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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
MARRVEL
 
Resource Report
Resource Website
10+ mentions
MARRVEL (RRID:SCR_016871) MARRVEL analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Web tool to search multiple public variant databases simultaneously and provide a unified interface to facilitate the search process. Used for integration of human and model organism genetic resources to facilitate functional annotation of the human genome. Used for analysis of human genes and variants by cross-disciplinary integration of records available in public databases to facilitate clinical diagnosis and basic research. integration, database, model, genetic, resource, functional, annotation, genome, data, analysis, dataset, rare, variant, exploration, bio.tools uses: OMIM
uses: ClinVar
uses: DECIPHER
uses: Geno2MP
uses: Database of Genomic Variants
is used by: Hypothesis Center
is listed by: bio.tools
is listed by: Debian
Baylor College of Medicine Medical Scientist Training Program ;
Belfer Foundation ;
CPRIT RP170387;
Houston Endowment ;
Huffington Foundation ;
NCI P30 CA06516;
NCRR R24 RR032668;
NHGRI U01 HG007709;
NIGMS R01 GM067761;
NIGMS R01 GM067858;
NIGMS R01 GM084947;
NIGMS R01 GM120033;
NIH Office of the Director R24 OD021997;
NIH Office of the Director R24 OD022005;
NINDS 1U54NS093793;
NINDS U54 NS093793;
NSF DMS 1263932;
Simons Foundation ;
T T Chao Family Foundation ;
The Robert and Janice McNair Foundation
PMID:28502612 Free, Public, Freely available biotools:marrvel https://bio.tools/marrvel SCR_016871 SciCrunch Registry Model organism Aggregated Resources for Rare Variant ExpLoration 2026-09-26 02:15:51 25
rnaSPAdes
 
Resource Report
Resource Website
50+ mentions
rnaSPAdes (RRID:SCR_016992) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool for assembling transcripts from RNA-Seq data. Explores surprising computational parallels between assembly of transcriptomes and single cell genomes. Suitable for all kind of organisms. Part of SPAdes package since version 3.9. assembling, transcript, RNA-Seq, data, single, cell, genome, analysis, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: SPAdes
is related to: rnaQUAST
Russian Science Foundation 14-50-00069 DOI:10.1101/420208 Free, Available for download, Freely available biotools:rnaSPAdes_autogenerated https://bio.tools/rnaSPAdes_autogenerated SCR_016992 SciCrunch Registry 2026-09-26 02:15:54 58
PathwayMatcher
 
Resource Report
Resource Website
1+ mentions
PathwayMatcher (RRID:SCR_016759) data analysis software, data processing software, network analysis software, software application, software resource Software tool for multi omics pathway mapping and proteoform network generation. Open source software writen in Java to search for pathways related to a list of proteins in Reactome. mapping, omics, data, pathways, network, analysis, proteoform, generate, Reactome, database, match, bio.tools is listed by: Galaxy
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
works with: Reactome
Bergen Research Foundation ;
European Research Council ;
NHGRI U41 HG003751;
NIGMS U54 GM114833;
Research Council of Norway
DOI:10.1101/375097 Free, Available for download, Freely available BioTools:PathwayMatcher, biotools:PathwayMatcher https://anaconda.org/bioconda/pathwaymatcher, https://toolshed.g2.bx.psu.edu/repository?repository_id=6d75f02b86acc421, https://bio.tools/PathwayMatcher, https://bio.tools/PathwayMatcher, https://bio.tools/PathwayMatcher SCR_016759 SciCrunch Registry 2026-09-26 02:15:51 1
sleuth
 
Resource Report
Resource Website
10+ mentions
sleuth (RRID:SCR_016883) data analysis software, data processing software, software application, software resource Software tool for analysis of RNA-Seq experiments for which transcript abundances have been quantified with kallisto. Used for the differential analysis of gene expression data that utilizes bootstrapping in conjunction with response error linear modeling to decouple biological variance from inferential variance. differential, analysis, RNA-Seq, data, gene, expression, bootstrapping, error, linear, modeling, decouple, biological, variance, inferential, bio.tools is listed by: Debian
is listed by: bio.tools
works with: kallisto
NHGRI R01 HG006129;
NIDDK R01 DK094699
PMID:28581496 Free, Available for download, Freely available biotools:sleuth, BioTools:sleuth https://bio.tools/sleuth, https://bio.tools/sleuth, https://bio.tools/sleuth SCR_016883 SciCrunch Registry 2026-09-26 02:15:52 28
ropls
 
