: globaltest
is parent organization of: MinimumDistance
is parent organization of: VegaMC
is parent organization of: VanillaICE
is parent organization of: SNPchip
is parent organization of: SMAP
is parent organization of: quantsmooth
is parent organization of: mBPCR
is parent organization of: ITALICS
is parent organization of: GenoSet
is parent organization of: exomeCopy
is parent organization of: CGHregions
is parent organization of: CGHbase
is parent organization of: beadarraySNP
is parent organization of: GLAD
is parent organization of: methylMnM
is parent organization of: methyAnalysis
is parent organization of: ARRmNormalization
is parent organization of: ChIPsim
is parent organization of: yaqcaffy
is parent organization of: wateRmelon
is parent organization of: sRAP
is parent organization of: spotSegmentation
is parent organization of: SNM
is parent organization of: SNAGEE
is parent organization of: Simpleaffy
is parent organization of: qcmetrics
is parent organization of: MANOR
is parent organization of: limmaGUI
is parent organization of: ffpe
is parent organization of: dyebias
is parent organization of: DEXUS
is parent organization of: BeadDataPackR
is parent organization of: aroma.light
is parent organization of: ArrayTools
is parent organization of: beadarray
is parent organization of: arrayQuality
is parent organization of: arrayMvout
is parent organization of: affyQCReport
is parent organization of: affyPLM
is parent organization of: AffyExpress
is parent organization of: waveTiling
is parent organization of: gprege
is parent organization of: oneChannelGUI
is parent organization of: LMGene
is parent organization of: factDesign
is parent organization of: pickgene
is parent organization of: betr
is parent organization of: SCAN.UPC
is parent organization of: arrayQualityMetrics
is parent organization of: CALIB
is parent organization of: DEDS
is parent organization of: Harshlight
is parent organization of: MiChip
is parent organization of: OCplus
is parent organization of: bridge
is parent organization of: fRMA
is parent organization of: genArise
is parent organization of: lapmix
is parent organization of: maCorrPlot
is parent organization of: maSigPro
is parent organization of: MACAT
is parent organization of: maigesPack
is parent organization of: MDQC
is parent organization of: metaArray
is parent organization of: nnNorm
is parent organization of: plgem
is parent organization of: PVCA
is parent organization of: RAMA
is parent organization of: stepNorm
is parent organization of: virtualArray
is parent organization of: LPE
is parent organization of: vsn
is parent organization of: ACME
is parent organization of: CoGAPS
is parent organization of: flowFP
is parent organization of: rMAT
is parent organization of: SLqPCR
is parent organization of: nondetects
is parent organization of: unifiedWMWqPCR
is parent organization of: sSeq
is parent organization of: CNVrd2
is parent organization of: plateCore
is parent organization of: RSVSim
is parent organization of: TCC
is parent organization of: CQN
is parent organization of: COMPASS
is parent organization of: flowClust
is parent organization of: SPADE
is parent organization of: OrderedList
is parent organization of: SamSPECTRAL
is parent organization of: flowUtils
is parent organization of: RchyOptimyx
is parent organization of: TEQC
is parent organization of: flowType
is parent organization of: ADaCGH2
is parent organization of: flowViz
is parent organization of: flowTrans
is parent organization of: flowQB
is parent organization of: shinyTANDEM
is parent organization of: flowPlots
is parent organization of: flowPhyto
is parent organization of: flowCore
is parent organization of: flowMerge
is parent organization of: flowMap
is parent organization of: flowMeans
is parent organization of: spliceR
is parent organization of: flowMatch
is parent organization of: flowFit
is parent organization of: flowCyBar
is parent organization of: BEAT
is parent organization of: flowBeads
is parent organization of: CAMERA - Collection of annotation related methods for mass spectrometry data
is parent organization of: MBASED
is parent organization of: MethylAid
is parent organization of: sapFinder
is parent organization of: Pathview
is parent organization of: DSS
is parent organization of: RMassBank
is parent organization of: iontree
is parent organization of: Basic4Cseq
is parent organization of: BiGGR
is parent organization of: mzR
is parent organization of: PAPi
is parent organization of: CGHnormaliter
is parent organization of: Chimera
is parent organization of: BRAIN
is parent organization of: tweeDEseq
is parent organization of: SurvComp
is parent organization of: Triplex
is parent organization of: OmicCircos
is parent organization of: ggbio
is parent organization of: HTqPCR
is parent organization of: NormqPCR
is parent organization of: ddCt
is parent organization of: EasyqpcR
is parent organization of: SWAN
is parent organization of: PING
is parent organization of: DMRforPairs
is parent organization of: SeqGSEA
is parent organization of: h5vc
is parent organization of: deepSNV
is parent organization of: RUVSeq
is parent organization of: BHC
is parent organization of: epigenomix
is parent organization of: IRanges
is parent organization of: GeneNetworkBuilder
is parent organization of: MethylSeekR
is parent organization of: SRAdb
is parent organization of: casper
is parent organization of: htSeqTools
is parent organization of: ChIPXpress
is parent organization of: methVisual
is parent organization of: DeconRNASeq
is parent organization of: EDASeq
is parent organization of: RIPSeeker
is parent organization of: ShortRead
is parent organization of: seqbias
is parent organization of: DEGseq
is parent organization of: arrayMagic
is parent organization of: easyRNASeq
is parent organization of: DNAcopy
is parent organization of: CRLMM
is parent organization of: motifRG
is parent organization of: MMDiff
is parent organization of: MiRaGE
is parent organization of: LVSmiRNA
is parent organization of: ExiMiR
is parent organization of: RPA
is parent organization of: CexoR
is parent organization of: lumi
is parent organization of: baySeq
is parent organization of: tRanslatome
is parent organization of: DNaseR
is parent organization of: DEXSeq
is parent organization of: ChIPpeakAnno
is parent organization of: inSilicoMerging
is parent organization of: minfi
is parent organization of: Methylumi
is parent organization of: miRNApath
is parent organization of: sva package
is parent organization of: dmrFinder
is parent organization of: rqubic
is parent organization of: BicARE
is parent organization of: iBBiG
is parent organization of: eisa
is parent organization of: ChAMP
is parent organization of: cghMCR
is parent organization of: Bioconductor mailing list
is parent organization of: DiffBind
is parent organization of: NarrowPeaks
is parent organization of: CSAR
is parent organization of: CSSP
is parent organization of: TargetScore
is parent organization of: snapCGH
is parent organization of: iChip
is parent organization of: TurboNorm
is parent organization of: Ringo
is parent organization of: RLMM
is parent organization of: charm
is parent organization of: BiSeq
is parent organization of: MEDME
is parent organization of: MEDIPS
is parent organization of: BayesPeak
is parent organization of: ChIPseqR
is parent organization of: Rolexa
is parent organization of: cn.mops
is parent organization of: RankProd
is parent organization of: phyloseq
is parent organization of: HiTC
is parent organization of: CancerMutationAnalysis
is parent organization of: aCGH
is parent organization of: Repitools
is parent organization of: flowPeaks
is parent organization of: Mfuzz
is parent organization of: les
is parent organization of: OLIN
is parent organization of: affylmGUI
is parent organization of: CYCLE
is parent organization of: r3Cseq
is parent organization of: Piano
is parent organization of: RamiGO
hosts: DESeq
hosts: rGADEM
hosts: PICS
hosts: Jmosaics
hosts: R453Plus1Toolbox
hosts: BAC
hosts: targetscan.Hs.eg.db
hosts: Starr
hosts: Qvalue
hosts: topGO
hosts: MmPalateMiRNA
hosts: CGHcall
hosts: EGSEA
hosts: NOISeq
Catt Family Foundation ;
Dana Farber Cancer Institute ;
NHGRI R33 HG002708
PMID:15461798 Free, Freely available OMICS_01759, nif-0000-10445 SCR_006442 2026-09-03 05:05:09 24163
Gene Ontology Browsing Utility (GOBU)
 
