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URL: http://www.bioconductor.org/packages/release/bioc/html/SamSPECTRAL.html
Proper Citation: SamSPECTRAL (RRID:SCR_001858)
Description: Software that identifies cell population in flow cytometry data. It demonstrates significant advantages in proper identification of populations with non-elliptical shapes, low density populations close to dense ones, minor subpopulations of a major population and rare populations. It samples large data such that spectral clustering is possible while preserving density information in edge weights. More specifically, given a matrix of coordinates as input, SamSPECTRAL first builds the communities to sample the data points. Then, it builds a graph and after weighting the edges by conductance computation, the graph is passed to a classic spectral clustering algorithm to find the spectral clusters. The last stage of SamSPECTRAL is to combine the spectral clusters. The resulting connected components estimate biological cell populations in the data sample.
Synonyms: SamSPECTRAL - Identifies cell population in flow cytometry data
Resource Type: software resource
Defining Citation: PMID:20667133
Keywords: software package, mac os x, unix/linux, windows, r, cell biology, clustering, flow cytometry, stem cell, bio.tools
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