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dkNET community events and announcements in April, 2023

  • 05:37pm March 30, 2023
  • Ko-Wei Lin

Dear dkNET Community,

dkNET provides updates on activities of interest to the NIDDK-supported community. You could keep up to date on these activities through our Twitter feed @dkNET_info, through our Community Calendar, or through dkNET e-mail list. If you have an event or funding opportunities you'd like to advertise, please contact us info_at_dknet.org.


dkNET News

  • Upcoming dkNET Webinars: dkNET New Investigator Pilot Program in Bioinformatics Awardee Webinar Series (1) “Single Molecule Spatial Transcriptomics: Interpreting the Spatial Expression of RNAs from FISH Images” presented by Dr. Jing Liu on Friday, Apr. 21, 2023, 11 am - 12 pm PT: https://dknet.org/about/blog/2603
     (2) "Integrating regulatory Maternal Obesity Programs Controlling Adipose Tissue Cellular Complexity" presented by Nabil Rabhi on Friday, May 12, 2023, 11 am - 12 pm PT. https://dknet.org/about/webinar

  • Recordings and Slides are Now Available: (1) dkNET Office Hours - "Are You Ready for 2023: New NIH Data Management and Sharing Mandates" on Mar. 3, 2023: Slides; Recording. (2) dkNET Pilot Program Awardee Webinar Series " Estimating Relative Beta-Cell Function During Continuous Glucose Monitoring” presented by Joon Ha on Mar. 10, 2023: Slides; Recording.


  • The 2023 dkNET Summer of Data Student Program Are you a student, or do you know any students, who are doing research in NIDDK fields such as diabetes, kidney, digestive, obesity, metabolic, liver, endocrine, urology, nutrition or hematology diseases? The dkNET Summer of Data Student Program is a 6-week program providing an opportunity for students (high school to Masters/ PhD graduate) to learn rigor and reproducibility practices, FAIR data management, & dkNET resources and apply them to their research projects! This program requires that students be involved with an NIDDK-related research lab during the summer of 2023. dkNET offers limited scholarships to student applicants. Application due date: Apr. 24, 2023.

Events in April 2023

Apr. 02, 2023

NIDDK Workshop Registration Deadline: Neural Plasticity in Energy Homeostasis and Obesity

The purpose of this virtual workshop is to bring together experts in the neural plasticity of central and peripheral circuits that control food intake, energy homeostasis, and metabolism in healthy and unhealthy states, such as obesity, to review the science, identify knowledge gaps regarding the functional plasticity within these circuits, and identify high priority areas of research that may lead to therapeutic advances for obesity and other disorders related to metabolic dysregulation and food intake. Workshop dates: April 13-14, 2023.

More information: https://www.niddk.nih.gov/news/meetings-workshops/2023/neural-plasticity-in-energy-homeostasis-and-obesity


Apr. 03, 2023

Registration deadline: NIDDK NMRI Annual Workshop 2023

The meeting is open to all underrepresented minority investigators, including post-graduate doctoral students, who are conducting biomedical research in the fields of:
  • Diabetes, endocrinology, metabolism
  • Digestive and liver diseases, nutrition
  • Kidney, urologic, and hematologic diseases
Meeting dates: April 19-21, 2023

Location:  Bethesda, MD, USA

More information: https://www.niddk.nih.gov/news/meetings-workshops/2023/nmri-annual-meeting-2023


Apr. 12, 2023

Registration deadline: NIDDK K Awardees' Workshop

This workshop will offer NIDDK career development awardees an in-depth view of the National Institutes of Health (NIH), NIDDK, and the grant review process. The agenda will include ample time for questions and answers. The workshop will be held at Lister Hill Center Auditorium. Dates: April 20-21, 2023. 

