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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BB/N Resource Report Resource Website |
RRID:RGD_61011 | Rattus norvegicus | Mutation causing diabetes mellitus in a closed colony of outbred Wistar rats at Bio-Breeding Labs, Ontario, Canada in 1974 (Chappel and Chappel 1983). To Worcester in 1977 where inbreeding began. Sublines of diabetic-prone and diabetic-resistant animals have been developed, and there are also subline differences in the incidence, age of onset, untreated survival time of diabetes, leucopenia and body weight gain which can be attributed to genetic factors (Kloting et al 1987). A detailed study of 24 inbred and two outbred lines of diabetes-prone and diabetes resistant BB rats using eight marker loci found substantial genetic variation among and some variation within some of the colonies. The 22 colonies which were apparently isogenic could be divided into four groups on the basis of the marker loci (Prins et al 1990). | 61011 | inbred | Rat Genome Database (RGD) | RGD | Extinct | 61011 | 2026-09-05 06:52:05 | 0 | |||||
|
LE/Mol Resource Report Resource Website |
RRID:RGD_10019 | Rattus norvegicus | 10019 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 10019 | 2026-09-05 06:52:04 | 0 | ||||||
|
IS/Kyo Resource Report Resource Website |
RRID:RGD_10018 | Rattus norvegicus | Ishibashi rat is derived from a cross between a wild male and a Wistar female, with sib mating since 1975 at Azabu University, transferred to Kyoto University in 1978. National BioResource Project for the Rat in Japan | 10018 | inbred | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo; Cryopreserved Sperm | 10018 | 2026-09-05 06:52:04 | 0 | |||||
|
BUF/Pit Resource Report Resource Website |
RRID:RGD_10010 | Rattus norvegicus | 10010 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 10010 | 2026-09-05 06:52:04 | 0 | ||||||
|
FHH/Eur Resource Report Resource Website |
RRID:RGD_10015 | Rattus norvegicus | An outbred stock of fawn hooded rats introduced into Europe by Tschopp in the early 1970s. Maintained as an outbred stock until the mid-1980s, then brother x sister mating initiated by A.P. Provoost to produce two strains designated FHH (also known as FHR) and FHL, which differ in hypertension and proteinuria. The colony was transferred to Erasmus University. | 10015 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 10015 | 2026-09-05 06:52:04 | 0 | |||||
|
F344/Pit Resource Report Resource Website |
RRID:RGD_10014 | Rattus norvegicus | 10014 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 10014 | 2026-09-05 06:52:04 | 0 | ||||||
|
SHR Resource Report Resource Website 1+ mentions |
RRID:RGD_61000 | Rattus norvegicus | Okamoto 1963 from outbred Wistar Kyoto rats. Bred from a male with mild hypertension, mated with a female with high blood pressure. Brother x sister mating with continued selection for high blood pressure (Okamoto 1969, Okamoto et al 1972). A number of sublines have been developed with a tendency to develop cardiovascular lesions and stroke (see particularly SHRSP) (Nagaoka et al 1976), and hypercholesterolemia (Yamori 1984). For a recent review see Yamori, (1994). However, there is no evidence for substrain differentiation among SHR stocks from the major commercial suppliers in the USA both respect to phenotype and DNA fingerprints (Blizard et al, 1991). Strain WKY, developed from the same base populations is sometimes used as a normotensive control, though its use as such must be questioned as it differs at many genetic marker loci (Festing and Bender 1984, and see also strain WKY). Stelzin et al (1992) found that SHR and WKY shared only 50% of their DNA fingerprint bands, whereas SS and SR shared about 80% of bands. Most authorities suggest that WKY alone is not a good control strain, and that for most comparative studies several normotensive strains should be used. There is an extensive literature on the characteristics of SHR. DeJong (1984) provides a useful comparative review of this and other hypertensive strains, and there are regular symposia on hypertensive rat strains (see J. Hypertension 4(suppl):S1-S541, 1986, and Jpn. Heart J. 28:567-648). | 61000 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 61000 | 2026-09-05 06:52:05 | 7 | |||||
|
MR/Pit Resource Report Resource Website |
RRID:RGD_10029 | Rattus norvegicus | As for MNR except selection was for high defecation response in the open field. To Harrington in 1965 at F25 and to NIH in 1964 at F18+ (Hansen et al 1982). | 10029 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 10029 | 2026-09-05 06:52:04 | 0 | |||||
|
LH/Mav Resource Report Resource Website |
