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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GENERECON
 
Resource Report
Resource Website
1+ mentions
GENERECON (RRID:SCR_009195) GENERECON software application, software resource Software application for linkage disequilibrium mapping using coalescent theory. It is based on a Bayesian Markov-chain Monte Carlo (MCMC) method for fine-scale linkage-disequilibrium gene mapping using high-density marker maps. GeneRecon explicitly models the genealogy of a sample of the case chromosomes in the vicinity of a disease locus. Given case and control data in the form of genotype or haplotype information, it estimates a number of parameters, most importantly, the disease position. (entry from Genetic Analysis Software) gene, genetic, genomic, c++, unix, linux, macos, ms-windows, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154338, biotools:generecon https://bio.tools/generecon SCR_009195 2026-07-26 09:04:45 1
HTR
 
Resource Report
Resource Website
1+ mentions
HTR (RRID:SCR_009241) HTR software application, software resource Software application for haplotype association mapping using unrelated individuals; fixed and sliding window analysis; overall tests and tests for individual haplotype effects (entry from Genetic Analysis Software) gene, genetic, genomic, c++, bash shell, ms-windows, unix, solaris, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154402, biotools:htr https://bio.tools/htr SCR_009241 Haplotype Trend Regression 2026-07-26 09:04:46 1
ImageVis3D
 
Resource Report
Resource Website
10+ mentions
ImageVis3D (RRID:SCR_009566) ImageVis3D software application, software resource, data processing software A new volume rendering program developed by the NIH/NCRR Center for Integrative Biomedical Computing (CIBC). The main design goals of ImageVis3D are: simplicity, scalability, and interactivity. Simplicity is achieved with a new user interface that gives an unprecedented level of flexibility (as shown in the images). Scalability and interactivity for ImageVis3D mean that both on a notebook computer as well as on a high end graphics workstation, the user can interactively explore terabyte sized data sets. Finally, the open source nature as well as the strict component-by-component design allow developers not only to extend ImageVis3D itself but also reuse parts of it, such as the rendering core. This rendering core, for instance, is planned to replace the volume rendering subsystems in many applications at the SCI Institute and with their collaborators. magnetic resonance, rendering is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
has parent organization: University of Utah; Utah; USA
NCRR P41-RR12553-15;
DOE DEFC0206ER25781
Free, Available for download, Freely available nlx_155776 http://www.nitrc.org/projects/imagevis3d, https://sources.debian.org/src/imagevis3d/ SCR_009566 2026-07-26 09:04:53 10
Trimmomatic
 
Resource Report
Resource Website
10000+ mentions
Trimmomatic (RRID:SCR_011848) Trimmomatic software application, software resource, data processing software Software Java pipeline for trimming tasks for Illumina paired end and single ended data. Flexible Trimmer for Illumina Sequence Data. Pair aware preprocessing tool optimized for Illumina next generation sequencing data. Includes several processing steps for read trimming and filtering. Operating systems Unix/Linux, Mac OS, Windows. trimming, task, paired, end, single, data, next, generation, sequencing, filtering, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: shovill
BLE/BMELV Verbundprojekt ;
BMBF
PMID:24695404
DOI:10.1093/bioinformatics/btu170
biotools:trimmomatic, OMICS_01097 https://omictools.com/trimmomatic-tool, https://bio.tools/trimmomatic, https://sources.debian.org/src/trimmomatic/ SCR_011848 Trimmomatic v 0.32 2026-07-26 09:05:31 21028
xia2 pipeline
 
Resource Report
Resource Website
10+ mentions
xia2 pipeline (RRID:SCR_015746) software application, software resource, data processing software Data processing software that performs X-ray diffraction data processing. It handles multi-pass, multi-wavelength data sets and supports remote access to synchrotron facilities. xray, diffraction, data processing, synchrotron, mmulti-pass, multi-wavelength, bio.tools is listed by: bio.tools
is listed by: Debian
PMID:23793152 Open Source, Available for download biotools:xia2 https://bio.tools/xia2 SCR_015746 2026-07-26 09:06:36 34
rnaQUAST
 
Resource Report
Resource Website
1+ mentions
rnaQUAST (RRID:SCR_016994) software application, software resource, data processing software Software tool for evaluating RNA-Seq assembly quality and benchmarking transcriptome assemblers using reference genome and gene database. Capable to estimate gene database coverage by raw reads and de novo quality assessment using third party software. evaluation, quality, RNA-Seq, assembly, data, transcriptome, assembler, reference, genome, gene, database, raw, read, , bio.tools uses: BUSCO
is listed by: Debian
is listed by: bio.tools
is related to: rnaSPAdes
is related to: Python Programming Language
is related to: SPAdes
EMC Research and Development Department ;
St. Petersburg State University ;
Russia
PMID:27153654 Free, Available for download, Freely available biotools:rnaQUASt https://bio.tools/rnaQUAST SCR_016994 2026-07-26 09:06:52 3
Porechop
 
