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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_LB32
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter nuclear translocation cell lines co-express a target protein tagged with a beta-galactosidase fragment (Enzyme Donor=ED) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the nucleus. Complementation of the ED and EA enzyme fragments result into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LB32 Copy
https://web.expasy.org/cellosaurus/CVCL_LB17
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LB17 Copy
https://web.expasy.org/cellosaurus/CVCL_LB47
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LB47 Copy
https://web.expasy.org/cellosaurus/CVCL_LB12
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter NHR protein interaction cell lines co-express a NHR tagged with a beta-galactosidase fragment (ProLink=PK) and a receptor co-activator tagged with another fragment (Enzyme Acceptor=EA). Activation of the NHR results in co-activator-EA recruitment thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LB12 Copy
https://web.expasy.org/cellosaurus/CVCL_LB39
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LB39 Copy
https://web.expasy.org/cellosaurus/CVCL_LB46
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LB46 Copy
https://web.expasy.org/cellosaurus/CVCL_IR36
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_IR36 Copy
https://web.expasy.org/cellosaurus/CVCL_R705
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_R705 Copy
https://web.expasy.org/cellosaurus/CVCL_1613
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: JCRB Cat# JCRB0614, RRID:CVCL_1613 Copy
https://web.expasy.org/cellosaurus/CVCL_JX49
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Chinese.
Proper citation: RRID:CVCL_JX49 Copy
https://web.expasy.org/cellosaurus/CVCL_5939
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Proper citation: CLS Cat# 300358, RRID:CVCL_5939 Copy
https://web.expasy.org/cellosaurus/CVCL_B7FK
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Using CRISPR/Cas9D10A NUP96 has been endogenously tagged in both alleles at the C-terminus with mMaple (PubMed=31562488)., Population: Caucasian.
Proper citation: RRID:CVCL_B7FK Copy
https://web.expasy.org/cellosaurus/CVCL_C0QU
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Transfected with a pSBbi-PuroR-ST-PEAK3 that contains a N-terminally Strep-tagged PEAK3., Population: Caucasian.
Proper citation: RRID:CVCL_C0QU Copy
https://web.expasy.org/cellosaurus/CVCL_C0Q8
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Transfected with a pCMV6-AC-HK2-GFP construct that contains HK2 c-terminally tagged with turbo-GFP., Population: Caucasian.
Proper citation: RRID:CVCL_C0Q8 Copy
https://web.expasy.org/cellosaurus/CVCL_B7FM
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Using ZFN NUP107 has been endogenously tagged in both alleles at the N-terminus with a SNAP-tag (PubMed=29630062)., Population: Caucasian.
Proper citation: RRID:CVCL_B7FM Copy
https://web.expasy.org/cellosaurus/CVCL_C0QT
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Transfected with a pBABE-GFP-PEAK3 construct that contains a GFP-PEAK3 fusion (PubMed=34944965)., Population: Caucasian.
Proper citation: RRID:CVCL_C0QT Copy
https://web.expasy.org/cellosaurus/CVCL_B7FI
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Using CRISPR/Cas9D10A NUP96 has been endogenously tagged in both alleles at the C-terminus with a HaloTag (PubMed=31562488)., Population: Caucasian.
Proper citation: RRID:CVCL_B7FI Copy
https://web.expasy.org/cellosaurus/CVCL_C0QG
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Transfected with a Myc.BioID2.13xLinker construct. Control cell line for U2OS-PER2-BioID2 (Cellosaurus=CVCL_C0QF)., Population: Caucasian.
Proper citation: RRID:CVCL_C0QG Copy
https://web.expasy.org/cellosaurus/CVCL_B7FL
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Using CRISPR/Cas9D10A NUP96 has been endogenously tagged in both alleles at the C-terminus with a SNAP-tag (PubMed=31562488)., Population: Caucasian.
Proper citation: RRID:CVCL_B7FL Copy
https://web.expasy.org/cellosaurus/CVCL_C0BP
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: RRID:CVCL_C0BP Copy
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