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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
CIBERSORT
 
Resource Report
Resource Website
1000+ mentions
CIBERSORT (RRID:SCR_016955) data analytics software, software application, software resource Software tool to provide an estimation of the abundances of member cell types in a mixed cell population, using gene expression data. Used for characterizing cell composition of complex tissues from their gene expression profiles, large scale analysis of RNA mixtures for cellular biomarkers and therapeutic targets. estimation, abundance, cell, type, mixed, population, gene, expression, data, tissue, complex, analysis, RNA, biomarker, therapeutic, target, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Stanford University; Stanford; California
B&J Cardan Oncology Research Fund ;
Damon Runyon Cancer Research Foundation ;
Doris Duke Charitable Foundation ;
Ludwig Institute for Cancer Research ;
NCI T32 CA09302;
NCI U01 CA154969;
NIAID U19 AI090019;
Siebel Stem Cell Institute ;
Thomas and Stacey Siebel Foundation ;
US Department of Defense
PMID:25822800 Not freely available for download or distribution, Available for non commercial users, Registration required biotools:CIbERSORt https://bio.tools/CIBERSORT SCR_016955 2026-09-12 01:02:54 1908
Tree-Based Pipeline Optimization Tool
 
Resource Report
Resource Website
1+ mentions
Tree-Based Pipeline Optimization Tool (RRID:SCR_017531) TPOT software resource, software toolkit Software Python package to automate building of ML pipelines by combining flexible expression tree representation of pipelines with stochastic search algorithms such as genetic programming. Automated, machine, learning, optimize, pipeline, genetic, programming NIAID R01 AI117694 Free, Available for download, Freely available SCR_017532 https://epistasislab.github.io/tpot/, https://github.com/EpistasisLab/tpot SCR_017531 Tree based Pipeline Optimization Tool 2026-09-12 01:02:55 3
BEI Resource Repository
 
Resource Report
Resource Website
100+ mentions
BEI Resource Repository (RRID:SCR_013698) biobank, material storage repository, service resource, storage service resource Central data repository that supplies organisms and reagents to the broad community of microbiology and infectious diseases researchers. biomaterial, material, reagent, microbiology, infectious diseases is listed by: NIH Data Sharing Repositories
is related to: ATCC
is related to: NIH Data Sharing Repositories
infectious disease NIAID SCR_013698 BEI Resource 2026-09-12 01:03:47 258
University of California at San Francisco Division of Experimental Medicine Flow Core Facility
 
Resource Report
Resource Website
University of California at San Francisco Division of Experimental Medicine Flow Core Facility (RRID:SCR_017903) access service resource, core facility, service resource Flow cytometry facility offering training and services including:Access to two, 17-color BD LSR II analytical instruments with High Throughput Sampler (HTS) module,Configurations:LSRII 1,LSRII 2;Help with Flow Cytometry Panel Design;Fluorofinder (access our cytometers under CFAR Immunology Core);BD Panel designer;SFGH LSRII Flow Core Protocols;LSRII Startup and Shutdown;How to run the CST calibration assay;Access to a 17-color BD FACSAria II for fluorescence-activated cell sorting (FACS);4-way tube sorting;96 well plate sorting;Index sorting;SFGH ARIA Flow Core Protocols and configuration;ARIA Startup;Determining Drop Delay;Side Stream Set Up;Clog Procedure;ARIA Shutdown Protocol;ARIA Configuration;DNA analysis with standard dyes;Analysis of CFP, GFP, YFP, mRFP, mTomato, and mCherry gene expression proteins;Calcium flux measurements using Indo-1;Training of users on the operation of instruments and experimental design through the CIL Flow Cytometry Course;Maintaining and Upgrading Instruments;Research Support Services (study design, assay selection, grant and paper writing support). Flow, cytometry, support, training, instrumentation, study, design, assay, grant, paper, service, core NIAID P30 AI027763 Open ABRF_778 SCR_017903 Flow Cytometry Core 2026-09-12 01:04:05 0
MassQL
 
Resource Report
Resource Website
1+ mentions
MassQL (RRID:SCR_025106) software resource, source code Software application for universal searching of Mass Spectrometry data. Open source MS query language for flexible and mass spectrometer manufacturer-independent mining of MS data. Implements common MS terminology to build consensus vocabulary to search for MS patterns in single mass spectrometry run. Enables set of mass spectrometry patterns to be queried directly from raw data. Mass Spectrometry data searching, mass spectrometry data, mining of MS data, common MS terminology, mass spectrometry patterns, raw data query, AMED Japan Program for Infectious Diseases Research and Infrastructure ;
Betty and Gordon Moore Foundation ;
Burroughs Wellcome Fund ;
Czech Science Foundation ;
German Ministry for Education and Research ;
German Research Foundation ;
Horizon 2020 programme of the European Union ;
Ministry of Innovative Development of the Republic of Uzbekistan ;
National Cancer Center Research and Development Fund ;
National Research Foundation of Korea ;
NIAID R15 AI137996;
NIAID R21 AI156669;
NIGMS R01 GM107550;
NIGMS R01 GM125943;
NIGMS R35 GM128690;
Novo Nordisk Foundation ;
Denmark ;
NSF ;
Swedish Research Council ;
U.S. Department of Energy Joint Genome Institute ;
University of Michigan
DOI:10.1101/2022.08.06.503000 Free, Available for download, Freely available https://pypi.org/project/massql/ SCR_025106 Mass Spec Query Language 2026-09-12 01:04:37 1
IBEX Knowledge Base
 
