dkNET Webinar "The Mammalian Adipose Tissue Knowledge Portal (MATKP): An Open Community Portal for Multi-Species Adipose Biology"

Join dkNET Webinar on Friday, February 27, 2026, 11 am - 12 pm PT

Presenter: Julie Jurgens, PhD, The Broad Institute of MIT and Harvard

Abstract

The Mammalian Adipose Tissue Knowledge Portal (MATKP; https://matkp.org/) is an open-access, community-driven resource designed to accelerate discovery in mammalian adipose biology. MATKP integrates multi-species datasets across a range of adipose tissue depots and cell types, with an initial focus on human and mouse transcriptomic datasets. The portal currently provides bulk, pseudobulk, single-cell, and single-nucleus RNA sequencing data alongside interactive visualization tools, including a Single Cell Browser and Differential Gene Expression Browser. MATKP harmonizes datasets using standardized ontologies to enable cross-study interoperability and integrates genetic association results, functional annotations, and pathway enrichment analyses to connect molecular data with metabolic disease phenotypes. The platform also features a public Data Registry to support community data submission. This webinar will introduce the latest updates to the MATKP, including expanded mouse datasets, interactive features to explore the adipogenesis process, and inferred gene programs across adipose tissue cell types.

The top 3 key questions that the MATKP can answer:

1. How do specific genes influence adipose tissue biology and related metabolic phenotypes?

2. Which adipose tissue signatures, pathways, and gene programs are associated with metabolic disease phenotypes?

3. How do cell type-specific expression patterns contribute to disease mechanisms?

Dial-in Information: https://uchealth.zoom.us/webinar/register/WN_vSra3PQzQHCPMTeFJnul0w

Date/Time: Friday, February 27, 2026, 11 am - 12 pm PT

Upcoming webinars schedule: https://dknet.org/about/webinar