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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Provides genomics and molecular biology services for University of Delaware research groups and outside users.Supports genomic research through established expertise with genomics technologies.
Proper citation: University of Delaware Sequencing and Genotyping Center Core Facility (RRID:SCR_012230) Copy
http://www.scienceexchange.com/facilities/genomics-core-facility-brown
Provides genomics and proteomics equipment to researchers at Brown University and to entire Rhode Island research community, as well as assistance with experimental design, trouble shooting, and data analysis. Offers Affymetrix microarray and Illumina NextGeneration services to academic community and external customers.
Proper citation: Brown University Genomics Core Facility (RRID:SCR_012217) Copy
https://github.com/compbiolabucf/PTNet
Graph based learning model for protein expression estimation by considering miRNA-mRNA interactions. Estimates protein levels by considering miRNA-mRNA interaction network, mRNA expression and miRNA expression.
Proper citation: PTNet (RRID:SCR_022975) Copy
https://github.com/caraweisman/abSENSE
Software to interpret undetected homolog.Method that calculates probability that homolog of given gene would fail to be detected by homology search in given species, even if homolog were present and evolving normally.
Proper citation: abSENSE (RRID:SCR_023223) Copy
https://github.com/DeNardoLab/BehaviorDEPOT
Software tool for automated behavioral detection based on markerless pose tracking. Behavioral analysis tool to first compile and clean point-tracking output from DeepLabCut, and then classify behavioral epochs using custom behavior classifiers. Used to detect frame by frame behavior from video time series and can analyze results of common experimental assays, including fear conditioning, decision-making in T-maze, open field, elevated plus maze, and novel object exploration. Calculates kinematic and postural statistics from keypoint tracking data from pose estimation software outputs.
Proper citation: BehaviorDEPOT (RRID:SCR_023602) Copy
http://www.scienceexchange.com/facilities/nnin-nano-research-facility-wustl
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Nano Research Facility (NRF) at Washington University in St. Louis is a NNIN nodal facility supported by the National Science Foundation. It cultivates an open, shared research, and education environment that brings researchers across disciplines together, particularly in the emerging area of nanomaterials with applications in the energy, environment, and biomedical fields. The mission is to be a resource to the scientific and technical community for the advancement of nanoscience and nanotechnology in a safe and environmentally benign manner. NRF includes a micro- and nano-fabrication lab (clean room), surface characterization lab, particle technology lab, and imaging lab with a focus on bio-imaging. NRF provides unique technical expertise in: Knowledge-based synthesis of nanostructured materials Particle instrumentation tools for toxicity studies Non-invasive imaging modalities for biological applications Clean Energy Applications Energy and Environmental nanotechology Environmental Health and Safety As a member of the National Nanotechnology Infrastructure Network (NNIN), supported by the National Science Foundation, NRF is available to both academic and industrial users nation-wide and across the globe.
Proper citation: WUSTL NNIN - Nano Research Facility (RRID:SCR_012674) Copy
http://www.nitrc.org/projects/efficient_pt
A Matlab implementation for efficient permutation testing by using matrix completion.
Proper citation: Efficient Permutation Testing (RRID:SCR_014104) Copy
https://github.com/nlm-irp-jianglab/SpikeHunter
Software deep learning tool for identifying phage tailspike proteins. Used to identify phage tailspike proteins.
Proper citation: SpikeHunter (RRID:SCR_024831) Copy
https://github.com/xinhe-lab/GSFA
Software R package that performs sparse factor analysis and differential gene expression discovery simultaneously on single cell CRISPR screening data.
Proper citation: Guided Sparse Factor Analysis (RRID:SCR_025023) Copy
Software tool for analysis of non-covalent interactions in molecular dynamics trajectories. Implemented in Python and is universally applicable to any kind of MD trajectory supported by MDAnalysis package.
Proper citation: PyContact (RRID:SCR_025066) Copy
Open access knowledge base for microbial natural products discovery. Database of microbially derived natural product structures. Provides coverage of bacterial and fungal natural products to visualize chemical diversity. Includes compounds and contains referenced data for structure, compound names, source organisms, isolation references, total syntheses, and instances of structural reassignment. Interactive web portal permits searching by structure, substructure, and physical properties. Provides mechanisms for visualizing natural products chemical space and dashboards for displaying author and discovery timeline data. Atlas has been developed under FAIR principles.
Proper citation: Natural Products Atlas (RRID:SCR_025107) Copy
https://github.com/PhysiCell-Tools/PhysiCell-Studio
Software graphical tool to allow easy editing of (XML) model, create initial positions of cells, run simulation, and visualize results. To contribute, fork and make PRs to the development branch. Used to create, execute, and visualize multicellular model using PhysiCell.
Proper citation: PhysiCell Studio (RRID:SCR_025311) Copy
https://github.com/COMBINE-lab/maximum-likelihood-relatedness-estimation
C++ program to infer biological relatedness from low coverage 2nd generation sequencing data. It uses information from genotype likelihoods rather than observed genotypes in maximum likelihood framework in order to estimate the overall coefficient of relatedness as well as individual kinship components between two samples. Maximum Likelihood Estimation of Biological Relatedness from Low Coverage Sequencing Data.
Proper citation: lcMLkin (RRID:SCR_025418) Copy
http://www.bios.unc.edu/research/genomic_software/Matrix_eQTL/
Software tool for ultra fast eQTL analysis via large matrix operations.
Proper citation: MatrixEQTL (RRID:SCR_025513) Copy
https://github.com/sokrypton/ColabFold
Software application offers accelerated prediction of protein structures and complexes by combining homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. Used for protein folding.
Proper citation: ColabFold (RRID:SCR_025453) Copy
Publicly accessible 3D data repository where subject experts, educators, and general public can find, view, interact with, and download 3D and 2D media representing physical objects important to the world’s natural history, cultural heritage, and scientific collections. Media data are contributed by a community that includes museums, institutions, researchers, scholars, and other subject experts who use MorphoSource to archive data, share findings, and increase scholarly impact. Contributed media represent both biological objects such as fossils and representatives of living species, as well as artifacts and objects created by humans that are critical to our shared cultural heritage.
Proper citation: MorphoSource (RRID:SCR_025654) Copy
https://bioconductor.org/packages/release/bioc/html/SomaticSignatures.html
Software R package for identifying mutational signatures of single nucleotide variants (SNVs) from high-throughput experiments.
Proper citation: SomaticSignatures (RRID:SCR_025620) Copy
https://brainlife.io/docs/using_ezBIDS/
Web-based BIDS conversion tool to convert neuroimaging data and associated metadata to BIDS standard. Guided standardization of neuroimaging data interoperable with major data archives and platforms.
Proper citation: ezBIDS (RRID:SCR_025563) Copy
https://github.com/zhouhj1994/LinDA
Software linear models for differential abundance analysis of microbiome compositional data. Used to tackle compositional effects in differential abundance analysis. It fits linear regression models on centered log2-ratio transformed data, identifies bias term due to transformation and compositional effect, and corrects bias using mode of regression coefficients. It could fit mixed-effect models.
Proper citation: LinDA (RRID:SCR_025966) Copy
https://nationalmaglab.org/user-facilities/high-b-t-facility
Facility to conduct experiments in high magnetic fields up to 15 tesla and at very low temperatures down to 0.4 mK simultaneously. Located at University of Florida in Gainesville, it is operated as part of Physics Department Microkelvin Laboratory.
Proper citation: National High Magnetic Field Laboratory High B/T Core Facility (RRID:SCR_017360) Copy
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