Location: Bethesda, MD, USA

More information: https://www.niddk.nih.gov/news/meetings-workshops/2023/k-awardees-workshop


Apr. 13-14, 2023

NIDDK Workshop: Neural Plasticity in Energy Homeostasis and Obesity

The purpose of this virtual workshop is to bring together experts in the neural plasticity of central and peripheral circuits that control food intake, energy homeostasis, and metabolism in healthy and unhealthy states, such as obesity, to review the science, identify knowledge gaps regarding the functional plasticity within these circuits, and identify high priority areas of research that may lead to therapeutic advances for obesity and other disorders related to metabolic dysregulation and food intake. Registration deadline: April 2, 2023.

More information: https://www.niddk.nih.gov/news/meetings-workshops/2023/neural-plasticity-in-energy-homeostasis-and-obesity


Apr. 19-21, 2023

NIDDK NMRI Annual Workshop 2023

The meeting is open to all underrepresented minority investigators, including post-graduate doctoral students, who are conducting biomedical research in the fields of:
  • Diabetes, endocrinology, metabolism
  • Digestive and liver diseases, nutrition
  • Kidney, urologic, and hematologic diseases
Registration deadline: April 3, 2023
Abstract deadline: March 27, 2023

Location:  Bethesda, MD, USA

More information: https://www.niddk.nih.gov/news/meetings-workshops/2023/nmri-annual-meeting-2023



Apr. 20-23, 2023

American Physiology Society Summit

One hundred thirty-six years after the American Physiological Society (APS) was established, we mark a moment in history with a significant and unprecedented commitment to physiologists worldwide. We’re launching a meeting designed by and for physiologists with speakers to spark inspiration, spaces to evoke collaboration and a setting in sunny Long Beach where you can put aside the stresses of everyday life and focus on your shared passion for science.

Location:  Long Beach, CA, USA

More information: https://www.physiology.org/professional-development/meetings-events/american-physiology-summit-2023?SSO=Y



Apr. 20-21, 2023

NIDDK K Awardees' Workshop

To facilitate the career development of National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)–supported investigators and help in their transition to independent research careers, the NIDDK is sponsoring a K Awardees’ Workshop to be held April 20–21, 2023. Participation in the workshop is by invitation only. The purpose of the workshop is to offer NIDDK career development awardees an in-depth view of the National Institutes of Health (NIH), NIDDK, and the grant review process. The workshop will provide an opportunity to become familiar with various NIH staff roles and with the types of grant support and resources available, as well as the opportunity to query program staff on navigating the R01 submission process. Senior investigators from the NIDDK research community will provide grant-writing tips and career advice. The agenda will include ample time for questions and answers during the 2-day workshop. The workshop location and format will encourage networking among participants. NIDDK program staff will be available for discussion of future individual research projects and research grant applications. Registration deadline: April 12, 2023.

Location: Bethesda, MD, USA

More information: https://www.niddk.nih.gov/news/meetings-workshops/2023/k-awardees-workshop


Apr. 21, 2023

dkNET Webinar: Single Molecule Spatial Transcriptomics: Interpreting The Spatial Expression Of RNAs From FISH Images

dkNET New Investigator Pilot Program in Bioinformatics Awardee Webinar Series

Join dkNET Webinar on Friday, April 21, 2023, 11 am - 12 pm PDT

Presenter: Jing Liu, Ph.D. Assistant Professor, Department of Physics, Indiana University-Purdue University Indianapolis, Member of Center for Computational Biology and Bioinformatics, and Center for Diabetes and Metabolic Diseases; Associate member of Simon Comprehensive Cancer Center, Indiana University School of Medicine.

