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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
http://www.taconic.com/transgenic-mouse-model/abb-knockouttransgenic-hla-dr4
Source Database: Taconic Biosciences
Affected Genes: histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: targeted mutation 1; Michael J Grusby
Availability: live
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1; mutant strain|congenic strain: H2-Ab1
Proper citation: RRID:IMSR_TAC:4149 Copy
Issue
https://www.jax.org/strain/035169
Source Database: JAX Mice and Services
Affected Genes: caudal type homeobox 2|Cre recombinase and estrogen receptor 1 (human) fusion gene|transgene insertion 752; Eric Fearon|APC; WNT signaling pathway regulator|Kras proto-oncogene; GTPase
Genomic Alteration: transgene insertion 752; Eric Fearon|targeted mutation 1; Tetsuo Noda|targeted mutation 4; Tyler Jacks
Availability: live
Synonyms: KPC:APC
Notes: gene symbol note: caudal type homeobox 2|Cre recombinase and estrogen receptor 1 (human) fusion gene|transgene insertion 752; Eric Fearon|APC; WNT signaling pathway regulator|Kras proto-oncogene; GTPase; mutant strain|congenic strain: CDX2|cre/ERT2|Tg(CDX2-cre/ERT2)752Erf|Apc|Kras
Proper citation: RRID:IMSR_JAX:035169 Copy
Issue
https://www.jax.org/strain/032435
Source Database: JAX Mice and Services
Affected Genes: transformation related protein 53|Kras proto-oncogene; GTPase
Genomic Alteration: targeted mutation 1; Anton Berns|targeted mutation 4; Tyler Jacks
Availability: live
Notes: gene symbol note: transformation related protein 53|Kras proto-oncogene; GTPase; mutant strain|congenic strain: Trp53|Kras
Proper citation: RRID:IMSR_JAX:032435 Copy
Issue
https://www.jax.org/strain/033964
Source Database: JAX Mice and Services
Affected Genes: phosphatase and tensin homolog|Kras proto-oncogene; GTPase|pancreas specific transcription factor; 1a|Cre recombinase and estrogen receptor 1 fusion gene
Genomic Alteration: targeted mutation 1; Hong Wu|targeted mutation 4; Tyler Jacks|targeted mutation 2; Christopher VE Wright
Availability: live
Synonyms: KPP
Notes: gene symbol note: phosphatase and tensin homolog|Kras proto-oncogene; GTPase|pancreas specific transcription factor; 1a|Cre recombinase and estrogen receptor 1 fusion gene; mutant strain|congenic strain: Pten|Kras|Ptf1a|cre/Esr1
Proper citation: RRID:IMSR_JAX:033964 Copy
Issue Issue
https://www.jax.org/strain/002479
Source Database: JAX Mice and Services
Affected Genes: interleukin 2 receptor; gamma chain
Genomic Alteration: targeted mutation 1; University of Cologne
Availability: embryo
Synonyms: STOCK Il2rg
Notes: gene symbol note: interleukin 2 receptor; gamma chain; mutant stock: Il2rg
Proper citation: RRID:IMSR_JAX:002479 Copy
Issue
https://www.jax.org/strain/002420
Source Database: JAX Mice and Services
Affected Genes: beta-2 microglobulin
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: sperm
Notes: gene symbol note: beta-2 microglobulin; mutant strain|congenic strain: B2m
Proper citation: RRID:IMSR_JAX:002420 Copy
Issue
https://www.jax.org/strain/002453
Source Database: JAX Mice and Services
Affected Genes: beta-2 microglobulin
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: embryo
Notes: gene symbol note: beta-2 microglobulin; mutant strain|congenic strain: B2m
Proper citation: RRID:IMSR_JAX:002453 Copy
Issue
https://www.jax.org/strain/002455
Source Database: JAX Mice and Services
Affected Genes: beta-2 microglobulin|Fas cell surface death receptor
Genomic Alteration: targeted mutation 1; University of North Carolina|lymphoproliferation
Availability: embryo
Synonyms: MRL-Tnfrsf6
Notes: gene symbol note: beta-2 microglobulin|Fas cell surface death receptor; mutant strain|congenic strain: B2m|Fas
Proper citation: RRID:IMSR_JAX:002455 Copy
Issue
https://www.jax.org/strain/002449
Source Database: JAX Mice and Services
Affected Genes: beta-2 microglobulin
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: embryo
Notes: gene symbol note: beta-2 microglobulin; mutant strain|congenic strain: B2m
Proper citation: RRID:IMSR_JAX:002449 Copy
Issue
https://www.jax.org/strain/002575
Source Database: JAX Mice and Services
Affected Genes: interferon gamma
