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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
RNA FRABASE - RNA FRAgments search engine and dataBASE
 
Resource Report
Resource Website
RNA FRABASE - RNA FRAgments search engine and dataBASE (RRID:SCR_012808) RNA FRABASE data analysis service, data or information resource, database, service resource, d spatial image, production service resource, analysis service resource Engine and database to search the three-dimensional fragments within 3D RNA structures using as an input the sequence(s) and / or secondary structure(s) given in the dot-bracket notation. The database contains RNA sequences and secondary structures, described in the dot-bracket notation, derived from PDB-deposited RNA structures and their complexes. It also contains atom coordinates of the unmodified and modified nucleotide and nucleoside residues extracted from the PDB-deposited RNA structures, as well as torsion and pseudotorsion angle values, sugar pucker parameters and classification of base pair types given for the PBD-deposited RNA structures. Knowledge of the three dimensional RNA structure is crucial for all fields of biomolecular research. In contrast to the protein field, only about 1.300 experimentally derived structures of RNAs are deposited in the Protein Data Bank (PDB). To complement the results of experimental studies, new approaches based on bioinformatics and calculation are pursued in several laboratories to make tertiary RNA structure prediction possible. RNA FRABASE version 2.0 should greatly facilitate various RNA structure modelling approaches, RNA structure analysis and motif searching. If one compares the three dimensional RNA structure to a spatial puzzle, the RNA FRABASE allows to pull out a defined piece of this puzzle - the 3D RNA fragment. The architecture of the web-accessible RNA FRABASE engine and database is based on the following information path: PDB-deposited RNA structures �� RNA sequences and secondary structures described in the dot-bracket notation �� secondary structures of RNA fragments �� 3D RNA fragments. RNA FRABASE 2.0 also stores data and conformational parameters in order to provide on the spot structural filters to explore the three-dimensional RNA structures. An instant visualization of the 3D RNA structures is provided. structural element, secondary structure, rna, rna structure, 3d rna fragment, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Polish Academy of Sciences Poznan; Poznan; Poland
Foundation for Polish Science SP 01/04;
Ministry of Education and Science 3T09A014 29;
Polish Ministry of Science and Higher Education PBZ-MniSW-07/1/2007/01;
Polish Ministry of Science and Higher Education NN 519314635
PMID:20459631
PMID:17921499
nif-0000-03413, biotools:rna_frabase https://bio.tools/rna_frabase SCR_012808 RNA FRAgments search engine dataBASE, RNA FRAgments search engine and dataBASE, RNA FRABASE - RNA FRAgments search engine dataBASE 2026-07-31 09:27:09 0
GeMoMa
 
Resource Report
Resource Website
100+ mentions
GeMoMa (RRID:SCR_017646) software resource, software application, simulation software Software tool as homology based gene prediction program that predicts gene models in target species based on gene models in evolutionary related reference species. Utilizes amino acid sequence conservation, intron position conservation, and RNA-seq data to accurately predict protein-coding transcripts. Supports combination of predictions based on several reference species allowing to transfer high quality annotation of different reference species to target species. Homology, based, gene, prediction, model, target, evolutionary, related, reference, species, sequence, conservation, intron, position, RNAseq, data, protein, coding, transcript, bio.tools is listed by: bio.tools
is listed by: Debian
works with: GUSHR
PMID:31020559 Free, Available for download, Freely available biotools:gemoma https://bio.tools/gemoma SCR_017646 Gene Model Mapper 2026-07-31 09:28:11 135
Roary
 
Resource Report
Resource Website
500+ mentions
Roary (RRID:SCR_018172) data analysis software, software application, software resource, sequence analysis software, data processing software Software tool for rapid large scale prokaryote pan genome analysis. Builds large scale pan genomes, identifying core and accessory genes. Makes construction of pan genome of thousands of prokaryote samples on standard desktop without compromising on accuracy of results. Not intended for meta genomics or for comparing extremely diverse sets of genomes. Genome analysis, prokaryote pan genome, pan genome, gene identification, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
works with: Scoary
Wellcome Trust PMID:26198102 Free, Available for download, Freely available OMICS_09491, biotools:roary https://github.com/sanger-pathogens/Roary, https://bio.tools/roary, https://sources.debian.org/src/roary/ SCR_018172 2026-07-31 09:28:13 602
R/qtl2
 
