Leaving Community
Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.
Hypothesis Center
Tutorial Listing
Evidence for signaling nodes that regulate my biological process of interest [1 Use Case]
-
Transcriptomic evidence for regulation of human cell cycle genes by FGF receptor signaling
This tutorial can assist you in finding evidence for cell cycle genes that are regulated by human FGF receptors.
SPP is a hypothesis generation platform that allows users to repurpose millions of biocurated 'omics data points to make high-confidence connections between signaling pathway nodes and transcriptional targets in their biological system of interest.Resources Used: Signaling Pathways Project (RRID:SCR_018412);
Evidence for signaling nodes that regulate my gene set of interest [1 Use Case]
-
Transcriptomic evidence for regulation of a mouse gene set by members of the E3 ubiquitin ligases
This tutorial can assist you in finding evidence for genes that are regulated by E3 ubiquitin ligases.
SPP is a hypothesis generation platform that allows users to repurpose millions of biocurated 'omics data points to make high-confidence connections between signaling pathway nodes and transcriptional targets in their biological system of interest.Resources Used: Signaling Pathways Project (RRID:SCR_018412);
Evidence for target genes of my signaling node of interest [2 Use Cases]
-
This tutorial can assist you in finding evidence for human genes that are most transcriptionally responsive to insulin receptor signaling.
SPP is a hypothesis generation platform that allows users to repurpose millions of biocurated 'omics data points to make high-confidence connections between signaling pathway nodes and transcriptional targets in their biological system of interest.Resources Used: Signaling Pathways Project (RRID:SCR_018412);
-
ChIP-Seq evidence for regulation of a human gene set by E2F/FOX transcription factors
This tutorial can assist you in finding evidence for human genes that are regulated by E2F/FOX transcription factors.
SPP is a hypothesis generation platform that allows users to repurpose millions of biocurated 'omics data points to make high-confidence connections between signaling pathway nodes and transcriptional targets in their biological system of interest.Resources Used: Signaling Pathways Project (RRID:SCR_018412);
Evidence for genes & signaling pathways that involved in my physiological events [2 Use Cases]
-
This tutorial can assist you in finding evidence for gene sets and signaling pathways that are involved in regulation of glucose tolerance.
dkNET Hypothesis Center creates an integrator tool that brings the Signaling Pathways Project (SPP) and The Mouse Metabolic Phenotyping Centers (MMPC) together to connect cellular signaling pathways and gene expression with physiological phenotypes. This one-of-a-kind tool makes it easier for researchers to find gene sets and signaling pathways relevant to mouse and human phenotypes for generating hypotheses.Resources Used: Signaling Pathways Project (RRID:SCR_018412); National Mouse Metabolic Phenotyping Centers (RRID:SCR_008997);
-
This tutorial can assist you in finding evidence for gene sets and signaling pathways that are involved in regulating circulating insulin level.
dkNET Hypothesis Center creates an integrator tool that brings the Signaling Pathways Project (SPP) and The Mouse Metabolic Phenotyping Centers (MMPC) together to connect cellular signaling pathways and gene expression with physiological phenotypes. This one-of-a-kind tool makes it easier for researchers to find gene sets and signaling pathways relevant to mouse and human phenotypes for generating hypotheses.Resources Used: Signaling Pathways Project (RRID:SCR_018412); National Mouse Metabolic Phenotyping Centers (RRID:SCR_008997);
About
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant 2U24DK097771-09.
Recent News Entries
Contact Us
Email: info_at_ dknet.org
