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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00055068
Source Database: WormBase (WB)
Affected Genes: WBGene00001446(flp-3)
Genomic Alteration: WBGene00001446(flp-3)
Availability: unknown
Source References: PMID:37935195
Synonyms: flp-3(syb2634[flp-3::T2A::3XNLS::GFP]) X.
Notes: GFP tag inserted at the C-terminus of the endogenous flp-3 locus by CRISPR. Allele generated by SUNY Biotech. Please contact Oliver Hobert prior to publishing work using this strain.|"GFP tag inserted at the C-terminus of the endogenous flp-3 locus by CRISPR. Allele generated by SUNY Biotech. Reference: Tekieli T. et al. Development. 2021 Sep 15;148(18):dev199687. doi: 10.1242/dev.199687. PMID: 34415309."|"Made_by: Suny Biotech"|"Supplementary_genotype flp-3(syb2634[flp-3::T2A::3XNLS::GFP]) X"
Proper citation: RRID:WB-STRAIN:WBStrain00055068 Copy
http://www.wormbase.org/db/get?name=WBStrain00055103
Source Database: WormBase (WB)
Affected Genes: WBGene00003761(nlp-23)
Genomic Alteration: WBGene00003761(nlp-23)
Availability: unknown
Source References: EMPTY
Synonyms: nlp-23(syb3288[nlp-23::T2A::3xNLS::GFP]) X.
Notes: Endogenous locus tagged with T2A::3xNLS::GFP using CRISPR/Cas9. Please contact Oliver Hobert prior to publishing work using this strain.|"Made_by: Suny Biotech"
Proper citation: RRID:WB-STRAIN:WBStrain00055103 Copy
http://www.wormbase.org/db/get?name=WBStrain00055065
Source Database: WormBase (WB)
Affected Genes: WBGene00001454(flp-11)|WBGene00006672(twk-18)
Genomic Alteration: WBGene00001454(flp-11), WBGene00006672(twk-18)
Availability: unknown
Source References: EMPTY
Synonyms: flp-11(syb2193[flp-11::SL2::mKate2::linker::twk-18(e1913)]) X.
Notes: Made_by: Bringmann lab|"twk-18(e1913) was knocked into the endogenous locus of flp-11 to express a potassium channel in RIS that causes very strong inactivation of RIS. Reference: Busack I & Bringmann H. PLOS Genetics 19(3): e1010665. https:"
Proper citation: RRID:WB-STRAIN:WBStrain00055065 Copy
http://www.wormbase.org/db/get?name=WBStrain00055100
Source Database: WormBase (WB)
Affected Genes: WBGene00001456(flp-13)
Genomic Alteration: WBGene00001456(flp-13)
Availability: unknown
Source References: EMPTY
Synonyms: flp-13 (syb3277 [flp-13::T2A::3XNLS::GFP]) IV.
Notes: GFP tag inserted at the C-terminus of the endogenous flp-13 locus by CRISPR. Allele generated by SUNY Biotech. Please contact Oliver Hobert prior to publishing work using this strain.|"Made_by: Suny Biotech"
Proper citation: RRID:WB-STRAIN:WBStrain00055100 Copy
http://www.wormbase.org/db/get?name=WBStrain00055066
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00001454(flp-11)|WBGene00017389(lgc-38)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001454(flp-11), WBGene00017389(lgc-38)
Availability: unknown
Source References: EMPTY
Synonyms: lgc-38(syb2346[flp-11p::dpy-10 site::flp-11 3UTR] syb2493[ReaChR::linker::mKate2]) III.
Notes: Made_by: Bringmann lab|"ReaChR expressed in RIS for optogenetic activation. Reference: Busack I & Bringmann H. PLOS Genetics 19(3): e1010665. https:"
Proper citation: RRID:WB-STRAIN:WBStrain00055066 Copy
http://www.wormbase.org/db/get?name=WBStrain00055106
Source Database: WormBase (WB)
Affected Genes: WBGene00001454(flp-11)
Genomic Alteration: WBGene00001454(flp-11)
Availability: unknown
Source References: EMPTY
Synonyms: flp-11b(syb3317[flp-11b::T2A::3XNLS::GFP]) X
Notes: CRISPR/Cas9 engineered tagged endogenous locus.|"CRISPR/Cas9 engineered tagged endogneous locus."|"Made_by: Suny Biotech"
Proper citation: RRID:WB-STRAIN:WBStrain00055106 Copy
http://www.wormbase.org/db/get?name=WBStrain00055105
Source Database: WormBase (WB)
Affected Genes: WBGene00000403(casy-1)
Genomic Alteration: WBGene00000403(casy-1)
Availability: unknown
Source References: EMPTY
Synonyms: casy-1(syb3311[casy-1::gfp11x7]) II.
