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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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  • Background:transgenic (facet)

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2,445 Results - per page

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Record Last Update Mentions Count
SD-Tg(Thy1-APPDI)BWevn
 
Resource Report
Resource Website
RRID:RRRC_00974 Rattus norvegicus This novel transgenic rat produces low levels of human familial cerebral amyloid angiopath (CAA) Dutch/Iowa E22Q/D23N mutant amyloid beta protein in brain and recapitulates many of the pathologic aspects of human small-vessel CAA. A pcDNA3 vector containing 2.1 kb of human APP (isoform 770) cDNA was used to introduce the mutations Swedish K670N/M671L, Dutch E693Q, and Iowa D694N using the QuikChange kit. The APP770-SwDI cDNA was amplified by PCR using primers containing the NheI five linker and SacII three linker. The PCR product of the APP770-SwDI was subcloned between exons II and IV of a Thy1.2 expression cassette using NheI and SacII restriction sites. The completed construct was microinjected into pronuclei of Sprague-Dawley single-cell embryos. Founder rats were identified by Southern blot analysis of tail DNA. Transgenic offspring were determined by PCR analysis of tail DNA. All subsequent analyses were performed with hemizygous transgenic rats. Rat Resource and Research Center 00974 transgenic Rat Resource and Research Center (RRRC) RRRC Cryorecovery (as of 2025-10-30) RGD_626168255, 626168255, RRRC_974, RRRC_0974, RRRC_00974 2026-09-05 02:46:56 0
SD-Tg(Fos-LacZ)Bhope
 
Resource Report
Resource Website
1+ mentions
RRID:RRRC_00865 Rattus norvegicus The lacZ gene was inserted between NcoI and SalI sites in exon 4 of the murine Fos gene . The linearized DNA was then microinjected into fertilized rat oocytes and line 1-8 was chosen for continuation. Rats were rederived from frozen embryos in 2002 and bred onto SD background for >35 generations at NIDA IRP (Bruce Hope lab) Rat Resource and Research Center 00865 transgenic Rat Resource and Research Center (RRRC) RRRC Unknown RGD_14390082, 14390082, RRRC_865, RRRC_0865, RRRC_00865 2026-09-05 02:46:55 2
LE-Tg(DIO-iRFP)3Ottc
 
Resource Report
Resource Website
1+ mentions
RRID:RRRC_00747 Rattus norvegicus The transgene contains Cre recombinase reporter rat expressing the red fluorescent protein gene (iRFP) driven by the EF1 alpha promoter. Optogenetics and Transgenic Technology Core, Rat Resource and Research Center 00747 transgenic Rat Resource and Research Center (RRRC) RRRC Cryopreserved Sperm; Cryorecovery RGD_9588559, 9588559, RRRC_747, RRRC_0747, RRRC_00747 2026-09-05 02:46:54 1
SD-Tg(ACE2)058Bryd
 
Resource Report
Resource Website
1+ mentions
RRID:RRRC_01012 Rattus norvegicus Genetic Alteration(s):human ACE2 gene under expression of the human ACE2 promoter. Eight copies of the transgene are randomly integrated into an as yet unknown insertion site. Deposited at Rat Resource and Research Center 01012 transgenic Rat Resource and Research Center (RRRC) RRRC Cryopreserved Embryo (as of 2025-11-06) RGD_629006611, 629006611, RRRC_1012, RRRC_01012 2026-09-05 02:46:56 1
W-Tg(CMV-Ddx54)37Tsuy
 
Resource Report
Resource Website
RRID:RGD_10045606 Rattus norvegicus This transgenic rat was established by microinjection of transgene consisting of Ddx54 gene (NM_001191548.1) driven by CMV promoter (pCMV-Tag2B) derived from cytomegalovirus into Wistar rat (SLC) pronuclear fertile eggs at UNITECH Co., Ltd. in 2007. National BioResource Project for the Rat in Japan 10045606 transgenic Rat Genome Database (RGD) RGD Unknown 10045606 2026-09-05 06:52:05 0
LE-Tg((ROSA)26Sor-CAG-tdTomato)24Jfhy
 
