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URL: https://web.expasy.org/cellosaurus/CVCL_6571
Proper Citation: RRID:CVCL_6571
Description: Cell line VM7Luc4E2 is a Cancer cell line with a species of origin Homo sapiens (Human)
Sex: Female
Disease: Invasive breast carcinoma of no special type
Defining Citation: PMID:10900408, PMID:26139245
Comments: Characteristics: Acts through the activation of a luciferase reporter gene under the control of estrogen response elements (EREs) upstream of the mouse mammary tumor viral (MMTV) promoter., Characteristics: Emits measurable light in response to estrogen and estrogen-like substances. Used for identifying estrogen receptor agonists and antagonists., Biotechnology: Used in the Organisation for Economic Co-operation and Development (OECD) detection of estrogenic/antiestrogenic chemicals test method 457 (DOI=10.1787/9789264185395-en)., Biotechnology: Cell line developed for VM7Luc ER TA (VM7Luc Estrogen Receptor TransActivation) bioassay which was formerly known as BG1Luc ER TA (BG1Luc Estrogen Receptor TransActivation)., Population: Caucasian., Problematic cell line: Contaminated. Shown to be a MCF-7 derivative (EURL ECVAM-TSAR=TM2016-09). Originally thought to be a BG1 (Cellosaurus=CVCL_6570) derivative..
Category: Cancer cell line
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Source: Cellosaurus
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