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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Discontinued
https://web.expasy.org/cellosaurus/CVCL_6472
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: D13S317., Population: Caucasian., Part of: Wistar Institute melanoma cell line collection., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_6472 Copy
Possibly Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_8787
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: D18S51., Population: Caucasian., Part of: Wistar Institute melanoma cell line collection., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_8787 Copy
Possibly Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_A424
Organism: Homo sapiens (Human)
Disease: Pancreatic adenocarcinoma
Category: Cancer cell line
Comments: From: Scott and White Clinic; Temple; USA., Part of: UBC-40 urothelial bladder cancer cell line index., Problematic cell line: Possibly misidentified/contaminated. Reported by PubMed=11787853 to contain the same HPV18 sequences as the cervix carcinoma cell line C-4-I (Cellosaurus=CVCL_2253) and to lack mutations in KRAS, TP53, CDKN2A and DPC4 often found in pancreatic adenocarcinoma. Considered by PubMed=25997541 to be a bladder carcinoma cell line..
Proper citation: RRID:CVCL_A424 Copy
https://web.expasy.org/cellosaurus/CVCL_8800
Organism: Homo sapiens (Human)
Disease: Diffuse large B-cell lymphoma activated B-cell type
Category: Cancer cell line
Comments: Caution: A cell line, now termed GNE-587170 (Cellosaurus=CVCL_AT69), was mistakenly distributed by OCI to a number of groups under the designation OCI-Ly-3, the origin of that cell line is now known., Population: Caucasian., From: Ontario Cancer Institute (OCI); Toronto; Canada., Part of: MD Anderson Cell Lines Project., Part of: LL-100 blood cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_8800 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_2787
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Caution: FLC-4 (Cellosaurus=CVCL_D204) is often stated to be synonymous with JHH-4, but a FLC-4 patent reference (Patent=US5804441) seems to indicate that it is derived from JHH-4 and has a different karyotype., Population: Japanese., Part of: MD Anderson Cell Lines Project., Part of: Liver Cancer Model Repository (LIMORE)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_2787 Copy
Possibly Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_6357
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: CSF1PO., Characteristics: Metastatic. Established from the lung of a nude mouse after 4 sequential passages of the parent cell line (PubMed=2156614)., Population: Caucasian., Part of: Wistar Institute melanoma cell line collection., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_6357 Copy
Misidentified Discontinued
https://web.expasy.org/cellosaurus/CVCL_0022
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Misidentified. This cell line is not the original glioblastoma cell line established in 1968 at the University of Uppsala. As described in PubMed=27582061 it is most probably also a glioblastoma cell line but whose origin is unknow. See U-87MG Uppsala (Cellosaurus=CVCL_GP63) for the original U-87MG cell line..
Proper citation: RRID:CVCL_0022 Copy
Partially Contaminated Possibly Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_5239
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: Amelogenin., Characteristics: Established from serial passaging of the parent cell line through immune deficient mice and harvesting lung metastasis., Population: Caucasian., Part of: Wistar Institute melanoma cell line collection., Problematic cell line: Partially contaminated. The stock formerly distributed by Coriell (WC00058) contains a significant amount of mouse DNA (DOI=10.4172/1948-5956.1000196). This is not the case of the original Wistar stock which was distributed by Rockland (DOI=10.4172/1948-5956.1000401)..