Resource Report
Resource Website
Gene Ontology Browsing Utility (GOBU) (RRID:SCR_005662) GOBU software resource, source code Gene Ontology Browsing Utility (GOBU) (GOBU) is a Java-based software program for integrating biological annotation catalogs under an extendable software architecture. Users may interact with the Gene Ontology and user-defined hierarchy data of genes, and then use its plugins to (and not limited to) (1) browse the GO hierarchy with user defined data, (2) browse GO-oriented expression levels in the user data, (3) compute GO enrichment, and/or (4) customize data reporting. A set of classes and utility functions has been established so that a customized program can be made as a plugin or a command-line tool that programmically manipulate the Gene Ontology and specified user data. See the source code repository for examples. Reference Lin WD, Chen YC, Ho JM, Hsiao CD. GOBU: Toward an Integration Interface for Biological Objects. Journal of Information Science and Engineering. 2006 22(1):19-29. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible annotation, gene, browser, computation, visualization, software library, statistical analysis, term enrichment, ontology or annotation browser, ontology or annotation visualization is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Academia Sinica; Taipei; Taiwan
Open unspecified license - Free for academic use nlx_149098 SCR_005662 Gene Ontology Browsing Utility 2026-09-03 05:06:27 0
Honey Bee Brain EST Project
 