Resource Report
Resource Website
1000+ mentions
Porechop (RRID:SCR_016967) software application, software resource, data processing software Software tool for finding and removing adapters from Oxford Nanopore reads. finding, removing, adapter, Oxford Nanopore, read, sequencing, data is listed by: Debian
is listed by: OMICtools
Free, Available for download, Freely available OMICS_17306 https://sources.debian.org/src/porechop/ SCR_016967 2026-07-26 09:06:53 1100
PASTEClassifier
 
Resource Report
Resource Website
10+ mentions
PASTEClassifier (RRID:SCR_017645) PASTEC software application, software resource, data processing software Software tool for automatic transposable element classification. Used for searching for structural features and similarity to classify transposable elements. Automatic, transposable, element, classification, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
French National Research Agency PMID:24786468 Free, Available for download, Freely available biotools:PAStEClassifier https://urgi.versailles.inra.fr/download/repet/PASTEClassifier-1.0.tar.gz, https://bio.tools/repet, https://bio.tools/PASTEClassifier SCR_017645 Pseudo Agent System for Transposable Elements Classification, PASTEC 2026-07-26 09:07:03 11
Sniffles
 
Resource Report
Resource Website
50+ mentions
Sniffles (RRID:SCR_017619) software application, software resource, data processing software Software tool as structural variation caller using third generation sequencing (PacBio or Oxford Nanopore). It detects all types of SVs (10bp+) using evidence from split-read alignments, high-mismatch regions, and coverage analysis. Used to avoid single molecule long read sequencing high error rates. Structural, variation, caller, third, generation, sequencing, SV, split, read, alignment, mismatch, region, analysis, error, bio.tools is listed by: bio.tools
is listed by: Debian
NHGRI R01 HG006677;
NHGRI UM1 HG008898
PMID:29713083 Free, Available for download, Freely available biotools:sniffles https://bio.tools/sniffles SCR_017619 2026-07-26 09:07:02 59
MEGAHIT
 
Resource Report
Resource Website
1000+ mentions
MEGAHIT (RRID:SCR_018551) software application, software resource, data processing software Software tool as Next Generation Sequencing assembler. Optimized for metagenomes, but also works well on generic single genome assembly (small or mammalian size) and single cell assembly. Can assemble genome sequences from metagenomic datasets of hundreds of Giga base-pairs in time and memory efficient manner on single server. NGS metagenome, Next Generation Sequencing assembler, metagenome, genome assembly, genome sequence, metagenomic dataset, giga base pairs, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
Hong Kong GRF ;
Innovation and Technology Fund
PMID:25609793
PMID:27012178
Free, Available for download, Freely available OMICS_07234, biotools:megahit https://bio.tools/megahit, https://sources.debian.org/src/megahit/ SCR_018551 MEGAHIT v0.1 2026-07-26 09:07:16 1451
gffread
 
Resource Report
Resource Website
10+ mentions
gffread (RRID:SCR_018965) software application, software resource, data processing software Open source software tool to manipulate files in GFF format. Used to convert, sort, filter, transform, or cluster genomic features. Gene annotation, transcriptome analysis, GFF file format, convert, sort, filter, transform, cluster genomic feature is listed by: Debian
is listed by: OMICtools
DOI:10.12688/f1000research.23297.1 Free, Available for download, Freely available OMICS_28050 https://github.com/gpertea/gffread, https://sources.debian.org/src/gffread/ SCR_018965 General Feature Format Read, GFF Read 2026-07-26 09:07:18 26
Pychopper
 
Resource Report
Resource Website
10+ mentions
Pychopper (RRID:SCR_018966) software application, software resource, data processing software Software tool to identify, orient and trim full length Nanopore cDNA reads. Able to rescue fused reads. cDNA reads, Nanopore cDNA reads, identify reads, orient reads, trim full length reads, Nanopore reads, rescue fused reads is listed by: Debian
is related to: Oxford Nanopore Technologies
Free, Freely available https://sources.debian.org/src/python3-pychopper/ SCR_018966 Pychopper v2 2026-07-26 09:07:25 26
rna-stability
 
Resource Report
Resource Website
1+ mentions
rna-stability (RRID:SCR_019259) software application, software resource, data processing software Software tool as parallel processing framework for large scale generation of secondary RNA structures and folding statistics for transcriptome of any species. Secondary RNA structures generation, large scale generation, RNA structures, transcriptome folding statistics, , bio.tools is listed by: bio.tools
is listed by: Debian
Free, Freely available biotools:rna-stability https://bio.tools/rna-stability SCR_019259 2026-07-26 09:07:23 1
TGS-GapCloser
 
Resource Report
Resource Website
10+ mentions
TGS-GapCloser (RRID:SCR_017633) software application, software resource, data processing software Software tool that uses long reads to enhance genome assembly. Fast and accurate gap closing software tool that uses low coverage of error-prone long reads generated by third generation sequence techniques (Pacbio, Oxford Nanopore, etc.) or preassembled contigs for large genomes. Error, prone, third, generation, sequencing, long, read, gap, closing, genome, assembly, contig, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:tGS-GapCloser https://bio.tools/TGS-GapCloser SCR_017633 2026-07-26 09:07:08 35
mosdepth
 
