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dkNET Blog
Signaling Pathways Project Analysis Generates Hypotheses Around Host Responses to SARS-CoV-2 Infection in COVID-19
- 04:09pm June 23, 2021
- 1421 views
- Hypothesis Center, Stories of Discovery, SPP, News
Integrating archived SARS-CoV-2 infection transcriptomic datasets with signaling node transcriptomic datasets, SPP analytics generated novel hypotheses around SARS-CoV-2 infection that were subsequently independently confirmed by wet bench research laboratories.
Congratulations! SPP lead Dr. Neil McKenna and collaborators published a paper "A human liver chimeric mouse model for non-alcoholic fatty liver disease" in JHEP Reports
dkNET Hypothesis Center - Signaling Pathways Project (SPP) team collaborated with liver researchers and published a paper "A human liver chimeric mouse model for non-alcoholic fatty liver disease" in JHEP Reports. Scientists used SPP's NAFLD consensome to discover that NAFLD livers, compared to normal ones, have consistently higher levels of cholesterol synthesis enzyme transcripts!
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The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant 2U24DK097771-09.
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