Resource Report
Resource Website
RRID:RGD_10045580 Rattus norvegicus Background strain: Long Evans | Transgene: CAG-loxP-flanked Neo/STOP cassette-tdTomato was inserted into mouse ROSA26 BAC (RP23 244D9). National BioResource Project for the Rat in Japan 10045580 transgenic Rat Genome Database (RGD) RGD Cryopreserved Embryo; Cryopreserved Sperm (as of 2016-11-15) 10045580 2026-09-05 06:52:05 0
W-Tg(CMV-Ddx54)19Tsuy
 
Resource Report
Resource Website
RRID:RGD_10045602 Rattus norvegicus This transgenic rat was established by microinjection of transgene consisting of Ddx54 gene (NM_001191548.1) driven by CMV promoter (pCMV-Tag2B) derived from cytomegalovirus into Wistar rat (SLC) pronuclear fertile eggs at UNITECH Co., Ltd. in 2007. National BioResource Project for the Rat in Japan 10045602 transgenic Rat Genome Database (RGD) RGD Unknown 10045602 2026-09-05 06:52:06 0
SS-F8em2Mcwi-Tg(ITGA2B-F8*)Mcwi
 
Resource Report
Resource Website
RRID:RGD_152975965 Rattus norvegicus This transgenic was produced by crossing the SS transgenic rat carrying Lentivirus constructs containing the 2bF8 vector [B-domain deleted human FVIII under control of ITGA2B (IIb) promoter] with an F8 knockout rat SS-F8em2Mcwi (RGD:152975964). This transgenic rat strain expressed B-domain deleted human F8 under the control of ITGA2B promoter in the absence of rat F8 product. contact MCW Rat Distribution at [email protected] 152975965 transgenic Rat Genome Database (RGD) RGD Unknown 152975965 2026-09-05 06:52:07 0
SD-Tg(Ren2)27
 
Resource Report
Resource Website
RRID:RGD_629501 Rattus norvegicus This is a hypertensive rat strain in which the mouse Ren2 renin gene along with its 5' and 3' flanking sequences were microinjected into fertilized eggs from a Hannover Sprague-Dawley (SD) background. 629501 transgenic Rat Genome Database (RGD) RGD Unknown 629501 2026-09-05 06:52:08 0
WIC-Tg(Oprk1-YFP*)1Utthe
 
Resource Report
Resource Website
RRID:RGD_152977768 Rattus norvegicus The KOR-Venus construct consisting of promoter of rat Oprk1 (opioid receptor, kappa 1) fused with Venus fluorescent protein, was introduced into fertilized eggs of Wistar rats (Crlj:WI, Charles River Japan). They were then crossed with Wistar-Imamichi rats (Iar:Wistar-Imamichi, Institute for Animal Reproduction) to maintain the strain. Transgenic rats expressing the fluorescent protein Venus under the control of the Oprk1 promoter. This strain is heterozygous. National BioResource Project for the Rat in Japan 152977768 transgenic Rat Genome Database (RGD) RGD Unknown 152977768 2026-09-05 06:52:10 0
SD-Tg(Rho*S334X)7Lav
 
Resource Report
Resource Website
RRID:RGD_1358305 Rattus norvegicus This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource 1358305 transgenic Rat Genome Database (RGD) RGD Unknown 1358305 2026-09-05 06:52:12 0
SD-Tg(Rho*S334X)9Lav
 
Resource Report
Resource Website
RRID:RGD_1358306 Rattus norvegicus This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource 1358306 transgenic Rat Genome Database (RGD) RGD Unknown 1358306 2026-09-05 06:52:12 0
SD-Tg(Rho*S334X)5Lav
 
Resource Report
Resource Website
RRID:RGD_1358304 Rattus norvegicus This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource 1358304 transgenic Rat Genome Database (RGD) RGD Unknown 1358304 2026-09-05 06:52:12 0
SD-Tg(Npy)400Mcwi
 
