dkNET community events and announcements in December, 2019
- 07:37pm December 2, 2019
- Ko-Wei Lin
Dear dkNET Community,
dkNET provides updates on activities of interest to the NIDDK-supported community. You could keep up to date on these activities through our Twitter feed @dkNET_info, through our Community Calendar, or through dkNET e-mail list. If you have an event or funding opportunities you'd like to advertise, please contact us info_at_dknet.org.
dkNET News
- Meet us at ASCB/EMBO Annual Meeting in Washington DC! For those who will be attending the 2019 ASCB/EMBO Annual Meeting, don't forget to stop by dkNET booth #232! dkNET team will be there to give you a demo about what's new at dkNET and answer your questions. Come learn about the 2020 dkNET Summer of Data Student Internship Program, new bioinformatics pilot program, and more! We would love to hear your feedback about our new portal so we can continue to improve our service to you as well! If you want to meet at a specific date/time to connect with the dkNET team at ASCB/EMBO Meeting? Send an email to info@dknet.org to book a spot.
Schedule
- dkNET booth #232, 9:30 am - 4:00 pm EST, December 8-10, 2019
- Poster presentations, 1:30 pm- 3:00 pm EST, December 9, 2019
(1) Identification Of Biosamples Using NIDDK Information Network (dkNET) Resource Reports: An Integrated Resource Network Platform That Helps Improve Rigor And Reproducibility (P933, B54)
(2) Improving Awareness About Scientific Rigor And Reproducibility Through NIDDK Information Network (dkNET) Tools And Training Resources (P904, B24)
- dkNET New Investigator Pilot Program in Bioinformatics As high throughput technologies become routine for individual laboratories in biomedical research, there is a growing need to develop a workforce that can use and further refine the computational approaches needed to interrogate complex data. This pilot program, through the NIDDK Information Network (dkNET), is designed to encourage new investigators to apply innovative bioinformatics approaches to important research problems in Diabetes, Endocrinology and Metabolic Diseases (DEMD). The dkNET New Investigator Pilot Program is designed to: (i) facilitate the ability of Early Stage and New Investigators with computational and bioinformatics expertise to pursue research questions in DEMD, or (ii) allow Early Stage and New PIs currently pursuing DEMD-related research to explore incorporating computational, statistical, and/or bioinformatics approaches into their research projects. Letter of Intent Due Date: January 14, 2020. Application Due Date: February 14, 2020.
Events in December, 2019
Abstract deadline: Keystone Symposia - New Insights into the Biology of Exercise
Exercise and regular physical activity are widely recognized to be important for maintaining overall health and wellness. Furthermore, exercise has been proven to be an effective therapy for the prevention and treatment of a variety of diseases including diabetes, obesity, cardiovascular disease, and cancer. The physiological response of selected tissues, such as skeletal muscle, heart, liver, adipose, and brain to exercise has been studied to varying degrees in healthy and unhealthy individuals; however, the cellular and molecular mechanisms underlying the acute responses and training adaptations to exercise remain poorly defined. The study of exercise is not a new field but is receiving increased interest because of the many health-promoting benefits of regular aerobic and resistance exercise. This conference includes selected speakers who can present new findings related to the response of multiple organs/tissues (skeletal muscle, liver, adipose tissue, heart, vascular, brain) to exercise in both animal models and humans. The overarching goals for the conference are to 1) encourage discussion of the integrative multiple organ response to exercise, 2) encourage discussion and integration of basic and translational research, and 3) provide an environment for investigators to network and initiate new collaborations.
Location: Keystone, CO 80435, USA
More information: http://www.keystonesymposia.org/index.cfm?e=Web.Meeting.Summary&\;meetingid=1712&\;subTab=summary
NIDDK Meeting: Collaborating for the Advancement of Interdisciplinary Research in Benign Urology
The purpose of the CAIRIBU (Collaborating for the Advancement of Interdisciplinary Research in Benign Urology) meeting is to bring together the Directors of the NIDDK U54 O?Brien Urology Centers and their research teams, the Directors and research teams of the P20 Developmental Centers for Interdisciplinary Research in Benign Urology, and the Directors for the Multidisciplinary K12 Urologic Research (KURe) and Urologic Epidemiology (KEpi) Career Development Program and their scholars. This meeting will promote interactions between Centers and Programs, the development and sharing of research resources, and the advancement of students and early investigators in the field of benign urology research.
