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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Hypothesis Testing and Power Calculations for Comparing Metagenomic Samples from HMP
 
Resource Report
Resource Website
Hypothesis Testing and Power Calculations for Comparing Metagenomic Samples from HMP (RRID:SCR_014612) software resource An R-package which uses Dirichlet-Multinomial distribution to perform formal hypothesis testing on the species abundance distribution of human microbiome data, and to calculate power and sample size requirements for human microbiome experiments. microbiome, r, hypothesis testing, human microbiome, dirichlet multinomial distribution is listed by: Human Microbiome Project SCR_014612 2026-09-05 06:27:49 0
Hierarchical Clustering
 
Resource Report
Resource Website
1+ mentions
Hierarchical Clustering (RRID:SCR_014673) data analysis software, data processing software, software application, software resource, source code R documentation for hierarchical cluster analysis on a set of dissimilarities for n objects. Each object is assigned to its own cluster, which an algorithm proceeds through iteratively. Two of the most similar clusters are joined at each stage until there is a single cluster. Distances between clusters are recomputed at each stage by the Lance–Williams dissimilarity update formula according to the particular clustering method being used. Clustering methods include: Ward's minimum variance method, complete linkage method, and single linkage method. statistical analysis, statistical analysis package, r, r package, data analysis, software, cluster, hierarchical, dissimilarity, clustering method, metabolomics is listed by: Metabolomics Workbench Acknowledgement requested SCR_014673 R: Hierarchical Clustering, R - Hierarchical Clustering 2026-09-05 06:27:49 4
Zeitzeiger
 
Resource Report
Resource Website
10+ mentions
Zeitzeiger (RRID:SCR_014791) data acquisition software, data processing software, software application, software resource R package for regularized supervised learning on high-dimensional data from an oscillatory system. Zeitzeiger can quantify rhythmic behavior, make accurate predictions, identify major patterns and important features, and detect when the oscillator is perturbed. r, data acquisition software, rhythm, behavior, predict, oscillatory system, high dimensional data, regularized supervised learning Available for download SCR_014791 ZeitZeiger 2026-09-05 06:27:51 13
Principal Components Analysis
 
Resource Report
Resource Website
10+ mentions
Principal Components Analysis (RRID:SCR_014676) data analysis software, data processing software, software application, software resource, source code R documentation for a function that performs a principal components analysis on a given data matrix and returns the results as an object of class prcomp. statistical analysis, statistical analysis package, r, r package, principal component analysis, data matrix, prcomp, metabolomics is listed by: Metabolomics Workbench SCR_014676 2026-09-05 06:27:49 17
Linear Discriminant Analysis
 
Resource Report
Resource Website
Linear Discriminant Analysis (RRID:SCR_014675) data analysis software, data processing software, software application, software resource, source code R documentation for a function to perform linear discriminant analysis; specifically, to detect if the within-class covariance matrix is singular. statistical analysis, statistical analysis package, r, r package, linear disciminant analysis, covariance, matrix, linear discriminant analysis, data analysis software, metabolomics is listed by: Metabolomics Workbench SCR_014675 2026-09-05 06:27:49 0
oligo
 
Resource Report
Resource Website
1000+ mentions
oligo (RRID:SCR_015729) data analysis software, data processing software, software application, software resource, source code Software package to analyze oligonucleotide arrays (expression/SNP/tiling/exon) at probe-level. It currently supports Affymetrix (CEL files) and NimbleGen arrays (XYS files). oligonucleotide, microarray gene expression, r, oligonucleotide array, snp, gene expression, probe-level, affymetrix array, cel file, and nimblegen array, xys file, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
CAPES (Coordenação de Aprimoramento Pessoal de Nível Superior) ;
NCRR R01RR021967;
NHGRI P41HG004059
PMID:20688976 Free, Available for download, Runs on Mac OS, Runs on Windows biotools:oligo https://bio.tools/oligo SCR_015729 oligo package 2026-09-05 06:27:58 1808
R package: LMERConvenienceFunctions
 
Resource Report
Resource Website
1+ mentions
R package: LMERConvenienceFunctions (RRID:SCR_015658) data analysis software, data processing software, data visualization software, software application, software resource, software toolkit Software package that performs backward selection of fixed effects, forward fitting of the random effects, and post-hoc analysis using parallel capabilities. Other functionality includes the computation of ANOVAs with upper- or lower-bound p-values and R-squared values for each model term, model criticism plots, data trimming on model residuals, and data visualization. r, fixed effect, random effect, anova, p-value, r-squared, data trimming, data visualization is listed by: CRAN Free, Available for download SCR_015658 LMERConvenienceFunctions, Package ‘LMERConvenienceFunctions’, LMERConvenienceFunctions: Model Selection and Post-hoc Analysis for (G)LMER Models 2026-09-05 06:27:57 5
R package: lattice
 
