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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00024068
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: ckSi26 I; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:KW2206, CGC_KW2206
Notes: ckSi26 [cdk-12::GFP::pal-1 3'UTR + unc-119(+)] I. GFP is expressed in all somatic nuclei; expressed in germline only at end of oogenesis. Reference: Bowman EA, et al. Development. (In Press).|"ckSi26 [cdk-12::GFP::pal-1 3UTR + unc-119(+)] I. GFP is expressed in all somatic nuclei; expressed in germline only at end of oogenesis. Reference: Bowman EA, et al. Development. (In Press)."
Proper citation: RRID:WB-STRAIN:WBStrain00024068 Copy
http://www.wormbase.org/db/get?name=WBStrain00024101
Source Database: WormBase (WB)
Affected Genes: WBGene00003831(nuo-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00003831(nuo-1), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: nuo-1(ua1) II; unc-119(ed3) III; uaEx27.
Alternate IDs: WB-STRAIN:LB27, CGC_LB27
Notes: uaEx27 [(p016bA443F) nuo-1(+) + unc-119(+)]. Contains an extrachromosomal array carrying nuo-1(A443F) in a plasmid derived from pDP#MM016b. Complements both nuo-1(ua1) and unc-119(ed3). Generated via microparticle bombardment, therefore, most likely low-copy expression of transgene. Low brood size. Short life span. Sensitive to oxidative stress.
Proper citation: RRID:WB-STRAIN:WBStrain00024101 Copy
http://www.wormbase.org/db/get?name=WBStrain00024065
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: ckSi21 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:KW2196, CGC_KW2196
Notes: ckSi21 [cdk-9::GFP::pal-1 3'UTR + unc-119(+)] II. GFP is expressed in all somatic nuclei; expressed in germline only at end of oogenesis. Reference: Bowman EA, et al. Development. (In Press).|"ckSi21 [cdk-9::GFP::pal-1 3UTR + unc-119(+)] II. GFP is expressed in all somatic nuclei; expressed in germline only at end of oogenesis. Reference: Bowman EA, et al. Development. (In Press)."
Proper citation: RRID:WB-STRAIN:WBStrain00024065 Copy
http://www.wormbase.org/db/get?name=WBStrain00024062
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: ckSi6 I; ckSi4 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:KW2185, CGC_KW2185
Notes: ckSi6 [cdk-12::GFP + unc-119(+)] I. ckSi6 rescues cdk-12(tm3846). ckSi4 [cdk-9::mCherry + unc-119(+)] II. ckSi4 rescues cdk-9(tm2884). GFP and mCherry is expressed in all nuclei. Reference: Bowman EA, et al. Development. (In Press).
Proper citation: RRID:WB-STRAIN:WBStrain00024062 Copy
http://www.wormbase.org/db/get?name=WBStrain00024057
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: ckSi9 I; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:KW2157, CGC_KW2157
Notes: ckSi9 [cdk-12(D462N)::GFP + unc-119(+)] I. Reference: Bowman EA, et al. Development. (In Press).
Proper citation: RRID:WB-STRAIN:WBStrain00024057 Copy
http://www.wormbase.org/db/get?name=WBStrain00024058
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: ckSi12 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:KW2159, CGC_KW2159
Notes: ckSi12 [cdk-9(D235N)::mCherry + unc-119(+)] II. Reference: Bowman EA, et al. Development. (In Press).
Proper citation: RRID:WB-STRAIN:WBStrain00024058 Copy
http://www.wormbase.org/db/get?name=WBStrain00024056
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: ckSi15 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:KW2147, CGC_KW2147
Notes: ckSi15 [ccnk-1::GFP + unc-119(+)] II. Reference: Bowman EA, et al. Development. (In Press).
Proper citation: RRID:WB-STRAIN:WBStrain00024056 Copy
http://www.wormbase.org/db/get?name=WBStrain00024059
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: ckSi13 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:KW2167, CGC_KW2167
Notes: ckSi13 [cdk-9::GFP + unc-119(+)] II. Reference: Bowman EA, et al. Development. (In Press).
