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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
A company which specializes in producing calcium-based products, particularly hydroxyapatite and tricalcium phosphate. Their activities are focussed on synthetic bone graft substitutes, sustained-release drug delivery devices, and applications of HAP for protein purification.
Proper citation: Berkeley Advanced Biomaterials Inc. (RRID:SCR_010539) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 2nd, 2022. Tissue bank and service organization for bioimplants.
Proper citation: Surgical Biologics - a MiMedx Group Company (RRID:SCR_010661) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 2nd, 2022. Manufacturer of Dermagraft, a bio-engineered skin substitute that assists in restoring damaged tissue and supports the body's natural healing process.
Proper citation: Advanced Biohealing, Inc. (RRID:SCR_010630) Copy
An online database for miRNA target prediction and functional annotations.
Proper citation: miRDB (RRID:SCR_010848) Copy
Web tool to predict biological targets of miRNAs by searching for presence of conserved 8mer, 7mer and 6mer sites that match seed region of each miRNA. Nonconserved sites are also predicted and sites with mismatches in seed region that are compensated by conserved 3' pairing. Used to search for predicted microRNA targets in mammals.
Proper citation: TargetScan (RRID:SCR_010845) Copy
https://esp.gs.washington.edu/
Project focused on understanding the contribution of rare genetic variation to heart, lung and blood disorders through the sequencing of well-phenotyped populations.
Proper citation: NHLBI Grand Opportunity Exome Sequencing Project (RRID:SCR_010798) Copy
http://archive.igbmc.fr/recherche/Prog_FGC/Eq_HGron/Polyphemus.html
R package for comparative analysis of RNA Polymerase II ChIP-Seq profiles by non-linear normalization.
Proper citation: POLYPHEMUS (RRID:SCR_010870) Copy
http://adacgh.bioinfo.cnio.es/
A web tool for the analysis of aCGH data sets. They focus on calling gains and losses and estimating the number of copy changes. Note: ADaCGH will continue being maintained, but is deprecated. Their new tool for CGH and CNV is WaviCGH, http://wavi.bioinfo.cnio.es/
Proper citation: ADaCGH (RRID:SCR_010916) Copy
http://www.zi-mannheim.de/en.html
An independent public foundation of the State of Baden-Wuerttemberg associated with the University of Heidelberg, that is one of Europe''s premier research institutions dedicated to mental health. The CIMH combines a clinical inpatient (300 beds) and outpatient program in adult psychiatry, addiction, childhood and adolescent psychiatry and psychotherapy with outstanding research facilities, including two dedicated research fMRI scanners (currently 1.5 Ts and 3 Ts, from next summer 2 3 Ts magnets), an 9.4 Ts animal fMRI scanner, high-throughput facilities for genotyping and molecular biology, neuropsychology and an extensive transgenic animal (both mice and rats) and animal behavior assessment facility.
Proper citation: Central Institute of Mental Health; Mannheim; Germany (RRID:SCR_011144) Copy
http://www.item.fraunhofer.de/en.html
Institute that offers contract research in the area of human health with a focus on airway research. The institute has pooled its competences to form six business units: Toxicology Testing; Pre-clinical Pharmacology; Early-Phase Clinical Trials; Registration and Risk Assessment; Environmental, Occupational and Consumer Protection; and Manufacturing of Biopharmaceuticals for Clinical Trials. Due to their broad spectrum of expertise, they are able to offer complete solutions from the idea to the product.
Proper citation: Fraunhofer Institute for Toxicology and Experimental Medicine (RRID:SCR_011237) Copy
An agency responsible for the evaluation and supervision of medicines developed by pharmaceutical companies for use in the European Union. Its main responsibility is the protection and promotion of public and animal health through the evaluation and supervision of medicines for human and veterinary use. The Agency also plays a role in stimulating innovation and research in the pharmaceutical sector. The Agency gives scientific advice and other assistance to companies for the development of new medicines. It publishes guidelines on quality-, safety- and efficacy-testing requirements. A dedicated SME Office provides special assistance to small and medium-sized enterprises.
Proper citation: European Medicines Agency (RRID:SCR_011215) Copy
http://www.biobankcentral.org/resource/wwibb.php
THIS RESOURCE IS NO LONGER IN SERVICE, documented on March 27, 2013. Web-based portal to connect all the constituencies in the global biobank community. The project seeks to increase the transparency and accessibility of the scientific research process by connecting researchers with an additional source of funding - microinvestments received from the broader online community. In exchange for these public investments, researchers will maintain research logs detailing the play-by-play progress made in their project, as well as publishing all of their data in a public database under a science commons license. These research projects, in turn, will serve to continually update a research-based neuroscience-based human brain & body curriculum. Biobanks are the meeting point of two major information trends in biomedical research: the generation of huge amounts of genomic and other laboratory data, and the electronic capture and integration of patient clinical records. They are comprised of large numbers of human biospecimens supplemented with clinical data. Biobanks when implemented effectively can harness the power of both genomic and clinical data and serve as a critical bridge between basic and applied research, linking laboratory to patient and getting to cures faster. As science and technology leaders work to address the many challenges facing U.S. biobanks logistical, technical, ethical, financial, intellectual property, and IT BioBank Central will serve as an accurate and timely source of knowledge and news about biorepositories and their role in research and drug development. The Web site also provides a working group venue, patient and public education programs, and a forum for international collaboration and harmonization of best practices.
