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URL: https://web.expasy.org/cellosaurus/CVCL_1068
Proper Citation: RRID:CVCL_1068
Description: Cell line ACN is a Cancer cell line with a species of origin Homo sapiens (Human)
Sex: Sex unspecified
Disease: Melanoma
Defining Citation: PMID:1354203, PMID:2467885, PMID:8509230, PMID:15150552, PMID:20164919, PMID:30894373
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Probably contaminated. The STR profile of ACN and LN-464 are identical. SNP analysis (DepMap) also shows identity of both cell lines. We believe this is a melanoma cell line based on the presence of the BRAF V600E mutation as well as the RNASeq expression profile of LN-464 (DepMap) which clusters with that of melanoma patient samples. Originally thought to originate from the bone marrow of a 36-month old boy with a metastatic adrenal stage-IV neuroblastoma..
Category: Cancer cell line
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Source: Cellosaurus
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