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http://www.ontariotumourbank.ca/

The Ontario Tumour Bank is a province-wide biorepository and data bank focused on collection of tumor-related human biospecimens. It provides academic and industry cancer researchers with a diverse selection of high quality tumor-related specimens and data obtained directly by dedicated tumour bank staff, who follow a stringent set of procedures and ethical guidelines. The biospecimens and clinical data are an important resource for scientists engaged in translational research who are developing better diagnostic tools and new drug therapies. Researchers depend on the Ontario Tumour Bank to provide research biospecimens of high quality, diversity, and integrity. Operating at state-of-the-art hospitals and cancer centers across Ontario, the Ontario Tumour Bank coordinates the collection, storage, analysis, annotation, and distribution of tumor and peripheral blood samples. Working in collaboration with local pathologists, medical oncologists, surgeons and other hospital personnel, specially trained staff obtain patient consent, collect tissues and assemble comprehensive clinical information about each donor and the corresponding samples.

Proper citation: Ontario Tumour Bank (RRID:SCR_004732) Copy   

•   Source: SciCrunch Registry

http://www.yeastgenome.org/

A curated database that provides comprehensive integrated biological information for Saccharomyces cerevisiae along with search and analysis tools to explore these data. SGD allows researchers to discover functional relationships between sequence and gene products in fungi and higher organisms. The SGD also maintains the S. cerevisiae Gene Name Registry, a complete list of all gene names used in S. cerevisiae which includes a set of general guidelines to gene naming. Protein Page provides basic protein information calculated from the predicted sequence and contains links to a variety of secondary structure and tertiary structure resources. Yeast Biochemical Pathways allows users to view and search for biochemical reactions and pathways that occur in S. cerevisiae as well as map expression data onto the biochemical pathways. Literature citations are provided where available.

Proper citation: SGD (RRID:SCR_004694) Copy   

•   Source: SciCrunch Registry

http://www.biobank-gso.org/apex/f?p=200:1:2527679222961463

The Virtual Tumour Bank of the Canceropole Grand Sud-Ouest''s mission is to federate the cancer research of four French regions: Aquitaine, Languedoc-Roussillon, Limousin and Midi-Pyrenees. This site allows access to an inventory of the specimens stored in the tumor banks of the Greater South-West region, within the laboratories of Pathology of the University Hospital Centers and Cancer Centers of Bordeaux, Limoges, Montpellier, Nimes and Toulouse. You may search by disease or multiple criteria. These specimens are removed from patients primarily to confirm and accurately characterize their cancer diagnosis, and are therefore stored by the tumor bank for diagnostic and/or therapeutic purposes. These samples can be re-qualified for scientific research pending that a number of conditions are met, including the absence of refusal from the person (in compliance with French regulations). So far, the tumor bank is a major tool for cancer treatment and research. This inventory is a further evidence of the coordination effort between the eight concerned tumor banks that have been mobilized at the service of patients and research within the framework of the Canceropole Grand Sud-Ouest programs. These biological resources are made available to research groups that conduct basic or translational programs in the field of oncology. They will not be made available for projects in fields other than oncology.

Proper citation: Southwest France Tumour Bank (RRID:SCR_004574) Copy   

•   Source: SciCrunch Registry

http://www.ebi.ac.uk/thornton-srv/databases/profunc/index.html

The ProFunc server had been developed to help identify the likely biochemical function of a protein from its three-dimensional structure. It uses both sequence- and structure-based methods including fold matching, residue conservation, surface cleft analysis, and functional 3D templates, to identify both the protein''''s likely active site and possible homologues in the PDB. Often, where one method fails to provide any functional insight another may be more helpful. You can submit your own structure, analyze an existing PDB entry, or retrieve the results of a previously submitted run. The files are usually stored for about 6 months before being deleted. However, they are stored on a partition that is not backed up; so, in principle, they could disappear at any time.

Proper citation: ProFunc (RRID:SCR_004450) Copy   

•   Source: SciCrunch Registry

http://zfin.org/action/antibody/search

The ZFIN Antibody Database is a database of zebrafish gene expression antibodies.