Proper citation: BioBank Central (RRID:SCR_008645) Copy
http://www.rad.upenn.edu/sbia/braid/braid_web/index.html
Large-scale archive of normalized digital spatial and functional data with an analytical query mechanism. One of its many applications is the elucidation of brain structure-function relationships. BRAID stores spatially defined data from digital brain images which have been mapped into normalized Cartesian coordinates, allowing image data from large populations of patients to be combined and compared. The database also contains neurological data from each patient and a query mechanism that can perform statistical structure-function correlations. The project is developing database technology for the manipulation and analysis of 3-dimensional brain images derived from MRI, PET, CT, etc. BRAID is based on the PostgreSQL server, an object/relational DBMS, which allows a standard relational DBMS to be augmented with application-specific datatypes and operators. The BRAID project is adding operations and datatypes to support querying, manipulation and analysis of 3D medical images, including: * Image Datatypes: BRAID supports a family of 3D image datatypes, each having an abstract type and an implementation type. Abstract types include boolean (for regions of interest), integer, float, vector (for representing morphological changes), tensor (for representing derivatives and standard deviations of vector images) and color. Implementation types at present include line-segment format and voxel array. * Image Operators: BRAID supports addition of images, multiplication (which is interpreted as intersection for boolean images), coercion of an image''s abstract or implementation type to another value, and determination of volumes of regions of interest. * Statistical Operators: A chi-squared test has been added to SQL as an aggregate operator on pairs of boolean values. * Web Interface: A general-purpose Web gateway allows the results of queries that return computed images to be displayed. You can download the BRAID source code 2.0. This version is developed under postgreSQL 7.3.4., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: BRAID (RRID:SCR_008702) Copy
http://www.alzfdn.org/index.htm
Non profit organization and informational portal directed towards patients and families. AFA is an umbrella orgnization uniting over 1600 member organizations to collaborate on education, resources, best practices and advocacy. AFA provides several grant opportunities for AFA's nonprofit member organizations and to individuals in need.
Proper citation: Alzheimer's Foundation of America (RRID:SCR_008724) Copy
http://brainbank.med.miami.edu/
A biomaterial supply resource which collects and disseminates over 1500 brains and links tissue specimens to patient data. The Brain Endowment Bank distributes brain tissue specimens to scientists worldwide who are investigating neurodegenerative and neuropsychiatric diseases, as well as to scientists involved in ongoing studies on the affects of aging. Its overall objective is to support basic and clinical research activities by providing a systematic method for obtaining detailed pre-mortem clinical information, developing procedures for optimizing brain autopsies, cryopreserving neuropathological specimens, and obtaining neuropathological diagnoses after death.
Proper citation: UM Brain Endowment Bank (RRID:SCR_008721) Copy
A robust, secure, medical-grade, web application that lives in the cloud and has the ability to analyze and annotate entire human genomes in a rapid and cost-effective way.
Proper citation: Tute Genomics (RRID:SCR_008672) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 08, 2014. A multi-disciplinary institute providing specialized diagnostic evaluations, innovative treatments, education and research. It provides a collaborative, team-centered approach to provide innovative diagnostics to assist in developing cutting-edge brain based interventions and treatment strategies to best serve their patient's individual needs. Comprehensive Neuroscience Center is dedicated to working with children and adults who demonstrate neurodevelopmental disorders such as Autism Spectrum Disorders, Attention Deficits Hyperactivity Disorder, Learning Disabilities and Language-based deficits, as well as other neurological-based disorders including Traumatic brain injury, Disorders of Consciousness, Disorders of Aging, Alzheimer's and Dementia.
Proper citation: Comprehensive Neuroscience Center (RRID:SCR_008705) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 07, 2013. A multidisciplinary neuroscience laboratory in which basic and clinical scientists work side by side exploring neural mechanisms and models of mental and cognitive function and of neuropsychiatric illness. Experiments are performed at many levels of inquiry, from basic molecular biology of the gene to clinical examinations of patients. A major area of investigation of this laboratory is the genetic mechanisms implicated in the pathogenesis of schizophrenia and its treatment. The laboratory is organized as a multi-disciplinary team of investigators with a common mission: to identify and fully characterize basic genetic and neurobiological mechanisms of schizophrenia and related cognitive and emotional disorders. The various components of this effort are centered various different units or divisions represented by groups of investigators, at various levels of training and experience, working on related experiments. The Director of the Branch and of the Genes, Cognition and Psychosis Program (GCAP) is Daniel R. Weinberger, M.D. The CBDB is the principle research laboratory in the created (2003) Genes, Cognition, and Psychosis Program (GCAP) of the NIMH. After twelve years of residing on the pastoral grounds of St. Elizabeths Hospital, in Southeast Washington, CBDB moved back to the main NIH campus in Bethesda, Maryland in 1998. While the unique setting of St. Elizabeths is irreplaceable, we have occupied beautiful new laboratories and clinic spaces that were created for us, and we are in the mainstream of NIH life., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: NIMH Intramural Research Program Clinical Brain Disorders Branch (RRID:SCR_008728) Copy
http://med.emory.edu/ADRC/index.html
An Alzheimer's research center which focuses on mild cognitive impairment and early diagnosis and treatment of memory disorders. The Center hosts clinical trials in which the public can participate. Its resources for scientists include a tissue and biospecimen banking facility, the Emory neurology database, and research seminars.
Proper citation: Emory Alzheimer's Disease Research Center (RRID:SCR_008761) Copy
http://www.alzresearch.org/index.cfm
A Alzheimer's Disease Research Center (ADRC) whose goal is to conduct basic and clinical research aimed at understanding Alzheimer's disease. The Center enrolls a variety of individuals for clinical trials, evaluation and follow-up, including: normal control subjects, individuals with mild memory problems, and patients diagnosed with Alzheimer's Disease or related dementias. Researchers can request data and specimens obtained from ADRC subjects. These include blood or DNA, brain specimens, and cross-sectional or longitudinal clinical and cognitive data, all from ADRC subjects.
Proper citation: Johns Hopkins Alzheimer's Disease Research Center (RRID:SCR_008757) Copy
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