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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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SD-Shank3em1Bcgen Resource Report Resource Website |
RRID:RGD_631721277 | Rattus norvegicus | The mutant rats were generated using CRISPR/Cas9 technology to target upstream of exon 11 or downstream of exon 21 of rat Shank3. The resulting mutant carried approximately 26 kb deletions with the removal of the Shank3 exon 11–21 [email protected] at Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, China | 631721277 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 631721277 | 2026-09-05 06:52:47 | 0 | |||||
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SD-Ager em1Mcwi Resource Report Resource Website |
RRID:RGD_152998995 | Rattus norvegicus | This model was generated at the Medical College of Wisconsin by CRISPR/Cas9 in Crl:SD strain. The resulting mutation is a 16-bp deletion in the third exon of Ager. rn6.0:chr20:4,150,397-4,150,412. contact MCW Rat Distribution at [email protected] | 152998995 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2022-07-15) | 152998995 | 2026-09-05 06:52:47 | 0 | |||||
|
CD-Dmdem1Gene+/+ Resource Report Resource Website |
RRID:RGD_629142769 | Rattus norvegicus | The is the wild type litter mate for the Dmd mutant: CD-Dmdem1Gene (RGD:629142768), Genethon; 1, bis rue de l’internationale23 91000 Evry, France | 629142769 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 629142769 | 2026-09-05 06:52:47 | 0 | |||||
|
CD-Dmdem1Gene Resource Report Resource Website |
RRID:RGD_629142768 | Rattus norvegicus | The model was generated using a single guide RNA-Cas9 targeted to exon 45 of the rat Dmd gene on a Sprague-Dawley (CD®(SD), Crl:CD(SD)) background. One male founder with a 606 bp deletion encompassing Dmd exon 45 and spanning from 207 bp into the 3’ region of intron 44 to 223 bp into the 5’ region of intron 45,including exon 45, was selected for phenotyping. The heterozygous/hemizygous Dmd knock-out lines were used for breeding. Genethon; 1, bis rue de l’internationale23 91000 Evry, France | 629142768 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 629142768 | 2026-09-05 06:52:47 | 0 | |||||
|
SD-Slc5a9em1Mcwi Resource Report Resource Website |
RRID:RGD_617301241 | Rattus norvegicus | Crl:SD embryos were injected with CRISPR-Cas9 using guide RNA targeting the sequence AGGTCATGGATCTTCCAGCC. A 4-bp deletion in exon 2 (rn7: chr5:126,730,986-126,730,989) resulted. Dr. Noreen Rossi, Contact Email: [email protected] | 617301241 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2025-07-28) | 617301241 | 2026-09-05 06:52:47 | 0 | |||||
|
SD-CdCSem1Bcgen+/- Resource Report Resource Website |
RRID:RGD_616390066 | Rattus norvegicus | To generate the 5p15.2 deletion in the rat, two CRISPR gRNAs were designed at syntenic loci in the rat genome: ATGTCGATGTCTTGTTAGGGTGG at Chr.2:83120000 (RGSC 6.0/rn6) and GCTGAGATGGCTTTCAGAAATGG at Chr.2:84800000 (RGSC 6.0/rn6), which induced ≈1.68 Mb chromosomal deletion. The Biocytogen Transgenic and Gene Targeting core injected 50 ng uL−1 of each gRNAs and 100 ng uL−1 Cas9 RNA into single‐cell SD rat zygotes. Embryos were cultured overnight and transferred to pseudopregnant females. PCR was used to screen for the deletion. PCR was performed using genomic ear or tail DNA, and the following primer pair: Proximal Forward‐TTGCTCAGCTGTTAAGGGAAACTAT and Distal Reverse‐TCATCAAAATGCACCAAAAGTGCAA (these primers generate ≈485 bp product). PCR primers were used to detect the breakpoint on the undeleted 5p15.2 interval (wild‐type allele): Proximal Forward‐TTGCTCAGCTGTTAAGGGAAACTAT and Proximal Reverse‐GGAGTAAGTCAACTGACTAGGGGACA (these primers generate ≈618 bp product). | 616390066 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 616390066 | 2026-09-05 06:52:47 | 0 | |||||
|
SD-Slc5a10em1Mcwi Resource Report Resource Website |