Location: Kansas City, MO, USA
More information: https://www.niddk.nih.gov/news/meetings-workshops/2019/collaborating-advancement-interdisciplinary-research-benign-urology
Scholarship Application Deadline Deadline: Keystone Symposium - Integrating Metabolism and Immunity
Traditionally, metabolism and immunity have been perceived as two distinct systems with distinct functions: metabolism regulates the disposal and transformation of nutrients, whereas the immune system is responsible for host defense. However, in a broader sense, these two processes are both an organism’s response to stressors, with the aim of restoring homeostasis. An increasing amount of evidence has demonstrated that the chronic activation of the immune system associated with overnutrition may be deleterious, contributing importantly to diabetes and long-term complications, such as cardiovascular disorders. Such dysregulation of the immune system may reflect the duration and magnitude of the metabolic stress, along with genetic predispositions. Accordingly, anti-inflammatory treatments of metabolic diseases emerge as therapies interfering with the pathogenesis of these illnesses and offer disease-modifying potential. Therefore, it is critical that clinical translation be based on an understanding of the physiology and pathophysiology of the role of the immune system in metabolism. This conference will bring together basic scientists and clinicians from both disciplines in order to spark innovative ways of understanding the interactions between the immune system and metabolism. The conference organizers anticipate that the conference will lead to the development of novel therapeutic concepts based on the pathways underlying the pathogenesis of diseases rather than on the manifestation of symptoms belonging to a specific clinical discipline.
Location: Keystone, CO 80435, USA
More information: http://www.keystonesymposia.org/index.cfm?e=Web.Meeting.Program&\;meetingid=1690&\;subTab=program
Dec. 05, 2019
JAX Webinar: Generating Better Mouse Models for Your Research: Approaches and Considerations
Do you need a unique mouse model that does not exist or is not available? Mouse model generation is more accessible and cost-effective than ever, but the number of options of background strains and techniques adds some complexity to the process. During this webinar, we will discuss approaches and considerations for mouse model generation, including:
- Strategies to generate indel, knockout, and knockin mutations using CRISPR/Cas9, transgenics, and ES cells
- Choosing the optimal genetic background for your new mouse model
- Selecting founder mice, breeding strategies, and phenotyping
- Streamlining new model generation using The Jackson Laboratory’s expertise and services
More information: https://jackson.jax.org/JAX-Webinar-12052019.html?utm_source=email&\;utm_medium=Invite&\;utm_campaign=DEC_WEB_05
ASCB/EMBO 2019 *Meet the dkNET team!
The 2019 joint meeting of the American Society for Cell Biology (ASCB) and European Molecular Biology Organization (EMBO) will focus on cell biology as the fundamental basis of biology, and will offer sessions on emerging topics such as non-traditional model organisms, and the use of computational modeling and biophysics to “Build the Cell from the Ground Up.”
Location: Washington, DC, USA
More information: https://www.ascb.org/2019ascbembo
PKDnetwork webinar: Major Depressive Disorder in Chronic Kidney Disease
The burden of Chronic Kidney Disease (CKD) for patients is multifactorial, including having psychiatric consequences such as Major Depressive Disorder (MDD). While the interplay between the two is not clearly defined, both CKD and MDD can impact medical outcomes. In this discussion, Drs. Bojrab (a psychiatrist) and Kang (a nephrologist) will discuss the challenges and opportunities for patients with these comorbid conditions.
Keystone Symposium Abstract Deadline: A Gut-Systemic Perspective for Metabolic Disease
Changes of the microbiome and nutrient sensing within the gut alter whole-body glucose and energy homeostasis. The underlying mechanism and the therapeutic potential of such metabolic regulation in diabetes, obesity, and related disorders remain largely unexplored. This Keystone Symposia conference aims to progressively highlight a spectrum of basic and translational investigations and discoveries that first focus on microbial-host interaction and nutrient sensing mechanisms. Other sessions focus on the interaction between the gut microbiome and nutrient sensing pathways as well as how these pathways could be targeted by small molecules and/or immunological responses within the gut to impact systemic organs and whole-body metabolic homeostasis. In summary, we anticipate this conference will foster interactions between the basic, translational, clinical and pharmaceutical researchers and promote collaborative work aimed at realizing the therapeutic potential of targeting the gut microbiota-nutrient sensing axis for the treatment of metabolic disorders.