Resource Report
Resource Website
10+ mentions
R package: lattice (RRID:SCR_015662) data processing software, data visualization software, software application, software resource Data visualization software inspired by Trellis graphics, with an emphasis on multivariate data. Lattice is sufficient for typical graphics needs as well as most nonstandard requirements. r, r package, multivariate data, data visualization is listed by: CRAN Free, Available for download SCR_015662 lattice, lattice: Trellis Graphics for R, Package ‘lattice’ 2026-09-05 06:27:57 13
NAPR: Neuroanatomical Age Prediction using R
 
Resource Report
Resource Website
1+ mentions
NAPR: Neuroanatomical Age Prediction using R (RRID:SCR_015759) NAPR data repository, service resource, storage service resource Cloud-based framework that allows users to estimate the age of individual subjects using cortical thickness maps derived from their own locally processed T1-weighted whole brain MRI scans. The provided age prediction models were trained using (i) relevance vector machines and (ii) Gaussian processes machine learning methods applied to cortical thickness surfaces obtained using Freesurfer v5.3. neuroanatomy, prediction, r, neuroimaging, mri scan, cortical thickness, relevance vector DOI:10.1101/099309 Free, Available for download http://www.cloudneuro.org/ SCR_015759 Neuroanatomical Age Prediction using R 2026-09-05 06:27:59 1
statsmodel
 
Resource Report
Resource Website
100+ mentions
statsmodel (RRID:SCR_016074) data analysis software, data processing software, software application, software resource Statistical software that provides classes and functions for the estimation of many different models, as well as for conducting statistical tests, and statistical data exploration. The results are tested against existing statistical packages to ensure that they are correct. http://conference.scipy.org/proceedings/scipy2010/seabold.html python, statistic, estimate, econometric, model, library, class, function, r Open source, Available for download SCR_016074 Statsmodels: Econometric and Statistical Modeling with Python 2026-09-05 06:28:03 253
HyPhy
 
Resource Report
Resource Website
1000+ mentions
HyPhy (RRID:SCR_016162) data analysis software, data processing software, sequence analysis software, software application, software resource, software toolkit Open source software package for comparative sequence analysis using stochastic evolutionary models. Used for analysis of genetic sequence data in particular the inference of natural selection using techniques in phylogenetics, molecular evolution, and machine learning. analysis, genetic, sequence, multiply, alignment, rate, pattern, data, evolution, platform, python, r, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NIGMS R01 ;
NIH R01 AI47745;
NIH U01 AI43638;
NSF DBI-0096033;
NSF DEB-9996118;
University of California Universitywide AIDS Research Program IS02-SD-701;
University of California ;
San Diego Center for AIDS Research/NIAID Developmental Award 2 P30 AI36214
PMID:15509596 Free, Available for download, Freely available SCR_016271, biotools:HyPhy, OMICS_04235 https://sources.debian.org/src/hyphy-pt/, https://veg.github.io/hyphy-site/, https://github.com/veg/hyphy, https://bio.tools/HyPhy, SCR_016162 HyPhy:Hypothesis Testing using Phylogenies, Hyphy-pt 2026-09-05 06:28:04 1586
zUMIs
 
Resource Report
Resource Website
100+ mentions
zUMIs (RRID:SCR_016139) data analysis software, data processing software, software application, software resource Software pipeline to process RNA-seq data with UMIs. The input to this pipeline is paired-end fastq files, where one read contains the cDNA sequence and the other read contains UMI and Cell Barcode information. single-cell, RNA-seq, UMI, Genomics, shell, r, perl, rna, cdna, cell, sequencing, bio.tools is listed by: bio.tools
is listed by: Debian
DOI:10.1101/153940 Open source, Free, Available for download biotools:zumis https://bio.tools/zumis SCR_016139 zumi 2026-09-05 06:28:04 128
GC/GCF
 
Resource Report
Resource Website
1+ mentions
GC/GCF (RRID:SCR_009075) software application, software resource Software application where GC implements the genomic control models. GCF implements the basic Genomic Control approach, but adjusts the p-values for uncertainty in the estimated effect of substructure. This approach is preferable if a large number of tests will be evaluated because it provides a more accurrate assessment of the significance level for small p-values. (entry from Genetic Analysis Software) gene, genetic, genomic, r, linux is listed by: Genetic Analysis Software SCR_000846, nlx_154072, nlx_154584 SCR_009075 R/GCF, R/GC, Genomic Control 2026-09-05 06:31:55 1
COVIBD
 
Resource Report
Resource Website
COVIBD (RRID:SCR_009155) software application, software resource Software application that refines linkage analysis of affected sibpairs by considering attributes or environmental exposures thought to affect disease liability. This refinement utilizes a mixture model in which a disease mutation segregates in only a fraction of the sibships, with the rest of the sibships unlinked. Covariate information is used to predict membership within the two groups corresponding to the linked and unlinked sibships. The pre-clustering model uses covariate information to first form two probabilistic clusters and then tests for excess IBD-sharing in the clusters. The Cov-IBD model determines probabilistic group membership by joint consideration of covariate and IBD values. (entry from Genetic Analysis Software) gene, genetic, genomic, r is listed by: Genetic Analysis Software nlx_154207, SCR_009109, nlx_154275 SCR_009155 R/COVIBD 2026-09-05 06:31:55 0
metaMA
 