Proper citation: ZFIN Antibody Database (RRID:SCR_004729) Copy   

•   Source: SciCrunch Registry

http://www.cornellsurgery.org/pro/services/burn-surgery/skin-bank.html

Established nearly 30 years ago, the New York Firefighters Skin Bank is the only comprehensive skin bank in New York State, providing allograft skin grafts to patients throughout the region. Allograft skin grafts enable burn victims to fight infection, maintain their fluids and body heat, and control pain. The Skin Bank also provides cryopreservation services so that patients can bank their own skin for future autologous transplantation.

Proper citation: New York Firefighters Skin Bank (RRID:SCR_004604) Copy   

•   Source: SciCrunch Registry

http://www.gsds.org/Home%20Page

Golden State Donor Services (GSDS) is the nonprofit, federally designated transplant donor network serving two and a half million people in the greater Sacramento area. We are committed to saving and improving lives by connecting one life to another through donation and transplantation. We support potential donor families in their time of loss, provide care for them through the donation process and coordinate the recovery of organs and tissues for transplant. We also provide after-care support to donor families while at the same time working to inspire universal acceptance of donation to ensure every person in need receives the ����??Gift of Life.����?? GSDS'' designated service area includes 11 counties in Northern California, (Amador, Calaveras, Colusa, El Dorado, Nevada, Placer, Sacramento, Sierra, Sutter, Yolo, and Yuba), as well as the communities of Santa Rosa and Reno. Currently GSDS has agreements with 30 hospitals. In Golden State Donor Services'' area, more than 1000 people now wait for an organ transplant, (heart, liver, lungs, kidneys, intestine or pancreas).

Proper citation: GSDS - Golden State Donor Services (RRID:SCR_004605) Copy   

•   Source: SciCrunch Registry

http://pfam.xfam.org/

A database of protein families, each represented by multiple sequence alignments and hidden Markov models (HMMs). Users can analyze protein sequences for Pfam matches, view Pfam family annotation and alignments, see groups of related families, look at the domain organization of a protein sequence, find the domains on a PDB structure, and query Pfam by keywords. There are two components to Pfam: Pfam-A and Pfam-B. Pfam-A entries are high quality, manually curated families that may automatically generate a supplement using the ADDA database. These automatically generated entries are called Pfam-B. Although of lower quality, Pfam-B families can be useful for identifying functionally conserved regions when no Pfam-A entries are found. Pfam also generates higher-level groupings of related families, known as clans (collections of Pfam-A entries which are related by similarity of sequence, structure or profile-HMM).

Proper citation: Pfam (RRID:SCR_004726) Copy   

•   Source: SciCrunch Registry

http://www.mts-stl.org/

For 35 years, Mid-America Transplant Services (MTS) has served as the regional organ and tissue procurement organization for eastern Missouri, southern Illinois, and northeast Arkansas, serving 4.3 million people in 84 counties. From our founding goal to assist in the coordination of kidney donations, we have grown to become a multi-faceted organization dedicated to saving lives and enhancing the quality of all donated organs and tissues currently available for transplant. MTS''s primary service offering is to facilitate and coordinate the organ and tissue donation process. With a mission to save lives through excellence in organ and tissue donation, we have been at the forefront of enhancing the quality of organs and tissue for transplant. Throughout our history, we have relentlessly pursued our core values of compassion, quality, teamwork, and honesty to create a positive donation experience for Donor Families, which is at the heart of what matters most to MTS. Located in Saint Louis, Missouri, MTS is one of 58 federally designated organizations of its kind in the United States. Incorporated in the State of Missouri, MTS is a private, not-for-profit 501(c)(3). To fulfill our mission, we work closely with the four transplant centers and over 110 donor hospitals located within our service area.

