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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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SD;DA-Tg(Thy1-APP*)1Dspb Resource Report Resource Website |
RRID:RGD_38599241 | Rattus norvegicus | Mutant human amyloid beta (APP*) combined Thy1 promoter which is specifically expressed in neurons, was induced to ES cells from DA strain rats, and chimera rats obtained from the ES cells. The F1 rats were backcrossed with Crl:CD (SD) strain rats and F3 rats was deposited to NBRP. The expression levels of mutant human APP mRNA are different among Lines (12>1>14>6). National BioResource Project for the Rat in Japan | 38599241 | transgenic | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-09-16) | 38599241 | 2026-08-29 11:49:57 | 0 | |||||
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LE-Tg(Tac1-cre)4-1Koba Resource Report Resource Website |
RRID:RGD_38599247 | Rattus norvegicus | Background strain: Long-Evans rat (Iar:Long-Evans, RGD:18337282). This strain was established by injection of modified BAC (cre gene was inserted into the exon 2 of rat Tac1 gene) into Long-Evans rat's fertile eggs.This transgenic strain expresses Cre recombinase under the control of Tac1 promoter. The expression levels of Cre recombinase in LE-Tg(Tac1-cre)4-1Koba are higher than in LE-Tg(Tac1-cre)6-7Koba (RGD:38599245). National BioResource Project for the Rat in Japan | 38599247 | transgenic | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-09-16) | 38599247 | 2026-08-29 11:49:57 | 0 | |||||
|
LE-Tg(Tac1-cre)6-7Koba Resource Report Resource Website |
RRID:RGD_38599245 | Rattus norvegicus | Background strain: Long-Evans rat (Iar:Long-Evans, RGD:18337282). This strain was established by injection of modified BAC (cre gene was inserted into the exon 2 of rat Tac1 gene) into Long-Evans rat's fertile eggs. This transgenic strain expresses Cre recombinase under the control of Tac1 promoter. The expression levels of Cre recombinase in LE-Tg(Tac1-cre)6-7Koba are lower than in LE-Tg(Tac1-cre)4-1Koba (RGD:38599247) National BioResource Project for the Rat in Japan | 38599245 | transgenic | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-09-16) | 38599245 | 2026-08-29 11:49:57 | 0 | |||||
|
SD;DA-Tg(Thy1-APP*)12Dspb Resource Report Resource Website |
RRID:RGD_38599243 | Rattus norvegicus | Mutant human amyloid beta (APP*) combined Thy1 promoter which is specifically expressed in neurons, was induced to ES cells from DA strain rats, and chimera rats obtained from the ES cells. The F1 rats were backcrossed with Crl:CD (SD) strain rats and F3 rats was deposited to NBRP. The expression levels of mutant human APP mRNA are difficult among Lines (12>1>14>6). National BioResource Project for the Rat in Japan | 38599243 | transgenic | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-09-16) | 38599243 | 2026-08-29 11:49:57 | 0 | |||||
|
MWF.SHR-(D6Rat1-D6Rat81)/Rkb Resource Report Resource Website |
RRID:RGD_150429606 | Rattus norvegicus | The congenic MWF.SHR-(D6Rat1-D6Rat81)/Rkb was generated by transfer of different nested SHR/FubRkb segments onto the MWF/FubRkb background. For this procedure, male and female rats of the MWF-6SHR (RGD:1641831) breeding, that were homozygous for all MWF chromosomes except RNO6 and heterozygous for RNO6, were intercrossed. Eight congenics were generated. | 150429606 | congenic | Rat Genome Database (RGD) | RGD | Unknown | 150429606 | 2026-08-29 11:49:57 | 0 | |||||
|
MWF.SHR-(D6Rat1-D6Mgh4)/Rkb Resource Report Resource Website |