RRID:RGD_617301243 | Rattus norvegicus | Crl:SD embryos were injected with CRISPR-Cas9 using guide RNA targeting the sequence GAATACATTCAGAAGCGCTT. A 29-bp deletion in exon 5 (rn7: chr10:46,393,272-46,393,300) resulted. Dr. Noreen Rossi, Contact Email: [email protected] | 617301243 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2025-07-28) | 617301243 | 2026-09-05 06:52:47 | 0 | |||||
|
LE-Grin2aem1Sidb Resource Report Resource Website |
RRID:RGD_626170601 | Rattus norvegicus | In collaboration with Horizon Discovery, we generated a CRISPR/Cas9-mediated deletion of a 1065bp region spanning Grin2a exon 8 (which encodes key pore forming domains of GluN2A) in Long Evans (LE) embryos, generating a KO allele. Simons Initiative for the Developing Brain (SIDB), Institute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh EH8 9XD, UK. Contact SIDB Scientific Officer for enquiries on rat distribution ([email protected]). | 626170601 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2025-09-02) | 626170601 | 2026-09-05 06:52:47 | 0 | |||||
|
SD-Slc6a9em1(cre)Mira Resource Report Resource Website |
RRID:RGD_629116668 | Rattus norvegicus | The knock-in rat line was engineered to express the iCRE recombinase under the SLC6A9 locus. It was generated in SD background and maintain in this background for many generations. Rat Resource and Research Center | 629116668 | mutant | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2025-12-09) | 629116668 | 2026-09-05 06:52:47 | 0 | |||||
|
SD-Del(Sult1a1-Spn)/YahIcsOrl Resource Report Resource Website |
RRID:RGD_626168268 | Rattus norvegicus | Deletion of the genetic interval Sult1a1-Spn of Sprague Dawley rat: we targeted an extended sequence of the whole locus from one allele and the CRISPR/Cas9 system allowed us to remove the region encompassing 28 genes, orthologous to human. European Mouse Mutant Archive(EMMA) | 626168268 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo; Cryorecovery (as of 2025-08-29) | 626168268 | 2026-09-05 06:52:47 | 0 | |||||
|
SS-Rrg2em1Mcwi Resource Report Resource Website |
RRID:RGD_629142772 | Rattus norvegicus | Cas9 and sgRNA targeting the sequence GCTTTGCAACTTGTGCAGCA were injected into SS embryos to mutate a CTCF binding site within the first intron of Golt1a. a 3-bp deletion rn6 chr13:50,545,341-50,545,343 resulted. Custom Rats at Medical College of Wisconsin, Email: [email protected] | 629142772 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2025-12-30) | 629142772 | 2026-09-05 06:52:47 | 0 | |||||
|
SS-Rrg3em1Mcwi Resource Report Resource Website |
RRID:RGD_629142773 | Rattus norvegicus | Cas9 and sgRNA targeting the sequence GGGCATCTTCTGCCACCTAC were injected into SS embryos to mutate a CTCF binding site within the first intron of Ren. An 11-bp deletion rn6 chr13:50,509,649-50,509,659 resulted. Custom Rats at Medical College of Wisconsin, Email: [email protected] | 629142773 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2025-12-30) | 629142773 | 2026-09-05 06:52:47 | 0 | |||||
|
SD-Tbx21em1Sage Resource Report Resource Website |
RRID:RGD_626469804 | Rattus norvegicus | This is a Tbx21 knockout rat created using ZFN technology targeting exon 1 coding sequences 378-412. The resulting mutation is a 22-bp deletion (392-413). Inotiv | 626469804 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2025-09-17) | 626469804 | 2026-09-05 06:52:47 | 0 | |||||
|
SD-Oxtrem1(cre)Grin Resource Report Resource Website |
RRID:RGD_632517841 | Rattus norvegicus | CRISPR/Cas9-mediated knock-in of an IRES-Cre cassette into the 3' UTR of the endogenous Oxtr gene. The line is maintained in the heterozygous state and preserves normal Oxtr expression. Availability Contact Email: [email protected],Central Institute of Mental Health | 632517841 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2026-01-28) | 632517841 | 2026-09-05 06:52:47 | 0 | |||||
|