Resource Report
Resource Website
10+ mentions
ropls (RRID:SCR_016888) R OPLS data analysis software, data processing software, software application, software resource Software R package for multivariate analysis and feature selection of omics data. Used for visualization, regression, classification, and feature selection of omics data where the number of variables exceeds the number of samples and with multicollinearity among variables. multivariate, analysis, feature, selection, omics, data, visualization, regression, classification, variable, exceedes, number, sample, multicollinearity, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
Free, Available for download, Freely available BioTools:ropls, biotools:ropls https://bio.tools/ropls, https://bio.tools/ropls, https://bio.tools/ropls SCR_016888 SciCrunch Registry R Orthogonal Partial Least Squares 2026-09-26 02:15:53 15
Goseq
 
Resource Report
Resource Website
100+ mentions
Goseq (RRID:SCR_017052) data analysis software, data processing software, software application, software resource Software application for performing Gene Ontology analysis on RNAseq data and other length biased data. Used to reduce complexity and highlight biological processes in genome wide expression studies. Gene, Ontology, analysis, RNAseq, data, sequencing, genome, expression, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
PMID:20132535 Free, Available for download, Freely available biotools:goseq https://bio.tools/goseq SCR_017052 SciCrunch Registry 2026-09-26 02:15:55 382
Genomic Ranges
 
Resource Report
Resource Website
1+ mentions
Genomic Ranges (RRID:SCR_017051) data analysis software, data processing software, software application, software resource, software toolkit Software R package for computing and annotating genomic ranges. Used for storing and manipulating genomic intervals and variables defined along genome. computing, annotating, genomic, range, storing, manipulating, interval, variable, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
NHGRI P41 HG004059;
NHGRI U41 HG004059;
NHLBI R01 HL086601;
NHLBI R01 HL093076;
NHLBI R01 HL094635
PMID:23950696 Free, Available for download, Freely available biotools:genomicranges https://bio.tools/genomicranges SCR_017051 SciCrunch Registry 2026-09-26 02:15:54 2
XL-mHG
 
Resource Report
Resource Website
XL-mHG (RRID:SCR_016846) xlmhg data analysis software, data processing software, software application, software resource Software Python package as a semiparametric test for enrichment in ranked lists. Used for determining gene set enrichment. semiparametric, test, enrichment, ranked, list, gene, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available BioTools:XL-mHG, biotools:XL-mHG https://bio.tools/XL-mHG, https://bio.tools/XL-mHG, https://bio.tools/XL-mHG SCR_016846 SciCrunch Registry xlminimumhypergeometric, XL-minimum HyperGeometric test, XL-minimum HyperGeometric, xlmhg, XL-mHG 2026-09-26 02:15:52 0
Bridger
 
Resource Report
Resource Website
1+ mentions
Bridger (RRID:SCR_017039) data analysis software, data processing software, software application, software resource Software package as de novo trascriptome assembler for RNA-Seq data. Framework for de novo transcriptome assembly using RNA-seq data. Can assemble all transcripts from short reads without using reference. Input RNA-Seq reads in fasta or fastq format, and ouput all assembled candidate transcripts in fasta format. Operating system Unix/Linux. de novo, transcripto, assembler, RNAseq, data, short, read, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
NCRR P20 RR016460;
NIGMS P20 GM103429;
NSFC 61272016;
NSFC 61432010
PMID:25723335 Free, Available for download, Freely available biotools:bridger, OMICS_07535 https://bio.tools/bridger SCR_017039 SciCrunch Registry 2026-09-26 02:15:55 6
RepeatFiller
 
Resource Report
Resource Website
10+ mentions
RepeatFiller (RRID:SCR_017414) alignment software, data processing software, image analysis software, software application, software resource Software tool to incorporate newly detected repeat overlapping alignments into pairwise alignment chains. It only aligns local genomic regions that are bounded by colinear aligning blocks, as provided in chains, which makes it feasible to consider all seeds including those that overlap repetitive regions. Used to improve genome alignments by incorporating previously undetected local alignments between repetitive sequences. Repeat, overlapping, alignment, pairwise, chain, local, genomic, region, colinear, block, sequence, undetected, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Max Planck Institute of Molecular Cell Biology and Genetics; Dresden; Germany
DOI:10.1101/696922 Free, Freely available biotools:RepeatFiller, BioTools:RepeatFiller https://bio.tools/RepeatFiller, https://bio.tools/RepeatFiller, https://bio.tools/RepeatFiller SCR_017414 SciCrunch Registry 2026-09-26 02:15:58 16
trimAl
 
