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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=39128239
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 39128239
Notes: The Goto-Kakizaki (GK) rat is a non-obese Wistar substrain which develops Type 2 diabetes mellitus early in life. The model was developed by Goto and Kakizaki at Tohoku University, Sendai, Japan in 1975. To Chugai Pharmaceutical Co. To Charles River Japan in 1995. Charles River Laboratories Japan
Proper citation: RRID:RGD_39128239 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=127284837
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 127284837
Notes: The Goto-Kakizaki (GK) rat is a non-obese Wistar substrain which develops Type 2 diabetes mellitus early in life. The model was developed by Goto and Kakizaki at Tohoku University, Sendai, Japan in 1975. The GK line was established by repeated inbreeding from Wistar rats selected at the upper limit of normal distribution for glucose tolerance. Repeated selection of rats with tendency to lowest glucose tolerance resulted in clear-cut glucose intolerance after five generations. This GK/Wnsm colony was established at the University of Wales College of Medicine (Cardiff, UK) after received breeding
pairs provided by Professor Y Goto (Tohoku University School of Medicine, Sendai, Japan).
Proper citation: RRID:RGD_127284837 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=21409748
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 21409748
Notes: Dark Agouti rats which were bred and housed at the Military Medical Academy in Belgrade, Serbia
Proper citation: RRID:RGD_21409748 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=40924649
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 40924649
Notes: Nine inbred lines developed from random-bred colony maintained by B. Houssay since 1948. Inbreeding and upward selection of body weight and fertility were performed in every line. Groups of rats from lines 'b' were separated in 1958 and raised at the School of Medicine at Rosario. In 1976, some degree of overweight was found in the original 'b' group and in 1980, the obesity group was identified as Beta line.
Proper citation: RRID:RGD_40924649 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=38549341
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 38549341
Notes: Muhlbock, Amsterdam, 1947, from Wistar stock. To University of Leiden in 1958. To Erasmus University, Rotterdam in 1968. To Rijswick in 1982 (Greenhouse et al 1991). To Harlan (?).
Proper citation: RRID:RGD_38549341 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=38549352
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals; Cryopreserved Embryo (as of 2024-08-06)
Alternate IDs: 38549352
Notes: These are re-derived rats of SHR substrain (SHR/OlaIpcv, RGD:9586450) from Czech Academy of Sciences now maintained at Medical College of Wisconsin. RGD HRDP, contact Hybrid Rat Diversity Program at
[email protected]
Proper citation: RRID:RGD_38549352 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=126848763
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals (as of 2021-04-29)
Synonyms: , wild type
Alternate IDs: 126848763
Notes: This is the wild type control for ODS-Gulood/od/ShiJcl (RGD:4140404) . Dr. Susumu Makino and his colleagues found several animals that had gait abnormalities among Wistar rats maintained at Shionogi Co. They named these animals osteogenic disorder (OD) rats because they exhibited prominent bone and joint abnormalities and systemic bleeding. Subsequent studies revealed that these symptoms were derived from an ascorbic acid (vitamin C) deficiency arising from defective gulonolactone oxidase (GLO) activity. This characteristic was confirmed to be the result of a mutation involving the autosomal single recessive gene od. Scurvy due to L-gulonolactone oxidase deficincy; phenotype normalizes if supplied with ascorbic acid 300mg/kg/d. od/od rats are more susceptible to dental caries as compared with +/+ rats, in only amoun parous females. CLEA Japan, Inc
Proper citation: RRID:RGD_126848763 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=127338474
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 127338474
Notes: This strain was maintained in Germany and was transferred to Japan by Dr. Tanaka of Aichi Cancer Center. Thereafter, this strain was transferred to Research Institute of Environmental Medicine, Nagoya University in 1973
Proper citation: RRID:RGD_127338474 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60985
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 60985
Notes: Billingham and Silvers 1958, from a brown mutation maintained by DH King and P Aptekman in a pen-bred colony (Billingham and Silvers 1959). A plasma kininogen-deficient mutant strain (BN/Ka) has been described in which release of heat-induced substance P is defective (Tang et al, 1994) and response to the hypertensive effects of deoxycorticosterone acetate salt is much faster than in normal BN rats (Majima et al, 1995a,b). Charles River Laboratories
Proper citation: RRID:RGD_60985 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60988
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 60988
Notes: Bazin and Beckers from rats of presumed Wistar origin kept at the Universite Catholique de Louvain. LOU/C was selected among 28 parallel sublines for its high incidence of plasmacytomas, and LOU/M for its low incidence. The two are histocomaptible. Histocompatible with LOU/C and maintained by selection of LOU/M males on the basis of acceptance of skin grafts from LOU/C rats (Bazin 1977, Beckers and Bazin 1978).
Proper citation: RRID:RGD_60988 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60989
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 60989
Notes: Strain selected for resistance to Walker 256 tumour.
Proper citation: RRID:RGD_60989 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1598798
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Extinct (as of 2021-02-22)
Alternate IDs: 1598798
Notes: Diabetes prone BB rats maintained in NIH. Developed from a closed colony of outbred wistar rats which spontaneously developed autoimmune diabetes mellitus at the Bio-Breeding Laboratories, Ontario. University of Massachusetts Medical Center started inbreeding these in 1977. In 1983 NIH established a reference colony from this inbred colony.
Proper citation: RRID:RGD_1598798 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10008
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10008
Notes: Obtained by HSD from nucleus colony at NIH Harlan
Proper citation: RRID:RGD_10008 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10009
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10009
Proper citation: RRID:RGD_10009 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10006
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10006
Notes: Druckrey from F2 offspring of a cross between BDVI and BDI with subsequent selection of brother-sister pairs for a pink-eyed, yellow, blackhooded phenotype.
Proper citation: RRID:RGD_10006 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10001
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10001
Proper citation: RRID:RGD_10001 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10004
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10004
Notes: Obtained from the Central Laboratory Animal Institute of Utrecht University, The Netherlands.
Proper citation: RRID:RGD_10004 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10043828
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2024-09-24)
Alternate IDs: 10043828
Notes: Spontaneously hypertensive rat (SHR) was segregated in Wistar-Kyoto rat in 1963. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_10043828 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10005
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10005
Notes: unknown
Proper citation: RRID:RGD_10005 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10002
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10002
Notes: S. Bieg and coworkers (1998) generated a congenic line in which diabetes and lymphopenia are controlled solely by Iddm 1. This strain was generated by nine cycles of cross-intercross breeding of diabetes-prone DP with DR BB rats. Iddm 1 in the BioBreeding (BB) rat designates the genomic region on rat Chromosome (Chr) 4 that harbors the gene causing peripheral T cell lymphopenia (Lyp) and diabetes. The average age of onset of diabetes was 85 ± 53 days of age after the first and 67 ± 10 days of age after the 9th cycle.
Proper citation: RRID:RGD_10002 Copy
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