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Dear dkNET Community,
dkNET provides updates on activities of interest to the NIDDK-supported community. You could keep up to date on these activities through our Twitter feed @dkNET_info, through our Community Calendar, or through dkNET e-mail list. If you have an event or funding opportunities you'd like to advertise, please contact us info_at_dknet.org.
dkNET Updates:
Clinical Trials in Organ Transplantation (CTOT) (RRID:SCR_015859) is a project portal for a cooperative research program to improve short and long-term graft and patient survival. CTOT is an investigative consortium for conducting clinical and associated mechanistic studies that will lead to improved outcomes for transplant recipients.
Growing Gene and Cell Therapy Cooperative (RRID:SCR_015861) is a project portal for a collaboration between Boston Children’s Hospital, Cincinnati Children’s Hospital Medical Center, and the University of California Los Angeles with funding from NIH NCATS. It aims to support investigators to rapidly translate complex gene and cell therapies to early phase, investigator-initiated clinical trials.
Monogenic Diabetes Registry (RRID:SCR_015883) is a research project that aims to learn more about the number of people who have monogenic diabetes, why and how it happens, and how best to treat it. Any adult or child with a known genetic cause of diabetes may join the MODY Registry.
National Glycohemoglobin Standardization Program (RRID:SCR_015885) is a project that aims to standardize Hemoglobin A1c test results to those of the Diabetes Control and Complications Trial (DCCT) and United Kingdom Prospective Diabetes Study (UKPDS) which established the direct relationships between HbA1c levels and outcome risks in patients with diabetes.
Events in January, 2018
Jan. 21-25, 2018
Keystone Meeting: Bioenergetics and Metabolic Disease (J4)
Obesity and type 2 diabetes are major drivers of chronic disease and premature death. A promising strategy to reduce obesity and improve metabolic health is through promoting energy expenditure via thermogenesis, including obligatory(accompanies all metabolic processes) and facultative (adaptive) mechanisms. Obesity and insulin resistance also lead to profound metabolic changes in various cells/tissues that contribute to tissue dysfunction. This conference brings together basic and clinical researchers from industry and academia focused on the study of cellular and organismal energy metabolism in the context of metabolic disease. A variety of approaches and topics will be featured, including: basic mechanisms of mitochondrial and cellular energetics; the emerging role of brown and beige fat in adaptive thermogenesis; central regulation of energy expenditure; and the effects of exercise on muscle andwhole-body metabolism. In addition to the plenary sessions, the meeting will feature workshops on emerging research areas and novel therapeutic opportunities. Overall, the goals of the conference are to: 1) Provide a cutting-edge understanding of the basic mechanisms that control cellular and whole-body energetics; 2) Discuss the physiological role of brown fat and other energy expenditure pathways in humans; 3) Consider novel strategies for increasing energy expenditure and combating metabolic disease; and 4) Engage attendees in critical discussions about important areas for future research.Location: Keystone, CO, USA
More information: http://www.keystonesymposia.org/index.cfm?e=web.meeting.program&meetingid=1566
Jan. 21-25, 2018
Keystone Symposia: Organ Crosstalk in Obesity and NAFLD
Neural and humoral communication among peripheral organs and the brain is critical in coordinating whole body energy homeostasis in health and disease. Nutrient and hormone sensing take place in multiple organs with the central nervous system as a site of integration of these diverse signals, governing this coordination. Within this multi-organ framework, the liver occupies a central role in determining systemic glucose and lipid metabolism in obesity and clinically relevant metabolic pathophysiologyMore information: http://www.keystonesymposia.org/index.cfm?e=web.meeting.summary&meetingid=1565&subtab=summary
Jan. 22-24, 2018
NIH Data Science Hackathon
Location: Bethesda, MD, USA
More information: https://dknet.org/about/dknetnews/1042
Jan. 29, 2018
Application Deadline: 2018 NIDDK Medical Student Research Program in Diabetes and Obesity
The Medical Student Summer Research Program in Diabetes and Obesity is sponsored by the National Institutes of Health through the NIDDK and allows medical students to conduct research under the direction of an established scientist in the areas of diabetes, hormone action, physiology, islet cell biology, obesity or complications at an institution with one of the NIDDK-funded Diabetes Centers during the summer between the first and second year or second and third year of medical school. Please remember that you must work on your research for 2-3 months and you must participate in the research symposium in Nashville, TN on August 1-2, 2018 (travel funds provided).
More information: http://medicalstudentdiabetesresearch.org/
Jan. 31- Feb. 3, 2018
2018 Rachmiel Levine-Arthur Riggs Diabetes Research Symposium
Location: Pasadena, CA, USA
More information: https://www.cityofhope.org/research/levine-symposium
Funding opportunities information and deadlines in January, 2018
Jan. 2, 2018
Funding Opportunity Letter of Intent Due Date: Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases
The Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (Catalyst-DEMD) is designed to complement NIDDK's traditional, investigator-in
More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-17-011.html
Jan. 2, 2018
Funding opportunity letter of intent due date: Lymphatics in Health and Disease in the Digestive System
The purpose of this FOA is to invite applications that investigate aspects of lymphatic vessel physiology, development and pathophysiology related to health and diseases of the digestive system. Studies to understand the factors that control local lymphatic vessel functional anatomy and physiology and development during health or disease in this system and its organs, and the mechanisms by which alterations of lymphatic vessel function affect organ function, are of interest. However, studies with the major focus on immune mechanisms, role of lymphatics in cancer metastasis and study of lymphatic vessels in organs other than those from the digestive system will not be considered responsive. Application due date: Feb. 2, 2018.