Resource Report
Resource Website
10+ mentions
R/qtl2 (RRID:SCR_018181) data processing software, data analysis software, software application, software resource Software R package for mapping quantitative trait loci with high dimensional data and multiparent populations. Used for analysis of high dimensional data and complex crosses. Interactive software environment for mapping quantitative trait loci in experimental populations.R/qtl2 software expands scope of R/qtl software package to include multiparent populations derived from more than two founder strains, such as Collaborative Cross and Diversity Outbred mice, heterogeneous stocks, and MAGIC plant populations. High density genotyping data, molecular phenotype, gene expression, proteomics, mapping trait loci, diversity outbred mice, bio.tools is listed by: Debian
is listed by: bio.tools
NIGMS R01 GM074244;
NIGMS R01 GM070683;
NIGMS R01 GM123489
PMID:30591514 Free, Available for download, Freely available biotools:R_qtl2, SCR_020965 https://bio.tools/R_qtl2, https://kbroman.org/qtl2, https://github.com/rqtl/qtl2 SCR_018181 QTL, R/quantitative trait loci, QTL2, Quantitative Trait Locus 2, quantitative trait loci 2, R/qtl, qtl2 2026-07-31 09:28:27 13
Berkeley Advanced Reconstruction Toolbox
 
Resource Report
Resource Website
1+ mentions
Berkeley Advanced Reconstruction Toolbox (RRID:SCR_016168) BART image analysis software, image reconstruction software, software application, software resource, data processing software Image reconstruction software for MRI. Its library provides common operations on multi-dimensional arrays, Fourier and wavelet transforms, as well as generic implementations of iterative optimization algorithms. mri, reconstruction, magnetic, resonance, neuroimaging, array, transform, algorithm is listed by: Debian NCRR R41 RR09784;
American Heart Association 12BGIA9660006;
NIBIB R01 EB009690;
UC Discovery 193037;
Sloan Research Fellowship ;
GE Healthcare
Open source, Free https://mrirecon.github.io/bart/, https://sources.debian.org/src/bart/ SCR_016168 2026-07-31 09:27:52 7
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) data analysis software, software application, software resource, sequence analysis software, data processing software Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
the Cancer Prevention and Research Institute of Texas ;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
NHGRI R01 HG006102;
NCI R01 CA120185;
NCI R01 CA134292
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie, https://bio.tools/stringtie, https://sources.debian.org/src/stringtie/ SCR_016323 2026-07-31 09:27:57 4072
CMap
 
Resource Report
Resource Website
100+ mentions
CMap (RRID:SCR_016204) data or information resource, database, web application, data set, software resource Dataset of cellular signatures that catalogs transcriptional responses of human cells to chemical and genetic perturbation. CMap contains perturbagens, expression signatures, and small molecules from cell lines. data, set, connectivity, gene, expression, database, heat map, drug, tool, perturbational, perturbagen, signature, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: Broad Institute
Free for academic use, Subscription for commercial use, Available for download, Acknowledgement requested biotools:CMap https://bio.tools/CMap SCR_016204 LINCS CMap L1000, LINCS L1000, LINCS CMap, ConnectivityMap, Connectivity Map 2026-07-31 09:27:53 483
Hinge
 
Resource Report
Resource Website
1+ mentions
Hinge (RRID:SCR_016135) data analysis software, software application, software resource, sequence analysis software, data processing software Software application for long read genome assembly based on hinging. Used in long-read sequencing technologies in genome assemblies to achieve optimal repeat resolution. long, read, genome, assembly, hinging, sequence, optimal, repeat, resolution is listed by: Debian
is listed by: OMICtools
PMID:28320918 Free, Available for download OMICS_12339 https://sources.debian.org/src/hinge/ SCR_016135 2026-07-31 09:27:55 9
HH-suite
 
Resource Report
Resource Website
10+ mentions
HH-suite (RRID:SCR_016133) software toolkit, data analysis software, software application, software resource, sequence analysis software, data processing software Software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). Used for sequence-based protein function and structure prediction what depends on sequence-search sensitivity and accuracy of the resulting sequence alignments. protein, sensitive sequence search, pairwise alignment, multiple database, homologous structure, prediction, modeling, bio.tools is listed by: Debian
is listed by: bio.tools
the Deutsche Forschungsgemeinschaft grant SFB646;
Ludwig-Maximilians Universität Munich ;
Excellence Initiative of the Bundesministerium für Bildung und Forschung
DOI:10.1186/s12859-019-3019-7 Free, Available for download, Freely available biotools:hh-suite https://bio.tools/hh-suite http://toolkit.genzentrum.lmu.de/sections/search SCR_016133 2026-07-31 09:27:56 49
SMARTdenovo
 
