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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
SD.DA-Il2rgTm(G843D-FRT-CAG-Pac-FRT)1Qly Resource Report Resource Website |
RRID:RRRC_00845 | Rattus norvegicus | This strain was made by electroporation of DAc8 embryonic stem cells with a targeting vector containing 6.0kb 5' and 1.8kb 3' homology arms and a FRT-CAG-Pac-FRT cassette. The FRT-CAG-Pac-FRT cassette is inserted into the intron between Il2rg 4th and 5th exon. No genomic sequence is deleted. Chimeras were formed by microinjecting into F344 blastocysts. Founder animals were mated with SD rats to produce this strain. Rat Resource and Research Center | 00845 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695031, 14695031, RRRC_845, RRRC_0845, RRRC_00845 | 2026-09-05 02:46:55 | 0 | |||||
|
SD.DA-Pex1tm(G843D-FRT-CAG-Pac-FRT)1Qly Resource Report Resource Website |
RRID:RRRC_00846 | Rattus norvegicus | This strain was made by electroporation of DAc8 embryonic stem cells with a targeting vector containing 5.8kb 5' and 1.7kb 3' homology arms. A G843D point mutation is introduced into the Pex1 gene. The 12th and 13th exons are flanked with two loxP sites. A FRT-CAG-Pac-FRT cassette is inserted into the intron between Pex1 13th and 14th exon. This strain mimics the Peroxisomal Disorders. Heterozygote does not show any abnormalities. Rat Resource and Research Center | 00846 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695030, 14695030, RRRC_846, RRRC_0846, RRRC_00846 | 2026-09-05 02:46:55 | 0 | |||||
|
SD-Gfapem1Mes+/- Resource Report Resource Website 1+ mentions |
RRID:RRRC_00932 | Rattus norvegicus | The targeted mutation in the rat GFAP gene was based on the severity and frequency of the R239H mutation in human disease. The CRISPR/Cas9 system was used to mediated knockin of point mutation (R237H) to Sprague-Dawley embryos. The current background srain is Crl:CD (SD). This mutant strain serves as a model for Alexander disease. knockins have post-weaning failure to thrive and ~10% mortality by 12 weeks, but afterwards are viable and can breed . The strain is now deposited at Rat Resource and Research Center | 00932 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_598973845, 598973845, RRRC_932, RRRC_0932, RRRC_00932 | 2026-09-05 02:46:56 | 3 | |||||
|
SD-Artfm/Rrrc Resource Report Resource Website |
RRID:RRRC_00940 | Rattus norvegicus | This spontaneous mutant strain was originally derived from King Holtzman background and now maintained in Sprague Dawley background. A single nucleotide mutation was identified in the androgen receptor gene. The tfm males are sterile so the mutation is carried via females who breed normally. Rat Resource and Research Center | 00940 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150526809, 150526809, RRRC_940, RRRC_0940, RRRC_00940 | 2026-09-05 02:46:55 | 0 | |||||
|
SD-Lrp5em3Vari/Rrrc Resource Report Resource Website |
RRID:RRRC_00881 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce an inversion coupled with small deletions in the exon 2 at both the sgRNA1 (11 bp) and sgRNA2 sites (3 bp) in the rat Lrp5 gene of Crl:SD embryos. Rat Resource and Research Center | 00881 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521608, 150521608, RRRC_881, RRRC_0881, RRRC_00881 | 2026-09-05 02:46:55 | 0 | |||||
|
LE-ROSA26em1(LTR-nLuc)Ottc Resource Report Resource Website |
RRID:RRRC_00924 | Rattus norvegicus | The CRISPR/Case9 knock-in rats have cre recombinase-dependent expression of nanoluciferase under the control of HIV LTR promoter inserted to the rat ROSA26 locus. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center | 00924 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_13208223, 13208223, RRRC_924, RRRC_0924, RRRC_00924 | 2026-09-05 02:46:55 | 0 | |||||
|
LE-ROSA26 em1(CAG-Ghsr)Ottc Resource Report Resource Website |
RRID:RRRC_01022 | Rattus norvegicus | The CRISPR/Case9 knock-in of CAG-LSL-Ghsr (LSL: loxp-Stop-Loxp) to the ROSA 26 locus of LE rats has cre recombinase-dependent expression of rat Ghsr under the control of CAG promoter. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center | 01022 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo (as of 2025-08-29) | RGD_405100723, 405100723, RRRC_1022, RRRC_01022 | 2026-09-05 02:46:56 | 0 | |||||
|
SD-L1camem1Jgn Resource Report Resource Website |
RRID:RRRC_00850 | Rattus norvegicus | The CRISPR/Cas9 genome editing system was used to generate L1cam mutation in the Sprague Dawley embryos. The CRISPR/Cas9 targeting exon 4 of the rat L1cam created a 1bp-insertion (206_207insT) in exon 4. No protein expression was detected in the brain. Rat Resource and Research Center | 00850 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695002, 14695002, RRRC_850, RRRC_0850, RRRC_00850 | 2026-09-05 02:46:55 | 0 | |||||
|
SD-L1camem2Jgn Resource Report Resource Website |
RRID:RRRC_00851 | Rattus norvegicus | The CRISPR/Cas9 genome editing system was used to generate L1cam mutation in the Sprague Dawley embryos. The CRISPR/Cas9 targeting exon 4 of the rat L1cam created a 300 bp-deletion(c.205_505del) in exon 4. No protein expression was detected in the brain. Rat Resource and Research Center | 00851 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695003, 14695003, RRRC_851, RRRC_0851, RRRC_00851 | 2026-09-05 02:46:55 | 0 | |||||