Proper citation: RRID:WB-STRAIN:WBStrain00024059 Copy
http://www.wormbase.org/db/get?name=WBStrain00024102
Source Database: WormBase (WB)
Affected Genes: WBGene00003831(nuo-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00003831(nuo-1), WBGene00006843(unc-119)
Availability: unknown
Source References: EMPTY
Synonyms: nuo-1(ua1)/+ IV;unc-119(ed3) II.
Alternate IDs: WB-STRAIN:LB77
Notes: LB77 [nuo-1(ua1)/+], also homozygous for the unc-119(ed3. Renders the animals partially paralyzed and unable to form dauer larvae.
Proper citation: RRID:WB-STRAIN:WBStrain00024102 Copy
http://www.wormbase.org/db/get?name=WBStrain00024210
Source Database: WormBase (WB)
Affected Genes: WBGene00000491(che-12)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00000491(che-12), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; che-12(cp25[che-12::GFP + LoxP + unc-119(+) + LoxP]) V.
Alternate IDs: WB-STRAIN:LP176, CGC_LP176
Notes: Made_by: Alka Das & Dan Dickinson|"N-terminally tagged GFP::CHE-12. Cilia are slightly shorter than WT. GFP fluorescence appears in multiple sensory cilia in the head and phasmid neuron cilia in the tail. Reference: Das A, et al. Mol Biol Cell. 2015 Nov 15;26(23):4248-64."
Proper citation: RRID:WB-STRAIN:WBStrain00024210 Copy
http://www.wormbase.org/db/get?name=WBStrain00024214
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: cpIs56 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:LP193, CGC_LP193
Notes: cpIs56 [mex-5p::TagRFP-T::PLC(delta)-PH::tbb-2 3'UTR + unc-119 (+)] II. Reporter labels plasma membrane in early embryo. Transgene construct consisted of a germline promoter sequence (mex-5) driving the expression of a fluorescent protein fused to the N-terminus of the the pleckstrin homology domain from phospholipase C-(delta)1 (PH domain) and a 2x Flag epitope tag. Reference: Heppert JK, et al. Mol Biol Cell. 2016 Nov 7;27(22):3385-3394.|"Made_by: Chris Higgins"
Proper citation: RRID:WB-STRAIN:WBStrain00024214 Copy
http://www.wormbase.org/db/get?name=WBStrain00026463
Source Database: WormBase (WB)
Affected Genes: WBGene00003183(mei-1)|WBGene00006752(unc-13)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00003183(mei-1), WBGene00006752(unc-13), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: mei-1(ct46) unc-13(e1091) I; unc-119(ed3) III; abcIs3.
Alternate IDs: WB-STRAIN:MAS94, CGC_MAS94
Notes: abcIs3 [pie-1p::ebp-2::GFP + unc-119(+)]. Embryonic-lethal at 25C due to dominant gain-of-function mutation mei-1(ct46), and Uncoordinated due to unc-13 mutation. Maternal expression of EBP-2::GFP microtubule end-binding protein. EBP-2 encodes an EB1-like protein (end-binding) that, in early embryos, locates to the growing tips of microtubules. A strong fluorescent signal localizes to the centrosomes of early embryos due to a high concentration of polymerizing microtubules. mei-1(ct46)-based ectopic microtubule severing causes mitotic spindle defects in the early embryo. References: Gusnowski EM, Srayko M. J Cell Biol. 2011 Aug 8;194(3):377-86. Tegha-Dunghu J, et al. Methods Mol Biol. 2014;1136:103-16.
Proper citation: RRID:WB-STRAIN:WBStrain00026463 Copy
http://www.wormbase.org/db/get?name=WBStrain00026462
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; abcIs3.
Alternate IDs: WB-STRAIN:MAS37, CGC_MAS37
Notes: abcIs3 [pie-1p::ebp-2::GFP + unc-119(+)]. Superficially wild-type. Maternal expression of EBP-2::GFP microtubule end-binding protein. In early embryos, EBP-2 encodes an EB1-like protein (end-binding) that locates to the growing tips of microtubules (not detected on depolymerizing microtubules). A strong fluorescent signal localizes to the centrosome due to high concentration of polymerizing microtubule ends. References: Gusnowski EM, Srayko M. J Cell Biol. 2011 Aug 8;194(3):377-86. Tegha-Dunghu J, et al. Methods Mol Biol. 2014;1136:103-16.