Resource Report
Resource Website
1+ mentions
Honey Bee Brain EST Project (RRID:SCR_002389) Bee-ESTdb biomaterial supply resource, material resource A database integrating data from the bee brain EST sequencing project with data from sequencing and gene research projects from other organisms, primarily the fruit fly Drosophila melanogaster. The goal of Bee-ESTdb is to provide updated information on the genes of the honey bee, currently using annotation primarily from flies to suggest cellular roles, biological functions, and evolutionary relationships. The site allows searches by sequence ID, EST annotations, Gene Ontology terms, Contig ID and using BLAST. Very nice resource for those interested in comparative genomics of brain. A normalized unidirectional cDNA library was made in the laboratory of Prof. Bento Soares, University of Iowa. The library was subsequently subtracted. Over 20,000 cDNA clones were partially sequenced from the normalized and subtracted libraries at the Keck Center, resulting in 15,311 vector-trimmed, high-quality, sequences with an average read length of 494 bp. and average base-quality of 41. These sequences were assembled into 8966 putatively unique sequences, which were tested for similarity to sequences in the public databases with a variety of BLAST searches. The Clemson University Genomics Institute is the distributor of these public domain cDNA clones. For information on how to purchase an individual clone or the entire collection, please contact www.genome.clemson.edu/orders/ or generobi (at) life.uiuc.edu. expressed sequence tag, brain, behavior, cdna, blast, gene, annotation, microarray, gene expression, comparative genomics, cdna clone, resource:genbank is listed by: One Mind Biospecimen Bank Listing
is related to: One Mind Biospecimen Bank Listing
is related to: Gene Ontology
has parent organization: University of Illinois at Urbana-Champaign; Illinois; USA
NSF ;
University of Illinois Critical Research Initiatives Program ;
Burroughs Wellcome Fund
PMID:11932240 Free nif-0000-00118 SCR_002389 Honeybee EST Project 2026-09-03 05:03:32 5
Gemma
 
Resource Report
Resource Website
1000+ mentions
Gemma (RRID:SCR_008007) Gemma data or information resource, database Resource for reuse, sharing and meta-analysis of expression profiling data. Database and set of tools for meta analysis, reuse and sharing of genomics data. Targeted at analysis of gene expression profiles. Users can search, access and visualize coexpression and differential expression results. chip, microarray, functional genomics, gene expression, coexpression, differential expression, FASEB list is used by: NIF Data Federation
is used by: Integrated Data Annotation
is listed by: Debian
is listed by: SoftCite
is related to: Gene Ontology
is related to: Gene Expression Omnibus
is related to: Phenocarta
has parent organization: University of British Columbia; British Columbia; Canada
is parent organization of: Neurocarta
Canadian Foundation for Innovation ;
Canadian Institutes for Health Research ;
Michael Smith Foundation for Health Research ;
NIGMS GM076990
PMID:22782548 Free, Freely available nif-0000-08127, r3d100012747 https://sources.debian.org/src/gemma/, https://doi.org/10.17616/R36R54, https://doi.org/10.17616/R36R54 SCR_008007 2026-09-03 05:02:38 1145
GOstat
 
