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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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S-H3.3+GFP/H3.2-8 Resource Report Resource Website |
RRID:TSC_SD01896 | Tetrahymena thermophila | Somatic replace HHT2 coding region with HHT3-GFP sequence. Not sure where the neo2 cassette is. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTT3 (TTHERM_00016170) | Macronucleus: C-terminal GFP-tag of HHT3, not sure if complete replacement, into HHT2 locus | SD01896 | mpr1-1/mpr1-1 (?HHT2/hht2[3’neo2 ∆::(HHT3,GFPc)]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 | 2026-08-29 04:08:55 | 0 | ||||
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TWI11 s KO (8) 9-1 Resource Report Resource Website |
RRID:TSC_SD02865 | Tetrahymena thermophila | Somatic TWI 11 KO. Part of the coding sequence was replaced by neo3. In CU428 From the Gorovsky lab, University of Rochester. | TWI11 (TTHERM_00144830) | Macronucleus: TWI11 with neo3 | SD02865 | mpr1-1/mpr1-1 (twi11[∆?::neo3]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:55 | 0 | |||||
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HTB1-B4a Resource Report Resource Website |
RRID:TSC_SD02468 | Tetrahymena thermophila | New batch, rescue of progeny h∆∆HTB86B4A6 and D2A2. Not mating type II,VI,VII. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180) | Micronucleus: neo2 into coding of HTB1 and HTB2 Macronucleus: HTB1 | SD02468 | htb1[∆::neo2]/htb1[∆::neo2]; htb2 [∆::neo2]/htb2 [∆::neo2] (HTB1/htb1[∆::neo2]; htb2 [∆::neo2] assorted to pm-s so must have lost neo2; mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2026-08-29 04:08:54 | 0 | ||||
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S-H3.3+GFP/H3.3-75 Resource Report Resource Website |
RRID:TSC_SD01897 | Tetrahymena thermophila | Somatic replace HHT3 gene with HHT3-GFP sequence. Neo2 in 5’ flanking of HHT3. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTT3 (TTHERM_00016170) | Macronucleus: C-terminal GFP- tag of HHT3, not sure if complete replacement | SD01897 | mpr1-1/mpr1-1 (?HHT3/hht3[5’neo2,GFPc]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 | 2026-08-29 04:08:55 | 0 | ||||
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BMCG-hy3-63 Resource Report Resource Website |
RRID:TSC_SD01813 | Tetrahymena thermophila | major h3, h4 germline KO cells were rescued with hy3. Hybrid H3 contruct with H3(1-75) H3.3 (76-90) H3 (91-135), then transformed with Bsr-mtt1-cna1-gfp construct. CNA1-GFP seq. was used to replace MTT1 coding seq. Bsr1 cas. Thaw cells without drugs, then grow them in 60-100ug/ml blasticidin, Use 0.5-1 ug/ml cadmium chloride to express and see the green centromere. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | CNA1 (TTHERM_00146340), HHT2 (TTHERM_00189180), HHT3 (TTHERM_00016170) | Micronucleus: ∆hht1, ∆hht2 ∆hhf1, ∆hhf2 Macronucleus: hybrid H3 replaces major H3. In MTT1 locus, GFP tagged CNA1 | SD01813 | ∆hht1 & ∆hht2 ∆hhf1 ∆hhf2 hht1[∆,neo2]/hht1[∆,neo2]; hhf1[∆,neo]/hhf1[∆,neo]; hhf2,hht2[∆, neo2]/ hhf2,hht2[∆, neo2] (hht1[∆,neo2]/hhf1[∆,neo]/hhf2,hht2[∆, neo2]/ chimeric H3[H3(1-75) H3.3(76-90) H3(91-135)] MTT1/mtt1-?[5’ neo2,∆,(::CNA1), GFPc]; pm-r, bsr-1, hybrid H3 replaces major H3. In MTT1 locus,GFP tagged CNA1) | TSC, Tetrahymena Stock Center | TSC | PMID:15701804 | 2026-08-29 04:08:55 | 0 | ||||
|
SB2429H Resource Report Resource Website |
RRID:TSC_SD01265 | Tetrahymena thermophila | This strain must be crossed to A* for two rounds and cy-r progeny selected to generate the meiotic segregant panel member which is cy-r, mp-s, pm-s, mat3. Submitted by Eduardo Orias, University of California, Santa Barbara | SD01265 | chx1-1/chx1-1; MPR1[C3]/MPR1[C3]; PMR1[C3]PMR1[C3]; MAT3/MAT3 (CHX1[C3]; cy-s, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:8601476 PMID:8725229 |
2026-08-29 04:08:55 | 0 | ||||||
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SB4200 Resource Report Resource Website |
