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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60995
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 60995
Notes: Recombinant inbred strain used as normotensive control in studies of hypertension.
Proper citation: RRID:RGD_60995 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60996
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 60996
Notes: R. Sato 1950 by inbreeding Japanese albino rats.
Proper citation: RRID:RGD_60996 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60997
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 60997
Notes: Developed from stock of unstated origin by Dr. T.T. Odell, Jr. at Oak Ridge National Laboratory, Tennessee to F11, then by Dr. Darcy Wilson at the Wistar Institute, who named it DA because it expressed the 'd' blood group allele of Joy Palm, and it is 'a' agouti in colour (Wilson 1965). Inbreeding was completed in about 1965. Although Palm and Black (1971) suggest it may be related to COP, there is no real evidence that this is the case.
Proper citation: RRID:RGD_60997 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60998
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 60998
Notes: This Copenhagen (COP) rat was an inbred strain from Curtiss 1921 at Columbia University Institute for Cancer Research.
Proper citation: RRID:RGD_60998 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10043120
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 10043120
Notes: 104 Mb region from ACI.BBDP-(RT1u),(Gimap5)/Sunn is introgressed into the BBDP/WorSunn background which includes Iddm26, Iddm33 QTL regions and a small fragment of Iddm32
Proper citation: RRID:RGD_10043120 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60999
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 60999
Notes: Dr. Margaret Lewis from Wistar stock, to Aptekman and Bogden 1954 at F20, to Silvers in 1958 at F31. Subsequently distributed by Silvers. Used as the inbred partner for a number of congenic strains at the major histocompatibility complex (Stark and Kren 1969). A substrain with congenital hydrocephalus due to primary aqueductal stenosis has been described by Yamada et al, (1992) Harlan Sprague Dawley Inc. Indianapolis, United States
Proper citation: RRID:RGD_60999 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10045545
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10045545
Notes: Original breeders are from a colony at Hadassah University Hospital, Jerusalem, Israel: Professor Cohen AM et al. initiated the Cohen diabetic (CD) rat model at the Hadassah University Hospital in the 1950s to examine the role of constitutional (genetic) and environmental (dietary) factors in the development of type 2 diabetes mellitus. Since 1996, the original colony underwent a secondary inbreeding by Dr. Sarah Zangen designated by Prof. Cohen as responsible for the Cohen diabetic (CD) rat colony.
Proper citation: RRID:RGD_10045545 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10043124
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 10043124
Notes: 104 Mb region from ACI.BBDP-(RT1u),(Gimap5)/Sunn is introgressed into the BBDP/WorSunn background which carries the centromeric region of Iddm26 and a small fragment of Iddm32
Proper citation: RRID:RGD_10043124 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=628909
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 628909
Notes: Segment of chromosome 13 from the normotensive BN/Crl was transferred to SHR. After 10 generations of backcrossing to SHR, the differential segment was fixed with the flanking markers.These were maintained in the homozygous state by brother x sister mating. The size of the chromosome transferred is 2.5 cM with an additional 16 cM region of heterozygosity.
Proper citation: RRID:RGD_628909 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=628908
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 628908
Notes: Segment of chromosome 1 from the normotensive BN/Cr was transferred to SHR. After 10 generations of backcrossing to SHR, the differential segment was fixed with the flanking markers.These were maintained in the homozygous state by brother x sister mating.
Proper citation: RRID:RGD_628908 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67971
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 67971
Notes: Strain developed by crossing BB/Wor rats, a lean model of type I diabetes mellitus with a Zucker fatty (fa ) rat of unstated genetic background, followed by sib mating with forced heterozygosity for the fatty gene. Thus in each generation there is a ratio of 3
Proper citation: RRID:RGD_67971 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=734528
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 734528
Notes: Female OLETF/Got rats were crossed with male BN rats. The F1 were backcrossed to OLETF to produce the BC1. Selective males from BC1 were backcrossed to OLETF to produce successive congenic generations.
Proper citation: RRID:RGD_734528 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67975
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 67975
Notes: Druckrey 1937 from a yellow, pink-eyed strain. Inbred and reduced to one pair after World War II. Crosses with Wistar stock and subsequent inbreeding led to the development of BDII. According to Druckrey (1971), strains BDIII-BDX were then developed from a cross of a single BDI x BDII mating pair, with subsequent selection for coat colour alleles. However, the strains have four different RT1 haplotypes (d, v, l and e) rather than the two that would be expected from such a cross (Stark and Zeiss 1970). The strains can _not_ be regarded as a set of recombinant inbred strains as defined by Bailey (1971), although their definition by coat colour alleles makes the set easily identifiable , and should help (but not guarantee!) to ensure authenticity. According to Druckrey (1971), all strains have a low tumour incidence, with a median life-span of 700-950 days, depending on strain.
Proper citation: RRID:RGD_67975 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67974
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 67974
Notes: Zentralinstitut fur Versuchstierzucht, Hannover, from a cross between BDVII and E3, with selection for black hooded offspring.
Proper citation: RRID:RGD_67974 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=152999023
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 152999023
Notes: Applied StemCell, Inc (Milpitas, CA) was contracted to generate the Iba1-EGFP knock-in rat model using
CRISPR/Cas9 technology in the Sprague Dawley rat strain. The donor construct inserted consisted of the
EGFP coding sequence (minus the first ATG), followed by the 22 amino acid sequence of the porcine
teschovirus-1 2A (P2A) self-cleaving peptide, and then the first exon of the rat Iba1 gene immediately
downstream of the translational start site. Guide RNA with the following sequence: 5'- TACCCTGCAAATCCTTGCTCTGG-3' targeting the Iba1 gene just
downstream of the translational start site were used.
Proper citation: RRID:RGD_152999023 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10033
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10033
Proper citation: RRID:RGD_10033 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10037
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10037
Notes: From Sprague-Dawley stock of an unknown source to Hoechst, Frankfurt. To O. Haferkamp, University of Ulm, to ITRI-TNO Rijswijk, The Netherlands in 1972 (van Hooft 1990). Note that other sublines of "SD" rats (including SD/A, SD/Cpb, and SD/Waa) are known to differ among themselves, and from this strain (Bender et al 1984, Festing and Bender 1984). Harlan Rijswijk
Proper citation: RRID:RGD_10037 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10038
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10038
Notes: Harlan Sprague Dawley, Inc.
Proper citation: RRID:RGD_10038 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10035
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10035
Proper citation: RRID:RGD_10035 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67960
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 67960
Notes: Derived from one of the US August sublines in 1951 and distributed by the Chester Beatty Institute, Pollards Wood, England.
Proper citation: RRID:RGD_67960 Copy
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