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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00029237
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: ltSi910 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:OD2768, CGC_OD2768
Notes: ltSi910 [elt-2p::vhhGFP4::zif-1::operon-linker::mCherry::his-11::tb b-2 3'UTR + Cbr-unc-119(+)] II. This transgenic strain mediates intestine-specific degradation of GFP-tagged proteins; can be combined with endogenous locus GFP-tagging or rescue of a null mutant with a GFP fusion to examine intestine-specific functions of target genes. Reference: Wang S, et al. URL: biorxiv.org/content/early/2017/01/30/104398|"ltSi910 [elt-2p::vhhGFP4::zif-1::operon-linker::mCherry::his-11::tbb-2 3'UTR + Cbr-unc-119(+)] II. This transgenic strain mediates intestine-specific degradation of GFP-tagged proteins; can be combined with endogenous locus GFP-tagging or rescue of a null mutant with a GFP fusion to examine intestine-specific functions of target genes.Reference: Wang S, et al. Development. 2017 Jun 15. pii: dev.150094. doi: 10.1242/dev.150094."
Proper citation: RRID:WB-STRAIN:WBStrain00029237 Copy
http://www.wormbase.org/db/get?name=WBStrain00029233
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:38743783
Synonyms: ltSi240 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:OD923, CGC_OD923
Notes: ltSi240 [csr-1p::csr-1(re-encoded) + Cbr-unc-119(+)] II. The csr-1 coding sequence in the transgene was re-encoded for RNAi-resistance (see Gerson-Gurwitz A, et al. Cell. 2016, Supplementary Figure S3A). Reference: Gerson-Gurwitz, et al. Cell. 2016 Apr 7;165(2):396-409.
Proper citation: RRID:WB-STRAIN:WBStrain00029233 Copy
http://www.wormbase.org/db/get?name=WBStrain00029234
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:38743783
Synonyms: ltSi242 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:OD925, CGC_OD925
Notes: ltSi242 [csr-1p::csr-1(re-encoded; D606A, D681A: isoform b numbering) + Cbr-unc-119(+)] II. The csr-1 coding sequence in the transgene was re-encoded for RNAi-resistance (see Gerson-Gurwitz A, et al. Cell. 2016, Supplementary Figure S3A). Reference: Gerson-Gurwitz, et al. Cell. 2016 Apr 7;165(2):396-409.
Proper citation: RRID:WB-STRAIN:WBStrain00029234 Copy
http://www.wormbase.org/db/get?name=WBStrain00029230
Source Database: WormBase (WB)
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; ltIs105.
Alternate IDs: WB-STRAIN:OD178, CGC_OD178
Notes: ltIs105 [(pAA280) pie-1p::GFP::LAP::MVB-12 + unc-119(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00029230 Copy
http://www.wormbase.org/db/get?name=WBStrain00029231
Source Database: WormBase (WB)
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119)
Availability: available
Source References: PMID:36652947
Synonyms: unc-119(ed3) III; ltIs79; pwIs116.
Alternate IDs: WB-STRAIN:OD179, CGC_OD179
Notes: ltIs79 [(pAA196) pie-1p::mCherry::rab-5 + unc-119(+)]. pwIs116 [rme-2p::rme-2::GFP::rme-2 3'UTR + unc-119(+)]. Maintain at 20-25C to reduce silencing of the array.
Proper citation: RRID:WB-STRAIN:WBStrain00029231 Copy
http://www.wormbase.org/db/get?name=WBStrain00029229
Source Database: WormBase (WB)
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; ltIs104.
Alternate IDs: WB-STRAIN:OD177, CGC_OD177
Notes: ltIs104 [(pAA277) pie-1p::GFP::LAP::vps-37 + unc-119(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00029229 Copy
http://www.wormbase.org/db/get?name=WBStrain00029225
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; ltIs78.
Alternate IDs: WB-STRAIN:OD142, CGC_OD142
Notes: ltIs78 [(pKO5) pie-1::GFP::TEV::Stag::air-1 spliced coding + unc-119(+)].|"Made_by: Oegema/Portier"
Proper citation: RRID:WB-STRAIN:WBStrain00029225 Copy
http://www.wormbase.org/db/get?name=WBStrain00029228
Source Database: WormBase (WB)
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; ltIs103.
Alternate IDs: WB-STRAIN:OD176, CGC_OD176
Notes: ltIs103 [(pAA212) pie-1p::GFPLAP::cav-1 + unc-119(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00029228 Copy
http://www.wormbase.org/db/get?name=WBStrain00029260
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: drSi4 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:OG474, CGC_OG474
Notes: drSi4 [vha-6p::3XFLAG::pgp-3/CFTR(delta F508)::mCherry::unc-54 3'UTR] II. Superficially wild-type with mCherry expression only in the intestine with significantly diminished expression as compared to drSi2. Single copy integration of the vha-6 promoter driving the PGP-3 protein with an N-terminal 3XFLAG tag and a C-terminal mCherry tag. Amino acids 476-484 of PGP-3 have been replaced with amino acids 501-509 of human CFTR with F508 deleted (TIKENII_G). Transgene was inserted at the ttTi5605 locus on LGII and verified to be a single copy insertion by long range PCR across the genomic locus. Reference: He L, et al. Dis Model Mech. 2012 Nov;5(6):930-9.
