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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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IA441 Resource Report Resource Website |
RRID:TSC_SD01577 | Tetrahymena thermophila | hpo1-2 strongly antagonizes the broadening of CVP domains brought about by bcd1-1; the resulting phenotype is a compromise between the broadening of the CVP domains brought about by bcd1 and the narrowing of these domains generated by hpo1 Submitted by Joseph Frankel, University of Iowa | HPO1 (hypoangular1), BCD1 (broadened cortical domains1) | SD01577 | hpo1-2/hpo1-2; bcd1-1/bcd1-1 (hpo1-2; bcd1-1; hpo1, bcd1, IV) | TSC, Tetrahymena Stock Center | TSC | PMID:8253268 | 2026-08-29 04:08:40 | 0 | |||||
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cTTMGHA Resource Report Resource Website |
RRID:TSC_SD01216 | Tetrahymena thermophila | Progeny of GTUKO5 x GTUKO6 mating, rescued by biolistic transformation with pTTMG-HA ( GTU-HA fusion driven by MTT1 promoter at the MTT1 locus). Needs 0.1μg/ml to 0.5 μg/ml Cd to grow, depending on the growth medium. Can cross with cTTMG-HA#15 or #14 From the Gorovsky lab, University of Rochester. | GTU1 (TTHERM_00079520) | Micronucleus: GTU1 gene replaced by neo2 cassette Macronucleus: HA tagged GTU1 gene into the MTT1 coding region | SD01216 | gtu1::neo2/gtu1::neo2;Chx1/Chx1; Mpr?/Mpr? (MTT1/GTU1[HA]; gtu1::neo2/gtu1::neo2; pm-r, BTU1 has(E431,435D), BTU2 is replaced by bsr1, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:12356864 | 2026-08-29 04:08:40 | 0 | ||||
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IA137 Resource Report Resource Website |
RRID:TSC_SD01457 | Tetrahymena thermophila | Incomplete fission-zone formation with arrest in late-cytokinesis, with the new oral apparatus often abnormal and frequently wedged within the arrested furrow (39°). Fairly high lethality in crosses. Clear-cut temperature-sensitive expression: no expression at 28°, penetrance high but not 100% at 39° C. Submitted by Joseph Frankel, University of Iowa | CDAE (cell division arrest E). (Originally published as mo8). | SD01457 | cdaE-1/cdaE-1 (cdaE-1, V) | TSC, Tetrahymena Stock Center | TSC | PMID:821816 PMID:407114 |
2026-08-29 04:08:40 | 0 | |||||
|
pBBN-CDC2 5’ 727-GFP (2) Resource Report Resource Website |
RRID:TSC_SD02823 | Tetrahymena thermophila | Complete somatic transformant of CU522 cells. Construct was pBBN-CDC2: BTU1 5’(600bp from400-1000bp upstream of BTU1 ATG)--Neo3--CDC2 5’flanking 946 bp immediately upstream of ATG--GFP coding- -1.4 Kb BTU1 3â€Â. BTU1 promoter was deleted. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | CDC2 (TTHERM_01207660) | Macronucleus: BTU1 locus replaced by far 5’BTU1 5’--neo3--CDC2 5’ flanking 946 bp immediately upstream of ATG--GFP coding--BTU1 3’ | SD02823 | btu1-1[K350M]/ btu1-1[K350M] (BTU1 locus replaced by far 5’BTU1 5’--neo3--CDC2 5’ flanking 946bp immediately upstream of ATG--GFP coding--BTU1 3’; pm-r with Cd+2; tax-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:15870266 PMID:17194754 |
2026-08-29 04:08:41 | 0 | ||||
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HA-TWI11 B1-1-1 Resource Report Resource Website |
RRID:TSC_SD02797 | Tetrahymena thermophila | heterozygote HA-tagged TWI11 heterokaryon. HA coding sequences was inserted just after the start codon of TWI11. Neo3 cassette was inserted to upstream of TWI11 mates with HA-TWI11 B1-2-3. From the Gorovsky lab, University of Rochester. | TWI11 (TTHERM_00144830) | Micronucleus: HA tagged TWI11 | SD02797 | TWI11/twi11[5’neo3,HAn];MPR1/mpr1-1 (mpr1-1; mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:42 | 0 | |||||
|
B2086 II Resource Report Resource Website 10+ mentions |
RRID:TSC_SD01625 | Tetrahymena thermophila | All three B2086 clones were used extensively for crosses in the Frankel lab in the late 1980's and 1990's. Submitted by Joseph Frankel, University of Iowa | SD01625 | mat1-2/mat1-2 (mat1-2, II) | TSC, Tetrahymena Stock Center | TSC | PMID:8253268 | 2026-08-29 04:08:41 | 21 | ||||||