Resource Report
Resource Website
100+ mentions
GOstat (RRID:SCR_008535) GOstat analysis service resource, data analysis service, production service resource, service resource GOstat is a tool that allows you to find statistically overrepresented Gene Ontologies within a group of genes. The Gene-Ontology database (GO: http://www.geneontology.org) provides a useful tool to annotate and analyze the function of large numbers of genes. Modern experimental techniques, as e.g. DNA microarrays, often result in long lists of genes. To learn about the biology in this kind of data it is desirable to find functional annotation or Gene-Ontology groups which are highly represented in the data. This program (GOstat) should help in the analysis of such lists and will provide statistics about the GO terms contained in the data and sort the GO annotations giving the most representative GO terms first. Run GOstat: * Go to search form - Computes GO statistics of a list of genes selected from a microarray. * GOstat Display - You can store results from a previously run and view them here, either by uploading them as a file or putting them on a selected URL. * Upload Custom GO Annotations - This allows you to upload your own GO annotation database and use it with GOstat. Variants of GOstat: * Rank GOstat - Takes input from all genes on microarray instead of using a fixed cutoff and uses ranks using a Wilcoxon test or either ranks or pvalues to score GOs using Kolmogorov-Smirnov statistics. * Gene Abundance GOstats - Takes input from all genes on microarray and sums up the gene abundances for each GO to compute statistics. * Two list GOstat - Compares GO statistics in two independent lists of genes, not necessarily one of them being the complete list the other list is sampled from. Platform: Online tool, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, gene ontology, annotation, statistical analysis, FASEB list is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Walter and Eliza Hall Institute of Medical Research; Victoria; Australia
DFG PMID:14962934 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30625 SCR_008535 2026-09-03 05:02:49 159
SeqExpress
 
Resource Report
Resource Website
SeqExpress (RRID:SCR_007075) data processing software, software application, software resource A comprehensive analysis and visualization software package for gene expression experiments that provides: a number of clustering and analysis techniques; integrated gene expression and analysis result visualizations, integration with the Gene Expression Omnibus; and an optional data sharing architecture. GO is used to assign functional enrichment scores to clusters, using a combination of specially developed techniques and general statistical methods. These results can be explored using the in built ontology browsing tool or through the generated web pages. SeqExpress also supports numerous data transformation, projection, visualization, file export/import, searching, integration (with R), and clustering options. gene, gene expression, function, analysis, visualization, statistical analysis, windows, c#, gene function, chromosome location, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Gene Expression Omnibus
PMID:14988116 Free nlx_149285, biotools:seqexpress https://bio.tools/seqexpress SCR_007075 2026-09-03 04:59:35 0
DOAF
 
Resource Report
Resource Website
1+ mentions
DOAF (RRID:SCR_015666) DOAF data or information resource, database, portal, project portal Project portal for a collaborative database aiming to provide a comprehensive annotation to human genome.It uses the computable, controlled vocabulary of Disease Ontology (DO) and NCBI Gene Reference Into Function (GeneRIF). disease ontology, annotation, collaboration, collaborative project, java, perl, rubby uses: Human Disease Ontology
is related to: NUgene Project
is related to: Gene Ontology
is related to: OBO
has parent organization: Northwestern University; Illinois; USA
NCRR 1R01RR025342;
CTSA UL1RR025741
PMID:23251346 Public, Available for download, Tutorial Available SCR_015666 Disease Ontology Annotation Framework, Disease Ontology Annotation Framework (DOAF) 2026-09-03 05:00:27 1
AnimalTFDB
 
Resource Report
Resource Website
100+ mentions
AnimalTFDB (RRID:SCR_001624) AnimalTFDB data or information resource, database A comprehensive transcription factor (TF) database in which they identified and classified all the genome-wide TFs in 50 sequenced animal genomes (Ensembl release version 60). In addition to TFs, it also collects transcription co-factors and chromatin remodeling factors of those genomes, which play regulatory roles in transcription. Here they defined the TFs as proteins containing a sequence-specific DNA-binding domain (DBD) and regulating target gene expression. Currently, the AnimalTFDB classifies all the animal TFs into 72 families according to their conserved DBDs. Gene lists of transcription factors, transcription co-factors and chromatin remodeling factors of each species are available for downloading., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. transcription factor, dna-binding domain, transcription co-factor, chromatin remodeling factor, gene structure, functional domain, go annotation, protein interaction, ortholog, paralog, 3d structure, pathway, protein-protein interaction, binding site, target, data set, image collection, 3d spatial image, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Ensembl
has parent organization: Huazhong University of Science and Technology; Wuhan; China
Huazhong University of Science and Technology; Wuhan; China ;
Fundamental Research Funds for the Central Universities 2010MS045;
National Natural Science Foundation of China 31171271
PMID:22080564 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01856, nlx_153892, biotools:animal_tfdb https://bio.tools/animal_tfdb SCR_001624 Animal Transcription Factor Database 2026-09-03 05:01:05 292
Automated Microarray Pipeline
 