Proper citation: RRID:CVCL_5239 Copy
https://web.expasy.org/cellosaurus/CVCL_E8AV
Organism: Homo sapiens (Human)
Disease: Childhood T acute lymphoblastic leukemia
Category: Cancer cell line
Comments: Virology: Susceptible to infection by CXCR4-tropic HIV-1 strains (example HXB2) (PubMed=17182760)., Virology: Infected with Moloney murine leukemia virus (MoMuLV) from MiCl1 (S+L-) (Cellosaurus=CVCL_3405) cells (from parent cell line HPB-Ma)., Characteristics: Transfected with two constructs. 1) 53LTRN-lucneoR#1 which contains the HIV-1 strain HXB2 LTR driving the expression of a Luc-DsRed fusion protein. This allows HIV-1 replication to be quantitatively evaluated by using luciferase activity when the LTR is activated by Tat, and the DsRed gene allows HIV-1 infected cells to be identified by red fluorescence. 2) pRenillaPac where Renilla luciferase is under the control of a CMV promoter and is used to monitor cell numbers and viability (PubMed=17182760)., Characteristics: Reporter cell line to measure HIV-1 infectivity and thus evaluate susceptibility to anti-HIV-1 drugs (PubMed=17182760)., Population: Japanese.
Proper citation: RRID:CVCL_E8AV Copy
https://web.expasy.org/cellosaurus/CVCL_E8AW
Organism: Homo sapiens (Human)
Disease: Childhood T acute lymphoblastic leukemia
Category: Cancer cell line
Comments: Virology: Susceptible to infection by both CCR5-tropic (example JRCSF) and CXCR4-tropic HIV-1 strains (PubMed=17182760)., Virology: Infected with Moloney murine leukemia virus (MoMuLV) from MiCl1 (S+L-) (Cellosaurus=CVCL_3405) cells (from parent cell line X4-MaRBLE)., Characteristics: Transfected with three constructs. 1) 53LTRN-lucneoR#1 which contains the HIV-1 strain HXB2 LTR driving the expression of a Luc-DsRed fusion protein. This allows HIV-1 replication to be quantitatively evaluated by using luciferase activity when the LTR is activated by Tat, and the DsRed gene allows HIV-1 infected cells to be identified by red fluorescence. 2) pRenillaPac where Renilla luciferase is under the control of a CMV promoter and is used to monitor cell numbers and viability, 3) pCCR5/CEP4 which contains CCR5 under the control of a CMV promoter (PubMed=17182760)., Characteristics: Reporter cell line to measure HIV-1 infectivity and thus evaluate susceptibility to anti-HIV-1 drugs (PubMed=17182760)., Population: Japanese.
Proper citation: RRID:CVCL_E8AW Copy
https://web.expasy.org/cellosaurus/CVCL_C615
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Proper citation: RRID:CVCL_C615 Copy
https://web.expasy.org/cellosaurus/CVCL_A4VI
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Population: Caucasian., From: Department of Biomedical Research, Foundation of Research and Technology-Hellas; Ioannina; Greece.
Proper citation: RRID:CVCL_A4VI Copy
https://web.expasy.org/cellosaurus/CVCL_C603
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Proper citation: RRID:CVCL_C603 Copy
https://web.expasy.org/cellosaurus/CVCL_C581
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Proper citation: RRID:CVCL_C581 Copy
https://web.expasy.org/cellosaurus/CVCL_M960
Organism: Homo sapiens (Human)
Category: Telomerase immortalized cell line
Proper citation: RRID:CVCL_M960 Copy
https://web.expasy.org/cellosaurus/CVCL_9678
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Proper citation: RRID:CVCL_9678 Copy
https://web.expasy.org/cellosaurus/CVCL_5752
Organism: Homo sapiens (Human)
Category: Finite cell line
Proper citation: RRID:CVCL_5752 Copy
https://web.expasy.org/cellosaurus/CVCL_A4VJ
Organism: Homo sapiens (Human)
Category: Induced pluripotent stem cell
Comments: Population: Caucasian., From: Department of Biomedical Research, Foundation of Research and Technology-Hellas; Ioannina; Greece.
Proper citation: RRID:CVCL_A4VJ Copy
https://web.expasy.org/cellosaurus/CVCL_9677
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Proper citation: RRID:CVCL_9677 Copy
https://web.expasy.org/cellosaurus/CVCL_S615
Organism: Homo sapiens (Human)
Disease: Unilateral retinoblastoma
Category: Cancer cell line
Proper citation: RRID:CVCL_S615 Copy
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