Resource Report
Resource Website
1+ mentions
IBEX Knowledge Base (RRID:SCR_025296) knowledge base Open, global repository as central resource for reagents, protocols, panels, publications, software, and datasets. In addition to IBEX, we support standard, single cycle multiplexed imaging (Multiplexed 2D imaging), volume imaging of cleared tissues with clearing enhanced 3D (Ce3D), highly multiplexed 3D imaging (Ce3D-IBEX), and extension of the IBEX dye inactivation protocol to the Leica Cell DIVE (Cell DIVE-IBEX). Committed to sharing knowledge related to multiplexed imaging. Antibody validation community knowledgebase. Antibody, validation, multiplexed imaging, Chan Zuckerberg Initiative ;
NCI ;
NIAID ;
Schroeder Allergy and Immunology Research Institute ;
McMaster University ;
CA ;
Wellcome Trust
Free, Freely available https://zenodo.org/records/7693279 SCR_025296 Iterative Bleaching Extends Multiplexity (IBEX) Knowledge-Base 2026-09-12 01:04:41 4
drug perturbation Gene Set Enrichment Analysis
 
Resource Report
Resource Website
1+ mentions
drug perturbation Gene Set Enrichment Analysis (RRID:SCR_025351) dpGSEA software resource, source code Software tool to detect phenotypically relevant drug targets through unique transcriptomic enrichment that emphasizes biological directionality of drug-derived gene sets. Exploratory tool to screen for possible drug targeting molecules. detect phenotypically relevant drug targets, drug-derived gene sets, transcriptomic enrichment, NHLBI T32HL007567;
NIAID P30AI036219
DOI:10.1186/s12859-020-03929-0 Free, Available for download, Freely available SCR_025351 2026-09-12 01:04:42 2
Mixed effects association testing for single cells
 
Resource Report
Resource Website
1+ mentions
Mixed effects association testing for single cells (RRID:SCR_025632) MASC software resource, source code Software tool for testing whether specified covariate influences membership of single cells in any of multiple cellular subsets while accounting for technical confounds and biological variation. specified covariate, influences membership, single cells, multiple cellular subsets, accounting for technical confounds and biological variation, Doris Duke Charitable Foundation ;
NIAID U19AI111224;
NIAMSD 1R01AR063759;
NIAMSD R01 AR064850;
NIAMSD T32 AR007530;
NIAMSD UH2AR067677;
Rheumatology Research Foundation Tobe and Stephen Malawista ;
Ruth L. Kirschstein National Research Service Award ;
William Docken Inflammatory Autoimmune Disease Fund
PMID:30333237 SCR_025632 , Mixed-effects modeling of Associations of Single Cells, Mixed-effects Association testing for Single Cells 2026-09-12 01:04:48 4
xCell
 
Resource Report
Resource Website
100+ mentions
xCell (RRID:SCR_026446) software resource, software toolkit, source code, web application Software R package for generating cell type scores and R scripts for development of xCell. Web tool that performs cell type enrichment analysis from gene expression data for immune and stroma cell types. Used for Cell types enrichment analysis. Cell types enrichment analysis, cell type, enrichment analysis, generating cell type scores and R scripts, development of xCell, Gruss Lipper Postdoctoral Fellowship ;
NCI U24 CA195858;
NIAID
PMID:29141660 Free, Available for download, Freely available http://xCell.ucsf.edu/ SCR_026446 2026-09-12 01:05:04 170
chromvar
 
Resource Report
Resource Website
10+ mentions
chromvar (RRID:SCR_026570) data analysis software, data processing software, software application, software resource, software toolkit, source code Software R package for analyzing sparse chromatin-accessibility data by estimating gain or loss of accessibility within peaks sharing the same motif or annotation while controlling for technical biases. Enables accurate clustering of scATAC-seq profiles and characterization of known and de novo sequence motifs associated with variation in chromatin accessibility. Used for analysis of sparse chromatin accessibility data from single cell or bulk ATAC or DNAse-seq data. analyzing sparse chromatin-accessibility data, analysis of sparse chromatin accessibility data, single cell, bulk ATAC, DNAse-seq data, is used by: pychromVAR Broad Institute Fellowship ;
Harvard Society of Fellows ;
NHGRI P50HG007735;
NIAID U19AI057266;
Rita Allen Foundation
PMID:28825706 Free, Available for download, Freely available SCR_026570 chromatin Variability Across Regions 2026-09-12 01:05:07 15
CytoML
 