SS-Del(2q)1Mcwi +/+ Resource Report Resource Website |
RRID:RGD_617148292 | Rattus norvegicus | Four single guide RNAs and SpCas9 targeting sequences ATGAAGTGCCTAGCTTCATT, GAAGCTAGGCACTTCATCTA, ATTCATAATGGGACACTCGA, and CCCAGCCTCAGATTCATAAT flanking a chromosome 2 region distal to Npr3 were targeted in SS/JrHsdMcwi embryos. A 29,508 bp deletion in chromosome 2 (rn6: chr2:61,845,176-61,874,684) resulted, along with an insertion of 3 nucleotides (TGG). Please contact: [email protected] | 617148292 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2025-07-07) | 617148292 | 2026-09-05 06:52:47 | 0 | |||||
|
SD-Gnalem2Hpng Resource Report Resource Website |
RRID:RGD_626419677 | Rattus norvegicus | Gnal knockout rats were generated by CRISPR/Cas9 technology. Exon1 of rat Gnal splicing variant 2 was targeted, resulting in a deletion of 1 base pair that corresponds to position 44 downstream of the translation start point ATG of the Gnal splicing variant 2. CRISPR technology details: self-synthesized Cas9 mRNA using px 330 vector, applying T7 transcription kit followed by Poly-Adenylation and Capping. No sequencing performed, whether Cas9 has been inserted into the rat genome is unknown. Homozygous: Approximately 25% body weight reduction; Smaller body size; Hyperactivity; Better rotarod performance than wild-type littermates.Heterozygous: No body weight change; No body size change; Hypo-activity; Worse rotarod performance than wild-type littermates. European Mouse Mutant Archive(EMMA) | 626419677 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2025-09-05) | 626419677 | 2026-09-05 06:52:47 | 0 | |||||
|
LE-Syngap1em1Sidb Resource Report Resource Website |
RRID:RGD_626170599 | Rattus norvegicus | This KO allele was generated by Sigma Advanced Genetic Engineering (SAGE) Labs (St. Louis, MO, US) by injecting CRISPR/Cas9 reagents and sgRNA targeting exon 8 (gtgcatagagcatgtcgtccAGG) into Long Evans (LE) zygotes. Founder #23 displayed a 2bp deletion and 1bp insertion, leading to a frameshift mutation in exon 8 of Syngap1, which prevents expression of the protein. Homozygous Syngap1 KO rats die perinatally, but heterozygous Syngap1 KO rats appear healthy and are fertile. Simons Initiative for the Developing Brain (SIDB), Institute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh EH8 9XD, UK. Contact SIDB Scientific Officer for enquiries on rat distribution ([email protected]). | 626170599 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2025-09-02) | 626170599 | 2026-09-05 06:52:47 | 0 | |||||
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LE-Drd2em1(Cre)Rrrc Resource Report Resource Website |
RRID:RGD_629020173 | Rattus norvegicus | The Cre recombinase gene was knocked into exon 2 of the Drd2 gene using CRISPR/Cas9 genome editing. RRRC:00979 | 629020173 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 629020173 | 2026-09-05 06:52:47 | 0 | |||||
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LE-Csf1rem1Prdns Resource Report Resource Website |
RRID:RGD_626168248 | Rattus norvegicus | The CRISPR/Cas9 system was used to delete the FIRE ( Fms intronic regulatory element) enhancer of the Csf1r gene of LE rat embryos Clare Pridans Centre for Inflammation Research Institute for Regeneration and Repair The University of Edinburgh | 626168248 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2025-08-28) | 626168248 | 2026-09-05 06:52:47 | 0 | |||||
|
LE-ROSA26 em1(CAG-Ghsr)Ottc Resource Report Resource Website |
RRID:RGD_405100723 | Rattus norvegicus | The CRISPR/Case9 knock-in of CAG-LSL-Ghsr (LSL: loxp-Stop-Loxp) to the ROSA 26 locus of LE rats has cre recombinase-dependent expression of rat Ghsr under the control of CAG promoter. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. | 405100723 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 405100723 | 2026-09-05 06:52:47 | 0 |
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