RRID:TSC_SD01540 | Tetrahymena thermophila | Submitted by Eduardo Orias, University of California, Santa Barbara | SD01540 | pmr1[C3]-1/pmr1[C3]-1;CHX1[C3]/CHX1[C3] (PMR1/PMR1 ;chx1-1/chx1-1; cy-r, pm-s, VII) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:55 | 0 | |||||||
|
B-D4-V5-PP36 Resource Report Resource Website |
RRID:TSC_SD02233 | Tetrahymena thermophila | somatic mac transformation of B2086 with construct of PP36 (Protein phosphatase 36 kD MW, predicted TTHERM_00238830) V5 tag after ATG, with neo3 in reverse orientation -200 bases upstream of ATG. Localizes to nucleoli, not studied further. Incomplete replacement, pushed to 3mg/ml pm with 0.5ug/ml Cd. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | TTHERM_00238830 | Macronucleus: V5 tagged PP36 protein | SD02233 | (pm-r, II) | TSC, Tetrahymena Stock Center | TSC | PMID:22426537 | 2026-08-29 04:08:55 | 0 | ||||
|
B1KO-4 Resource Report Resource Website |
RRID:TSC_SD02753 | Tetrahymena thermophila | Heterozygous germline transformant of BTUI knockout. Derived from Cu428 X B2086 transformed w/ BHAB-1(construct). When crossed to CU427, gave cyr and pmr progeny. Can mate to BIKO-2. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | BTU1 (TTHERM_00348510) | Micronucleus: H4-neo replaces coding of BTU1, heterozygous | SD02753 | BTU1/btu1[∆,::H4-neo]; MPR1-1/mpr1-1 | TSC, Tetrahymena Stock Center | TSC | PMID:9037049 PMID:10831613 |
2026-08-29 04:08:55 | 0 | ||||
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BHM-1 Resource Report Resource Website |
RRID:TSC_SD02236 | Tetrahymena thermophila | Progeny of DB6B x DB2A, transformed by BTU-HA TTMet construct. The transformants are dependent on Cadmium, 0.25ug/ml. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | BTU1 (TTHERM_00348510), BTU2 (TTHERM_00836580) | Micronucleus: knockout of btu1 with neo knockout of btu2 with bsr Macronucleus: HA c-terminal tagged BTU1 into MTT1 locus | SD02236 | btu1-?[∆::neo1]/ btu1-?[∆::neo1]; btu2-?[∆::bsr1]/ btu2-?[∆::bsr1]; CHX1/CHX1; mpr1-1/mpr1-1 or MPR1/MPR1 (btu2-?[∆::bsr1]; btu1-?[∆::neo1]; MTT1/mtt1-?[∆(::BTU1)HAc]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:15254268 PMID:11864572 PMID:10831613 |
2026-08-29 04:08:55 | 0 | ||||
|
RDP1-T1 Resource Report Resource Website |
RRID:TSC_SD02512 | Tetrahymena thermophila | Shot plasmid pRDP1::TAG-neo3 #110 into conjugating CU428XB2086 but only got somatic strains, slow growth. No other information From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | RDR1 (TTHERM_00853150) | Macronucleus: HA-FLAG tag of RDR1 | SD02512 | (pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:55 | 0 | |||||
|
UCB305 Resource Report Resource Website |
RRID:TSC_SD03298 | Tetrahymena thermophila | sfr13 complete null rescue. First a 5' part of the gene was introduced into the sfr13 locus with BSR selection that included a 5'FLAG tag. Second, the remainder of the gene was introduced to the KO locus with the 5' BSR insertion, and rescue of the small cell size phenotype was selected for. From the Winey Lab at the University of Colorado Boulder. | SFR13 (TTHERM_00522830) | Micronucleus: cen2-1[∆::NEO2] Macronucleus: FLAG-SFR13 rescue in two parts (see comments) | SD03298 | sfr13-1[∆::NEO2] (sfr13-1[∆::NEO2]::SFR13[5'FLAG::BSR]::SFR13 3'; WT cell size and number of basal bodies., ?) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:55 | 0 | |||||
|
NgoA KO-12 Resource Report Resource Website |
RRID:TSC_SD02488 | Tetrahymena thermophila | It’s a homozygous clone of KO of NgoA gene in both mac and mic grew up from sinle cell. the KO construct is: Neo gene driven by MTT promoter(2.5kb), and this is in opposite direction in NgoA flanking. NgoA KO-12 can mate with NgoA KO-7 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | NgoA (TTHERM_00655890) | Micronucleus: neo3 into NgoA coding Macronucleus: neo3 into NgoA coding | SD02488 | ngoA[∆::neo3]/ngoA[∆::neo3] (ngoA[∆::neo3] ; pm-r, NgoA KO, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:15870266 | 2026-08-29 04:08:55 | 0 | ||||