Resource Report
Resource Website
Automated Microarray Pipeline (RRID:SCR_001219) AMP analysis service resource, data analysis service, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented November 4, 2015. Web application based on the TM4 Microarray Software Suite to provide a means of normalization and analysis of microarray data. Users can upload data in the form of Affymetrix CEL files, and define an analysis pipeline by selecting several intuitive options. It performs data normalization (eg RMA), basic statistical analysis (eg t-test, ANOVA), and analysis of annotation using gene classification (eg Gene Ontology term assignment). The analysis are performed without user intervention and the results are presented in a web-based summary that allows data to be downloaded in a variety of formats compatible with further directed analysis. microarray, normalization is listed by: OMICtools
is related to: Gene Ontology
has parent organization: TM4
NLM R01-LM008795 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02125 http://www.tm4.org/amp.html SCR_001219 TM4 AMP, AMP: Automated Microarray Pipeline, AMP (TM4 Microarray Software Suite), TM4 Microarray Software Suite: Automated Microarray Pipeline, TM4 Microarray Software Suite: AMP 2026-09-03 05:01:13 0
WegoLoc
 
Resource Report
Resource Website
1+ mentions
WegoLoc (RRID:SCR_001402) WegoLoc analysis service resource, data analysis service, production service resource, service resource Data analysis service that predicts protein subcellular localizations of animal, fungal, plant, and human proteins based on sequence similarity and gene ontology information. subcellular localization, protein is listed by: OMICtools
is related to: Gene Ontology
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01636 SCR_001402 weighted gene ontology term based subcellular locallization prediction 2026-09-03 05:00:52 4
pSTIING
 
Resource Report
Resource Website
1+ mentions
pSTIING (RRID:SCR_002045) pSTIING data or information resource, database A publicly accessible knowledgebase about protein-protein, protein-lipid, protein-small molecules, ligand-receptor interactions, receptor-cell type information, transcriptional regulatory and signal transduction modules relevant to inflammation, cell migration and tumourigenesis. It integrates in-house curated information from the literature, biochemical experiments, functional assays and in vivo studies, with publicly available information from multiple and diverse sources across human, rat, mouse, fly, worm and yeast. The knowledgebase allowing users to search and to dynamically generate visual representations of protein-protein interactions and transcriptional regulatory networks. Signalling and transcriptional modules can also be displayed singly or in combination. This allow users to identify important "cross-talks" between signalling modules via connections with key components or "hubs". The knowledgebase will facilitate a "systems-wide" understanding across many protein, signalling and transcriptional regulatory networks triggered by multiple environmental cues, and also serve as a platform for future efforts to computationally and mathematically model the system behavior of inflammatory processes and tumourigenesis. protein-protein, protein-lipid, protein-small molecule, ligand-receptor interaction, receptor-cell type, transcriptional regulatory module, signal transduction module, inflammation, cell migration, tumorigenesis, protein-protein interaction, transcriptional regulatory network, signalling pathway, interaction, protein interaction, motif, domain, protein, gene is listed by: OMICtools
is related to: Gene Ontology
has parent organization: University College London; London; United Kingdom
Inflammation, Tumor, Cancer PMID:16381926 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01916 SCR_002045 Protein Signalling Transcriptional Interactions and Inflammation Networks Gateway, Protein Signalling Transcriptional Interactions & Inflammation Networks Gateway 2026-09-03 05:00:59 2
GOToolBox Functional Investigation of Gene Datasets
 
Resource Report
Resource Website
10+ mentions
GOToolBox Functional Investigation of Gene Datasets (RRID:SCR_003192) GOToolBox service resource, software resource, source code The GOToolBox web server provides a series of programs allowing the functional investigation of groups of genes, based on the Gene Ontology resource. The web version of the GOToolBox is free for non-commercial users only. Users from commercial companies are allowed to use the site during a reasonable testing period. For a regular use of the web version, a license fee should be paid. We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. GO annotations can also be constrained to a slim hierarchy or a given level of the ontology. The source codes are available upon request, and distributed under the GPL license. Platform: Online tool gene, annotation, statistical analysis, slimmer-type tool, function, cluster, gene association, gene ontology is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Center for Genomic Regulation; Barcelona; Spain
Action Bioinformatique inter-EPST ;
French Ministere de l'Education de la Recherche et de la Technologie ;
Fondation pour la Recherche Medicale
PMID:15575967 Free, Freely available nif-0000-30623 http://burgundy.cmmt.ubc.ca/GOToolBox/ SCR_003192 GOToolBox - Functional Investigation of Gene Datasets, GOToolBox : Functional Investigation of Gene Datasets 2026-09-03 05:01:16 35
Biomine
 
