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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
Pilon
 
Resource Report
Resource Website
1000+ mentions
Pilon (RRID:SCR_014731) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool to automatically improve draft assemblies and find variation among strains, including large event detection. FASTA files of genome along with one or more BAM files of reads aligned as input. Read alignment analysis is used to identify inconsistencies between input genome and evidence in reads, then attempts to make improvements to genome. automatically, improve, draft, assembly, variation, strain, genome, read, alignment, analysis, inconsistency, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: shovill
is hosted by: GitHub
DOI:10.1371/journal.pone.0112963
DOI:10.1371/journal.pone.0112963
Available for download, Acknowledgement requested OMICS_14553, biotools:pilon https://github.com/broadinstitute/pilon/wiki, https://bio.tools/pilon, https://sources.debian.org/src/pilon/ SCR_014731 SciCrunch Registry 2026-09-26 02:17:12 3377
RepeatModeler
 
Resource Report
Resource Website
1000+ mentions
RepeatModeler (RRID:SCR_015027) data analysis software, data processing software, sequence analysis software, software application, software resource Sequence analysis software that performs repeat family identification and creates models for sequence data. RepeatModeler utilizes RepeatScout and RECON to identify repeat element boundaries and family relationships., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence analysis, sequence repeats, repeat identification, bio.tools uses: RepeatScout
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Dfam
Institute for Systems Biology ;
NHGRI R44 HG02244;
NHGRI R01 HG002939
THIS RESOURCE IS NO LONGER IN SERVICE biotools:repeatmodeler https://bio.tools/repeatmodeler SCR_015027 SciCrunch Registry 2026-09-26 02:17:13 3249
Morpheus
 
Resource Report
Resource Website
500+ mentions
Morpheus (RRID:SCR_014975) 3d visualization software, data processing software, data visualization software, simulation software, software application, software resource Modeling and simulation environment for study of multi scale and multicellular systems. Users can construct and simulate models of gene regulation, signaling pathways, tissue patterning and morphogenesis and explore the effects of multiscale feedbacks between these processes. Morpheus can render 2D and 3D models using graphical user interface. simulation, modeling, multicellular, systems biology, cell-based models, data visualization, differential equations, reaction-diffusion systems, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Dresden University of Technology; Saxony; Germany
BMBF 0315734;
BMBF 0316169;
DFG
PMID:24443380 Free, Available for download, Freely available biotools:morpheus-framework https://gitlab.com/morpheus.lab/morpheus, https://bio.tools/morpheus-framework https://imc.zih.tu-dresden.de/wiki/morpheus SCR_014975 SciCrunch Registry 2026-09-26 02:17:16 754
MEBS: Multigenomic Entropy-Based Score
 
Resource Report
Resource Website
1+ mentions
MEBS: Multigenomic Entropy-Based Score (RRID:SCR_015708) MEBS data analysis software, data processing software, software application, software resource Open source software to evaluate, quantify, compare, and predict the metabolic machinery of interest in large ‘omic’ datasets. This protocol finds informative protein families and uses them to score metagenomic sets. metagenomics analysis, metabolism, fasta file, protein analysis, omic dataset, bio.tools is listed by: bio.tools
is listed by: Debian
Open source, Available for download biotools:mebs https://bio.tools/mebs SCR_015708 SciCrunch Registry metagenome_Pfam_score, Multigenomic Entropy-Based Score, Multigenomic Entropy-Based Score (MEBS) 2026-09-26 02:17:13 1
Candidate Genes to Inherited Diseases
 