|
CNB KO F2-1-13 (1) Resource Report Resource Website |
RRID:TSC_SD02761 | Tetrahymena thermophila | Homozygote CnjB KO Homokaryon. Partial cnjB coding sequences were replaced by neo3. This strain was supposed to be pm-r but thawed pm-s. From the Gorovsky lab, University of Rochester. | CnjB (TTHERM_01091290) | Micronucleus: Neo3 replaces part of coding Macronucleus: Neo3 replaces part of coding | SD02761 | cnjB[∆?::neo3]/ cnjB[∆?::neo3] (cnjB[∆?::neo3], ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19596782 | 2026-08-29 04:08:55 | 0 | ||||
|
double eri1+ twi1 5’ neo B1 Resource Report Resource Website |
RRID:TSC_SD02007 | Tetrahymena thermophila | Eri1 KO construct was shot into twi1 KO homozygous homokaryon (Neo3 gene is lost in mac, strain is pm-s). From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | ERI1 (TTHERM_00501020) | Micronucleus: TWI1 ko Macronucleus: twi1 kO and ERI1 KO | SD02007 | twi1[∆?::neo3]/twi1[∆?::neo3] (twi1[∆?::neo3]; eri1[∆?::neo3]; same as ∆Twi1) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:55 | 0 | |||||
|
19882-2 Resource Report Resource Website |
RRID:TSC_SD01556 | Tetrahymena thermophila | Collected by Paul Doerder on 8/26/2008 from the pond designated SG69-1 in Guys Mills, PA (lat. 41 37.174, long. -79 55.095, elevation 1549 ft, nearest road is Carpenter Road). Geographical area: Western Pennsylvania Collection number: 893 Has a micronucleus. Cech's self-splicing intron is present. Cytochrome oxidase I haplotype = ANF1 | SD01556 | (VI) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:54 | 0 | |||||||
|
∆H3 gl 2.2 Resource Report Resource Website |
RRID:TSC_SD01955 | Tetrahymena thermophila | This is the germline KO homozygous heterokaryon. Both copies of major histone H3 were removed. Also HHF2 and intergenic region connecting it to HHT2. KO with Neo cassette. The ∆H3 gl 2.* series have a different mating type from the ∆H3 gl 10.* series. From the Gorovsky lab, University of Rochester. | HHT2 (TTHERM_00189180), HHF2 (TTHERM_00189170) | Micronucleus: Neo2 ko of HHT1 and HHT2/HHF2 | SD01955 | hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; mpr1-1/mpr1-1 (mpr1-1; mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 | 2026-08-29 04:08:55 | 0 | ||||
|
ATU-4D Resource Report Resource Website |
RRID:TSC_SD01837 | Tetrahymena thermophila | It is a progeny of conjugants of AAK02.7XAAKO5.5 transformed with pATU-4D derived from pTUB100E3-PvuII (linearized)where the ATU1 gene is marked with Hae III and Pvu II sites and E443D, E445D,E446D,E447D From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | ATU1 (TTHERM_00558620) | Micronucleus: neo replaces ATU1 coding Macronucleus: ATU1 with E443D, E445D, E446D, E447D or neo replacing coding of some ATU1 genes | SD01837 | atu1-1[Δ::neo1]/atu1-1[Δ::neo1]; mpr1-1/mpr1-1 or MPR1/MPR1 (atu1-1[Δ::neo1]/atu1[E443D,E445D E446D,E447D]; ATU1 with E443D, E445D,E446D,E447D or neo replacing coding of some ATU1 genes, pm-r, cy-s,mp-? ) | TSC, Tetrahymena Stock Center | TSC | PMID:10831613 PMID:9037049 |
2026-08-29 04:08:54 | 0 | ||||
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BLTGL5-1 Resource Report Resource Website |
RRID:TSC_SD02250 | Tetrahymena thermophila | BLT germline heterokaryon, homozyous KO in mic, pm sensitive (120 ug/ml). Cd induced Neo cassette (1.2 ug/ml)--MTT promoter, Neo coding, BTU2 terminator. Construct pBLTMKO, Mates with BLTGL1-3,4,5 and 2-5. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | BLT1 (TTHERM_01104960) | Micronucleus: Neo3 replaces BLT coding | SD02250 | blt1-1[∆,neo3]/ blt1-1[∆,neo3]; MPR1-?/ MPR1-? (BLT1; mpr1-1; mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:54 | 0 | |||||
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CU5041 Resource Report Resource Website |
RRID:TSC_SD01166 | Tetrahymena thermophila | SD01166 | chx1-1/chx1-1; pmr1-1/pmr1-1; Del 5 (CHX1; pmr1-1; cy-s, pm-r, II) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:54 | 0 |
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