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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Pythia
 
Resource Report
Resource Website
50+ mentions
Pythia (RRID:SCR_004952) software resource Pythia is an open source thermodynamically oriented primer design python module. Pythia can be used in two ways. 1. Executable binaries only: under windows with cygwin and python 2.5 (built with mingw, that comes with the cygwin release). These executables allow the user to index DNA files for primer specificity search, design one primer pair per region, and tile regions with PCR amplicons. 2. A python module: under windows with cygwin, python2.5, numpy, swig, and mingw, or under linux with python2.4 or later, numpy, and swig (everything but numpy should be pre-installed on a normal linux system). The module gets you everything that the binaries get you, in a more pythonic framework. This package also includes modules for computing DNA binding and folding energies using the partition function approach with publicly available thermodynamic data. Usage documentation is in the downloads. has parent organization: SourceForge PMID:19528077 nlx_91969 SCR_004952 2026-09-05 06:25:27 50
cortex var
 
Resource Report
Resource Website
1+ mentions
cortex var (RRID:SCR_005081) cortex_var software resource A tool for genome assembly and variation analysis from sequence data. You can use it to discover and genotype variants on single or multiple haploid or diploid samples. If you have multiple samples, you can use Cortex to look specifically for variants that distinguish one set of samples (eg phenotype=X, cases, parents, tumour) from another set of samples (eg phenotype=Y, controls, child, normal). cortex_var features * Variant discovery by de novo assembly - no reference genome required * Supports multicoloured de Bruijn graphs - have multiple samples loaded into the same graph in different colours, and find variants that distinguish them. * Capable of calling SNPs, indels, inversions, complex variants, small haplotypes * Extremely accurate variant calling - see our paper for base-pair-resolution validation of entire alleles (rather than just breakpoints) of SNPs, indels and complex variants by comparison with fully sequenced (and finished) fosmids - a level of validation beyond that demanded of any other variant caller we are aware of - currently cortex_var is the most accurate variant caller for indels and complex variants. * Capable of aligning a reference genome to a graph and using that to call variants * Support for comparing cases/controls or phenotyped strains * Typical memory use: 1 high coverage human in under 80Gb of RAM, 1000 yeasts in under 64Gb RAM, 10 humans in under 256 Gb RAM genome assembly, variation analysis, sequence, variation, genotype variant, haploid, diploid, snp, indel, inversion, variant, haplotype, de novo assembly, genotyping, variant-calling, population analysis, population assembly is listed by: OMICtools
has parent organization: SourceForge
has parent organization: Wellcome Trust Centre for Human Genetics
PMID:22231483 GNU General Public License, v3, Acknowledgement requested OMICS_00056 SCR_005081 cortex_var - for variant and population assembly 2026-09-05 06:25:29 3
Bambus
 
Resource Report
Resource Website
Bambus (RRID:SCR_005068) Bambus software resource Software for scaffolding to address some of the challenges encountered when analyzing metagenomes. Scaffolding represents the task of ordering and orienting contigs by incorporating additional information about their relative placement along the genome. While most other scaffolders are closely tied to a specific assembly program, Bambus accepts the output from most current assemblers and provides the user with great flexibility in choosing the scaffolding parameters. In particular, Bambus is able to accept contig linking data other than specified by mate-pairs. Such sources of information include alignment to a reference genome (Bambus can directly use the output of MUMmer), physical mapping data, or information about gene synteny. scaffolding is listed by: OMICtools
has parent organization: SourceForge
PMID:21926123 Open unspecified license OMICS_01432 http://sourceforge.net/apps/mediawiki/amos/index.php?title=Bambus SCR_005068 Bambus 2, Bambus 2.0 2026-09-05 06:25:29 0
G-BLASTN
 
Resource Report
Resource Website
G-BLASTN (RRID:SCR_005062) G-BLASTN software resource A GPU-accelerated nucleotide alignment tool based on the widely used NCBI-BLAST. It can produce exactly the same results as NCBI-BLAST, and it also has very similar user commands. It also supports a pipeline mode, which can fully utilize the GPU and CPU resources when handling a batch of medium to large sized queries. parallel computation 4, blast, alignment, nucleotide, gpu, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BLAST
has parent organization: Hong Kong Baptist University; Hong Kong; China
has parent organization: SourceForge
Hong Kong Baptist University; Hong Kong; China FRG2/11-12/158;
NVIDIA
PMID:24463183 Free OMICS_02263, biotools:g-blastn http://sourceforge.net/projects/gblastn/, https://bio.tools/g-blastn SCR_005062 2026-09-05 06:25:28 0
VFS
 