Resource Report
Resource Website
1+ mentions
Candidate Genes to Inherited Diseases (RRID:SCR_008190) G2D analysis service resource, data analysis service, data or information resource, database, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. A database of candidate genes for mapped inherited human diseases. Candidate priorities are automatically established by a data mining algorithm that extracts putative genes in the chromosomal region where the disease is mapped, and evaluates their possible relation to the disease based on the phenotype of the disorder. Data analysis uses a scoring system developed for the possible functional relations of human genes to genetically inherited diseases that have been mapped onto chromosomal regions without assignment of a particular gene. Methodology can be divided in two parts: the association of genes to phenotypic features, and the identification of candidate genes on a chromosonal region by homology. This is an analysis of relations between phenotypic features and chemical objects, and from chemical objects to protein function terms, based on the whole MEDLINE and RefSeq databases. function, gene, genetic, chromosome, disease, disorder, genome, homology, human, phenotype, protein, region, candidate gene, database, data warehouse, data set, bio.tools is listed by: 3DVC
is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: European Molecular Biology Laboratory
has parent organization: EMBL - Bork Group
PMID:16115313 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-21162, biotools:g2d http://www.bork.embl-heidelberg.de/g2d/, http://www.ogic.ca/projects/g2d_2/, https://bio.tools/g2d SCR_008190 SciCrunch Registry G2D - Candidate Genes to Inherited Diseases, Genes2Diseases 2026-09-26 02:17:10 2
FragGeneScan
 
Resource Report
Resource Website
100+ mentions
FragGeneScan (RRID:SCR_011929) data analysis software, data processing software, sequence analysis software, software application, software resource A software application for finding fragmented genes in short reads and may be applied to predict prokaryotic genes in incomplete assemblies or complete genomes. microbiome, sequence analysis, fragment, gene, short read, bio.tools is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: bio.tools
is listed by: Debian
has parent organization: Indiana University; Indiana; USA
Acknowledgement requested, Available for download OMICS_01484, biotools:fraggenescan http://omics.informatics.indiana.edu/FragGeneScan/, https://bio.tools/fraggenescan SCR_011929 SciCrunch Registry 2026-09-26 02:17:11 190
RNA FRABASE - RNA FRAgments search engine and dataBASE
 
Resource Report
Resource Website
RNA FRABASE - RNA FRAgments search engine and dataBASE (RRID:SCR_012808) RNA FRABASE analysis service resource, d spatial image, data analysis service, data or information resource, database, production service resource, service resource Engine and database to search the three-dimensional fragments within 3D RNA structures using as an input the sequence(s) and / or secondary structure(s) given in the dot-bracket notation. The database contains RNA sequences and secondary structures, described in the dot-bracket notation, derived from PDB-deposited RNA structures and their complexes. It also contains atom coordinates of the unmodified and modified nucleotide and nucleoside residues extracted from the PDB-deposited RNA structures, as well as torsion and pseudotorsion angle values, sugar pucker parameters and classification of base pair types given for the PBD-deposited RNA structures. Knowledge of the three dimensional RNA structure is crucial for all fields of biomolecular research. In contrast to the protein field, only about 1.300 experimentally derived structures of RNAs are deposited in the Protein Data Bank (PDB). To complement the results of experimental studies, new approaches based on bioinformatics and calculation are pursued in several laboratories to make tertiary RNA structure prediction possible. RNA FRABASE version 2.0 should greatly facilitate various RNA structure modelling approaches, RNA structure analysis and motif searching. If one compares the three dimensional RNA structure to a spatial puzzle, the RNA FRABASE allows to pull out a defined piece of this puzzle - the 3D RNA fragment. The architecture of the web-accessible RNA FRABASE engine and database is based on the following information path: PDB-deposited RNA structures �� RNA sequences and secondary structures described in the dot-bracket notation �� secondary structures of RNA fragments �� 3D RNA fragments. RNA FRABASE 2.0 also stores data and conformational parameters in order to provide on the spot structural filters to explore the three-dimensional RNA structures. An instant visualization of the 3D RNA structures is provided. structural element, secondary structure, rna, rna structure, 3d rna fragment, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Polish Academy of Sciences Poznan; Poznan; Poland
Foundation for Polish Science SP 01/04;
Ministry of Education and Science 3T09A014 29;
Polish Ministry of Science and Higher Education PBZ-MniSW-07/1/2007/01;
Polish Ministry of Science and Higher Education NN 519314635
PMID:20459631
PMID:17921499
nif-0000-03413, biotools:rna_frabase https://bio.tools/rna_frabase SCR_012808 SciCrunch Registry RNA FRAgments search engine dataBASE, RNA FRAgments search engine and dataBASE, RNA FRABASE - RNA FRAgments search engine dataBASE 2026-09-26 02:17:11 0
GeMoMa
 