Resource Report
Resource Website
100+ mentions
SMARTdenovo (RRID:SCR_017622) image analysis software, alignment software, software application, software resource, data processing software Software tool as de novo assembler for PacBio and Oxford Nanopore data. It produces assembly from all-vs-all raw read alignments without error correction stage. Allows to read overlapping, rescue missing overlaps, identify low-quality regions and chimaera and produce better consensus. De novo, assembler, PacBio, Oxford Nanopore, data, sequence, raw, read, alignment, error, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available BioTools:SMARTdenovo, biotools:SMARtdenovo https://bio.tools/SMARTdenovo, https://bio.tools/SMARTdenovo, https://bio.tools/SMARTdenovo SCR_017622 2026-07-31 09:28:22 159
pheatmap
 
Resource Report
Resource Website
1000+ mentions
pheatmap (RRID:SCR_016418) pheatmap software toolkit, data acquisition software, software application, software resource, data processing software, image acquisition software Software tool as a function in R to draw clustered heatmaps for better control over graphical parameters. draw, clustered, heatmap, control, graphical, parameter, size, shape, text, bio.tools is used by: ClustVis
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
is related to: CRAN
Free, Available for download, Freely available biotools:pheatmap, OMICS_26726 https://github.com/raivokolde/pheatmap, https://cran.r-project.org/web/packages/pheatmap/pheatmap.pdf, https://bio.tools/pheatmap, https://sources.debian.org/src/r-cran-pheatmap/ SCR_016418 pretty heatmap 2026-07-31 09:27:57 1068
FreeContact
 
Resource Report
Resource Website
10+ mentions
FreeContact (RRID:SCR_016113) image analysis software, alignment software, software application, software resource, data processing software Alignment software for large-scale protein contact or protein-protein interaction prediction optimized for speed through shorter runtimes. FreeContact provides the opportunity to compute contact predictions in any environment (desktop or cloud). protein, structure, prediction, sequence, analysis, fast, contact, alignment, multiple is listed by: OMICtools
is related to: Debian
Alexander von Humboldt Foundation ;
German Ministry for Research and Education (BMBF: Bundesministerium fuer Bildung und Forschung) ;
Research Council of Norway 208481
PMID:24669753
DOI:10.1186/1471-2105-15-85
Open source, Free, Available for download OMICS_03520 https://rostlab.org/owiki/index.php/FreeContact, https://sources.debian.org/src/libfreecontact-perl/ SCR_016113 2026-07-31 09:27:56 21
JAMM
 
Resource Report
Resource Website
1+ mentions
JAMM (RRID:SCR_017049) data processing software, data analysis software, software application, software resource Software tool as peak finder for joint analysis of NGS replicates. Used for peak finding in next generation sequencing broad and narrow datasets like ChIP-Seq, ATAC-Seq, DNase-Seq. Can integrate information from biological replicates and assign peak boundaries accurately. peak, finder, sequencing, dataset, integrate, replicate, boundary, accurately, bio.tools is listed by: Debian
is listed by: bio.tools
Max-Delbrück-Center/New York University Exchange Program. PMID:25223640 Free, Available for download, Freely available biotools:jamm https://bio.tools/jamm SCR_017049 J oint A nalysis of NGS replicates via M ixture M odel clustering, Joint Analysis of NGS replicates via Mixture Model clustering 2026-07-31 09:28:04 2
NetPhos
 
Resource Report
Resource Website
100+ mentions
NetPhos (RRID:SCR_017975) data access protocol, service resource, software application, production service resource, software resource, standalone software, web service, analysis service resource Web tool as artificial neural network method that predicts phosphorylation sites in independent sequences. Web application based on determination of activity of protein kinases using in vitro assays with either naturally occurring peptides or synthetic peptides. NetPhos 3.1 server predicts serine, threonine or tyrosine phosphorylation sites in eukaryotic proteins using ensembles of neural networks. Both generic and kinase specific predictions are performed. Generic predictions are identical to predictions performed by NetPhos 2.0. Kinase specific predictions are identical to predictions by NetPhosK 1.0. NetPhos 3.1 is available as stand-alone software package. Neural network, predict, phosphorylation site, independent sequence, protein, kinase, serine, threonine, tyrosine, eukaryotic, bio.tools is used by: YinOYang
is listed by: Debian
is listed by: bio.tools
has parent organization: Technical University of Denmark; Lyngby; Denmark
PMID:10600390 Free, Freely available biotools:netphos https://bio.tools/netphos http://www.cbs.dtu.dk/services/NetPhos-2.0/ SCR_017975 NetPhos 3.1, NetPhos 2.0 2026-07-31 09:28:23 381
NanoPipe
 