Resource Report
Resource Website
metaMA (RRID:SCR_000408) software resource, software toolkit Software R package for meta-analysis for microarrays. It combines either p-values or modified effect sizes from different studies to find differentially expressed genes. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
is listed by: CRAN
is related to: SMAGEXP
Scottish Government Rural and Environment Research and Analysis Directorate PMID:19628502 Free, Available for download, Freely available OMICS_03524 SCR_000408 Meta-analysis for MicroArrays, Meta analysis for MicroArrays 2026-09-05 06:32:21 0
ADEGENET
 
Resource Report
Resource Website
10+ mentions
Issue
ADEGENET (RRID:SCR_000825) ADEGENET software application, software resource Software package dedicated to the handling of molecular marker data for multivariate analysis. This package is related to ADE4, a R package for multivariate analysis, graphics, phylogeny and spatial analysis. (entry from Genetic Analysis Software) gene, genetic, genomic, r is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: OMICtools
PMID:21926124
PMID:18397895
DOI:10.1093/bioinformatics/btn129
Free, Available for download, Freely available nlx_153996, nlx_154580, OMICS_11078, SCR_007239 http://adegenet.r-forge.r-project.org/, https://sources.debian.org/src/r-cran-adegenet/ SCR_000825 R/ADEGENET 2026-09-05 06:32:22 22
VennDiagram
 
Resource Report
Resource Website
1000+ mentions
VennDiagram (RRID:SCR_002414) software resource, software toolkit Software providing a set of functions to generate high-resolution Venn and Euler plots. Includes handling for several special cases, including two-case scaling, and extensive customization of plot shape and structure. Venn and Euler plots, mac os x, unix/linux, windows, r is listed by: OMICtools
is listed by: Debian
is related to: jVenn
has parent organization: CRAN
PMID:21269502 Free, Available for download, Freely available OMICS_05570 https://sources.debian.org/src/r-cran-venndiagram/ SCR_002414 VennDiagram: Generate high-resolution Venn and Euler plots 2026-09-05 06:32:26 2138
MUMA
 
Resource Report
Resource Website
10+ mentions
MUMA (RRID:SCR_002412) MUMA software application, software resource, standalone software Software that provides guidelines for the whole process of metabolomic data interpretation, from data pre-processing, to dataset exploration and visualization, to identification of potentially interesting metabolites. Guidelines outline the following processes: preprocessing of high-throughput data (normalization and scalings); principal component analysis with help tool for choosing best-separating principal components and automatic testing for outliers; automatic univariate analysis for parametric and non-parametric data, with generation of specific reports (volcano and box plots); partial least square discriminant analysis (PLS-DA); orthogonal partial least square discriminant analysis (OPLS-DA); Statistical Total Correlation Spectroscopy (STOCSY); and Ratio Analysis Nuclear Magnetic Resonance (NMR) Spectroscopy (RANSY). standalone software, mac os x, unix/linux, windows, r, metabolomics, univariate, multivariate, data analysis is listed by: OMICtools
has parent organization: CRAN
Free, Available for download, Freely available OMICS_03370 SCR_002412 Metabolomics Univariate and Multivariate Analysis (MUMA), Metabolomic Univariate and Multivariate Analysis 2026-09-05 06:32:26 28
nondetects
 
Resource Report
Resource Website
1+ mentions
nondetects (RRID:SCR_001702) software application, software resource, standalone software Software R package to model and impute non-detects in results of qPCR experiments.Used to directly model non-detects as missing data. mac os x, unix/linux, windows, r, assay domain, gene expression, preprocessing, technology, workflow step, qpcr, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Edelman-Gardner Foundation ;
NCI CA009363;
NCI CA138249;
NHGRI HG006853
PMID:24764462 Free, Available for download, Freely available OMICS_03938, biotools:nondetects https://bio.tools/nondetects SCR_001702 nondetects - Non-detects in qPCR data 2026-09-05 06:32:25 1
cortex
 
Resource Report
Resource Website
100+ mentions
cortex (RRID:SCR_002467) cortex software application, software resource Software package with functions that will help researchers plan how many subjects per group need to be included in an MRI-based cortical thickness study to ensure a thickness difference is detected. The package requires cortical thickness mapping and co-registration to be carried out using Freesurfer. The power analyses are implemented in the R software package., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. clinical neuroinformatics, mgh/mgz, magnetic resonance, r, surface analysis, thickness, mri, cortical thickness, morphometry, neuroimaging, power analysis, study design, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: bio.tools
is listed by: Debian
has parent organization: Brain Research Institute
PMID:22807270 THIS RESOURCE IS NO LONGER IN SERVICE nlx_155842, biotools:cortex http://brain.org.au/software/cortex/power, http://www.nitrc.org/projects/cortex, https://bio.tools/cortex SCR_002467 Sample Size Estimates for Well-Powered Cross-Sectional Cortical Thickness Studies 2026-09-05 06:32:27 374

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