Resource Report
Resource Website
100+ mentions
GeMoMa (RRID:SCR_017646) simulation software, software application, software resource Software tool as homology based gene prediction program that predicts gene models in target species based on gene models in evolutionary related reference species. Utilizes amino acid sequence conservation, intron position conservation, and RNA-seq data to accurately predict protein-coding transcripts. Supports combination of predictions based on several reference species allowing to transfer high quality annotation of different reference species to target species. Homology, based, gene, prediction, model, target, evolutionary, related, reference, species, sequence, conservation, intron, position, RNAseq, data, protein, coding, transcript, bio.tools is listed by: bio.tools
is listed by: Debian
works with: GUSHR
PMID:31020559 Free, Available for download, Freely available biotools:gemoma https://bio.tools/gemoma SCR_017646 SciCrunch Registry Gene Model Mapper 2026-09-26 02:17:15 158
Roary
 
Resource Report
Resource Website
500+ mentions
Roary (RRID:SCR_018172) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool for rapid large scale prokaryote pan genome analysis. Builds large scale pan genomes, identifying core and accessory genes. Makes construction of pan genome of thousands of prokaryote samples on standard desktop without compromising on accuracy of results. Not intended for meta genomics or for comparing extremely diverse sets of genomes. Genome analysis, prokaryote pan genome, pan genome, gene identification, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
works with: Scoary
Wellcome Trust PMID:26198102 Free, Available for download, Freely available OMICS_09491, biotools:roary https://github.com/sanger-pathogens/Roary, https://bio.tools/roary, https://sources.debian.org/src/roary/ SCR_018172 SciCrunch Registry 2026-09-26 02:17:18 710
R/qtl2
 
Resource Report
Resource Website
10+ mentions
R/qtl2 (RRID:SCR_018181) data analysis software, data processing software, software application, software resource Software R package for mapping quantitative trait loci with high dimensional data and multiparent populations. Used for analysis of high dimensional data and complex crosses. Interactive software environment for mapping quantitative trait loci in experimental populations.R/qtl2 software expands scope of R/qtl software package to include multiparent populations derived from more than two founder strains, such as Collaborative Cross and Diversity Outbred mice, heterogeneous stocks, and MAGIC plant populations. High density genotyping data, molecular phenotype, gene expression, proteomics, mapping trait loci, diversity outbred mice, bio.tools is listed by: Debian
is listed by: bio.tools
NIGMS R01 GM070683;
NIGMS R01 GM074244;
NIGMS R01 GM123489
PMID:30591514 Free, Available for download, Freely available biotools:R_qtl2, SCR_020965 https://bio.tools/R_qtl2, https://kbroman.org/qtl2, https://github.com/rqtl/qtl2 SCR_018181 SciCrunch Registry QTL, R/quantitative trait loci, QTL2, Quantitative Trait Locus 2, quantitative trait loci 2, R/qtl, qtl2 2026-09-26 02:17:16 13
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) data analysis software, data processing software, sequence analysis software, software application, software resource Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
NCI R01 CA120185;
NCI R01 CA134292;
NHGRI R01 HG006102;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
the Cancer Prevention and Research Institute of Texas
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie, https://bio.tools/stringtie, https://sources.debian.org/src/stringtie/ SCR_016323 SciCrunch Registry 2026-09-26 02:17:14 4976
CMap
 
