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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 10th,2023. Commercial provider of cognitive assessments, including their proprietary database, the Brain Resource International Database (BRID) that allows users to quantify individual differences in brain function, compare individual performance against peers, and provide a robust frame of reference for clinical assessment and treatment decisions. Database provides evidence for brain behavior connection so important to reliably enabling optimal solutions for mental health and wellbeing. It powers all Brain Resource products.
Proper citation: Brain Resource (RRID:SCR_006172) Copy
NASA leads the nation on a great journey of discovery, seeking new knowledge and understanding of our planet Earth, our Sun and solar system, and the universe out to its farthest reaches and back to its earliest moments of existence. NASA's Science Mission Directorate (SMD) and the nation's science community use space observatories to conduct scientific studies of the Earth from space to visit and return samples from other bodies in the solar system, and to peer out into our Galaxy and beyond. NASA's science program seeks answers to profound questions that touch us all: * How and why are Earth's climate and the environment changing? * How and why does the Sun vary and affect Earth and the rest of the solar system? * How do planets and life originate? * How does the universe work, and what are its origin and destiny? * Are we alone? This is NASA's science vision: using the vantage point of space to achieve with the science community and our partners a deep scientific understanding of our planet, other planets and solar system bodies, the interplanetary environment, the Sun and its effects on the solar system, and the universe beyond. In so doing, we lay the intellectual foundation for the robotic and human expeditions of the future while meeting today's needs for scientific information to address national concerns, such as climate change and space weather. At every step we share the journey of scientific exploration with the public and partner with others to substantially improve science, technology, engineering and mathematics (STEM) education nationwide.
Proper citation: NASA Science (RRID:SCR_005080) Copy
http://ccr.coriell.org/Sections/Collections/CHDI/?SsId=45
HD Community BioRepository is a secure, centralized repository that stores and distributes quality-controlled, reliable research reagents. This repository currently provides access to huntingtin DNAs, polyclonal antibodies (with antigenic peptides) and cell lines. Monoclonal antibodies and hybridomas will be added in the near future. Working together with the Coriell Institute for Medical Research, CHDI Foundation established this secure, centralized repository to store and distribute quality-controlled and reliable research reagents to give research scientists unobstructed access to biomaterials and to support the discovery of therapeutics that will slow or prevent Huntington's disease. Huntington's disease is a fatal, familial disease caused by a mutation in the huntingtin gene. The mutation causes brain cells to malfunction, resulting in cognitive and physical impairments that, over the course of the disease, isolate and constrain the individual. There is currently no way to stop or reverse the course of Huntington's disease. Researchers currently not collaborating with CHDI Foundation may request these Huntington's disease resources from the HD Community BioRepository through the website; CHDI collaborators are asked to contact Mithra Mahmoudi at CHDI Management. Materials will be sent after completing a simple online MTA. Recipients are asked to cover the costs of shipping and handling. Persons with Huntington's disease bioresources interested in making them available to the research community through the HD Community BioRepository should also contact CHDI Management.
Proper citation: HD Community BioRepository (RRID:SCR_004621) Copy
http://www.acceleratedcure.org/index.php
A national nonprofit organization dedicated to accelerating the cure of MS by facilitating research that determines the causes and mechanisms of MS. Our main effort is the creation of a large-scale, multidisciplinary MS Repository of blood samples and data from people with MS and matched controls. We make these samples available to researchers investigating the causes of MS and other demyelinating diseases. In exchange for access to the repository, researchers agree to return the data they generate from the samples so that results from disparate experiments can be combined. We are also developing a Cure Map to establish and document what is known and what is not known about the causes of MS. From the Cure Map, Accelerated Cure Project will facilitate the research most likely to reveal the causes of MS in the shortest time through use of our MS Repository.