More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-17-016.html
Funding Opportunity Letter of Intent Due Date: Vanderbilt Digestive Disease Research Center Pilot Project
The Pilot and Feasibility Project Program (P/F) is designed to provide Vanderbilt investigators the opportunity to explore nascent, meritorious hypotheses related to digestive diseases with the ultimate goal being acquisition of external funding. The Vanderbilt Digestive Disease Research Center (VDDRC) plans to fund pilot projects annually. Awards will be made for 1-2 years in duration.
More information: https://ww2.mc.vanderbilt.edu/ddrc/6938
Jan. 13, 2018
Funding Opportunity Letter of Intent Due Date: George M. O'Brien Urology Cooperative Research Centers Program (U54Clinical Trial Optional)
The purpose of this Funding Opportunity Announcement (FOA) is to seek applications for the George M. O’Brien Urology Cooperative Research Centers Program. This program will provide a coordinated platform for multidisciplinaJan. 15, 2018
Funding Opportunity Application Due Date: HIRN New Investigator Pilot Award
The Human Islet Research Network (HIRN) is announcing a competitive New Investigator Pilot Award. The goal of this award is to support a small number of new investigators of exceptional creativity who propose to apply bold and highly innovative new research approaches to biological problems under current investigation in HIRN. The HIRN New Investigator Pilot Award is designed to provide support for early career investigators who may need funding to explore feasibility of a new concept in support of an eventual R01 application. The research proposed must be relevant to the goals of HIRN consortia. Contact the HIRN Coordinating Center (CC) at hirncc@coh.org.Jan. 15, 2018
Funding Opportunity Application Due Date: Vanderbilt Diabetes Center Discovery Program Grant
An individual must be a member of the Vanderbilt or Meharry faculty (Instructor or above) and must fit within NIH Guidelines for eligibility. This P&F support is targeted to any investigator, new or established, proposing to utilize the VICB High-Throughput Screening Facility, BioVU, or the Vanderbilt Mass Spectrometry Research Center Cores to launch new research programs in drug, gene, or biomarker discovery related to diabetes, obesity, or the complications thereof. DRTC P&F grants are intended to provide support for studies that allow an investigator to develop preliminary data sufficient to prepare an application for independent research support through conventional granting mechanisms. This DRTC P&F grant mechanism is intended to support one year of research, although a second year of funding is possible through competitive application. Eligibility: An individual must be a member of the Vanderbilt or Meharry faculty (Instructor or above) and must fit within NIH Guidelines for eligibility.Jan. 15, 2018
Funding Opportunity Application Due Date: Vanderbilt Diabetes Research & Training Center Grant
An individual must be a member of the Vanderbilt or Meharry faculty (Instructor or above) and must fit within NIH Guidelines for eligibility. P&F support is targeted to any investigator, who has not previously received at DRTC P&F award, new or established, from other fields willing to bring their research expertise to diabetes-relevaJan. 23, 2018
Funding opportunity application due date: Diabetic Foot Consortium - Clinical Research Units (U01)
This Funding Opportunity Announcement (FOA) invites applications for Clinical Research Units (CRUs) to form the new Diabetic Foot Consortium (DFC) for multi-site clinical research to validate biomarkers for diabetic foot ulcers that that can predict healing outcomes, guide treatment, and monitor healing and response to treatment. The long-term goal is to lay the foundation for a clinical trial network to test therapies that can improve healing and prevent amputations.Jan. 25, 2018
Funding opportunity application deadline: "Exploration of the Diabetic Foot Ulcer Niche" - Collaborative Pilot Program
The purpose of this Pilot Program is to adapt and evaluate emerging techniques focused on defining cell types and subtypes and their three-dimensionJan. 28, 2018
Funding opportunity letter of intent due date: Developmental Centers for Interdisciplinary Research in Benign Urology (P20 - Clinical Trial Not Allowed)
The purpose of this Funding Opportunity Announcement (FOA) is to seek applications for the Developmental Centers for Interdisciplina
Jan. 30, 2018
Funding opportunity application deadline: Harvard University Digestive Disease Center Pilot And Feasibility Program
The HDDC is focused on the study of epithelial cell function and mucosal biology in inflammation, host defense, and cancer of the gastrointestinaJan. 31, 2018
Diabetes Innovation Challenge Submission Deadline
T1D Exchange and lead sponsors JDRF and The Helmsley Charitable Trust are pleased to announce the 2018 Diabetes Innovation Challenge. 2018 Diabetes Innovation Challenge is offering $250,000 in cash and in-kind Prizes to diabetes innovations!