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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5508365
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: 5508365
Notes: This strain was produced by injecting ZFNs targeting the sequence CTTTGCCCCTGTGGGCAGtctatACCGCTATGGAGTACCGCT into SS/JrHsdMcwi rat embryos. The resulting mutation is a 19-bp frameshift deletion in exon 3.
Proper citation: RRID:RGD_5508365 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5508366
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct
Alternate IDs: 5508366
Notes: This strain was produced by injecting ZFNs targeting the sequence GTCTGAGTTTACcaatgcGAGTAACCATCTGGCAGCT into SS/JrHsdMcwi rat embryos. The resulting mutation is a 16-bp frameshift deletion in exon 6.
Proper citation: RRID:RGD_5508366 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5508367
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: 5508367
Notes: This strain was produced by injecting ZFNs targeting the sequence CTACCTTGTAGCTACccaggtGAGGCTGTCTGATGAA into SS/JrHsdMcwi rat embryos. The resulting mutation is a 14-bp deletion in exon 15 and intron 15
Proper citation: RRID:RGD_5508367 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5508369
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct (as of 2017-01-26)
Alternate IDs: 5508369
Notes: This strain was produced by injecting ZFNs targeting the sequence CTGATGGGCAGCACCATGgaccccCCGGGGGGTGCA into SS/JrHsdMcwi rat embryos. The resulting mutation is a 13-bp frameshift deletion in exon 1.
Proper citation: RRID:RGD_5508369 Copy
The record is no longer available at this source.
Source Database: RGD, Rat Genome Database Strain List RGD
Genetic Background: mutant
Affected Genes: (null)
Genomic Alteration: (null)
Availability: Not Available
Source References: (null)
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Nlrp3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 14-bp deletion of exon 1 in the Nlrp3 gene. MCW Gene Editing Rat Resource Center This is a legacy resource.
Proper citation: RRID:RGD_12790673 Copy
The record is no longer available at this source.
Source Database: RGD, Rat Genome Database Strain List RGD
Genetic Background: mutant
Affected Genes: (null)
Genomic Alteration: (null)
Availability: Not Available
Source References: (null)
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Nlrp3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 10-bp deletion of exon 1 in the Nlrp3 gene. MCW Gene Editing Rat Resource Center This is a legacy resource.
Proper citation: RRID:RGD_12790669 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=401900749
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2023-11-21)
Alternate IDs: RGD_401900749
Notes: CRISPR/Cas9 system was used to introduce a 272 bp deletion at the Prl7b1 locus Rat Resource and Research Center
Proper citation: 001014 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=617212698
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Live Animals (as of 2025-07-16)
Alternate IDs: RGD_617212698
Notes: The rat Abca4 gene (Gene ID: 310836; GenBank accession number: NM_001107721.1) is located on rat chromosome 2. Exon 2 to exon 8 were selected as the target site for CRISPR/Cas9 modification on Sprague Dawley embryos. Rat Resource and Research Center
Proper citation: 001035 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=598092487
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Live Animals (as of 2025-03-18)
Alternate IDs: RGD_598092487
Notes: A targeted 16 bp deletion was made in Exon 3 of the rat Cftr gene using CRISPR-Cas9 technology. Rat Resource and Research Center
Proper citation: 001038 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290082
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290082, 2290082, RRRC_425, RRRC_0425, RRRC_00425
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 7th intron of the Brinp3 gene. Rat Resource & Research Center
Proper citation: RRID:RRRC_00425 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290166
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290166, 2290166, RRRC_424, RRRC_0424, RRRC_00424
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 18th exon of the Plcb3 gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00424 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290056
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290056, 2290056, RRRC_423, RRRC_0423, RRRC_00423
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 4th intron of the Rbed1 gene. Rat Resource & Research Center
Proper citation: RRID:RRRC_00423 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1642364
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_1642364, 1642364, RRRC_421, RRRC_0421, RRRC_00421
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. N26K mutation is generated from the codon change AAC/AAA. Rat Resource and Research Center
Proper citation: RRID:RRRC_00421 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290113
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290113, 2290113, RRRC_387, RRRC_0387, RRRC_00387
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the Fam19a2 gene. Rat Resource & Research Center
Proper citation: RRID:RRRC_00387 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2292451
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2292451, 2292451, RRRC_386, RRRC_0386, RRRC_00386
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the Stxbp5l gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00386 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290078
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_2290078, 2290078, RRRC_385, RRRC_0385, RRRC_00385
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 8th intron of the Myo9a gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00385 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=153298963
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_153298963, 153298963, RRRC_963, RRRC_0963, RRRC_00963
Notes: These mutants were found in Sprague-Dawley rats at University of Puebla in 1989 and donated by John Svaren to RRRC now are maintained at RRRC Rat Resource and Research Center
Proper citation: RRID:RRRC_00963 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1642439
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_1642439, 1642439, RRRC_419, RRRC_0419, RRRC_00419
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. Y297Stop mutation is generated from the codon change TAC/TAA. Rat Resource and Research Center
Proper citation: RRID:RRRC_00419 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1642276
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_1642276, 1642276, RRRC_418, RRRC_0418, RRRC_00418
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. N152K mutation is generated from the codon change AAT/AAA. Rat Resource and Research Center
Proper citation: RRID:RRRC_00418 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1642277
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_1642277, 1642277, RRRC_416, RRRC_0416, RRRC_00416
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. F475L mutation is generated from the codon change TTC/CTC. Rat Resource and Research Center
Proper citation: RRID:RRRC_00416 Copy
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