Notes: Made_by: SunyBiotech|"Split-GFP tag inserted into endogenous casy-1 locus by SunyBiotech using CRISPR/Cas9 with two guide RNAs simultaneously. Reference: Ding C, et al. Elife. 2022 Mar 14;11:e73557. PMID: 35285800."|"syb3311 created by the insertion of a tandem array containing seven copies of the GFP11 beta-strand (gfp11x7) in the endogenous casy-1 locus; can be crossed with reporter lines expressing the complementing split GFP fragment (gfp1-10) in specific cell types to facilitate tissue-specific labeling. Split-GFP tag inserted into endogenous casy-1 locus using CRISPR/Cas9 with two guide RNAs simultaneously. Reference: Ding C, et al. Elife. 2022 Mar 14;11:e73557. PMID: 35285800."
Proper citation: RRID:WB-STRAIN:WBStrain00055105 Copy
http://www.wormbase.org/db/get?name=WBStrain00055107
Source Database: WormBase (WB)
Affected Genes: WBGene00003760(nlp-22)
Genomic Alteration: WBGene00003760(nlp-22)
Availability: unknown
Source References: EMPTY
Synonyms: nlp-22(syb3319[nlp-22::T2A::3NLS::GFP]) X.
Notes: Endogenous locus tagged with T2A::3xNLS::GFP using CRISPR/Cas9. Please contact Oliver Hobert prior to publishing work using this strain.|"Made_by: Suny Biotech"
Proper citation: RRID:WB-STRAIN:WBStrain00055107 Copy
http://www.wormbase.org/db/get?name=WBStrain00055071
Source Database: WormBase (WB)
Affected Genes: WBGene00011997(nlp-51)
Genomic Alteration: WBGene00011997(nlp-51)
Availability: unknown
Source References: PMID:37935195
Synonyms: nlp-51(syb2805 [nlp-51::T2A::3xNLS::GFP]) II.
Notes: GFP tag inserted at the C-terminus of the endogenous nlp-51 locus by CRISPR. Allele generated by SUNY Biotech. Please contact Oliver Hobert prior to publishing work using this strain.|"GFP tag inserted at the C-terminus of the endogenous nlp-51 locus by CRISPR. Allele generated by SUNY Biotech. Reference: Taylor SR, et al. Cell. 2021 Aug 5;184(16):4329-4347.e23. doi: 10.1016/j.cell.2021.06.023. PMID: 34237253."|"Made_by: Suny Biotech"|"Supplementary_genotype nlp-51(syb2805 [nlp-51::T2A::3xNLS::GFP]) II"
Proper citation: RRID:WB-STRAIN:WBStrain00055071 Copy
http://www.wormbase.org/db/get?name=WBStrain00055070
Source Database: WormBase (WB)
Affected Genes: WBGene00003779(nob-1)
Genomic Alteration: WBGene00003779(nob-1)
Availability: unknown
Source References: PMID:38421866
Synonyms: nob-1(syb2679[nob-1::GFP]) III.
Notes: GFP tag inserted at the C-terminus of the endogenous nob-1 locus by CRISPR. Reference: Murray JI, et al. PLOS Genet. 2022 May 2;18(5):e1010187. PMID: 35500030|"Made_by: Xiulan Hu"
Proper citation: RRID:WB-STRAIN:WBStrain00055070 Copy
http://www.wormbase.org/db/get?name=WBStrain00055212
Source Database: WormBase (WB)
Affected Genes: WBGene00011621(T08G3.13)
Genomic Alteration: WBGene00011621(T08G3.13)
Availability: unknown
Source References: EMPTY
Synonyms: T08G3.13(sy2075) V.
Notes: Made_by: Heenam Park|"Superficially wild type. CRISPR/Cas9 engineered STOP-IN null mutant of T08G3.13. Universal 43bp-long knock-in insertion with 3-frame stop codon (STOP-IN cassette). Left flanking sequence: ctattttgattgaattATGTCTGTTATCGAGTTATGTGT. Right flanking sequence: CGGAGGACAGAAGTTCACAACGACGAAAACTAC. Inserted sequence between the two-flanking sequence (STOP-IN cassette): GGGAAGTTTGTCCAGAGCAGAGGTGACTAAGTGATAAgctagc. sgRNA: GTTATCGAGTTATGTGTCGG. Method Reference: Wang H, et al. G3 (Bethesda). 2018 Nov 6;8(11):3607-3616."
Proper citation: RRID:WB-STRAIN:WBStrain00055212 Copy
http://www.wormbase.org/db/get?name=WBStrain00055178
Source Database: WormBase (WB)
Affected Genes: WBGene00010306(golg-4)
Genomic Alteration: WBGene00010306(golg-4)
Availability: unknown
Source References: EMPTY
Synonyms: golg-4(syb6547[wrmScarlet::golg-4]) III.
Notes: Made_by: SUNY Biotech|"wrmScarlet tag inserted at the N-terminus of the endogenous golg-4 locus by CRISPR. Broad punctate wrmScarlet expression. Allele generated by SUNY Biotech. Please contact Oliver Hobert prior to publishing work using this strain."
Proper citation: RRID:WB-STRAIN:WBStrain00055178 Copy
http://www.wormbase.org/db/get?name=WBStrain00055175
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: F36D1.23(syb6466[F36D1.23::tagRFP]) I.