Resource Report
Resource Website
RRID:RGD_1357417 Rattus norvegicus 14.5 kb lambda clone of the rat Npy gene was subcloned with a polylinker that had NotI and EcoRI restriction sites. This transgene that was released by NotI digestion contained ~5kb 5'and ~1kb 3' and was injected into the pronuclei of fertilized SD rats. Founders were mated with SD females. F1 animals were mated with SD females till line 400 hemizygous animals were developed that had 5 copies of the Npy gene. 1357417 transgenic Rat Genome Database (RGD) RGD Unknown 1357417 2026-09-05 06:52:13 0
Eker-Tg(Tsc2)28Hin
 
Resource Report
Resource Website
RRID:RGD_1357182 Rattus norvegicus Wild type Tsc2 transgene was constructed from the Tsc2 cDNA from BN rat and was microinjected into single male pronuclei. Eggs were cultured and tranferred into female wistar which were mated with Eker rats. 1357182 transgenic Rat Genome Database (RGD) RGD Unknown 1357182 2026-09-05 06:52:13 0
LEC-Tg(ATP7B)Tohm
 
Resource Report
Resource Website
RRID:RGD_1559030 Rattus norvegicus A 4.5 kb fragment of human ATP7B cDNA was blunt-end ligated into the pCXN2 vector that contained the CAG promoter to generate pCXN2ATP7B which was microinjected into the pronuclei of LEC/Crlj. The transgenic founders were identified by the PCR analysis of the tail-DNA. National BioResource Project for the Rat in Japan 1559030 transgenic Rat Genome Database (RGD) RGD Cryopreserved Embryo; Cryopreserved Sperm 1559030 2026-09-05 06:52:16 0
DA-Tg(CAG-lacZ)30Jmsk
 
Resource Report
Resource Website
RRID:RGD_1554305 Rattus norvegicus lacZ cDNA was inserted in the EcoRI site of the pCAGGS expression vector. This DNA was microinjected into the DA/Crlj. The expression of the transgene was determined by beta-gal staining. National BioResource Project for the Rat in Japan 1554305 transgenic Rat Genome Database (RGD) RGD Cryopreserved Embryo 1554305 2026-09-05 06:52:17 0
SS-Tg(CAG-EGFP)43Mcwi
 
Resource Report
Resource Website
RRID:RGD_1642994 Rattus norvegicus This transgenic strain contains the enhanced green fluorescent protein gene drived by ubiquitous CAG promoter. This vector contains long terminal repeats with self-inactivating mutation, a central polypurine tract of HIV-1, a human cytomegalovirus and a composite intron from rabbit beta-globin. This transgenic strain was made by injecting the lentivirus vector containing the eGFP construct (lentiviral-CAG-eGFP) into SS rat embryos. 1642994 transgenic Rat Genome Database (RGD) RGD Unknown 1642994 2026-09-05 06:52:17 0
SS-Tg(CAG-eGFP)10Mcwi
 
Resource Report
Resource Website
RRID:RGD_1642995 Rattus norvegicus This transgenic strain contains the enhanced green fluorescent protein gene drived by ubiquitous CAG promoter. This vector contains long terminal repeats with self-inactivating mutation, a central polypurine tract of HIV-1, a human cytomegalovirus and a composite intron from rabbit beta-globin. This transgenic strain was made by injecting the lentivirus vector containing the eGFP construct (lentiviral-CAG-eGFP) into SS rat embryos. 1642995 transgenic Rat Genome Database (RGD) RGD Unknown 1642995 2026-09-05 06:52:17 0
SS-Tg(CAG-EGFP)28Mcwi
 
Resource Report
Resource Website
RRID:RGD_1642992 Rattus norvegicus This transgenic strain contains the enhanced green fluorescent protein gene drived by ubiquitous CAG promoter. This vector contains long terminal repeats with self-inactivating mutation, a central polypurine tract of HIV-1, a human cytomegalovirus and a composite intron from rabbit beta-globin. This transgenic strain was made by injecting the lentivirus vector containing the eGFP construct (lentiviral-CAG-eGFP) into SS rat embryos. 1642992 transgenic Rat Genome Database (RGD) RGD Unknown 1642992 2026-09-05 06:52:17 0

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