Proper citation: Mid-America Transplant Services (RRID:SCR_004400) Copy   

•   Source: SciCrunch Registry

http://s213659397.onlinehome.us/lifetek.org/lifetek_Welcome.html

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. LifeTek is a full service International Tissue Bank, with recovery and processing partners in the United States, Spain and Mexico. Our goal is to provide safe, quality allograft implants, therefore serving donor families, physicians and recipients. Following regulations established by state and federal agencies, including the United States Food and Drug Administration, specific steps are taken to ensure donor suitability, including serologic testing performed by CLIA certified laboratories. LifeTek aseptically process tissues in Class 100 Cleanrooms, significantly reducing the risk of airborne contaminants. Equipment and reagents used are sterilized in steam autoclaves. Grafts are further processed and sterilized using Clearant Technology. LifeTek allografts are provided either freeze-dried or frozen. Freeze-dried allografts are stored at ambient temperatures, while frozen allografts are stored at -40 degrees C or colder. Freeze-dried allografts are provided with a maximum of two years expiration, frozen allografts are provided with a maximum of five years expiration.

Proper citation: LifeTek OrthoBiologics (RRID:SCR_004488) Copy   

•   Source: SciCrunch Registry

http://www.ncbi.nlm.nih.gov/mapview/map_search.cgi?taxid=7165

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. A database for the Anopheles gambiae str. PEST genome that was sequenced using a whole genome shotgun approach. The database aims to contribute to the understanding of mosquito genome structure and organization and will assist the development of malaria control strategies and improved anti-malarial drugs and vaccines. Sequences were generated and assembled into contigs for submission to GenBank.

Proper citation: Anopheles gambiae (African malaria mosquito) genome view (RRID:SCR_004402) Copy   

•   Source: SciCrunch Registry

http://www.uniprot.org/taxonomy/

NEWT is the taxonomy database maintained by the UniProt group. It integrates taxonomy data compiled in the NCBI database and data specific to the UniProt Knowledgebase. Browse by hierarchy, List all, or Complete proteomes. Organisms are classified in a hierarchical tree structure. Our taxonomy database contains every node (taxon) of the tree. UniProtKB taxonomy data is manually curated: next to manually verified organism names, we provide a selection of external links, organism strains and viral host information. Species with protein sequences stored in the UniProt Knowledgebase are named according to UniProt nomenclature. We endeavour to maintain a list of manually curated species names for which protein sequence data is available. In particular, we have adopted a systematic convention for naming viral and bacterial strains and isolates. Links to external sites are chosen by the UniProt taxonomy team and show pictures and various scientific data of interest (taxonomy, biology, physiology,...).

Proper citation: NEWT (RRID:SCR_004477) Copy   

•   Source: SciCrunch Registry

http://pluto3.nci.nih.gov/tissue/default.cfm

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. The Specimen Resource Locator is a database to help researchers locate human specimens (tissue, serum, DNA/RNA, other specimens) for cancer research. It includes tissue banks and tissue procurement systems with access to normal, benign, precancerous and cancerous human tissue from a variety of organs. Researchers specify the types of specimens, number of cases, preservation methods and associated data they require. The Locator will then search the database and return a list of tissue resources most likely to meet their requirements. When no match is obtained, the researcher is referred to the NCI Tissue Expediter ([email protected]). The Tissue expediter is a scientist who can help researchers identify appropriate resources and/or appropriate collaborators.

Proper citation: NCI Specimen Resource Locator (RRID:SCR_004754) Copy   

•   Source: SciCrunch Registry

https://reich.hms.harvard.edu/software

Software application that finds skews in ancestry that are potentially associated with disease genes in recently mixed populations like African Americans. It can be downloaded for either UNIX or Linux.

Proper citation: Ancestrymap (RRID:SCR_004353) Copy   

•   Source: SciCrunch Registry

http://www.bccrc.ca/dept/ttr

A provincial biobank resource to support translational cancer research at the BC Cancer Agency, across Canada and internationally. This biobank collects biospecimens (tissues and blood), and clinical information and processes these to create anonymous cases that can be studied by cancer researchers to understand how cancer develops, how it grows, how it spreads, and how it responds to treatment. These tissues and data are obtained from patients who undergo surgery to treat a tumor and who have generously provided their consent for the TTR to collect tissues that are unused after diagnosis has been completed. The TTR is a provincial program that currently comprises a core biobank at the Vancouver Island Center, Victoria, that offers participation in the program to patients in Victoria and Nanaimo. The TTR works with other banks and expert translational research groups in BC, to create expanded capacity for collection and opportunities for research access to tissue resources. The TTR operates under the management and oversight of the director, a scientific advisory board, and the UBC BCCA Research Ethics Board. The TTR operates within organizational policies and a commitment to protection of donor privacy that is embodied in all standard operating procedures and aspects of the repository. The TTR is also a founding member and contributor to the development of provincial (BC BioLibrary) and national (CTRNet) initiatives to promote biobanking.