Resource Report
Resource Website
1+ mentions
Biomine (RRID:SCR_003552) Biomine data or information resource, database, service resource Service that integrates cross-references from several biological databases into a graph model with multiple types of edges, such as protein interactions, gene-disease associations and gene ontology annotations. Edges are weighted based on their type, reliability, and informativeness. In particular, it formulates protein interaction prediction and disease gene prioritization tasks as instances of link prediction. The predictions are based on a proximity measure computed on the integrated graph. gene, protein, genetics, visualization, connection, biological entity, protein interaction, disease gene, link prediction is related to: Entrez Gene
is related to: Gene Ontology
is related to: HomoloGene
is related to: InterPro
is related to: OMIM
is related to: STRING
is related to: UniProtKB
is related to: UniProt
is related to: GoMapMan
has parent organization: University of Helsinki; Helsinki; Finland
PMID:22672646 nlx_157687 SCR_003552 2026-09-03 05:01:33 4
SEGS
 
Resource Report
Resource Website
1+ mentions
SEGS (RRID:SCR_003554) SEGS analysis service resource, data analysis service, production service resource, service resource A web tool for descriptive analysis of microarray data. The analysis is performed by looking for descriptions of gene sets that are statistically significantly over- or under-expressed between different scenarios within the context of a genome-scale experiments (DNA microarray). Descriptions are defined by using the terms from the Gene Ontology (GO), the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and gene-gene interactions found in the ENTREZ database. Gene annotations by GO and KEGG terms can also be found in the ENTREZ database. The tool provides three procedures for testing the enrichment of the gene sets (over- or under-expressed): Fisher's exact test, GSEA and PAGE, and option for combining the results of the tests. Because of the multiple-hypothesis testing nature of the problem, all the p-values are computed using the permutation testing method. microarray, pathway, gene-gene interaction, gene, interaction, annotation, gene expression, ortholog, molecular function, biological process, cellular component, enriched gene set, gene set is related to: Gene Ontology
is related to: Entrez Gene
is related to: KEGG
is related to: GoMapMan
has parent organization: Jozef Stefan Institute; Ljubljana; Slovenia
PMID:18234563 nlx_157688 SCR_003554 Search for Enriched Gene Sets 2026-09-03 05:01:27 3
T-profiler
 
Resource Report
Resource Website
10+ mentions
T-profiler (RRID:SCR_003452) T-profiler analysis service resource, data analysis service, production service resource, service resource One of the key challenges in the analysis of gene expression data is how to relate the expression level of individual genes to the underlying transcriptional programs and cellular state. The T-profiler tool hosted on this website uses the t-test to score changes in the average activity of pre-defined groups of genes. The gene groups are defined based on Gene Ontology categorization, ChIP-chip experiments, upstream matches to a consensus transcription factor binding motif, and location on the same chromosome, respectively. If desired, an iterative procedure can be used to select a single, optimal representative from sets of overlapping gene groups. A jack-knife procedure is used to make calculations more robust against outliers. T-profiler makes it possible to interpret microarray data in a way that is both intuitive and statistically rigorous, without the need to combine experiments or choose parameters. Currently, gene expression data from Saccharomyces cerevisiae and Candida albicans are supported. Users can submit their microarray data for analysis by clicking on one of the two organism-specific tabs above. Platform: Online tool expression, gene, binding, cellular, transcriptional, gene expression, microarray, gene ontology, transcription factor, binding motif, chip-chip, chip, motif, t-test, statistical analysis, transcriptome, bio.tools is listed by: Biositemaps
is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: Columbia University; New York; USA
has parent organization: University of Amsterdam; Amsterdam; Netherlands
Netherlands Foundation for Technical Research APB.5504;
NHGRI R01HG003008
PMID:15980543 Free for academic use nif-0000-33354, biotools:t-profiler https://bio.tools/t-profiler SCR_003452 T-profiler: Scoring the Activity of Pre-defined Groups of Genes Using Gene Expression Data 2026-09-03 05:01:15 11

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