Resource Report
Resource Website
500+ mentions
trimAl (RRID:SCR_017334) data analysis software, data processing software, software application, software resource Software tool for automated removal of spurious sequences or poorly aligned regions from multiple sequence alignment. Software package for automated alignment trimming in large scale phylogenetic analyses. removal, spurious, sequence, poorly, aligned, region, multiple, alignment, trimming, large, scale, phylogenetic, analysis, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
FIS ;
MEC
PMID:19505945 Free, Available for download, Freely available biotools:trimal https://vicfero.github.io/trimal/, https://bio.tools/trimal SCR_017334 SciCrunch Registry 2026-09-26 02:15:57 673
Human Neocortical Neurosolver
 
Resource Report
Resource Website
10+ mentions
Human Neocortical Neurosolver (RRID:SCR_017437) HNN data analysis software, data processing software, simulation software, software application, software resource Open source software package for circuit level interpretation of human EEG/MEG data. Software tool for interpreting cellular and network origin of human MEG/EEG data. Simulates electrical activity of neocortical cells and circuits that generate primary electrical currents underlying EEG/MEG recordings. Designed for researchers and clinicians, without computational neural modeling experience, to develop and test hypothesis on circuit origin of their data. Neural, modeling, human, imaging, data, EEG, MEG, electrical, neocortical, cell, circuit, BRAIN Initiative, bio.tools is recommended by: BRAIN Initiative
is listed by: Debian
is listed by: bio.tools
has parent organization: Brown University; Rhode Island; USA
has parent organization: Yale University; Connecticut; USA
has parent organization: Massachusetts General Hospital
NIBIB R01 EB022889;
NIDCD R01 DC012947
DOI:10.1101/740597 Free, Available for download, Freely available SCR_017678, biotools:HNN https://github.com/jonescompneurolab/hnn, https://github.com/jonescompneurolab/hnn/tree/0.0.5, https://github.com/jonescompneurolab/hnn/tree/0.1.2, https://zenodo.org/record/2394296#.Xg4rCEdKiM9, https://bio.tools/HNN SCR_017437 SciCrunch Registry 2026-09-26 02:15:59 13
FateID
 
Resource Report
Resource Website
1+ mentions
FateID (RRID:SCR_017244) data analysis software, data processing software, software application, software resource Software R package for inference of cell fate bias from single cell RNA-seq data. Iterative supervised learning algorithm for probabilistic quantification of cell fate bias in progenitor populations. inference, cell, fate, bias, single, RNAseq, data, iterative, supervised, learning, algorithm, probabilistic, quantification, progenitor, population, bio.tools is listed by: bio.tools
is listed by: Debian
PMID:29630061 Free, Available for download, Freely available biotools:fateid https://bio.tools/fateid SCR_017244 SciCrunch Registry 2026-09-26 02:15:56 2
GEDIT
 
Resource Report
Resource Website
10+ mentions
GEDIT (RRID:SCR_019277) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Software tool for accurate cell type quantification from gene expression data. Uses gene expression data to estimate cell type abundances. Allows user to supply custom reference matrices. bio.tools is listed by: bio.tools
is listed by: Debian
DOI:10.1101/728493 Free, Freely available biotools:gedit http://webtools.mcdb.ucla.edu/, https://bio.tools/gedit SCR_019277 SciCrunch Registry Gene Expression Deconvolution Interactive Tool 2026-09-26 02:16:16 12
Gmove
 