Resource Report
Resource Website
500+ mentions
CMap (RRID:SCR_016204) data or information resource, data set, database, software resource, web application Dataset of cellular signatures that catalogs transcriptional responses of human cells to chemical and genetic perturbation. CMap contains perturbagens, expression signatures, and small molecules from cell lines. data, set, connectivity, gene, expression, database, heat map, drug, tool, perturbational, perturbagen, signature, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: Broad Institute
Free for academic use, Subscription for commercial use, Available for download, Acknowledgement requested biotools:CMap https://bio.tools/CMap SCR_016204 SciCrunch Registry LINCS CMap L1000, LINCS L1000, LINCS CMap, ConnectivityMap, Connectivity Map 2026-09-26 02:17:14 789
SMARTdenovo
 
Resource Report
Resource Website
100+ mentions
SMARTdenovo (RRID:SCR_017622) alignment software, data processing software, image analysis software, software application, software resource Software tool as de novo assembler for PacBio and Oxford Nanopore data. It produces assembly from all-vs-all raw read alignments without error correction stage. Allows to read overlapping, rescue missing overlaps, identify low-quality regions and chimaera and produce better consensus. De novo, assembler, PacBio, Oxford Nanopore, data, sequence, raw, read, alignment, error, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available BioTools:SMARTdenovo, biotools:SMARtdenovo https://bio.tools/SMARTdenovo, https://bio.tools/SMARTdenovo, https://bio.tools/SMARTdenovo SCR_017622 SciCrunch Registry 2026-09-26 02:17:17 191
pheatmap
 
Resource Report
Resource Website
1000+ mentions
pheatmap (RRID:SCR_016418) pheatmap data acquisition software, data processing software, image acquisition software, software application, software resource, software toolkit Software tool as a function in R to draw clustered heatmaps for better control over graphical parameters. draw, clustered, heatmap, control, graphical, parameter, size, shape, text, bio.tools is used by: ClustVis
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
is related to: CRAN
Free, Available for download, Freely available biotools:pheatmap, OMICS_26726 https://github.com/raivokolde/pheatmap, https://cran.r-project.org/web/packages/pheatmap/pheatmap.pdf, https://bio.tools/pheatmap, https://sources.debian.org/src/r-cran-pheatmap/ SCR_016418 SciCrunch Registry pretty heatmap 2026-09-26 02:17:17 1249
MB-GAN
 
Resource Report
Resource Website
1+ mentions
MB-GAN (RRID:SCR_019289) simulation software, software application, software resource Software tool as deep learning simulation framework for simulating realistic microbiome data. Can automatically learn from given microbial abundances and compute simulated abundances that are indistinguishable from it. Metagenomics, deep learning, generative adversarial network, microbiome data simulation, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Texas at Dallas; Texas; USA
DOI:10.1101/863977 Free, Available for download, Freely available biotools:mb-gan https://bio.tools/mb-gan SCR_019289 SciCrunch Registry Microbiome Simulation via Generative Adversarial Network 2026-09-26 02:17:16 1
HH-suite
 
Resource Report
Resource Website
50+ mentions
HH-suite (RRID:SCR_016133) data analysis software, data processing software, sequence analysis software, software application, software resource, software toolkit Software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). Used for sequence-based protein function and structure prediction what depends on sequence-search sensitivity and accuracy of the resulting sequence alignments. protein, sensitive sequence search, pairwise alignment, multiple database, homologous structure, prediction, modeling, bio.tools is listed by: Debian
is listed by: bio.tools
Excellence Initiative of the Bundesministerium für Bildung und Forschung ;
Ludwig-Maximilians Universität Munich ;
the Deutsche Forschungsgemeinschaft grant SFB646
DOI:10.1186/s12859-019-3019-7 Free, Available for download, Freely available biotools:hh-suite https://bio.tools/hh-suite http://toolkit.genzentrum.lmu.de/sections/search SCR_016133 SciCrunch Registry 2026-09-26 02:17:14 53
JAMM
 