|
∆H3 gl 2.6 Resource Report Resource Website |
RRID:TSC_SD01869 | Tetrahymena thermophila | This is the germline KO homozygous heterokaryon. Both copies of major histone H3 were removed. Also HHF2 and intergenic region connecting it to HHT2. KO with Neo cassette. The ∆H3 gl 2.* series have a different mating type from the ∆H3 gl 10.* series From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170) | Micronucleus: Neo2 KO of HHT1 and HHT2/HHF2 | SD01869 | hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; mpr1-1/mpr1-1 (mpr1-1; pm-s, mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 | 2026-08-29 04:08:41 | 0 | ||||
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RPA5-HA-8 Resource Report Resource Website |
RRID:TSC_SD02718 | Tetrahymena thermophila | All Somatic copy of RPA5 was replaced with RPA5-HA construct, neo3, CU428background. RPA5 is the fifth largest subunit of pol I and III. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | RPC5 (TTHERM_00094210) | Macronucleus: HA tagged RPC5 | SD02718 | mpr1-1/mpr1-1 (rpc5[3’neo3,HAc]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:15470252 | 2026-08-29 04:08:42 | 0 | ||||
|
B2KO-5 Resource Report Resource Website |
RRID:TSC_SD01909 | Tetrahymena thermophila | Heterozygous germline transformant of BTU2 knockout. Derived from Cu428 X B2086 transformed w/ BHAB-2 (construct). When crossed to CU427, gave cyr and pmr progeny. Can mate to B2KO-6. Created 12/29/97, in soybean until 4/98. B2KO-6 mates with B2KO-1,2,3,4,5,7,8. No others mated. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | BTU2 (TTHERM_00836580) | Micronucleus: H4-neo replaces BTU2 coding Macronucleus: H4-neo replaces BTU2 coding | SD01909 | BTU2/btu2[∆,::H4-neo]; MPR1-1/mpr1-1 (BTU2/btu1[∆,::H4-neo]; MPR1-1/mpr1-1; mp-r, pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:10831613 | 2026-08-29 04:08:41 | 0 | ||||
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IA123 Resource Report Resource Website |
RRID:TSC_SD01511 | Tetrahymena thermophila | Failure to complete cytokinesis accompanied by cell elongation (>36o C). Located on chromosome 5. Allelic to cdaC-1 (IA-119). Expresses 100% fission blockage at temperatures of 36o C. and higher. Submitted by Joseph Frankel, University of Iowa | CDAC (cell division arrest C) Originally published as mo3b | SD01511 | cdaC-2/cdaC-2 (cdaC-2, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:407114 PMID:821816 |
2026-08-29 04:08:41 | 0 | |||||
|
IA107 Resource Report Resource Website |
RRID:TSC_SD01510 | Tetrahymena thermophila | Partial failure to form a fission zone (39o C.) Fully penetrant at 39o C, but expressivity is far weaker than that of cdaA-1 at 39o, and instead resembles that of cdaA-1 at 35o C: dorsal ciliary rows remain continuous while ventral rows become subdivided, and a partial division furrow forms. Allelic to cdaA-1 (IA-104). The published phenotypic analysis was carried out on a different homozygous cdaA-2/cdaA-2 clone that is now extinct. Submitted by Joseph Frankel, University of Iowa | CDAA (cell division arrest A) Originally published as mo1b | SD01510 | cdaA-2/cdaA-2 (cdaA-2, III) | TSC, Tetrahymena Stock Center | TSC | PMID:821816 PMID:407114 |
2026-08-29 04:08:41 | 0 | |||||
|
SB1969 Resource Report Resource Website 10+ mentions |
RRID:TSC_SD00701 | Tetrahymena thermophila | Cycloheximide resistance functional heterokaryon. | SD00701 | chx1-1/chx1-1 (CHX1; cy-s, II) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:41 | 10 | |||||||
|
VPS13A::GFP Resource Report Resource Website |
RRID:TSC_SD01757 | Tetrahymena thermophila | Deposited line has been grown with high concentration of paromomycin (1 mg/ml) for phenotypic assortment, but it has not been subcloned. Gene has also been referred to as TtVPS13A. Stock has been maintained in SSP medium + 2 ug/ml CdCl2 + 1 mg/ml paromomycin. Submitted by Lawrence Klobutcher, University of Connecticut Health Center | Vacuolar Protein Sorting 13A gene | SD01757 | mpr1-1/mpr1-1; VPS13A/VPS13A (MPR1; VPS13A/vps13a-2::gfp; pm-r, mp-s, VII, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:21764909 | 2026-08-29 04:08:41 | 0 | |||||