Proper citation: Accelerated Cure Project for Multiple Sclerosis (RRID:SCR_004743) Copy
Public data warehouse for searching cell line data extracted from both ATCC and HyperCLDB. The knowledge base uses the Cell Line Ontology, created with the Protege ontology editing tool from the National Center for Biomedical Ontologies (NCBO) and merges concepts from other ontologies, including the Cell Type Ontology. The Cell Line Knowledge Base uses our Cell Line Ontology as the underlying data model. The ontology defines the following cell line attributes: Cell Line ID, Organism, Tissue, Pathology, Growth Mode, MeSH ID. To report errors in the data or to add cell line data to the knowledge base, please email: clbk-data (at) umich.edu
Proper citation: Cell Line Knowledge Base (RRID:SCR_005832) Copy
http://ccr.coriell.org/Sections/Collections/AUTISM/?SsId=13
A genetic resource to support the study of autism in families where more than one child is affected or where one child is affected and one demonstrates another significant and related developmental disorder. An open bank of anonymously collected materials documented by a detailed clinical diagnosis forms the basis of this growing database of information about the disease. The Autism Resource is housed at the Coriell Institute for Medical Research in New Jersey, which holds the world''s largest collection of human cells for use in genetic research. The Autism Research Resource has been built through a full collaboration between Coriell and clinical services at the UMDNJ-Robert Wood Johnson Medical school, New Brunswick campus, which provides clinical information and diagnosis. All clinical interviews were conducted face-to-face. Further multiplex families will be added to the resource in a continuing program of diagnosis and Repository development. The Autism Research Resource includes cell lines and DNA from families with more than one child who meets criteria for autistic disorder. An additional group of families is included in which monozygotic twins meet all criteria for autistic disorder. Also included in this resource, however, are families in which one child meets the criteria for autistic disorder while another child displays behavior with a broader phenotype of falling within the spectrum of autistic disorder. A small number of multiplex families is included in which one child meets all criteria for autistic disorder and a second has a behavioral disorder falling outside the autism spectrum. Pedigrees are provided for each family. Where clinical statements are noted for individuals other than the affected children and parent(s), these should be judged as reported. All family relationships have been verified by confirming the molecular identities, established using a panel of six microsatellite markers.
Proper citation: Autism Research Resource (RRID:SCR_004623) Copy
http://cmbn-approd01.uio.no/zoomgen/hippocampus/home.do
An interactive reference atlas providing a systematic overview of cyto- and chemoarchectonical features of the hippocampus proper, fasciola, and associated parahippocampal cortices. This atlas system has been developed to serve the need to integrate detailed descriptions of structures and criteria defining boundaries and atlas images in which the underlying histological features can be explored. Features * Alphabetical and hierarchical overview of 18 hippocampal structures * Detailed, illustrated descriptions of 63 boundaries * Interactive image repository with ~100 coronal histological images stained for NeuN, calbindin, and parvalbumin * Triple image viewer in which differently stained neighboring sections can be interactively compared * Graphical overlay of substructures based on described boundary criteria * Bidirectional links between structure descriptions and image repository The atlas is based on histological material from an adult Long Evans rat, stained for NeuN, calbindin, and parvalbumin. The system is intended for researchers working in the field, as well as students interested in this brain region. The atlas is accessed through the structure index or image viewer. Re-use of data from this repository is allowed provided that reference is given to the publication.
Proper citation: Rat Hippocampus Atlas (RRID:SCR_005552) Copy
http://amide.sourceforge.net/index.html
Software tool for viewing, analyzing, and registering volumetric medical imaging data sets. It has been written on top of GTK+ and runs on any system that supports this toolkit (Linux, Windows, Mac OS X, etc.). The program incorporates automatic non-orthogonal data reslicing, allowing multiple data set to be fused without imposed constraints on the dimensions, anisotrophy, or voxel sizes of the data. Additional features include 3D ROI (ellipses, cylinders, boxes, and isocontours), multi-slice viewing, volume rendering, and data importing through the (X)MedCon library.
Proper citation: amide (RRID:SCR_005940) Copy
European research collaboration aimed at understanding the ways in which researchers are evaluated by their peers and by institutions, and at assessing how the science system can be improved and enhanced. This FP7 project is a cooperation among nine European research institutes with Professor Paul Wouters (CWTS ����?? Leiden University) as principal investigator.