Notes: Made_by: SUNY Biotech|"tagRFP tag inserted at the C-terminus of the endogenous F36D1.23 locus by CRISPR. Strong and specific expression of GFP in excretory gland cell. Allele generated by SUNY Biotech. Please contact Oliver Hobert prior to publishing work using this strain."
Proper citation: RRID:WB-STRAIN:WBStrain00055175 Copy
http://www.wormbase.org/db/get?name=WBStrain00055176
Source Database: WormBase (WB)
Affected Genes: WBGene00006807(unc-75)
Genomic Alteration: WBGene00006807(unc-75)
Availability: unknown
Source References: EMPTY
Synonyms: unc-75(syb6499[gfp::unc-75]) I.
Notes: GFP tag inserted at the N-terminus of the endogenous unc-75 locus by CRISPR. Pan-neuronal nuclear expression of GFP. Allele generated by SUNY Biotech. Please contact Oliver Hobert prior to publishing work using this strain.|"Made_by: SUNY Biotech"
Proper citation: RRID:WB-STRAIN:WBStrain00055176 Copy
http://www.wormbase.org/db/get?name=WBStrain00055216
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: syIs483 X; syIs300.
Notes: syIs483 [unc-17p::NLS::cGAL(DBD)::gp41-1-N-intein::let-858 3'UTR + ceh-19p::NLS::gp41-1-C-intein::cGAL(AD)::let-858 3'UTR + unc-122p::RFP + 1kb DNA ladder (NEB)] X. Split cGAL driver for MC neuron. syIs300 [15xUAS::(delta)pes-10::GFP::let-858 3'UTR + ttx-3p::RFP + 1kb DNA ladder(NEB)] is a GFP cGAL effector. Some worms do not express ttx-3p::RFPmarker, but will consistently produce worms with the transgenic marker in next generation. Reference: Wang H, et al. Nat Methods. 2017 Feb;14(2):145-148.
Proper citation: RRID:WB-STRAIN:WBStrain00055216 Copy
http://www.wormbase.org/db/get?name=WBStrain00055215
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: syIs392.
Notes: syIs392 [unc-17p::NLS::GAL4(sk)::VP64::let-858 3'UTR + unc-122p::RFP + 1kb DNA ladder (NEB)] cGAL driver for Cholinergic neurons. Reference: Wang H, et al. Nat Methods. 2017 Feb;14(2):145-148.
Proper citation: RRID:WB-STRAIN:WBStrain00055215 Copy
http://www.wormbase.org/db/get?name=WBStrain00055218
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:38096407, PMID:39738055
Synonyms: syIs526 III.
Notes: syIs526 [flp-24p::NLS::GAL4(sk)::VP64::let-858 3'UTR + unc-122p::RFP + 1kb DNA ladder (NEB)]. cGAL driver for ALA neurons.
Proper citation: RRID:WB-STRAIN:WBStrain00055218 Copy
http://www.wormbase.org/db/get?name=WBStrain00055182
Source Database: WormBase (WB)
Affected Genes: WBGene00003767(nlp-29)
Genomic Alteration: WBGene00003767(nlp-29)
Availability: unknown
Source References: EMPTY
Synonyms: nlp-29(syb7352[nlp-29::SL2::GFP::H2B]) V.
Notes: Endogenous locus tagged with SL2::GFP::H2B using CRISPR/Cas9. Please contact Oliver Hobert prior to publishing work using this strain.|"Made_by: Suny Biotech"
Proper citation: RRID:WB-STRAIN:WBStrain00055182 Copy
http://www.wormbase.org/db/get?name=WBStrain00055183
Source Database: WormBase (WB)
Affected Genes: WBGene00003745(nlp-7)
Genomic Alteration: WBGene00003745(nlp-7)
Availability: unknown
Source References: EMPTY
Synonyms: nlp-7b(syb7377[nlp-7b::SL2::GFP::H2B]) X.
Notes: Endogenous nlp-7 locus (B-isoform) tagged with SL2::GFP::H2B using CRISPR/Cas9. Please contact Oliver Hobert prior to publishing work using this strain.|"Made_by: Suny Biotech"
Proper citation: RRID:WB-STRAIN:WBStrain00055183 Copy
http://www.wormbase.org/db/get?name=WBStrain00055180
Source Database: WormBase (WB)
Affected Genes: WBGene00006798(unc-64)
Genomic Alteration: WBGene00006798(unc-64)
Availability: unknown
Source References: EMPTY
Synonyms: unc-64(syb6739[unc-64::SL2::GFP::H2B) III.
Notes: GFP tag inserted at the C-terminus of the endogenous unc-64 locus by CRISPR. Ubiquitous expression of GFP. Allele generated by SUNY Biotech. Please contact Oliver Hobert prior to publishing work using this strain.|"Made_by: SUNY Biotech"
Proper citation: RRID:WB-STRAIN:WBStrain00055180 Copy
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