Location: Santa Fe, NM, USA
More information: http://www.keystonesymposia.org/index.cfm?e=Web.Meeting.Summary&\;meetingid=1721&\;subTab=summary
Dec. 15, 2019
Abstract Submission Deadline: Rachmiel Levine-Arthur Riggs Diabetes Research Symposium
Funding opportunities information and deadlines in December, 2019
Dec. 01, 2019
Funding Opportunity Application Due Date: MMPC MICROMouse Program
The MMPC MICROMouse Program is a competitive grants program awarding up to $75,000 (total costs) for one year to fund research projects that have the potential to enhance and advance the mission of the MMPC as a resource for scientists using mice to study diabetes and obesity. Any independent investigator, including post-doctoral fellows, is eligible to apply. A project must be either: 1) resource-development (e.g., develop, improve, miniaturize, teach, distribute, etc. phenotyping tests for use in mice); or 2) resource-related research (e.g., a new, currently unfunded project where results have potential impact for mouse centered research in diabetes or obesity, particularly those focused on broad biological questions that impact the ability of the MMPC to meet its goals). There is no formal deadline associated with MICROMouse applications, but applications will be reviewed quarterly (March 1, June 1, September 1, December 1) and therefore should be submitted accordingly.
More information: https://www.mmpc.org/shared/microMouse.aspx
American Society of Nephrology Funding Opportunity Application Deadline: The ASN Foundation for Kidney Research
The KidneyCure Transition to Independence Grants Program provides funding for young faculty to foster evolution to an independent research career and a successful, competitive application for a National Institutes of Health (NIH) R01 grant or equivalent.
More information: https://www.asn-online.org/grants/tig/details.aspx?app=TIG
Dec. 02, 2019
American Society of Nephrology Funding Opportunity Application Deadline: Ben J. Lipps Research Fellowship Program
The goal of the Ben J. Lipps Research Fellowship Program is to fund nephrology fellows to conduct original, meritorious research projects. This program will foster the training of fellows, under the direction of a sponsor, who are highly motivated to make contributions to the understanding of kidney biology and disease. This Fellowship serves to establish the beginnings of an independent career.
More information: https://www.asn-online.org/grants/fellowships/details.aspx?app=LIPPS
NIDDK Funding Opportunity Application Due Date: Understanding the Functional Contributions and Mechanisms of Type 2 Diabetes Disease-associated Variants (UM1 Clinical Trial Not Allowed)
This Funding Opportunity Announcement (FOA) encourages applications from integrative teams and individual investigators for large-scale complex multi-disciplinary Functional Genomics Projects (FGPs) to determine the contributions and mechanisms underlying the contribution of risk-associated variants and their downstream effector transcripts for type 2 diabetes (T2D). The intent is to generate knowledge and tools to enable the identification of putative biomarkers and therapeutic targets by future efforts. Genome-wide association studies (GWAS) and other genomic studies of T2D and its complications have found many variants that are statistically associated with disease risk, disease protection, progression to complications, or other traits. However, such studies do not show which variants in genomic elements cause these effects or how they result in differences in function. Applications submitted to this RFA will systematically identify causal variants and effector transcripts associated with all known T2D risk variants, verify the role of downstream effector transcripts, build network models that explain their role(s) in T2D and its complications, and identify key readouts and modulation points in these networks. Data, tools, and reagents generated by these projects will be released rapidly to facilitate more in-depth study by the broad scientific community. Awardees to this announcement will form a Consortium with the Accelerating Medicines Partnership in Type 2 Diabetes Knowledge Portal awardee (AMP T2D KP; RFA-DK-19-505) to accomplish collective goals.