Abstract 

Recently emerged spatial transcriptomics approaches combine the RNA sequencing (RNA-Seq) with spatial localization to reveal the spatial heterogeneity of transcriptome in pancreatic islet. However, the interrogation of the transcriptomic expression in a single cell is missing, particularly the spatial distribution of each RNA molecule. Here we proposed a quantitative approach to quantify the spatial distribution of RNA molecules in a single cell, and gave a case study to investigate the miRNA expression in single ? cells obtained from human pancreatic tissues. A multi-dimensional quantitative model was established to describe the spatial distribution of individual RNAs as a library of “features”, which includes RNA expression, locations, clustering/dispersion, and reciprocal positions. In particular, the degree of RNA clustering/dispersion was described by the mathematical model of clusters, i.e. Ripley's H function. Extracted features are then analyzed by statistical distribution modelling and supervised machine learning. Machine learning enables the classification of 3 groups of ? cells (control, T1D, and AAb+) using spatial transcriptomic features with high accuracy (65%±3%). Furthermore, it offers quantitative evaluation of those distinctive features contributing to the classification and phenotyping. All evidence suggests the spatial heterogeneity of transcriptome of ? cells in T1D, and this transcriptomic disparity has been leveraged to classify ? cells into different pathological conditions. This work will not only disclose fundamental mechanisms that are associated with ? cell survival in T1D; more practically, it could lead to important transcriptomic features of ? cells that could have clinical relevance in stratifying the T1D phenotypes.

More information: https://dknet.org/about/blog/2603


Apr. 24, 2023

NIDDK Workshop Registration Due: Fifth Artificial Pancreas Workshop "Enabling Fully Automation, Access, and Adoption

The purpose of this workshop is to discuss in a multi-disciplinary forum, the current and potential future challenges for the development, testing, accessibility and adoption of fully automated diabetes management technologies and their components. Topics to be discussed include:

  1. Lessons learned from Clinical Trials. Clinical testing modalities for real world translatability.
  2. Discussion of current state of interoperability and perspectives for the future.
  3. Adaptation of systems throughout the life span and to special populations.
  4. Potential benefits of multihormone closed loop systems and the use of adjuvant therapies.
  5. Artificial intelligence/ ML and integration strategies for personalized systems.
  6. Technical challenges and potential solutions in glucose sensing and more physiological and durable insulin/pancreatic hormones delivery.
  7. Human psychosocial factors, quality of life, ethical considerations and health disparities in the adoption and access to these technologies.
  8. Prospective areas of research emphasis to accelerate the availability of wearable, affordable, accessible, and more user-friendly systems for individuals with diabetes”

This event has been organized in collaboration with the Diabetes Technology Society, the Helmsley Charitable Trust, the JDRF, and the U.S. Food and Drug Administration.

Workshop dates: May 1-2, 2023

Location: Bethesda, MD, USA

More information: https://www.niddk.nih.gov/news/meetings-workshops/2023/fifth-artificial-pancreas-workshop

Apr. 24-26, 2023

The Fourth Summit: Geroscience for the Next Generation A Hybrid Event

The Fourth Summit: Geroscience for the Next Generation is a conference organized by the Geroscience Interest Group of the National Institutes of Health, which aims to highlight the importance of implementing geroscience research to address health disparities and comorbidities in aging populations. The conference will explore the development of new measures reporting health and function in aging, the use of mathematical modeling in aging research, and the importance of evidence-based inclusive geroscience in medical practice. Additionally, the conference will discuss the feasibility, design, and implementation of geroscience clinical trials. The summit will generate a summary document of the discussions identifying gaps and opportunities in the field and actionable next steps to advance geroscience. The conference will be held as a hybrid event with in-person attendance at the Natcher Conference Center, NIH, and online attendance through Zoom Webinar and NIH Videocast on April 24-26, 2023.

