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https://www.med.upenn.edu/idom/drc/cores/cellbio.html

Provides support including experimental design, islet isolation, and performance of and/or training in range of assays for physiological, metabolic, and morphometric assessment of pancreatic islets as wells as many other tissues and cell types. Offers islet isolation and culture, free intracellular calcium ion measurements, quantitative oxygen consumption of pancreatic islets, electrode based closed cell respirometry, and access to Agilent�s� Seahorse Extracellular Flux Analyzer XFe96.

Proper citation: University of Pennsylvania Perelman School of Medicine Pancreatic Islet Cell Biology Core Facility (RRID:SCR_022411) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cvi/mouse-cardiovascular-phenotyping-core.html

Core provides services to assess cardiovascular function in mouse models and to provide validated surgical models of heart and vascular disease in mice to assess genetic or therapeutic interventions. Works with investigators to design and implement study along with any associated grant applications, animal protocol submissions and manuscript preparation. While central focus of facility is cardiovascular research, techniques employed are often useful to investigators in other fields. Helps to assess your needs and provide necessary technical training and scientific assistance in animal protocol preparation. Core runs on a fee for service model.�Accordingly, investigators will be responsible for costs incurred for their projects and prior animal protocol approval by Penn IACUC., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of Pennsylvania Perelman School of Medicine Mouse Cardiovascular Phenotyping Core Facility (RRID:SCR_022419) Copy   

•   Source: SciCrunch Registry

https://www.janelia.org/support-team/light-microscopy

Facility is open to Janelia scientists. Houses microscopes and multiple workstations dedicated to image processing.

Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Light Microscopy Core Facility (RRID:SCR_022103) Copy   

•   Source: SciCrunch Registry

https://cds.vanderbilt.edu

Shared Resource that offers bioinformatics and informatics services for basic research and clinical projects.

Proper citation: Vanderbilt University Creative Data Solutions Core Facility (RRID:SCR_022366) Copy   

•   Source: SciCrunch Registry

http://researchservices.pitt.edu/facilities/microscopy-and-imaging-suite

Facility equipped with instruments for optical and electron microscopy, and Flow Cytometry.Offers experimental design, equipment training, staff operated image acquisition, and image analysis. All users must be trained by Facility staff to access the equipment.

Proper citation: University of Pittsburgh Microscopy and Imaging Suite Core Facility (RRID:SCR_022084) Copy   

•   Source: SciCrunch Registry

https://www.umass.edu/ials/biophysical-characterization

Provides expertise and access to instruments for study of structures and interactions of biological macromolecules such as proteins, nucleic acids, lipids, and complexes. Facility supports both discovery based research and assay development for translational applications. Offers to use equipment independently or with the help of faculty who have expertise in each method.

Proper citation: University of Massachusetts Amherst Biophysical Characterization Core Facility (RRID:SCR_022357) Copy   

•   Source: SciCrunch Registry

https://www.mines.edu/shared-facilities/cores/#XPS

Core to measure material surface compositions by measuring intensity of photoelectrons emitted as function of incident X-ray energy. Spectra features are used to identify surface species present and calculate fraction of surface occupied by each.Rocky Mountain E-XPS extends these traditional capabilities by enabling measurements in range of environmental conditions.

Proper citation: Colorado School of Mines Shared Instrumentation Facility Rocky Mountain Environmental X-Ray Photoelectron Spectroscopy Core Facility (RRID:SCR_022050) Copy   

•   Source: SciCrunch Registry

https://qb3.berkeley.edu/facility/genomics/

Partnership between Vincent J. Coates Genomics Sequencing Laboratory,Functional Genomics Laboratory, and Computational Genomics Resource Laboratory. Offers consultation on experimental design and data analysis, full suite of technical services related to high throughput sequencing and genomics experiments, and access to high performance computational infrastructure.

Proper citation: University of California at Berkeley QB3 Genomics Core Facility (RRID:SCR_022170) Copy   

•   Source: SciCrunch Registry

http://www.mri.cnrs.fr

Cell imaging facility of Montpellier area, France.Offers access to cutting edge instruments for optical and electron microscopy, flow cytometry, and X-ray micro tomography. Instruments are housed in seven sites that mirror distribution of Life Science research campuses of the region. Mission is to support research by offering imaging instruments and image analysis solutions.

Proper citation: Montpellier Imagining Resources MRI Core Facility (RRID:SCR_022290) Copy   

•   Source: SciCrunch Registry

https://www.mines.edu/shared-facilities/cores/#MS

Liquid Chromatography Mass Spectrometry is analytical technique for determining ion mass-to-charge ratio by partitioning particles within liquid and measuring time it takes for each particle to travel through selected mobile phase. Ultimately this helps in determining contents of liquid sample and can be used to analyze biochemical, organic and inorganic compounds.

Proper citation: Colorado School of Mines Shared Instrumentation Facility Liquid Chromotography Mass Spectrometry Core Facility (RRID:SCR_022052) Copy   

•   Source: SciCrunch Registry

https://www.mines.edu/shared-facilities/project/iontof-tof-sims-v/

Core used to obtain elemental, isotopic, and molecular information from surface of solid materials and compacted powders.