|
SD-Trim63em1(hiLuc)/Rrrc Resource Report Resource Website |
RRID:RRRC_00731 | Rattus norvegicus | The use of zinc finger nuclease technology (ZFN) to knockin a luciferase reporter directly downstream of MuRF1 (Trim63) coding sequences in rats,leaving endogenous MuRF1 gene expression intact and bicistro-nically linking it to the inserted reporter through a hepatitis CIRES (HCV-IRES). The resulting knockin rat line, MuRF1-hiLUCs, has reporter characteristics that are fully reflective ofendogenous MuRF1 gene expression, can be used as a universalbiomarker of skeletal muscle atrophyin vivo, and has abioluminescent readout compatible with whole animal imagingmodalities. Rat Resource and Research Center | 00731 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695085, 14695085, RRRC_731, RRRC_0731, RRRC_00731 | 2026-09-05 02:46:55 | 0 | |||||
|
SD-Sdhbem1Ast Resource Report Resource Website |
RRID:RRRC_00853 | Rattus norvegicus | This mutant strain was generated by injecting TALEN targeting rat Sdhb into NTac:SD embryo. The resulting mutant is a 4 bp-deletion in Sdhb. Rat Resource and Research Center | 00853 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14694998, 14694998, RRRC_853, RRRC_0853, RRRC_00853 | 2026-09-05 02:46:55 | 0 | |||||
|
SD-Sdhbem3Ast Resource Report Resource Website |
RRID:RRRC_00855 | Rattus norvegicus | This mutant strain was generated by injecting TALEN targeting rat Sdhb into NTac:SD embryo. The resulting mutant is a 15 bp-deletion in Sdhb. Rat Resource and Research Center | 00855 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695000, 14695000, RRRC_855, RRRC_0855, RRRC_00855 | 2026-09-05 02:46:55 | 0 | |||||
|
SD-Abca4em1Tuckr Resource Report Resource Website |
RRID:RRRC_01035 | Rattus norvegicus | The rat Abca4 gene (Gene ID: 310836; GenBank accession number: NM_001107721.1) is located on rat chromosome 2. Exon 2 to exon 8 were selected as the target site for CRISPR/Cas9 modification on Sprague Dawley embryos. Rat Resource and Research Center | 01035 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Live Animals (as of 2025-07-16) | RGD_617212698, 617212698, RRRC_1035, RRRC_01035 | 2026-09-05 02:46:56 | 0 | |||||
|
SD-Pgrem1Soar Resource Report Resource Website 1+ mentions |
RRID:RRRC_00741 | Rattus norvegicus | Crispr/Cas9 targeting of Exon 3 of rat Pgr gene resulting in a deletion of Exon3 Rat Resource and Research Center | 00741 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11081142, 11081142, RRRC_741, RRRC_0741, RRRC_00741 | 2026-09-05 02:46:54 | 1 | |||||
|
SD-Cftrem1Wpick Resource Report Resource Website |
RRID:RRRC_01038 | Rattus norvegicus | A targeted 16 bp deletion was made in Exon 3 of the rat Cftr gene using CRISPR-Cas9 technology. Rat Resource and Research Center | 01038 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Live Animals (as of 2025-03-18) | RGD_598092487, 598092487, RRRC_1038, RRRC_01038 | 2026-09-05 02:46:55 | 0 | |||||
|
WI-Grm8em1Geh Resource Report Resource Website |
RRID:RRRC_00744 | Rattus norvegicus | CRISPR/Cas9 induced 29 base pair deletion in exon 1 Rat Resource and Research Center | 00744 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11081151, 11081151, RRRC_744, RRRC_0744, RRRC_00744 | 2026-09-05 02:46:55 | 0 | |||||
|
WI-Htr7em1Geh Resource Report Resource Website |
RRID:RRRC_00745 | Rattus norvegicus | CRISPR/Cas9 system was used to generate this mutant; this induced 89 base pair deletion in exon 1 of the Htr7 gene. Rat Resource and Research Center | 00745 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm; Cryorecovery | RGD_11040561, 11040561, RRRC_745, RRRC_0745, RRRC_00745 | 2026-09-05 02:46:55 | 0 | |||||
|
SD-Lrp5em1Vari/Rrrc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00867 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 18-bp deletion of exon 2 in the rat Lrp5 gene of Crl:SD embryos. Rat Resource and Research Center | 00867 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521610, 150521610, RRRC_867, RRRC_0867, RRRC_00867 | 2026-09-05 02:46:55 | 1 | |||||
|
SD-Phlda2em1Soar Resource Report Resource Website |
RRID:RRRC_01048 | Rattus norvegicus | Crispr/Cas9 mediated 103 bp deletion within Exon 1 of the Phlda2 gene Rat Resource and Research Center | 01048 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Live Animals (as of 2025-09-15) | RGD_626469555, 626469555, RRRC_1048, RRRC_01048 | 2026-09-05 02:46:56 | 0 | |||||
|
SD-Foxn1rnuTg((Rho-S334X)3,CAG-tdTomato)1010Mjsuc Resource Report Resource Website 1+ mentions |
RRID:RRRC_01055 | Rattus norvegicus | Embryos from “SD-Foxn1rnuTg(Rho-S334X)3LavRrrc (RGD: 626189117)”, citation ID:RRID:RRRC_00539, were injected with the plasmid gene construct floxed TdTomato created by Envigo, coupled to the universal CAG promoter Rat Resource and Research Center | 01055 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Live Animals (as of 2025-09-03) | RGD_626189121, 626189121, RRRC_1055, RRRC_01055 | 2026-09-05 02:46:56 | 1 |
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