Resource Report
Resource Website
1+ mentions
NanoPipe (RRID:SCR_016852) NanoPipe data analysis service, data access protocol, service resource, production service resource, software resource, analysis service resource, web service Web tool for analysis of MinION (ONT) long sequencing reads. Used for analysis of reads generated by the Oxford Nanopore sequencing devices. Provides alignments to any target of interest, alignment statistics and information about polymorphisms. analysis, MinION, long, sequence, read, Oxford Nanopore, alignment, target, statistics, polymorphism, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Muenster; Muenster; Germany
Institute of Bioinformatics Muenster ;
Germany
PMID:30689855 Free, Available for download, Freely Available biotools:NanoPipe https://github.com/IOB-Muenster/nanopipe2, https://bio.tools/NanoPipe SCR_016852 NanoPipe, nanopipe2 2026-07-31 09:28:04 5
DETONATE
 
Resource Report
Resource Website
1+ mentions
DETONATE (RRID:SCR_017035) DETONATE data analysis software, software application, software resource, sequence analysis software, data processing software Software tool to evaluate de novo transcriptome assemblies from RNA-Seq data. Consists of RSEM-EVAL and REF-EVAL packages. RSEM-EVAL is reference-free evaluation method. REF-EVAL is reference based and can be used to compare sets of any kinds of genomic sequences. evaluate, de novo, transcriptome, assembly, RNAseq, data, RSEM-EVAL, REF-EVAL, dataset, genomic, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
NHGRI R01 HG005232;
NLM T15 LM007359
PMID:25608678 Free, Available for download, Freely available biotools:detonate https://bio.tools/detonate SCR_017035 DE novo TranscriptOme rNa-seq Assembly with or without the Truth Evaluation, DETONATE 2026-07-31 09:28:08 2
ClonalOrigin
 
Resource Report
Resource Website
1+ mentions
ClonalOrigin (RRID:SCR_016061) data analysis software, software application, software resource, sequence analysis software, data processing software Software package for comparative analysis of the sequences of a sample of bacterial genomes in order to reconstruct the recombination events that have taken place in their ancestry. comparative, analysis, sequence, bacteria, genome, reconstruct, recombination, events, ancestry, bayesian is listed by: Debian
is listed by: OMICtools
is related to: Imperial College London; London; United Kingdom
is related to: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust WT082930MA;
National Science Foundation DBI-0630765;
Science Foundation of Ireland 05/FE1/B882
PMID:20923983
DOI:10.1534/genetics.110.120121
Free, Available for download OMICS_18881 https://sources.debian.org/src/clonalorigin/ SCR_016061 2026-07-31 09:27:55 8
REDIportal
 
Resource Report
Resource Website
10+ mentions
REDIportal (RRID:SCR_018490) data or information resource, portal, database, service resource, topical portal, atlas Comprehensive database of A-to-I RNA Editing Events. Atlas of A-to-I RNA editing events in human and other organisms. Collection of A-to-I events in body sites of healthy individuals from GTEx project. RNA Editing sites can be searched by genomic region, gene name and other relevant features as tissue of origin. Query results are shown in sortable and downloadable tables in which main characteristics of individual RNA editing events are reported. RNA-Seq and DNA-Seq coverage per site as well as RNA editing levels are provided. A-to-I RNA Editing Events, RNA editing events collection, atlas, database, GTEx project, genomic region, gene name, RNAseq, DNAseq, , bio.tools is listed by: Debian
is listed by: bio.tools
is related to: CLAIRE
is related to: SIGNOR
Italian Ministero dell Istruzione ;
Consiglio Nazionale delle Ricerche
PMID:27587585 Free, Freely available biotools:rediportal https://bio.tools/rediportal SCR_018490 2026-07-31 09:28:16 30
MB-GAN
 
Resource Report
Resource Website
1+ mentions
MB-GAN (RRID:SCR_019289) software resource, software application, simulation software Software tool as deep learning simulation framework for simulating realistic microbiome data. Can automatically learn from given microbial abundances and compute simulated abundances that are indistinguishable from it. Metagenomics, deep learning, generative adversarial network, microbiome data simulation, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Texas at Dallas; Texas; USA
DOI:10.1101/863977 Free, Available for download, Freely available biotools:mb-gan https://bio.tools/mb-gan SCR_019289 Microbiome Simulation via Generative Adversarial Network 2026-07-31 09:28:49 1
SOAPnuke
 
Resource Report
Resource Website
1000+ mentions
SOAPnuke (RRID:SCR_015025) data analysis software, software application, software resource, sequence analysis software, data processing software Multi-threaded software for rapid quality control and preprocessing of high throughput sequencing data specified for different experiments. It consists of four modules that speed up the report on statistics graphs of raw datasets, preprocessed datasets and preprocessing status. sequence data, fastq, dge dataset, rna, metagenomics, bio.tools is listed by: SOAP
is listed by: bio.tools
is listed by: Debian
Open Source, Free biotools:soapnuke https://bio.tools/soapnuke SCR_015025 2026-07-31 09:27:43 1447

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