|
IA285 Resource Report Resource Website |
RRID:TSC_SD01517 | Tetrahymena thermophila | Pleiotropic: elongated phenotype with development of large oral-replacement or misplaced cell division oral primordia, especially in rich medium, at 39o C. Also frequent abnormal internal organization of oral structures, and fission arrest. The only known mutant allele of this gene, located on chromosome 3R. This is the most highly pleiotropic of the PSM mutant genes. Submitted by Joseph Frankel, University of Iowa | PSMD (pseudomacrostome D) | SD01517 | psmD1/psmD-1 (psmD-1, III) | TSC, Tetrahymena Stock Center | TSC | PMID:6491585 PMID:18658256 |
2026-08-29 04:08:42 | 0 | |||||
|
DRH26sKO(7)-17-2 Resource Report Resource Website |
RRID:TSC_SD02604 | Tetrahymena thermophila | Somatic KO of .DRH26, neo3, CU427 background From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | EMA1 (TTHERM_00088150) | Macronucleus: Neo3 of EMA1 | SD02604 | chx1-1/chx1-1 (ema1[∆?::neo3]; pm-r, VI) | TSC, Tetrahymena Stock Center | TSC | PMID:18708581 | 2026-08-29 04:08:41 | 0 | ||||
|
gl∆H3/H4 major, #7 Resource Report Resource Website |
RRID:TSC_SD01362 | Tetrahymena thermophila | Germline heteokaryon Major H3 and H4 genes knocked out with neo cassette.It mates with gl∆H3/H4 #4 strain. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170) | Micronucleus: Neo KO of all major HHT genes and HHF genes | SD01362 | hhf1[∆::neo1]/hhf1[∆::neo1]; hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; (mp-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:15701804 | 2026-08-29 04:08:42 | 0 | ||||
|
CDC5’ 0-GFP-CDC3’-neo3 (XS73) Resource Report Resource Website |
RRID:TSC_SD02573 | Tetrahymena thermophila | XS72 Somatic transformant obtained by shooting CU428 X B2086 exconjugant cells. In CDC2 locus, coding region replaced by GFP coding. Shortened CDC2 5’ flanking region is 0 bases but the CDC2 far 5’ flanking 1 kb sequence that is 1.6 b upstream of the ATG was used to do the homologous recombination. Neo3 cassette is in 3’ flanking region. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | CDC2 (TTHERM_01207660) | Macronucleus: CDC2 gene has the 1.6 kb just upstream of ATG lacking and GFP coding replacing CDC2 coding. Also neo3 in 3’ flanking. region. | SD02573 | ? (Partial replacement CDC2/cdc2-? CDC2 gene 5’ flanking sequence of 0 bp with GFP coding replacing CDC2 coding. Also neo3 in 3’ flanking.; pm-r with Cd+2, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:15870266 PMID:17194754 |
2026-08-29 04:08:41 | 0 | ||||
|
C3 491 6b Resource Report Resource Website |
RRID:TSC_SD00034 | Tetrahymena thermophila | See Figure 1 on page 13 of Methods in Cell Biology Volume 62, Tetrahymena thermophila 2000 (Editors D.J. Asai and J.D. Forney) for and excellent diagram explaining how the inbred strains are related to each other. Submitted by Eileen Hamilton, University of California, Santa Barbara | SD00034 | wild type C3 (wild type C3; wild type C3, VI) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:41 | 0 | |||||||
|
CU5002 Resource Report Resource Website |
RRID:TSC_SD01127 | Tetrahymena thermophila | SD01127 | chx1-1/chx1-1; Del 5 (CHX1; cy-s, VI) | TSC, Tetrahymena Stock Center | TSC | 2026-08-29 04:08:41 | 0 | ||||||||
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H3E-1 Resource Report Resource Website |
RRID:TSC_SD01886 | Tetrahymena thermophila | Single cell line from H3E transformant. By antiphos H3 antibody staining, no stain so should be all HHT2 S10A. Also checked by Southern. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT1 (TTHERM_00570560), HHT2 (TTHERM_00189180) | Macronucleus: KO of HHT1, HHT2 has mutation S10A | SD01886 | chx1-1/chx1-1 (?HHT1/hht1[∆::neo2; hht2[3’neo2, S10A]; Somatic ∆HHT1 with neo cassette and HHT2S10A (neo in 3 flank) cotransformant., VI) | TSC, Tetrahymena Stock Center | TSC | PMID:10199406 PMID:9636175 |
2026-08-29 04:08:41 | 0 |
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