Location:  Bethesda, MD, USA

More information: https://event.roseliassociates.com/nia-geroscience-summit/



Funding Opportunities Information and Deadlines in April 2023

Apr. 11, 2023

NIH Funding Opportunity Application Due: Notice of Special Interest (NOSI): Administrative Supplements to Support the Exploration of Cloud in NIH-supported Research

The goal of this Notice of Special Interest (NOSI) is to encourage and enable researchers to explore and test opportunities to enhance their research projects by incorporating cloud capabilities. Projects already using cloud may apply to explore and test cloud capabilities not yet leveraged. Projects supported through this NOSI should result in improved understanding of how to best use cloud resources. Specifically, this opportunity is to support proof-of-concept explorations, measurements, or other tests of the suitability and feasibility of using cloud resources to enhance NIH-supported research projects. Proposed projects should result in a better understanding of which use cases are cost effective or enable significant enhancements to strategic data science goals such as facilitating new discoveries through access to modern computing and storage platforms at scale; broadening and diversifying participation in NIH research; facilitating the interoperability of NIH data, for example, by enabling multi-cloud or cross-cloud architectures; enhancing existing projects by utilizing new cloud technologies; or improving the computational and cost efficiencies of research. Applicants should consider the expertise needed for the proposed work and incorporate new partners, as needed.

More information:

 https://dknet.org/about/dknetnews/2583


Apr. 17, 2023

NIH Funding Opportunity Application Due: Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH.  The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Courses for Skills Development. Letter of Intent Due Date: March 17, 2023; Application Due Date: April 17, 2023.

More information:

https://grants.nih.gov/grants/guide/rfa-files/rfa-od-23-003.html

Apr. 17, 2023

Innovative Science Accelerator Program (ISCAC) Funding Opportunity Application Deadline

ISAC is seeking applications for exceptionally innovative, disruptive research relevant to KUH communities that has potential to lead to paradigm-shifting results. Application deadline: April 17, 2023.

More information: https://isac-kuh.org/shared/fundingPrograms.aspx



Apr. 24, 2023

Application deadline: dkNET Summer of Data Student Program

The Summer of Data program provides students the opportunity to learn data management, FAIR data and rigor and reproducibility skills while performing their research.  It is a 6 week virtual summer program where students engage in weekly sessions with dkNET staff and associates to learn about how to use dkNET and other tools to support their research, while engaging in research projects within their labs.  A $500 stipend is provided.  The intent of this program is to enable students, over a 6-week period, to use the dkNET portal to support their own research or that of their PI’s. The intent is they will learn best practices to enhance rigor and reproducibility and learn the basics of good data management by following the FAIR (Findable, Accessible, Interoperable, Reusable) data principles. Preferences will be given to those research projects that would most benefit from the types of services offered by dkNET, e.g., projects that involve antibodies, genetically modified organisms, and ‘omics’ data in the areas of focus for NIDDK including diabetes, obesity, nutrition, digestive, kidney, liver, urologic, endocrine, metabolic, bone, and blood diseases.

More information: https://dknet.org/about/Summer-Program


Apr. 25, 2023

NIH Funding Opportunity First Available Application Due: Notice of Special Interest (NOSI): Administrative Supplements to Support Collaborations to Improve the AI/ML-Readiness of NIH-Supported Data

This Notice announces the availability of supplements to active grants which are intended to support collaborations that bring together expertise in biomedicine, data management, and artificial intelligence and machine learning (AI/ML) to make NIH-supported data useful and usable for AI/ML analytics. This initiative is aligned with the NIH Strategic Plan for Data Science, which describes actions aimed at modernizing the biomedical research data ecosystem and making data FAIR (Findable, Accessible, Interoperable, and Reusable) with high impact for open science. For the purposes of this Notice, AI/ML is inclusive of machine learning (ML), deep learning (DL), and neural networks (NN). First Available Application Due Date: April 25, 2023.

More information: https://dknet.org/about/dknetnews/2594


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About

The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant 2U24DK097771-09.

Recent News Entries

dkNET Office Hours: NIH Data Management and Sharing Mandates

Join HIRN Webinar: Emerging Role for Tissue-Specific Extracellular Vesicles in Disease Diagnosis: Implications for T1D on April 23

dkNET Webinar "Texera: A Scalable Cloud Computing Platform for Sharing Data and Workflow-Based Analyses"

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Email: info_at_ dknet.org

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