Resource Report
Resource Website
1+ mentions
CytoML (RRID:SCR_027485) software resource, software toolkit, source code Software R package that enables cross-platform import, export, and sharing of gated cytometry data. It currently supports Cytobank, FlowJo, Diva, and R, allowing users to import gated cytometry data from commercial platforms into R. Cross-platform cytometry data sharing, cross-platform import, export, sharing, gated cytometry data, import gated cytometry data, Bill and Melinda Gates Foundation ;
NIAID UM1 AI068635;
NIGMS R01 GM118417
PMID:30551257 Free, Available for download, Freely available https://www.bioconductor.org/packages/release/bioc/html/CytoML.html SCR_027485 2026-09-12 01:05:28 6
demuxlet
 
Resource Report
Resource Website
demuxlet (RRID:SCR_027855) software application, software resource, source code Software tool that harnesses natural genetic variation to determine the sample identity of each droplet containing a single cell (singlet) and detect droplets containing two cells (doublets). Genetic multiplexing of barcoded single cell RNA-seq. Genetic multiplexing of barcoded single cell RNA-seq, harnesses natural genetic variation, NHLBI K25HL121295;
NIAID R21AI133337;
NIAMSD R01AR071522;
NIDCR R03DE025665;
NIDDK F30DK115167
PMID:29227470 Free, Available for download, Freely available SCR_027855 2026-09-12 01:05:37 0
EpiProfile
 
Resource Report
Resource Website
EpiProfile (RRID:SCR_028224) software application, software resource, source code Software tool for processing Epi-Proteomics mass spectrometry data. Discriminates isobaric histone peptides using distinguishing fragment ions in their tandem mass spectra and extracts the chromatographic area under the curve using previous knowledge about peptide retention time. Nanoflow liquid chromatography coupled with high resolution tandem mass spectrometry-based quantification tool for histone peptides, which can also be adapted to analyze nonhistone protein samples. EpiProfile 2.0 is extended version of v1.0 for enhanced quantification of histone peptides based on LC-MS/MS analysis. LC-MS/MS analysis, peptide, quantification, histone, quantification of histone peptides, quantification of histone peptides based on LC-MS/MS analysis, mass spectrometry data, NCATS TL1TR001880;
NCI CA196539;
NIAID AI118891;
NIGMS GM110174;
NIGMS T32GM008275;
UPenn Epigenetics Institute
PMID:25805797
PMID:29790754
Free, Available for download, Freely available SCR_028224 EpiProfile 2.0 2026-09-12 01:05:46 0
starCAT
 
Resource Report
Resource Website
1+ mentions
starCAT (RRID:SCR_028475) software resource, software toolkit, source code Software pipeline that improves T cell characterization by simultaneously quantifying predefined gene expression programs (scRNA-Seq) capturing activation states and cellular subsets. Used to score cells based on a fixed, multidataset catalog of Gene Expression Programs from any tissues or cell-type. T cell characterization, simultaneously quantifying predefined gene expression programs, gene expression programs, NHGRI R56HG013083;
NHGRI T32HG002295;
NHGRI U01HG012009;
NIAID P01AI148102;
NIAMS R01AR063759;
NIAMS T32AR007530
PMID:38746317 Free, Available for download, Freely available SCR_028475 starCellAnnoTator, starCellAnnoTator (starCAT) 2026-09-12 01:05:52 1
TryTripDB
 
Resource Report
Resource Website
10+ mentions
TryTripDB (RRID:SCR_028607) data or information resource, database Free online resource for data mining of genomic and functional data from these kinetoplastid parasites and is part of the VEuPathDB Bioinformatics Resource Center. Integrates functional genome scale datasets (e.g. transcript expression, protein expression, genetic variation data) and information predicted from automated bioinformatics pipelines and from manual curation. Provides a user friendly web interface and a number of tools and functions for users to conduct in silico experiments to ask questions and generate hypotheses. Researchers can also contribute their expertise via the User Comments form and Apollo annotation platform, and utilize cloud-based workspace to analyze their own data. data mining, genomic data, functional data, kinetoplastid parasites, NIAID ;
Wellcome Trust
PMID:36656904 Free, Freely available SCR_028607 2026-09-12 01:05:55 14
decontam
 
Resource Report
Resource Website
decontam (RRID:SCR_028857) software resource, software toolkit, source code Software R package for the statistical identification and removal of contaminant sequences in marker-gene (e.g. 16S rRNA) and metagenomics sequencing data. Implements frequency- and prevalence-based contaminant identification methods. Used for simple statistical identification and removal of contaminants in marker-gene and metagenomics sequencing data. Statistical identification and removal of contaminants, marker gene, metagenomics, sequencing data, NIAID R01 AI112401;
NIDCR R01 DE023113;
Stanford University
PMID:30558668 Free, Available for download, Freely available SCR_028857 2026-09-12 01:06:01 0

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