Proper citation: RRID:WB-STRAIN:WBStrain00026462 Copy
http://www.wormbase.org/db/get?name=WBStrain00026429
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; dqIs3.
Alternate IDs: WB-STRAIN:MAD3, CGC_MAD3
Notes: dqIs3 [pie-1p::dyn1B::GFP + unc-119(+)]. Grow at 25 degrees.|"Made_by: Y. Nakayama/D. Poole"
Proper citation: RRID:WB-STRAIN:WBStrain00026429 Copy
http://www.wormbase.org/db/get?name=WBStrain00026598
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00077726(mir-1820)
Genomic Alteration: WBGene00006843(unc-119), WBGene00077726(mir-1820)
Availability: available
Source References: EMPTY
Synonyms: ttTi5606 II; unc-119(ed3) III; mir-1820(luc16[unc-119(+)]) IV.
Alternate IDs: WB-STRAIN:MLC349, CGC_MLC349
Notes: Superficially wild-type. CRISPR/Cas9-engineered mir-1820 deletion allele; miRNA hairpin replaced by unc-119.
Proper citation: RRID:WB-STRAIN:WBStrain00026598 Copy
http://www.wormbase.org/db/get?name=WBStrain00027619
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00011887(set-17)
Genomic Alteration: WBGene00006843(unc-119), WBGene00011887(set-17)
Availability: available
Source References: EMPTY
Synonyms: set-17(n5017) II ; unc-119(ed3) III ; nSi3 IV
Alternate IDs: WB-STRAIN:MT21478, CGC_MT21478
Notes: Mutagen:MOS Transposase|"nSi3 [set-17p::set-17(+)::GFP::set-17 3UTR + unc-119(+)] IV. nSi3 expresses a translational fusion of genomic set-17 and GFP. nSi3 rescues the brood size defect of n5017 in this strain. nSi3 is a single copy MOS-mediated transposition into the cxTi10882 site; GFP detectable in the nuclei of the hypoderm, sperm and proximal germline, as well as some other cells. Reference: Engert CG, et al. PLoS Genet. 2018 Apr 27;14(4):e1007295."
Proper citation: RRID:WB-STRAIN:WBStrain00027619 Copy
http://www.wormbase.org/db/get?name=WBStrain00028870
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed4) III; qyEx114.
Alternate IDs: WB-STRAIN:NK773, CGC_NK773
Notes: qyEx114 [C28C12.10::GFP + unc-119(+)]. Maintain by picking non-Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00028870 Copy
http://www.wormbase.org/db/get?name=WBStrain00028871
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37756590
Synonyms: unc-119(ed4) III; qyEx116.
Alternate IDs: WB-STRAIN:NK774, CGC_NK774
Notes: qyEx116 [C14A11.3b::GFP + unc-119(+)]. Maintain by picking non-Unc.|"Supplementary_genotype qyEx116 [pcgef-1b::GFP + unc-119(+)]"
Proper citation: RRID:WB-STRAIN:WBStrain00028871 Copy
http://www.wormbase.org/db/get?name=WBStrain00028872
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37756590
Synonyms: unc-119(ed4) III; qyEx117.
Alternate IDs: WB-STRAIN:NK775, CGC_NK775
Notes: qyEx117 [C14A11.3a,c::GFP + unc-119(+)]. Maintain by picking non-Unc.|"Supplementary_genotype qyEx117 [pcgef-1a,c::GFP + unc-119(+)]"
Proper citation: RRID:WB-STRAIN:WBStrain00028872 Copy
http://www.wormbase.org/db/get?name=WBStrain00028866
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:38177158
Synonyms: unc-119(ed4) III; qyIs127.
Alternate IDs: WB-STRAIN:NK696, CGC_NK696
Notes: qyIs127 [lam-1p::lam-1::mCherry + unc-119(+)] V. Reference: Ihara S, et al. Nat Cell Biol. 2011 Jun;13(6):641-51.|"qyIs127 [lam-1p::lam-1::mCherry + unc-119(+)]. Likely integrated on IV or V. Reference: Ihara S, et al. Nat Cell Biol. 2011 Jun;13(6):641-51."
Proper citation: RRID:WB-STRAIN:WBStrain00028866 Copy
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