Proper citation: RRID:WB-STRAIN:WBStrain00029260 Copy
http://www.wormbase.org/db/get?name=WBStrain00029257
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; drEx206.
Alternate IDs: WB-STRAIN:OG153, CGC_OG153
Notes: drEx206 [hsf-1p::hsf-1::YFP::unc-54 3'UTR + unc-119(+)]. Reference: Morton EA, Lamitina T. Aging Cell. 2012 Oct 26. doi: 10.1111/acel.12024.
Proper citation: RRID:WB-STRAIN:WBStrain00029257 Copy
http://www.wormbase.org/db/get?name=WBStrain00029588
Source Database: WormBase (WB)
Affected Genes: WBGene00004949(sox-2)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004949(sox-2), WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; sox-2(ot640[unc-119(+)]) X; otEx4454.
Alternate IDs: WB-STRAIN:OH10053, CGC_OH10053
Notes: otEx4454 [sox-2(fosmid)::mCherry + elt-2p::DsRed]. ot640 was generated by using MosDel removing the entire sox-2 locus and insert unc-119(+). ot640 homozygous arrest in L1 with a pharynx unattached (Pun) phenotype. Maintain by picking WT DsRed+ to maintain. Reference: Vidal B, et al. Development. 2015 Jul 15;142(14):2464-77.|"otEx4454 [sox-2(fosmid)::mCherry + elt-2p::DsRed]. ot640 was generated by using MosDel removing the entire sox-2 locus and insert unc-119(+). ot640 homozygous arrest in L1 with a pharynx unattached (Pun) phenotype. Maintain by picking WT to maintain (transgene should be required for viability). Reference: Vidal B, et al. Development. 2015 Jul 15;142(14):2464-77."
Proper citation: RRID:WB-STRAIN:WBStrain00029588 Copy
http://www.wormbase.org/db/get?name=WBStrain00029956
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wgIs18.
Alternate IDs: WB-STRAIN:OP18, CGC_OP18
Notes: Generated from Paper data WBPaper00060123|"Made_by: modEncode"|"Modern strain"|"wgIs18 [lin-39::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of lin-39 coding sequence of fosmid ID#WRM0616aE11 by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029956 Copy
http://www.wormbase.org/db/get?name=WBStrain00029958
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wgIs27.
Alternate IDs: WB-STRAIN:OP27, CGC_OP27
Notes: Generated from Paper data WBPaper00060123|"Made_by: modEncode"|"Modern strain"|"wgIs27 [mab-5::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of mab-5 coding sequence of fosmid ID#WRM0640bH09 by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029958 Copy
http://www.wormbase.org/db/get?name=WBStrain00029979
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wgIs62.
Alternate IDs: WB-STRAIN:OP62, CGC_OP62
Notes: Made_by: modEncode|"Modern strain"|"wgIs62 [lin-11::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029979 Copy
http://www.wormbase.org/db/get?name=WBStrain00029976
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:32628333
Synonyms: unc-119(ed3) III; gaEx290.
Alternate IDs: WB-STRAIN:OP56, CGC_OP56
Notes: gaEx290 [elt-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. Pick non-Unc to maintain. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Recombineered fosmid was integrated by biolistic bombardment. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Mann F, et al. PLoS. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)|"gaEx290 [elt-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Recombineered fosmid was integrated by biolistic bombardment. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Mann F, et al. PLoS. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"|"gaIs290 [elt-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Recombineered fosmid was integrated by biolistic bombardment. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Mann F, et al. PLoS. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"|"Made_by: modENCODE"|"Modern strain"|"WBStrain mapped, WBPaper00059970 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00029976 Copy
http://www.wormbase.org/db/get?name=WBStrain00029968
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37643611
Synonyms: unc-119(ed3) III; wgIs43.
Alternate IDs: WB-STRAIN:OP43, CGC_OP43
Notes: Made_by: modEncode|"Modern strain"|"Supplementary_genotype unc-119(ed3) III; wgIs43[nhr-23::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]"|"wgIs43 [nhr-23::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Gerstein MB, et al. Science. 2010 Dec 24;330(6012):1775-87. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029968 Copy
http://www.wormbase.org/db/get?name=WBStrain00029964
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wgIs34.
Alternate IDs: WB-STRAIN:OP34, CGC_OP34
Notes: Made_by: modEncode|"wgIs34 [ama-1::TY1::EGFP::3xFLAG + unc-119(+)]. Slightly Dpy. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of ama-1 coding sequence of fosmid ID#WRM0610dA01 by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029964 Copy
http://www.wormbase.org/db/get?name=WBStrain00029999
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wgIs92.
Alternate IDs: WB-STRAIN:OP92, CGC_OP92
Notes: Made_by: EAP/DKV/JIM|"Modern strain"|"wgIs92 [sdc-2::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00029999 Copy
http://www.wormbase.org/db/get?name=WBStrain00029995
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wgIs86.
Alternate IDs: WB-STRAIN:OP86, CGC_OP86
Notes: Made_by: modEncode|"Modern strain"|"wgIs86 [peb-1::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Gerstein MB, et al. Science. 2010 Dec 24;330(6012):1775-87. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029995 Copy
http://www.wormbase.org/db/get?name=WBStrain00029997
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; wgIs90.
Alternate IDs: WB-STRAIN:OP90, CGC_OP90
Notes: Made_by: modEncode|"Modern strain"|"wgIs90 [nhr-6::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029997 Copy
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