More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-19-012.html
Dec. 04, 2019
NIDDK Funding Opportunity Application Due Date: Catalyst Award In Diabetes, Endocrinology and Metabolic Diseases (DP1 Clinical Trial Not Allowed)
The Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (Catalyst-DEMD) is designed to complement NIDDK's traditional, investigator-initiated grant programs by supporting individual scientists who propose pioneering and transformational studies in DEMD topic areas. Applications should be focused on major scientific challenges, and have the potential to produce an unusually high impact on diseases and conditions that are central to the mission of NIDDK's Division of Diabetes, Endocrinology and Metabolic Diseases. To be considered responsive to this initiative, the proposed research should reflect new and novel scientific directions that are distinct from concepts and approaches being pursued in the investigator’s research program or elsewhere.
More information: https://dknet.org/about/dknetnews/1898
AASLD Funding Opportunity Application Deadline: AUTOIMMUNE LIVER DISEASES PILOT RESEARCH AWARD
The purpose of this one year, $20,000 award is to provide supplementary funding during the pilot phase of basic, translational or clinical research projects in autoimmune liver disease (e.g. autoimmune hepatitis, primary sclerosing cholangitis, primary biliary cholangitis) in preparation for future grant applications by the recipient. Projects should address focused research questions pertaining to the pathogenesis, diagnosis, management or outcome of autoimmune liver diseases in children and adults.
More information: http://www.aasldfoundation.org/awards-programs/autoimmune-liver-diseases-pilot-research-award#collapse-511-0
Endocrine Society Funding Opportunity Application Deadline: Early Investigators Awards
These awards provide monetary support to assist in the development of early career investigators and recognition of their accomplishments in areas of general endocrinology. Recipients will receive a monetary award, one-year complimentary membership to the Society, one-year complimentary access to the Society's online journals, public recognition of research accomplishments in various Society platforms and an invitation to attend the Excellence in Endocrinology event at ENDO. The annual meeting will be held on March 28-31, 2020 in San Francisco, CA.
More information: https://www.endocrine.org/awards/early-investigators-awards
Dec. 06, 2019
Endocrine Society Funding Opportunity Application Deadline: Summer Research Fellowship Excellence in Research Award
The Endocrine Society offers the Summer Research Fellowship (SRF): Excellence in Research Award (ERA) to support the continued research training and career development of SRF alumni. The Society will provide ERA winners with a travel award to ENDO, the annual meeting, where they will present their research in a special Summer Research Fellowship session. The award will include complimentary registration, airfare, lodging, and per diem.
More information: https://www.endocrine.org/awards/summer-research-fellowship-excellence-in-research-award
NIDDK Funding Opportunity Application Due Date: Bioinformatics Interdisciplinary Predoctoral Fellowships in Diabetes
This funding opportunity is to enable promising predoctoral fellows to obtain interdisciplinary training during the dissertation phase of their training from outstanding faculty sponsors in bioinformatics and scientific research relevant to the mission of NIDDK's Division of Diabetes, Endocrinology and Metabolic Diseases (DDEMD). This training will require mentorship in both bioinformatics and metabolic disease disciplines. In order to advance bioinformatics science and encourage its application to these diseases and disorders, NIDDK invites applications from individuals with novel individual development plans (IDP). The fellowship training plan should focus on interdisciplinary approaches and mentorship among data or computer science and medicine in topics related to diabetes, endocrinology and metabolic diseases.
More information: https://dknet.org/about/dknetnews/1921
Dec. 08, 2019
NIDDK Funding Opportunity Application Due Date: Bioinformatics Interdisciplinary Postdoctoral Fellowships in Diabetes, Endocrinology and Metabolic Diseases
This Funding Opportunity Annoucement (FOA) is to enable promising postdoctoral fellows to obtain interdisciplinary training from outstanding faculty sponsors in bioinformatics and scientific research relevant to the mission of NIDDK's Division of Diabetes, Endocrinology and Metabolic Diseases (DDEMD). This training will require mentorship in both bioinformatics and metabolic disease disciplines. In order to advance bioinformatics science and encourage its application to these diseases and disorders, NIDDK invites applications from individuals with novel individual development plans (IDP). The fellowship training plan should focus on interdisciplinary approaches and mentorship among data or computer science and medicine in topics related to diabetes, endocrinology and metabolic diseases.
More information: https://dknet.org/about/dknetnews/1921