Resource Report
Resource Website
1+ mentions
Gmove (RRID:SCR_019132) simulation software, software application, software resource Software tool for genome annotation. Eukaryotic gene prediction tool focused on evidence supported by expressed sequences like transcripts and conserved proteins alignments. Can be used to reannotate genomes, to do comparative gene prediction and improve existing genome annotation. Can predict gene models with canonical and non-canonical splice sites. Expressed sequences, RNAseq, conserved proteins, conserved proteins alignment, genome annotation, Eukaryotic gene prediction, gene prediction, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:gmove https://github.com/institut-de-genomique/gmove, https://bio.tools/gmove SCR_019132 SciCrunch Registry Gene MOdeling using Various Evidence 2026-09-26 02:16:15 3
SoupX
 
Resource Report
Resource Website
50+ mentions
SoupX (RRID:SCR_019193) data analysis software, data processing software, software application, software resource, software toolkit Software R package for estimation and removal of cell free mRNA contamination in droplet based single cell RNA-seq data. Estimation, removal, cell free mRNA contamination, droplet based, single cell RNA-seq data, RNA-seq data, data, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:soupx https://bio.tools/soupx SCR_019193 SciCrunch Registry 2026-09-26 02:16:16 87
ReactomePA
 
Resource Report
Resource Website
50+ mentions
ReactomePA (RRID:SCR_019316) data analysis software, data processing software, data visualization software, software application, software resource Software R package provides functions for pathway analysis based on REACTOME pathway database. It implements enrichment analysis, gene set enrichment analysis and several functions for visualization. pathway analysis, REACTOME pathway, REACTOME database, enrichment analysis, gene set enrichment analysis, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
PMID:26661513 Free, Available for download, Freely available biotools:reactomepa https://bio.tools/reactomepa SCR_019316 SciCrunch Registry Reactome Pathway Analysis 2026-09-26 02:16:17 86
tradeSeq
 
Resource Report
Resource Website
10+ mentions
tradeSeq (RRID:SCR_019238) data analysis software, data processing software, software application, software resource Software tool as suite of tests for identifying dynamic temporal gene regulation using single cell RNA-seq data.Trajectory based differential expression analysis for sequencing data. Dynamic temporal gene regulation, gene regulation identifying, gene regulation, single cell RNA-seq data, differential expression analysis, sequencing data, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:tradeseq https://bioconductor.org/packages/tradeSeq/, https://bio.tools/tradeseq SCR_019238 SciCrunch Registry TRAjectory-based Differential Expression analysis for SEQuencing data 2026-09-26 02:16:16 47
ShinyGO
 
Resource Report
Resource Website
1000+ mentions
ShinyGO (RRID:SCR_019213) data access protocol, software resource, web service Software graphical gene set enrichment tool for animals and plants. Graphical web application to gain insights from gene sets. Features include graphical visualization of enrichment results and gene characteristics, and application program interface access to KEGG and STRING for retrieval of pathway diagrams and protein-protein interaction networks. Graphical gene set enrichment, animal gene, plant gene, graphical visualization, enrichment results, gene characteristics, pathway diagrams retrieval, protein interaction network, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Ensembl
is related to: STRING
is related to: KEGG
has parent organization: South Dakota State University; South Dakota; USA
PMID:31882993 biotools:ShinyGO https://bio.tools/ShinyGO SCR_019213 SciCrunch Registry ShinyGO 0.77, ShinyGO 0.80, Shiny Gene Ontology, ShinyGO v0.61 2026-09-26 02:16:16 1213
biomaRt
 
Resource Report
Resource Website
1000+ mentions
biomaRt (RRID:SCR_019214) data analysis software, data processing software, software application, software resource Software package that integrates BioMart data resources with data analysis software in Bioconductor. Can annotate range of gene or gene product identifiers including Entrez Gene and Affymetrix probe identifiers with information such as gene symbol, chromosomal coordinates, Gene Ontology and OMIM annotation. Enables retrieval of genomic sequences and single nucleotide polymorphism information, which can be used in data analysis. BioMart databases, Bioconductor, data analysis, BioMart data integration, gene annotation, gene product identifiers annotation, gene symbol retrival, chromosomal coordinates retrival, genomic sequence retrival, nucleotide polimorphism information, , bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: BioMart Project
is related to: BioMart MartView
is related to: Entrez Gene
is related to: Affymetrix
is related to: Gene Ontology
is related to: OMIM
is related to: Affymetrix
PMID:16082012 Free, Available for download, Freely available biotools:biomart https://bio.tools/biomart SCR_019214 SciCrunch Registry biomaRt v 2.42.1 2026-09-26 02:16:16 2879

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