Genomic Alteration: targeted mutation 1; Timothy Stewart
Availability: embryo
Notes: gene symbol note: interferon gamma; mutant strain|congenic strain: Ifng
Proper citation: RRID:IMSR_JAX:002575 Copy
Issue
https://www.jax.org/strain/002756
Source Database: JAX Mice and Services
Affected Genes: cadherin related 23 (otocadherin)
Genomic Alteration: wild-type of age related hearing loss
Availability: live
Synonyms: B6.CAST-Ahl<+>. B6.CAST-Cdh23
Notes: gene symbol note: cadherin related 23 (otocadherin); mutant strain|congenic strain: Cdh23
Proper citation: RRID:IMSR_JAX:002756 Copy
Issue
https://www.jax.org/strain/003329
Source Database: JAX Mice and Services
Affected Genes: integrin beta 2
Genomic Alteration: targeted mutation 2; Baylor College of Medicine
Availability: embryo
Notes: gene symbol note: integrin beta 2; mutant strain|congenic strain: Itgb2
Proper citation: RRID:IMSR_JAX:003329 Copy
Issue Issue
https://www.jax.org/strain/003243
Source Database: JAX Mice and Services
Affected Genes: tumor necrosis factor receptor superfamily; member 1b|tumor necrosis factor receptor superfamily; member 1a
Genomic Alteration: targeted mutation 1; Immunex Research and Development Corporation
Availability: sperm
Synonyms: B6.129S-Tnfrsf1a
Notes: gene symbol note: tumor necrosis factor receptor superfamily; member 1b|tumor necrosis factor receptor superfamily; member 1a; mutant strain|congenic strain: Tnfrsf1b|Tnfrsf1a
Proper citation: RRID:IMSR_JAX:003243 Copy
Issue
https://www.jax.org/strain/003355
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 55; Hidde Ploegh|beta-2-microglobulin|beta-2 microglobulin
Genomic Alteration: transgene insertion 55; Hidde Ploegh|targeted mutation 1; University of North Carolina
Availability: embryo
Notes: gene symbol note: transgene insertion 55; Hidde Ploegh|beta-2-microglobulin|beta-2 microglobulin; mutant strain|congenic strain: Tg(B2M)55Hpl|B2M|B2m
Proper citation: RRID:IMSR_JAX:003355 Copy
Issue
https://www.jax.org/strain/003238
Source Database: JAX Mice and Services
Affected Genes: class II transactivator
Genomic Alteration: targeted mutation 1; Cheong-Hee Chang
Availability: sperm
Synonyms: C.129S2(B6)-C2ta
Notes: gene symbol note: class II transactivator; mutant strain|congenic strain: Ciita
Proper citation: RRID:IMSR_JAX:003238 Copy
Issue
https://www.jax.org/strain/003556
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 1; University of Cologne|MX dynamin-like GTPase 1|
Genomic Alteration: transgene insertion 1; University of Cologne
Availability: live
Synonyms: C57BL/6J-Tg(Mx1-cre)1Cgn/J. C57BL/6J-TgN(Mx1-Cre)1Cgn
Notes: gene symbol note: transgene insertion 1; University of Cologne|MX dynamin-like GTPase 1|; mutant strain|congenic strain: Tg(Mx1-cre)1Cgn|Mx1|
Proper citation: RRID:IMSR_JAX:003556 Copy
Issue
https://www.jax.org/strain/003533
Source Database: JAX Mice and Services
Affected Genes: recessive spotting|beta-2 microglobulin
Genomic Alteration: recessive spotting 2 Jackson|targeted mutation 1; University of North Carolina
Availability: embryo
Notes: gene symbol note: recessive spotting|beta-2 microglobulin; mutant strain: rs|B2m
Proper citation: RRID:IMSR_JAX:003533 Copy
Issue
https://www.jax.org/strain/003653
Source Database: JAX Mice and Services
Affected Genes: glutamic acid decarboxylase 2
Genomic Alteration: targeted mutation 1; Steinunn Baekkeskov
Availability: sperm
Synonyms: NOD/LtJ-Gad2
Notes: gene symbol note: glutamic acid decarboxylase 2; mutant strain: Gad2
Proper citation: RRID:IMSR_JAX:003653 Copy
Issue
https://www.jax.org/strain/004088
Source Database: JAX Mice and Services
Affected Genes: forkhead box P3
Genomic Alteration: scurfy
Availability: embryo
Synonyms: B.Cg-Foxp3
Notes: gene symbol note: forkhead box P3; mutant strain|congenic strain: Foxp3
Proper citation: RRID:IMSR_JAX:004088 Copy
Issue
https://www.jax.org/strain/004671
Source Database: JAX Mice and Services
Affected Genes: signal transducer and activator of transcription 4
Genomic Alteration: targeted mutation 1; Michael J Grusby
Availability: embryo
Notes: gene symbol note: signal transducer and activator of transcription 4; mutant strain|congenic strain: Stat4
Proper citation: RRID:IMSR_JAX:004671 Copy
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