Resource Report
Resource Website
1+ mentions
VFS (RRID:SCR_005138) VFS software resource A versatile high-throughput sequencing (HTS) tool for discovering viral integration events and reconstruct fusion transcripts at single-base resolution. It combines soft-clipping information, read-pair analysis, and targeted de novo assembly to discover and annotate viral-human fusion events. A simple yet effective empirical statistical model is used to evaluate the quality of fusion breakpoints. Minimal user defined parameters are required. ubuntu, debian, high-throughput sequencing, virus, reconstruct, fusion transcript, transcript, integration, fusion, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23314323 GNU General Public License, v3 OMICS_00224, biotools:viralfusionseq https://bio.tools/viralfusionseq SCR_005138 ViralFusionSeq, ViralFusionSeq (VFS) 2026-09-05 06:25:30 1
COVA
 
Resource Report
Resource Website
50+ mentions
COVA (RRID:SCR_005175) COVA software resource A variant annotation and comparison tool for next-generation sequencing. It annotates the effects of variants on genes and compares those among multiple samples, which helps to pinpoint causal variation(s) relating to phenotype. next-generation sequencing, variant annotation, variant, annotation, gene, genetic variation, phenotype is listed by: OMICtools
has parent organization: SourceForge
OMICS_00171 SCR_005175 COVA - Comparison of variants and functional annotation, Comparison of variants and functional annotation 2026-09-05 06:25:31 60
QuRe
 
Resource Report
Resource Website
1+ mentions
QuRe (RRID:SCR_005209) QuRe software resource A software program for viral quasispecies reconstruction, specifically developed to analyze long read (>100 bp) next-generation sequencing (NGS) data. The software performs alignments of sequence fragments against a reference genome, finds an optimal division of the genome into sliding windows based on coverage and diversity and attempts to reconstruct all the individual sequences of the viral quasispecies--along with their prevalence--using a heuristic algorithm, which matches multinomial distributions of distinct viral variants overlapping across the genome division. QuRe comes with a built-in Poisson error correction method and a post-reconstruction probabilistic clustering, both parameterized on given error rates in homopolymeric and non-homopolymeric regions. next-generation sequencing, virus, long read, reconstruction is listed by: OMICtools
has parent organization: SourceForge
OMICS_00230 SCR_005209 qure - software for viral quasispecies reconstruction from next-gen seq. data 2026-09-05 06:25:31 6
GenoSIGHT
 
Resource Report
Resource Website
GenoSIGHT (RRID:SCR_012119) software resource An adaptive imaging cytometry software environment. standalone software is listed by: OMICtools
has parent organization: SourceForge
PMID:25210731 OMICS_05634 SCR_012119 2026-09-05 06:27:21 0
ISDTool
 
Resource Report
Resource Website
ISDTool (RRID:SCR_012125) software resource Software that implements a computational model for predicting immunosuppressive domains (ISDs). The software could be used to identify typical ISDs in retroviruses including HERV, HTLV, HIV, STLV, SIV and MLV. standalone software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:25008418 OMICS_05696, biotools:isdtool https://bio.tools/isdtool SCR_012125 2026-09-05 06:27:21 0
A5-miseq
 
Resource Report
Resource Website
100+ mentions
A5-miseq (RRID:SCR_012148) software resource Software that produces high quality microbial genome assemblies on a laptop computer without any parameter tuning. A5-miseq does this by automating the process of adapter trimming, quality filtering, error correction, contig and scaffold generation, and detection of misassemblies. Unlike the original A5 pipeline, A5-miseq can use long reads from the Illumina MiSeq, use read pairing information during contig generation, and includes several improvements to read trimming. standalone software, illumina, unix/linux, mac os x, bio.tools is used by: Nephele
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:25338718 GNU General Public License OMICS_06339, biotools:a5-miseq https://bio.tools/a5-miseq SCR_012148 2026-09-05 06:27:21 202
EC2KEGG
 