RRID:RGD_150429605 | Rattus norvegicus | The congenic MWF.SHR-(D6Rat1-D6Mgh4)/Rkb was generated by transfer of different nested SHR/FubRkb segments onto the MWF/FubRkb background. For this procedure, male and female rats of the MWF-6SHR (RGD:1641831) breeding, that were homozygous for all MWF chromosomes except RNO6 and heterozygous for RNO6, were intercrossed. Eight congenics were generated. | 150429605 | congenic | Rat Genome Database (RGD) | RGD | Unknown | 150429605 | 2026-08-29 11:49:57 | 0 | |||||
|
MWF.SHR-(D6Rat1-D6Rat121)/Rkb Resource Report Resource Website |
RRID:RGD_150429604 | Rattus norvegicus | The congenic MWF.SHR-(D6Rat1-D6Rat121)/Rkb was generated by transfer of different nested SHR/FubRkb segments onto the MWF/FubRkb background. For this procedure, male and female rats of the MWF-6SHR (RGD:1641831) breeding, that were homozygous for all MWF chromosomes except RNO6 and heterozygous for RNO6, were intercrossed. Eight congenics were generated. | 150429604 | congenic | Rat Genome Database (RGD) | RGD | Unknown | 150429604 | 2026-08-29 11:49:57 | 0 | |||||
|
SD-Disc1em1Rst Resource Report Resource Website |
RRID:RGD_125093746 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 371-bp deletion of exon 2 in the rat Disc1 gene of one-cell Crl:SD embryos. This deletion caused non-sense mutation and early termination of translation. | 125093746 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 125093746 | 2026-08-29 11:49:57 | 0 | |||||
|
SD-Trpm4em1Sage Resource Report Resource Website |
RRID:RGD_150521556 | Rattus norvegicus | Trpm4 gene specific Zinc finger constructs directed against exons 18-19, which contain the coding sequence for TM3-5 and the pore region of the TRPM4 protein, were injected in zygotes from Sprague-Dawley rats. This mutant rat with a 514 bp deletion which includes completely removes exon 18 and a piece of exon 19 from the Trpm4 gene, plus the intron 18-19. The deletion was confirmed via genomic sequencing and western blotting. | 150521556 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 150521556 | 2026-08-29 11:49:57 | 0 | |||||
|
BN/HsdShulRrrc Resource Report Resource Website |
RRID:RGD_150521677 | Rattus norvegicus | Inbred substrain derived from BN/SsNHsd(RGD:10008) | 150521677 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 150521677 | 2026-08-29 11:49:58 | 0 | |||||
|
F344-Ppargm1Kyo Resource Report Resource Website |
RRID:RGD_38676254 | Rattus norvegicus | By using ENU mutagenesis followed by MuT-POWER screening of the KURMA (Kyoto University Rat Mutant Archive) samples, the depositors generated a heterozygous PPARg mutant (Ppargmkyo/+) rat with a missense mutation (G488T p.C163F in Pparg1 or G578T p.C193F for Pparg2) in Pparg. The PpargG488T homozygous rats are embryonic lethal. Heterozygous Ppargmkyo/+ rats showed reduced fat mass with adipocyte hypertrophy and insulin resistance, which were highly predictable from known actions of Pparg agonists and phenotypes of patients with the PPARG mutation. National BioResource Project for the Rat in Japan | 38676254 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-09-16) | 38676254 | 2026-08-29 11:49:57 | 0 | |||||
|
F344-Hcn1em1Kyo Resource Report Resource Website |
RRID:RGD_38676253 | Rattus norvegicus | TALEN (Left: ttcagAATGATTCATGGG, Right : ACGCACTCTTCAAAGCTA) targeting the exon4 of hyperpolarization-activated cyclic nucleotide-gated 1 channel (Hcn1) gene was designed and mRNA coding these TALEN was microinjected into F344/NSlc embyo. A 7-bp deletion in the exon4 of Hcn1 gene: as a result of frameshift mutation, stop codon is produced. Decreased expression levels of Hcn1 gene and HCN1 protein. National BioResource Project for the Rat in Japan | 38676253 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-09-16) | 38676253 | 2026-08-29 11:49:57 | 0 | |||||