RRID:RGD_10021 | Rattus norvegicus | In 1969 outbred Sprague-Dawley rats were selected for high systolic blood pressure using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LN was maintained as a normotensive control, and LL as a hypotensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews). | 10021 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 10021 | 2026-09-05 06:52:04 | 0 | |||||
|
MNR/N Resource Report Resource Website |
RRID:RGD_10026 | Rattus norvegicus | To N 1964 at F18+? from Maas. Developed by Broadhurst, 1954, from a commercial stock, with selection for low defecation response in an open field. A number of parallel sublines are in existence; these differ at least at the agouti and the major histocompatibility loci. | 10026 | inbred | Rat Genome Database (RGD) | RGD | Extinct | 10026 | 2026-09-05 06:52:04 | 0 | |||||
|
MNRA/N Resource Report Resource Website |
RRID:RGD_10027 | Rattus norvegicus | To Harrington in 1965 at F25 (Harrington 1981). | 10027 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 10027 | 2026-09-05 06:52:04 | 0 | |||||
|
AGUS Resource Report Resource Website |
RRID:RGD_70425 | Rattus norvegicus | Germ-free strain developed by Gustafsson from stock (Sprague-Dawley?) by hysterectomy derivation in 1948 at F10. To Laboratory Animals Centre, Carshalton 1968 at F26. | 70425 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 70425 | 2026-09-05 06:52:06 | 0 | |||||
|
NZR Resource Report Resource Website |
RRID:RGD_68107 | Rattus norvegicus | Subline of AS2 separated at F32. | 68107 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 68107 | 2026-09-05 06:52:05 | 0 | |||||
|
NBL Resource Report Resource Website |
RRID:RGD_68100 | Rattus norvegicus | Bogden in the mid-1970s from Noble (Nb) strain rats (brother x sister mated but not descended from a single pair, and therefore not necessarily isogenic). To Fredrich Cancer Research facility in 1978. Note that the strain name NBL was selected in 1989. In the literature these rats are called Noble or Nb rats, usually without identifying whether the animals came from the non-isogenic colony of Dr. Noble or from the isogenic colony at the National Cancer Institute (Greenhouse et al 1990). | 68100 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 68100 | 2026-09-05 06:52:05 | 0 | |||||
|
HTX/Hcj Resource Report Resource Website |
RRID:RGD_68189 | Rattus norvegicus | D. F. Kohn, Inst. of Comparative Medicine,Columbia University, to University of Florida 1992 at F30. | 68189 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 68189 | 2026-09-05 06:52:06 | 0 | |||||
|
NER Resource Report Resource Website |
RRID:RGD_68103 | Rattus norvegicus | From Crj: Wistar rats purchased from Charles River Japan in July 1985. Developed by A. Noda, Tokyo University of Agriculture, Hokkaido, from a cross of mutant rats with spontaneous tonic-clonic seizures (Noda et al. 1998). Susceptible to seizures induced by pentylenetetrazol, tossing and transcorneal electric shock, but not tactile, photic or acoustic stimuli or transauricular electric shock. No pathologic changes have been found in the CNS. The condition appears to be inherited as an autosomal recessive gene and is comparable to generalised tonic-clonic seizures in humans. Maintained by Has. | 68103 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 68103 | 2026-09-05 06:52:05 | 0 | |||||
|
WOKW Resource Report Resource Website |
RRID:RGD_67935 | Rattus norvegicus | Outbred Wistar BB rats from Biobreeding Laboratories, Ottawa, Canada in 1981 to Dr.I. Kloting, Dept. of Laboratory Animal Science, Inst. of Pathology, University of Greifswald,D-17495, Karlsburg, Germany. WOKA (originally designated WOK.1A) was developed by brother x sister mating from rats homozygous for RT1a, and WOKW (originally designated WOK.1W) from rats homozygous for RT1U , a haplotype which pre-disposes to type I diabetes. | 67935 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 67935 | 2026-09-05 06:52:05 | 0 | |||||
|
GH Resource Report Resource Website |
RRID:RGD_60984 | Rattus norvegicus | University of Otago Medical School from rats of Wistar origin imported from England in 1930. Selection for high blood pressure started by Smirk in 1955. A number of sublines have been developed. Closely related to strain AS (Heslop and Phelan 1973). | 60984 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 60984 | 2026-09-05 06:52:05 | 0 | |||||
|
WST Resource Report Resource Website |
RRID:RGD_67937 | Rattus norvegicus | Strain WAG, Glaxo Research, Uxbridge, UK to Institute of Rheumatology, Warsaw in 1964. To Institute of Oncology, Warsaw 1964. To Institute of Occupational Medicine (Imp), Warsaw in 1965 (Pietrowicz 1986). | 67937 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 67937 | 2026-09-05 06:52:05 | 0 | |||||
|
AMDIL Resource Report Resource Website |
RRID:RGD_70428 | Rattus norvegicus | Torres, Rio de Janeiro, from outbred stock | 70428 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 70428 | 2026-09-05 06:52:06 | 0 |
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