Proper citation: Acumen Consortium (RRID:SCR_006599) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 1, 2022. Organization whose mission is to build and promote a sustainable ecosystem of professional societies, funding agencies, foundations, companies, and citizens together with life science researchers and innovators in computing, infrastructure and analysis with the expressed goal of translating new discoveries into tools, resources and products.
Proper citation: DELSA (RRID:SCR_006231) Copy
The NCGC Pharmaceutical Collection (NPC) is a comprehensive, publically-accessible collection of approved and investigational drugs for high-throughput screening that provides a valuable resource for both validating new models of disease and better understanding the molecular basis of disease pathology and intervention. The NPC has already generated several useful probes for studying a diverse cross section of biology, including novel targets and pathways. NCGC provides access to its set of approved drugs and bioactives through the Therapeutics for Rare and Neglected Diseases (TRND) program and as part of the compound collection for the Tox21 initiative, a collaborative effort for toxicity screening among several government agencies including the US Environmental Protection Agency (EPA), the National Toxicology Program (NTP), the US Food and Drugs Administration (FDA), and the NCGC. Of the nearly 2750 small molecular entities (MEs) that have been approved for clinical use by US (FDA), EU (EMA), Japanese (NHI), and Canadian (HC) authorities and that are amenable to HTS screening, we currently possess 2,400 as part of our screening collection. The NPC resource currently consists of (i) the physical collection suitable for high throughput screening (HTS) and (ii) the informatics browser and database. Putting together the physical collection has been surprisingly challenging in terms of the time and effort required in the informatics, compound management and synthetic chemistry related activities required for this endeavor. We provide access to the NPC screening library through collaboration. Please contact our Scientific Director Dr. Chris Austin for additional information. The other half of the NPC resource is the NPC browser. This is a self-contained software that is actively developed and maintained by the informatics group to provide electronic access to the NPC content. The latest version of the NPC browser for various platforms can be downloaded.
Proper citation: NCGC Pharmaceutical Collection (RRID:SCR_006909) Copy
http://www.ngfn.de/en/start.html
The program of medical genome research is a large-scale biomedical research project which extends the national genome research net (NGFN) and will be funded by the federal ministry of education and research (BMBF) from 2008-2013. Currently the program includes two fields: * Research ** NGFN-Plus: With the aim on combating diseases that are central to health policy, several hundred researchers are systematically investigating the complex molecular interactions of the human body. They are organized in 26 Integrated Genome Research Networks. * Application ** NGFN-Transfer: The rapid transfer of results from medical genome research into medical and industrial application is the aim of the scientists from research institutes and biomedical enterprises that cooperate in eight Innovation Alliances. AREAS OF DISEASE * Cardiovascular disease * Cancer * Neuronal diseases * Infections and Inflammations * Environmental factors
Proper citation: National Genome Research Network (RRID:SCR_006626) Copy
https://www.guidetopharmacology.org/nciuphar.jsp
Issues guidelines for nomenclature and classification of human biological targets, including targets of current and future prescription medicines. Works to facilitate interface between discovery of new sequences from Human Genome Project and designation of derived entities as functional biological targets and potential drug targets. Developes database which provides access to data on all known biological targets.
Proper citation: NC-IUPHAR (RRID:SCR_006901) Copy
http://www.nationalstemcellbank.org/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 17, 2011. The US government contract funding the National Stem Cell Bank (NSCB) ended on February 28, 2010.
A repository for the pluripotent stem cells lines listed on the NIH Human Pluripotent Stem Cell Registry. These cells were derived prior to August 2001 using excess IVF embryos and were eligible for use in federally funded research under previous presidential policy. The eligibility of these lines will not be known until the NIH issues final stem cell guidelines in July 2009. The goal of the NSCB is to grow, characterize and distribute the cell lines listed on the registry, and to provide comprehensive technical support to stem cell researchers around the world.
Starting February 2, 2010, these materials can be ordered from the Wisconsin International Stem Cell Bank (the WISC Bank) operated by WiCell Research Institute, for delivery after February 28, 2010.
