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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092605
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-28)
Alternate IDs: 598092605
Notes: This strain was established by a use of the BAC transgenic method with a technical support from the C.B.S.N resource (Dr. Kazuto Kobayashi, Fukushima Medical University, Dr. Yuchio Yanagawa, Gunma University Graduate School of Medicine). This transgenic rat was transported to The Jikei University School of Medicine, and cre recombinase expression was confirmed by crossing it with a reporter rat (NBRP Rat No: 0734). These rats are maintained in The Jikei University School of Medicine. Background strain: Crlj:WI.
Transgene: Dbh (dopamine beta-hydroxylase: rat), TetR (E.coli), VP16 protein minimal“F”-type activation domain (Herpes simplex virus), 2A (Thosea asigna virus), cre recombinase (P1 Phage), bGlobin polyA (rabbit), loxP (P1 phage). Detailed method (BAC transgenic method): a rat BAC clone was used (CH230-211J22). Combined mRNA for tTA and cre recombinase sequences is transcribed under the control of Dbh promoter. In translation step, the transcript is cut at the 2A peptide sequence, resulting in a separate protein production of tTA and Cre. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092605 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=597538592
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 597538592
Notes: For the generation of transgenic rats, the authors used a 190-kb fused AF163864 PAC/AC097478 BAC clone (Yamakado et al., 2012, PMID:22475625). It contained the entire human SNCA sequence (GenBank AF163864), with 30-kb upstream regulatory promoter sequences and a 45-kb flanking downstream region, cloned into pBACe3.6 vector as described previously. Transgenic rats were obtained by injecting the purified BAC fragment into fertilized Sprague–Dawley oocytes at a concentration of 1.5 µg/ml. A founder line displaying the highest integration number of BAC DNA construct was crossedbred to homozygosity.
Proper citation: RRID:RGD_597538592 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405849386
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 405849386
Notes: This is the wild type littermate of the hDNMT3A transgenic rats which were established using zygote microinjection of a bacterial artificial chromosome (BAC). The RP11-159D24 BAC (NCBI-ID:223335, Homo sapiens, GRCh38.p2: Chr. 2: 25,202,642-25,410,145, total length: 207,504 bp) containing DNMT3A (GRCh38.p2: 25,232,961,25,342,590, total length: 109,630 bp) was injected into rat zygotes (Rattus norvegicus, Sprague-Dawley, SD). The offspring were identified with 8 PCR primer-pairs that were specific for the RP11-159D24 sequence to detect positive transgenic ones and wild type littermates that did not carry the human transgene.
Proper citation: RRID:RGD_405849386 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=617256277
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-07-23)
Alternate IDs: 617256277
Notes: Cryopreserved sperm was obtained and recovered for SD-Tg(Camk2a-cre/ERT2)ZiRrrc (RRRC_00688; RGD ID: 13446407), and then back-crossed to the outbred Long-evans (LE) strain for 8 generations. This transgenic strain is a tamoxifen inducible Cre recombinase animal in the Long-evans strain, with targeted cre/ERT2 fusion protein expression in neural populations, and is suitable for crossing with loxP models also in the LE strain. Rat Resource and Research Center
Proper citation: RRID:RGD_617256277 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=632522749
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 632522749
Notes: This transgenic rat strain carrying human NR3C2 was developed on a Sprague-Dawley albino background. The transgene was constructed with the human NR3C2 (also know as MR) under the proximal P1 promotor in the 5′-flanking regions of exons 1alpha.
Proper citation: RRID:RGD_632522749 Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43563
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Uty
Source References: PMID: 21093264, PMID: 21530259
Alternate IDs: MMRRC_43563-UCD, MMRRC_043563, MMRRC_43563
Notes: Research areas: ; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043563-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43562
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Kdm5d
Source References: PMID: 6542174, PMID: 21530259, PMID: 9736773
Alternate IDs: MMRRC_43562-UCD, MMRRC_043562, MMRRC_43562
Notes: Research areas: ; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043562-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43602
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: |MCPyV_gp4|Gt(ROSA)26Sor
Alternate IDs: MMRRC_43602-MU, MMRRC_043602, MMRRC_4362
Notes: Research areas: Cancer, Dermatology, Models for Human Disease, Research Tools, Virology; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043602-MU Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43815
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: |cre|Zic4
Source References: PMID: 20885380
Alternate IDs: MMRRC_43815-UCD, MMRRC_043815, MMRRC_43815
Notes: Research areas: Neurobiology; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043815-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43798
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: creFcer1g
Alternate IDs: MMRRC_43798-UCD, MMRRC_043798, MMRRC_43798
Notes: Research areas: Neurobiology; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043798-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43816
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: cre/ERT2Cbln2
Alternate IDs: MMRRC_43816-UCD, MMRRC_043816, MMRRC_43816
Notes: Research areas: Neurobiology; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043816-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43834
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Alternate IDs: MMRRC_43834-JAX, MMRRC_043834, MMRRC_43834
Notes: Research areas: Immunology and Inflammation, Models for Human Disease; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043834-JAX Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43830
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Thy1|HA|KCNB1|
Source References: PMID: 22442077, PMID: 27798188, PMID: 28383553
Alternate IDs: MMRRC_43830-MU, MMRRC_043830, MMRRC_4383
Notes: Research areas: Apoptosis, Neurobiology; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043830-MU Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43855
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Dmp1|SOST|
Source References: PMID: 21140374, PMID: 28607813, PMID: 27704638, PMID: 25808845, PMID: 22075208
Alternate IDs: MMRRC_43855-UNC, MMRRC_043855, MMRRC_43855
Notes: Research areas: Apoptosis, Cancer, Cell Biology, Developmental Biology, Diabetes, Hematology, Immunology and Inflammation, Metabolism, Obesity, Reproduction, Research Tools; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043855-UNC Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43951
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: ATP2B4||lacZ|||Myh6||tTA
Source References: PMID: 29487197, PMID: 12933703, PMID: 8831492
Alternate IDs: MMRRC_43951-JAX, MMRRC_043951, MMRRC_43951
Notes: Research areas: Cardiovascular, Models for Human Disease, Research Tools; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043951-JAX Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43939
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Dmp1|PTH1R|
Source References: PMID: 18698360
Alternate IDs: MMRRC_43939-JAX, MMRRC_043939, MMRRC_43939
Notes: Research areas: Cell Biology, Developmental Biology, Metabolism, Models for Human Disease, Research Tools; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043939-JAX Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43958
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Cfh|Rpl10a|EGFP|
Source References: PMID: 24810037
Alternate IDs: MMRRC_43958-MU, MMRRC_043958, MMRRC_43958
Notes: Research areas: Neurobiology; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043958-MU Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1358305
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1358305
Notes: This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource
Proper citation: RRID:RGD_1358305 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1358306
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1358306
Notes: This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource
Proper citation: RRID:RGD_1358306 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1358304
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1358304
Notes: This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource
Proper citation: RRID:RGD_1358304 Copy
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