Resource Report
Resource Website
1+ mentions
EC2KEGG (RRID:SCR_012127) software resource A perl-based package to perform comparative analysis of metabolic pathways between two organisms. standalone software, perl is listed by: OMICtools
has parent organization: SourceForge
PMID:25202338 OMICS_05782 SCR_012127 2026-09-05 06:27:21 8
cnvCapSeq
 
Resource Report
Resource Website
1+ mentions
cnvCapSeq (RRID:SCR_012126) software resource Software for accurate and sensitive CNV discovery and genotyping in long-range targeted resequencing. standalone software, java is listed by: OMICtools
has parent organization: SourceForge
PMID:25228465 GNU Lesser General Public License OMICS_05722 SCR_012126 2026-09-05 06:27:21 2
eALPS
 
Resource Report
Resource Website
eALPS (RRID:SCR_012130) software resource Software that uses the genotype data in conjunction with the pooled sequence data in order to accurately estimate the proportions of the samples in the pool, even in cases where not all individuals in the pool were genotyped (eALPS-LD). standalone software is listed by: OMICtools
has parent organization: SourceForge
PMID:24144111 OMICS_05833 SCR_012130 2026-09-05 06:27:21 0
PLEK
 
Resource Report
Resource Website
100+ mentions
PLEK (RRID:SCR_012132) software resource An alignment-free software tool which uses a computational pipeline based on an improved k-mer scheme and a support vector machine (SVM) algorithm to distinguish lncRNAs from messenger RNAs (mRNAs), in the absence of genomic sequences or annotations. It is especially suitable for PacBio or 454 sequencing data and large-scale transcriptome data. standalone software, roche, pacific biosciences, unix/linux, c, python, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:25239089 GNU General Public License biotools:plek, OMICS_05839 https://bio.tools/plek SCR_012132 PLEK: predictor of long non-coding RNAs and messenger RNAs based on an improved k-mer scheme 2026-09-05 06:27:21 134
LDx
 
Resource Report
Resource Website
LDx (RRID:SCR_012131) software resource A computational software tool for estimating linkage disequilibrium (LD) from pooled resequencing data. standalone software is listed by: OMICtools
has parent organization: SourceForge
PMID:23152785 OMICS_05834 SCR_012131 2026-09-05 06:27:21 0
PrimerProspector
 
Resource Report
Resource Website
10+ mentions
PrimerProspector (RRID:SCR_012136) software resource A pipeline of software programs to design and analyze PCR primers. It is built in Python using the open-source PyCogent toolkit. standalone software, python is listed by: OMICtools
has parent organization: SourceForge
PMID:21349862 OMICS_05884 SCR_012136 2026-09-05 06:27:21 26
Musite
 
Resource Report
Resource Website
10+ mentions
Musite (RRID:SCR_012141) software resource A Java-based standalone application for predicting both general and kinase-specific protein phosphorylation sites. standalone software, java is listed by: OMICtools
has parent organization: SourceForge
PMID:20702892 OMICS_05941 SCR_012141 2026-09-05 06:27:21 13
PhosphoSiteAnalyzer
 
Resource Report
Resource Website
PhosphoSiteAnalyzer (RRID:SCR_012142) software resource A bioinformatical software tool for analyzing (quantitative) phosphoproteome datasets. The program retrieves kinase-substrate predictions from NetworKIN and contains various statistical modules for futher analysis. standalone software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:22471441 Free, Public biotools:phosphositeanalyzer, OMICS_05951 https://bio.tools/phosphositeanalyzer SCR_012142 2026-09-05 06:27:21 0
CNV Workshop
 
Resource Report
Resource Website
1+ mentions
CNV Workshop (RRID:SCR_012635) CNV Workshop software resource Software for a web-enabled platform for analyzing genome variation such as copy number variation (CNV). is listed by: OMICtools
has parent organization: SourceForge
GNU Affero General Public License OMICS_00715 SCR_012635 2026-09-05 06:27:26 1
Krona
 
Resource Report
Resource Website
50+ mentions
Krona (RRID:SCR_012785) Krona software resource Software that allows hierarchical data to be explored with zoomable pie charts. bio.tools is listed by: bio.tools
has parent organization: SourceForge
PMID:21961884 OMICS_01498, biotools:krona https://bio.tools/krona SCR_012785 Krona - Hierarchical data browser 2026-09-05 06:27:27 97

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