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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430086
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-24)
Alternate IDs: 156430086
Notes: This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP
Proper citation: RRID:RGD_156430086 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155598601
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 155598601
Notes: CRISPR/Cas9 system was used to introduce a 58-base pair deletion in exon 6 in the rat Bmal1 gene of Crl:SD embryos. The deletion caused a premature stop codon in exon 6 resulting in a severe truncation of the Bmal1 protein. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_155598601 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155782885
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 155782885
Notes: SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability.
Proper citation: RRID:RGD_155782885 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155782881
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 155782881
Notes: SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability.
Proper citation: RRID:RGD_155782881 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155782880
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 155782880
Notes: SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability.
Proper citation: RRID:RGD_155782880 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155631289
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 155631289
Notes: This mutant strain was generated by microinjecting CRISPRs/Cas9 system targeting rat Pde6b. Pde6b knock out rat was successfully created. Cyagen Biosciences Inc, Santa Clara, CA, USA
Proper citation: RRID:RGD_155631289 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155630633
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 155630633
Notes: The mutant rat was produced by injecting Crl:CD(SD) zygotes with gRNA +Cas9 ribonucleoprotein complex targeting exon 3 of rat Ctns. The founder of this strain possessed a 8-bp insertion which results in frameshift and pre-mature stop truncated protein.
Proper citation: RRID:RGD_155630633 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155631285
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 155631285
Notes: PAC671D9 (AF031078) DNA containing all the exons of human MECP2 was injected to SD embryos to generate MECP2 duplication rat.
Proper citation: RRID:RGD_155631285 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155782914
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 155782914
Notes: SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability.
Proper citation: RRID:RGD_155782914 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155631278
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 155631278
Notes: This mutant strain was generated by electroporating rat zygotes with CRISPRs/Cas9 system targeting exon12 of rat Flna into Crl:SD embryo. This mutant strain carries P637Q knock in the gene.
Proper citation: RRID:RGD_155631278 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155782879
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 155782879
Notes: SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability.
Proper citation: RRID:RGD_155782879 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155782877
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals (as of 2022-12-07)
Alternate IDs: 155782877
Notes: Imported from Kyoto University in 2010, now maintained at Molecular Embryological & DNA Methylation Lab at National Chung Hsing University, Taiwan.
Proper citation: RRID:RGD_155782877 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156420139
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2024-08-06)
Alternate IDs: 156420139
Notes: These are re-derived rats of MNS/N now maintained at Medical College of Wisconsin. Origin: Wistar rats with brother x sister mating and selection for low systolic blood pressure as a normotensive control for MHS. RGD HRDP, contact Hybrid Rat Diversity Program at
[email protected]
Proper citation: RRID:RGD_156420139 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=288084580
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 288084580
Notes: This mutation Phe54Leu is an autosomal dominant mutation that appeared in a stock of F344/NSlc rats that had been mutagenized with N-ethyl-N-nitrosourea (ENU). Rats heterozygous for Txn1 (Txn1 /+) exhibited running seizures only in its juvenile stage. The rat called Adem rat, exhibited age dependent mitochondrial cytopathy (Adem). The rats were backcrossed for more than ten generations on the F344/NSlc inbred background to ensure other mutations induced by ENU was reduced. The causative gene was identified as a missense substitution (c. 160 T > C, p. Phe54Leu) in exon 3 of Txn1.
Proper citation: RRID:RGD_288084580 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155641235
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 155641235
Notes: 3 pairs of WKY males and females with highest immobility and lowest climbing scores in the forced swim test were mated. Dept. of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Rat Resource and Research Center
Proper citation: RRID:RGD_155641235 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155641237
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 155641237
Notes: 3 pairs of WKY males and females with lowest immobility and highest climbing scores in the forced swim test were mated. Dept. of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Now deposited at
Rat Resource and Research Center
Proper citation: RRID:RGD_155641237 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155641245
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 155641245
Notes: Targeted knock-in adding a T2A-iCre to the Oprm1 (mu opioid receptor) in this cre recombinase reporter SD rat This rat was produced by Optogenetics and Transgenic Technology Core and now cryopreserved at RRRC.
Proper citation: RRID:RGD_155641245 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156451370
Source Database: Rat Genome Database (RGD)
Genetic Background: outbred
Availability: Unknown
Alternate IDs: 156451370
Notes: These low-alcohol-drinking were developed by selective breeding from the heterogeneous strain N:NIH (RGD:728185). 8 inbred rat strains were intercrossed for alcohol preference and consumption. Within-family selection and a rotational breeding design were employed to reduce inbreeding and to allow maintenance of non-inbred replicate lines.
Proper citation: RRID:RGD_156451370 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430169
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2023-02-22)
Alternate IDs: 156430169
Notes: The MeCP2 KO rat model was originally created at SAGE Labs,
Inc. in St. Louis, MO and distributed out of the Boyertown, PA
facility. The line continues to be maintained through the original
SAGE Labs animal inventory acquired by Envigo. The ZFN mutant rat strain was produced by injecting zinc finger nuclease targeting rat Mecp2 into Sprague Dawley embryos. This mutant rat has a knockout of the methyl CpG binding protein 2 (Mecp2). ENVIGO
Proper citation: RRID:RGD_156430169 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156451369
Source Database: Rat Genome Database (RGD)
Genetic Background: outbred
Availability: Unknown
Alternate IDs: 156451369
Notes: These high-alcohol-drinking rats were developed by selective breeding from the heterogeneous N/N (N:NIH) strain . 8 inbred rat strains were intercrossed for alcohol preference and consumption.Within-family selection and a rotational breeding design were employed to reduce inbreeding and to allow maintenance of non-inbred replicate lines
Proper citation: RRID:RGD_156451369 Copy
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