[Recorded Webinar and Slides are Available Now!] dkNET Webinar: Visualizing Organelle and Cell Longevity In Situ

*Watch recorded webinar here: https://youtu.be/-EgBNITq_2I

*Webinar slides: https://www.slideshare.net/dkNET/dknet-webinar-visualizing-organelle-and-cell-longevity-in-situ-052022

dkNET New Investigator Pilot Program in Bioinformatics Awardee Webinar Series

Join dkNET Webinar on Friday, May 20, 2022, 11 am - 12 pm PDT

Presenter: Rafael Arrojo e Drigo, Ph.D. Assistant Professor, Department of Molecular Physiology and Biophysics, Vanderbilt University

Abstract 

Cells in largely post-mitotic organs can be as old as their host organism. These long-lived cells (LLCs) face a lifelong demand for performance to maintain organ function and are constantly exposed to drivers of molecular and cellular damage. Accordingly, dysfunction of LLCs is associated with aging and age-associated disease processes. Understanding cellular longevity mechanisms requires the identity and distribution pattern of LLCs. We developed imaging tools to quantify the age of cells in situ, which led to the discovery of new LLC types throughout the mouse body. This includes different cell types in the pancreas, where most beta cells can be as old as neurons in the brain. In this presentation, I will show how we apply different microscopy tools to bridge spatial and temporal scales in biology to quantify protein complex, organelle, and cell age in tissues. Applicable to virtually any cell, this imaging platform can reveal the temporal dynamics and longevity of structural components in vivo and their contribution to cell and tissue organization and function.

Dial-in Information:  https://uchealth.zoom.us/meeting/register/tZAlfu6hqz0oGty2d9-2_LDJXYl-8B4SElnP

Upcoming webinars schedule: https://dknet.org/about/webinar