Resource Report
Resource Website
10+ mentions
mosdepth (RRID:SCR_018929) software application, software resource, data processing software Software command line tool for rapidly calculating genome wide sequencing coverage. Measures depth from BAM or CRAM files at either each nucleotide position in genome or for sets of genomic regions. Used for fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing quick coverage calculation for genomes and exomes. Calculating genome, wide sequencing coverage, depth measurement, BAM file, CRAM file, nucleotide position, genome, genomic region set, WGS exom, targeted sequencing, coverage calculation, exom, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NHGRI R01 HG006693;
NHGRI R01 HG009141;
NIGMS R01 GM124355;
NCI U24 CA209999
PMID:29096012 Free, Available for download, Freely available OMICS_20873, biotools:mosdepth https://bio.tools/mosdepth, https://sources.debian.org/src/mosdepth/ SCR_018929 2026-07-26 09:07:18 38
parSMURF
 
Resource Report
Resource Website
1+ mentions
parSMURF (RRID:SCR_017560) software application, software resource, data processing software Open source software package as high performance computing imbalance aware machine learning tool for genome wide detection of pathogenic variants. High, performance, computing, imbalance, aware, machine, learning, genome, wide, detection, pathogenic, variant, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:parsmurf https://bio.tools/parsmurf SCR_017560 2026-07-26 09:07:01 1
EHRtemporalVariability
 
Resource Report
Resource Website
1+ mentions
EHRtemporalVariability (RRID:SCR_018663) software application, software resource, data processing software Software R package for delineating temporal dataset shifts in electronic health records. Functions to delineate temporal dataset shifts in electronic health records through projection and visualization of dissimilarities among data temporal batches.Enables exploration and identification of dataset shifts, contributing to broadly examine and repurpose large, longitudinal datasets. Used to help ensure reliable data reuse to biomedical data users. Delineating temporal data set shift, data set shift, electronic health record, temporal variability, delineate temporal data set shift, data dissimilarities, reliable data reuse, examine data set, biomedical data reuse, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: CRAN
is related to: Shiny
DOI:10.1101/2020.04.07.20056564 Free, Available for download, Freely available biotools:ehrtemporalvariability https://cran.r-project.org/web/packages/EHRtemporalVariability/readme/README.html, https://bio.tools/ehrtemporalvariability SCR_018663 Electronic Health Records temporal variability 2026-07-26 09:07:16 3
SimVascular
 
Resource Report
Resource Website
50+ mentions
SimVascular (RRID:SCR_002686) software application, simulation software, software resource Open source software suite for cardiovascular simulation. It includes code for reading 3D images, segmenting structures, generating models and meshes, and modeling blood flow in deformable vessels. The suite also includes tools for physiologic boundary conditions, fluid structure interaction, and an accurate and efficient finite element Navier-Stokes solver. Commercial components have been used in the simulation process, and for these components, the project attempts to provide interfaces that allow substitution of open source components. The SimVascular project is derived from the ASPIRE2 software project and includes modified portions of PHASTA from RPI/SCOREC. simulation software, fluid dynamics, blood flow, cardiovascular, image-based geometric modeling, image segmentation, mesh generation, vascular, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Simtk.org
PMID:31446517 Free, Available for download, Freely available nif-0000-23311, BioTools:SimVascular, biotools:SimVascular https://bio.tools/SimVascular, https://bio.tools/SimVascular, https://bio.tools/SimVascular SCR_002686 SimVascular: Cardiovascular Modeling and Simulation 2026-07-27 09:31:32 70
NEST Simulator
 
Resource Report
Resource Website
100+ mentions
NEST Simulator (RRID:SCR_002963) NEST software application, simulation software, software resource Software tool as simulator for spiking neural network models that focuses on dynamics, size and structure of neural systems rather than on exact morphology of individual neurons. Used for any size spiking neurons networks including models of information processing, models of network activity dynamics, models of learning and plasticity. simulation, neuron, spiking, neural network, model, neural system, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: MUlti SImulation Coordinator
has parent organization: NEST Initiative
DOI:10.1007/978-1-4614-7320-6_258-5 Free, Available for download, Freely available nif-0000-00162, biotools:nest https://github.com/nest/nest-simulator, https://bio.tools/nest SCR_002963 Neural Simulation Tool, NEural Simulation Tool, nest, nest-simulator 2026-07-27 09:31:37 175
OpenWorm
 
Resource Report
Resource Website
10+ mentions
OpenWorm (RRID:SCR_014650) software application, simulation software, web application, software resource 3D web browser that allows users to simulate and dissect virtual C. elegans. Users can explore the anatomy of a virtual, 3D worm by zooming in and out, rotating the model, and viewing the worm's different layers. NeuroML format and connector are used to enhance the simulation, and supporting programs and code are available for coders. simulation, model, web application, web browser, c elegans, nematode, worm, roundworm, open source, 3d, dissect, anatomy, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: WormBase
is hosted by: GitHub
PMID:25404913
DOI:10.3389/fncom.2014.00137
Open source, Code is available on GitHub, Available on the App Store SCR_014984, biotools:OpenWorm https://bio.tools/OpenWorm SCR_014650 OpenWorm Browser, Open Worm 2026-07-27 09:34:45 21

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