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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Contaminated
https://web.expasy.org/cellosaurus/CVCL_8262
Organism: Homo sapiens (Human)
Disease: Lung small cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Problematic cell line: Contaminated. Shown to be a SCLC-21H (or SCLC-22H) derivative (PubMed=10508494; PubMed=20143388)..
Proper citation: CLS Cat# 300177, RRID:CVCL_8262 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_2710
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Population: Caucasian., Part of: Human variation panel., Part of: Genetic Testing Reference Material (GeT-RM) samples.
Proper citation: CLS Cat# 300318, RRID:CVCL_2710 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: CLS Cat# 604328, RRID:CVCL_0549 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0059
Organism: Chlorocebus sabaeus (Green monkey)
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.
Proper citation: CLS Cat# 605372, RRID:CVCL_0059 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_S366
Organism: Zalophus californianus (California sealion)
Category: Finite cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: RRID:CVCL_S366 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_S366
Organism: Zalophus californianus (California sealion)
Category: Finite cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: ATCC Cat# CRL-6537, RRID:CVCL_S366 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_S367
Organism: Zalophus californianus (California sealion)
Category: Finite cell line
Comments: Virology: Possibly infected by seal poxvirus., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: RRID:CVCL_S367 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_S331
Organism: Zalophus californianus (California sealion)
Category: Finite cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: ATCC Cat# CRL-6606, RRID:CVCL_S331 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_S331
Organism: Zalophus californianus (California sealion)
Category: Finite cell line
Comments: Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: RRID:CVCL_S331 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_Z243
Organism: Leptinotarsa decemlineata (Colorado potato beetle)
Category: Spontaneously immortalized cell line
Comments: Group: Insect cell line.
Proper citation: ECACC Cat# 93022523, RRID:CVCL_Z243 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_C714
Organism: Mus musculus (Mouse)
Category: Embryonic stem cell
Proper citation: RRID:CVCL_C714 Copy
Possibly Misidentified
https://web.expasy.org/cellosaurus/CVCL_XE04
Organism: Homo sapiens (Human)
Disease: Hilar cholangiocarcinoma
Category: Cancer cell line
Comments: Karyotypic information: Near triploid karyotype (PubMed=31359275)., Population: Chinese., Problematic cell line: Possibly misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (STR profile).., Group: Patented cell line.
Proper citation: RRID:CVCL_XE04 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_Z243
Organism: Leptinotarsa decemlineata (Colorado potato beetle)
Category: Spontaneously immortalized cell line
Comments: Group: Insect cell line.
Proper citation: RRID:CVCL_Z243 Copy
Possibly Contaminated
https://web.expasy.org/cellosaurus/CVCL_B0F2
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Caucasian., Problematic cell line: Probably contaminated. The STR profile is identical to that of the HOS cell line. Originally thought to originate from the lung metastasis of a 12 year old female Chinese osteosarcoma patient.., Group: Patented cell line.
Proper citation: RRID:CVCL_B0F2 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_JY90
Organism: Homo sapiens (Human)
Disease: Invasive breast carcinoma of no special type
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_JY90 Copy
Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_8653
Organism: Mus musculus (Mouse)
Category: Transformed cell line
Comments: Problematic cell line: Misidentified/contaminated. Not from strain BALB/c as originally assigned but from a NIH Swiss strain derivative (PubMed=27844419)..
Proper citation: JCRB Cat# JCRB1355, RRID:CVCL_8653 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_AP65
Organism: Mus musculus (Mouse)
Category: Hybridoma
Proper citation: Coriell Cat# WC00053, RRID:CVCL_AP65 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_J044
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: IZSLER Cat# BS Hy 57, RRID:CVCL_J044 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_J044
Organism: Mus musculus (Mouse)
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: ATCC Cat# HB-8934, RRID:CVCL_J044 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_8071
Organism: Homo sapiens (Human)
Category: Transformed cell line
Proper citation: TKG Cat# TKG 0499, RRID:CVCL_8071 Copy
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