Proper citation: Colorado School of Mines Shared Instrumentation Facility Time of Flight Secondary Ion Mass Spectrometry Core Facility (RRID:SCR_022049) Copy   

•   Source: SciCrunch Registry

https://www.pedsresearch.org/research/cores/flow-cytometry-core/overview/

Core provides cytometry services for analysis and sorting of cells as well as expert consultation for experimental design and planning. Offers access to several analytical flow cytometers as well as high speed cell sorting. Training and technical expertise is available.

Proper citation: Emory University and Pediatric Winship Flow Cytometry Core Facility (RRID:SCR_022324) Copy   

•   Source: SciCrunch Registry

https://www.mines.edu/shared-facilities/cores/#EM

Facility provides SEM, FIB, TEM, scanning probe, and optical techniques for analyzing materials.

Proper citation: Colorado School of Mines Shared Instrumentation Facility Electron and Scanning Probe Microscopy Core Facility (RRID:SCR_022048) Copy   

•   Source: SciCrunch Registry

http://www.facs.au.dk

Facility is equipped with cell sorters, analyzers, ImageStream and full spectrum flow cytometer. Staff provides training and maintenance.

Proper citation: Aarhus University Fluorescence Activated Cell Sorting Core Facility (RRID:SCR_022323) Copy   

•   Source: SciCrunch Registry

https://github.com/KaetzelLab

Operant Box code

Proper citation: pyOS-5 (RRID:SCR_022336) Copy   

•   Source: SciCrunch Registry

https://vpr.tamu.edu/core_facility/high-throughput-research-and-screening-center/

Core provides industry standard high throughput screening and automated microscopy capabilities to scientists performing drug discovery research. Provides access to automated infrastructure to support phenotypic and biochemical targets. Provides ready access to collections of current FDA approved drugs and clinical candidates exhibiting drug like qualities of acceptable solubility, desirable ADME/toxicology properties and adequate bioavailability. Has collections of mechanistically annotated informer sets that are pathway specific modulators for studying mechanism of action or target identification, collections of natural products and diverse sets of small molecules that can be interrogated for new target discovery. Each project is individually evaluated and team of scientists from CDDP is created to fit specific needs of project from assay design and development through primary, secondary and orthogonal screening.

Proper citation: Texas A and M University Institute of Biosciences and Technology High Throughput Research and Screening Center Combinatorial Drug Discovery Core Facility (RRID:SCR_022214) Copy   

•   Source: SciCrunch Registry

http://pimp.starflr.info/

A database ofhuman disease-related mutated proteins identified by mass-spectrometry (MS). For achieving this goal, we collected human mutated sequences known to be related to diseases till now. After surveying mutated sequence sources: PMD, OMIM, SwissProt polymorphism, HGMD, etc, we found that currently HGMD contains the largest human gene mutation information. However, because, for academic users, HGMD does not provide with whole data download service, we decided to systematically extract and curate mutation information from PMD, OMIM, SwissProt, MSIPI database to form SysPIMP and provide it free for academic users.

Proper citation: Systematic Platform for Identifying Mutated Proteins (SysPIMP) (RRID:SCR_007954) Copy   

•   Source: SciCrunch Registry

http://systers.molgen.mpg.de/

SYSTERS is a database of protein sequences grouped into homologous families and superfamilies. The SYSTERS project aims to provide a meaningful partitioning of the whole protein sequence space by a fully automatic procedure. A refined two-step algorithm assigns each protein to a family and a superfamily. The sequence data underlying SYSTERS release 4 now comprise several protein sequence databases derived from completely sequenced genomes (ENSEMBL, TAIR, SGD and GeneDB), in addition to the comprehensive Swiss-Prot/TrEMBL databases. To augment the automatically derived results, information from external databases like Pfam and Gene Ontology are added to the web server. Furthermore, users can retrieve pre-processed analyses of families like multiple alignments and phylogenetic trees. New query options comprise a batch retrieval tool for functional inference about families based on automatic keyword extraction from sequence annotations. A new access point, PhyloMatrix, allows the retrieval of phylogenetic profiles of SYSTERS families across organisms with completely sequenced genomes. Gene, Human, Vertebrate, Genome, Human ORFs

Proper citation: SYSTERS (RRID:SCR_007955) Copy   

•   Source: SciCrunch Registry

http://supfam.org/SUPERFAMILY/

SUPERFAMILY is a database of structural and functional protein annotations for all completely sequenced organisms. The SUPERFAMILY annotation is based on a collection of hidden Markov models, which represent structural protein domains at the SCOP superfamily level. A superfamily groups together domains which have an evolutionary relationship. The annotation is produced by scanning protein sequences from over 1,700 completely sequenced genomes against the hidden Markov models.

Proper citation: SUPERFAMILY (RRID:SCR_007952) Copy   

•   Source: SciCrunch Registry

http://stitch.embl.de

Database to explore known and predicted interactions of chemicals and proteins. It integrates information about interactions from metabolic pathways, crystal structures, binding experiments and drug-target relationships. Inferred information from phenotypic effects, text mining and chemical structure similarity is used to predict relations between chemicals. STITCH further allows exploring the network of chemical relations, also in the context of associated binding proteins. Each proposed interaction can be traced back to the original data sources. The database contains interaction information for over 68,000 different chemicals, including 2200 drugs, and connects them to 1.5 million genes across 373 genomes and their interactions contained in the STRING database.

Proper citation: Search Tool for Interactions of Chemicals (RRID:SCR_007947) Copy   

•   Source: SciCrunch Registry