Proper citation: National Stem Cell Bank (RRID:SCR_004725) Copy
European website providing information about orphan drugs and rare diseases. It contains content both for physicians and for patients. Reference portal for rare diseases and orphan drugs to help improve diagnosis, care and treatment of patients with rare diseases.
Proper citation: Orphanet (RRID:SCR_006628) Copy
https://sfari.org/resources/simons-simplex-collection
Repository of genetic samples from approximately 3,000 families, each of which has one child affected with an Autism Spectrum Disorder (ASD) and parents unaffected with ASD. A central database characterizing all of the study subjects is available to any qualified researcher and biospecimens are freely available to SFARI grant holders, and to other researchers on a modest fee-for-use basis. Each genetic sample will have an associated collection of data that provides a precise characterization of the individual (phenotype). Rigorous phenotyping will maximize the value of the resource for a wide variety of future research projects into the causes and mechanisms of autism. The Simons Simplex Collection is operated by SFARI in collaboration with twelve university-affiliated research clinics.
Proper citation: Simons Simplex Collection (RRID:SCR_004644) Copy
Center for investigators studying human health and disease, offering the opportunity to assess the causes of disease, and new treatment methods in nonhuman primate models that closely recapitulate humans. Its mission is to provide interdisciplinary programs in biomedical research on significant human health-related problems in which nonhuman primates are the models of choice.
Proper citation: California National Primate Research Center (RRID:SCR_006426) Copy
The CEI Science & Technology Network (S&TN), launched at the beginning of 2004, is composed of sevenTrieste-based research centres and their partners in the CEI region. With the aim to strengthen scientific and technological cooperation, the S&TN provides financial support for the organization of seminars, conferences, workshops and training courses. Young scientists from CEI countries, especially non-EU member States, are offered the opportunity to attend such activities and carry out scientific research on various topics in one of the seven Lead Institutions (LIs). The area of cooperation of each Lead Institution is separately defined in a three-year Protocol complemented by an annual Work Programme. During 2004-2009, the Network''s Lead Institutions implemented a number of activities, some of which in partnership with other institutions from CEI countries. This cooperation started up the Secondary Network whose further enhancement will be the main challenge in the future years. The CEI Research Fellowship Programme The CEI Research Fellowship Programme was established in 2005 to enable mobility across the CEI region by giving selected scientists the possibility of carrying out research in one of the Network''s Lead Institutions. In the time-frame 2005 - 2009, the request for fellowships has constantly increased and witnessed the effectiveness of the Programme. Taking this into account, in 2008 the CEI-ES started to explore EU funding opportunities in order to develop its Research Fellowship Programme. A joint proposal named CERES (CEI Research Fellowship Programme) was submitted to the European Commission under the Seventh Framework Programme for Research and Technological Development (FP7). CERES was approved and is currently under implementation. EU Funding opportunities for the CEI Science & Technology Network Following the successful experience of CERES, the CEI-ES, along with the Network''s Lead Institutions, will continue to look into funding opportunities offered by the EU with the ultimate aim to support mobility of researchers across the CEI area and promote significant progress in the S&T sector.
Proper citation: CEI Science and Technology Network (RRID:SCR_005338) Copy
A comprehensive analysis and visualization software package for gene expression experiments that provides: a number of clustering and analysis techniques; integrated gene expression and analysis result visualizations, integration with the Gene Expression Omnibus; and an optional data sharing architecture. GO is used to assign functional enrichment scores to clusters, using a combination of specially developed techniques and general statistical methods. These results can be explored using the in built ontology browsing tool or through the generated web pages. SeqExpress also supports numerous data transformation, projection, visualization, file export/import, searching, integration (with R), and clustering options.
Proper citation: SeqExpress (RRID:SCR_007075) Copy
Software package that provides the ability to do a number of standard semantic similarity methods and includes novel methods for combining these with dynamic selection of anonymous grouping classes. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible
Proper citation: OwlSim (RRID:SCR_006819) Copy
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