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URL: https://web.expasy.org/cellosaurus/CVCL_D1FC
Proper Citation: WiCell Cat# hipsc-di21-c2-4-2, RRID:CVCL_D1FC
Description: Cell line hIPSC-Di21-C2-4-3 is a Induced pluripotent stem cell with a species of origin Homo sapiens (Human)
Sex: Female
Disease: Down syndrome
Defining Citation: PMID:23084023
Comments: Characteristics: This cell line has lot one copy of chromosome 21. Using CRISPR/Cas9 a IRES-TK-Neo-polyA site cassette was introduced in one allele of exon 3 of APP on chromosome 21 of the parent cell line. The parent cell line was cultured in the absence of G418 selection for three passages to allow chromosome loss to take place, and then were cultured in the presence of ganciclovir (GCV) to select a clone without the presence of the TK-neo construct (PubMed=23084023)., Population: Caucasian.
Category: Induced pluripotent stem cell
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Source: Cellosaurus
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