Resource Report
Resource Website
1+ mentions
JAMM (RRID:SCR_017049) data analysis software, data processing software, software application, software resource Software tool as peak finder for joint analysis of NGS replicates. Used for peak finding in next generation sequencing broad and narrow datasets like ChIP-Seq, ATAC-Seq, DNase-Seq. Can integrate information from biological replicates and assign peak boundaries accurately. peak, finder, sequencing, dataset, integrate, replicate, boundary, accurately, bio.tools is listed by: Debian
is listed by: bio.tools
Max-Delbrück-Center/New York University Exchange Program. PMID:25223640 Free, Available for download, Freely available biotools:jamm https://bio.tools/jamm SCR_017049 SciCrunch Registry J oint A nalysis of NGS replicates via M ixture M odel clustering, Joint Analysis of NGS replicates via Mixture Model clustering 2026-09-26 02:17:17 2
REDIportal
 
Resource Report
Resource Website
10+ mentions
REDIportal (RRID:SCR_018490) atlas, data or information resource, database, portal, service resource, topical portal Comprehensive database of A-to-I RNA Editing Events. Atlas of A-to-I RNA editing events in human and other organisms. Collection of A-to-I events in body sites of healthy individuals from GTEx project. RNA Editing sites can be searched by genomic region, gene name and other relevant features as tissue of origin. Query results are shown in sortable and downloadable tables in which main characteristics of individual RNA editing events are reported. RNA-Seq and DNA-Seq coverage per site as well as RNA editing levels are provided. A-to-I RNA Editing Events, RNA editing events collection, atlas, database, GTEx project, genomic region, gene name, RNAseq, DNAseq, , bio.tools is listed by: Debian
is listed by: bio.tools
is related to: CLAIRE
is related to: SIGNOR
Consiglio Nazionale delle Ricerche ;
Italian Ministero dell Istruzione
PMID:27587585 Free, Freely available biotools:rediportal https://bio.tools/rediportal SCR_018490 SciCrunch Registry 2026-09-26 02:17:18 37
NetPhos
 
Resource Report
Resource Website
100+ mentions
NetPhos (RRID:SCR_017975) analysis service resource, data access protocol, production service resource, service resource, software application, software resource, standalone software, web service Web tool as artificial neural network method that predicts phosphorylation sites in independent sequences. Web application based on determination of activity of protein kinases using in vitro assays with either naturally occurring peptides or synthetic peptides. NetPhos 3.1 server predicts serine, threonine or tyrosine phosphorylation sites in eukaryotic proteins using ensembles of neural networks. Both generic and kinase specific predictions are performed. Generic predictions are identical to predictions performed by NetPhos 2.0. Kinase specific predictions are identical to predictions by NetPhosK 1.0. NetPhos 3.1 is available as stand-alone software package. Neural network, predict, phosphorylation site, independent sequence, protein, kinase, serine, threonine, tyrosine, eukaryotic, bio.tools is used by: YinOYang
is listed by: Debian
is listed by: bio.tools
has parent organization: Technical University of Denmark; Lyngby; Denmark
PMID:10600390 Free, Freely available biotools:netphos https://bio.tools/netphos http://www.cbs.dtu.dk/services/NetPhos-2.0/ SCR_017975 SciCrunch Registry NetPhos 3.1, NetPhos 2.0 2026-09-26 02:17:15 448
NanoPipe
 
Resource Report
Resource Website
1+ mentions
NanoPipe (RRID:SCR_016852) NanoPipe analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, web service Web tool for analysis of MinION (ONT) long sequencing reads. Used for analysis of reads generated by the Oxford Nanopore sequencing devices. Provides alignments to any target of interest, alignment statistics and information about polymorphisms. analysis, MinION, long, sequence, read, Oxford Nanopore, alignment, target, statistics, polymorphism, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Muenster; Muenster; Germany
Institute of Bioinformatics Muenster ;
Germany
PMID:30689855 Free, Available for download, Freely Available biotools:NanoPipe https://github.com/IOB-Muenster/nanopipe2, https://bio.tools/NanoPipe SCR_016852 SciCrunch Registry NanoPipe, nanopipe2 2026-09-26 02:17:14 5

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