|
F344-Hcn1em2Kyo Resource Report Resource Website |
RRID:RGD_38676251 | Rattus norvegicus | TALEN (Left: ttcagAATGATTCATGGG, Right : ACGCACTCTTCAAAGCTA) targeting the exon4 of hyperpolarization-activated cyclic nucleotide-gated 1 channel (Hcn1) gene was designed and mRNA coding these TALEN was microinjected into F344/NSlc embyo. A 24-bp deletion in the exon4 of Hcn1 gene. It is predicted that 8 amino-acid deleted HCN1 protein is expressed. National BioResource Project for the Rat in Japan | 38676251 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-09-16) | 38676251 | 2026-08-29 11:49:57 | 0 | |||||
|
CD-Tg(RNECO-180E22)424Arno Resource Report Resource Website 1+ mentions |
RRID:RGD_155663366 | Rattus norvegicus | This transgenic model line 424 was made by injecting bacterial artificial chromosome (BAC) RNECO-180E22, into Crl:CD(SD) strain embryos. The BAC clone RNECO-180E22, a kind gift of Helen Skaletsky, is derived from Rattus norvegicus strain SHR chromosome Y. | 155663366 | transgenic | Rat Genome Database (RGD) | RGD | Unknown | 155663366 | 2026-08-29 11:49:59 | 1 | |||||
|
SD-Del(Yp)1Mcwi Resource Report Resource Website |
RRID:RGD_155663364 | Rattus norvegicus | CRISPR guide RNAs flanking Sry4a and Sry1 (Sry) on the Y-chromosome were injected into Crl:SD strain embryos. Chromosomal deletions have not been explicitly defined. | 155663364 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2022-11-11) | 155663364 | 2026-08-29 11:49:59 | 0 | |||||
|
CD-Tg(RNECO-180E22)208Arno Resource Report Resource Website 1+ mentions |
RRID:RGD_155663365 | Rattus norvegicus | This transgenic model line 208 was made by injecting bacterial artificial chromosome (BAC) RNECO-180E22, into Crl:CD(SD) strain embryos. The BAC clone RNECO-180E22, a kind gift of Helen Skaletsky, is derived from Rattus norvegicus strain SHR chromosome Y. | 155663365 | transgenic | Rat Genome Database (RGD) | RGD | Unknown | 155663365 | 2026-08-29 11:49:59 | 1 | |||||
|
LEXF7B/StmMcwi Resource Report Resource Website |
RRID:RGD_156430085 | Rattus norvegicus | This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP | 156430085 | recombinant_inbred | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo (as of 2023-10-24) | 156430085 | 2026-08-29 11:49:58 | 0 | |||||
|
Mlac:SD Resource Report Resource Website |
RRID:RGD_156420153 | Rattus norvegicus | This outbred Sprague Dawley was maintained at National Laboratory Animal Center (NLAC), Thailand. All animals were housed at the Chulalongkorn University Laboratory Animal Center (CULAC) . National Laboratory Animal Center, Mahidol University Thailand | 156420153 | outbred | Rat Genome Database (RGD) | RGD | Unknown | 156420153 | 2026-08-29 11:49:58 | 0 | |||||
|
SD-Spon2em1Holi Resource Report Resource Website |
RRID:RGD_329333019 | Rattus norvegicus | This Spon2 knockout mutant was produced by injecting TALENs targeting exon 2 of rat Spon2 into Sprague Dawley embryos. Founder #4-1 (a1) carrying a 22-bp deletion was chosen to produce heterozygous and homozygous rats. | 329333019 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 329333019 | 2026-08-29 11:49:59 | 0 | |||||
|
LEXF3/StmMcwi Resource Report Resource Website |
RRID:RGD_156430080 | Rattus norvegicus | This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP | 156430080 | recombinant_inbred | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo (as of 2023-10-24) | 156430080 | 2026-08-29 11:49:58 | 0 |
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