Proper citation: British Columbia Tumour Tissue Repository (RRID:SCR_004597) Copy   

•   Source: SciCrunch Registry

http://www.nsabp.pitt.edu/NSABP_Pathology.asp

The NSABP (National Surgical Adjuvant Breast and Bowel Project) Tissue Bank is the central repository of tissue samples (stained and unstained slides, tissue blocks, and frozen tissue specimens) collected from clinical trials conducted by the NSABP. The main scientific aim of the NSABP Division of Pathology is to develop clinical context-specific prognostic markers and predictive markers that predict response to or benefit from specific therapeutic modality. To achieve this aim, the laboratory collects the tumor and adjacent normal tissues from cancer patients enrolled into the NSABP trials through its membership institutions, and maintain these valuable materials with clinical follow-up information and distribute them to qualified approved investigators. Currently, specimens from more than 90,000 cases of breast and colon cancer are stored and maintained at the bank. Paraffin embedded tumor specimens are available from NSABP trials. We currently do not bank frozen tissues. All blocks are from patients enrolled in prospective NSABP treatment protocols and complete clinical follow up information as well as demographic information is available. Depending on the project, unstained tissue sections of 4-micrometer thickness, tissue microarrays, or stained slides are provided to the investigators in a blinded study format. Any investigators with novel projects that conform to the research goals of NSABP may apply for the tissue. Please refer to the NSABP Tissue Bank Policy to determine if your project conforms to these goals. Priority is given to NSABP membership institutions who regularly submit tissue blocks.

Proper citation: National Surgical Adjuvant Breast and Bowel Project Tissue Bank (RRID:SCR_004506) Copy   

•   Source: SciCrunch Registry

https://www.beaumonthospitals.com/biobank

BioBank is a new Beaumont research center that is focused on developing innovative methods for early detection of disease and personalized treatment plans through leading edge analysis techniques and state of the art technologies. Biomarkers from tissue, blood or fluids, are used to develop the next generation of care management, taking it from bench to bedside. Beaumont BioBank will work to: * collect high-quality biological specimens from any specialty at Beaumont * store, analyze and record specimens in an efficient, organized and accessible manner using leading-edge technologies * connect specialties and specialists with each other across traditional hospital or laboratory departments to provide a multidisciplinary research structure * facilitate translational research that links molecular laboratory techniques that enable us to apply biomarker discoveries to clinical outcome studies in a speedy and direct manner

Proper citation: Beaumont Hospitals Biobank (RRID:SCR_004666) Copy   

•   Source: SciCrunch Registry

http://www.lifelinktb.org/

Established in 1985, LifeLink Tissue Bank is a not-for-profit organization dedicated to serving patients in need of transplantation therapy. It is one of five divisions of the LifeLink Foundation and the largest not-for-profit tissue bank in the Southeast and one of the largest in the United States. LifeLink Tissue Bank is inspected and accredited by The American Association of Tissue Banks (AATB). Our goal is to provide the safest, most clinically effective allografts while remaining cognizant of the rising cost of medical care. Donors and their families are the core of our organization. We treat them with respect, show them compassion, and offer them comfort in knowing that their confidentiality is protected and their gifts optimally utilized. Our allografts are utilized by surgeons and hospitals that trust LifeLink to provide them with safe and clinically effective allografts. Every effort is made to ensure that our allografts are placed back in the hospitals of the communities that we serve with organ and tissue recovery services.

Proper citation: LifeLink Tissue Bank (RRID:SCR_004546) Copy   

•   Source: SciCrunch Registry

http://selectome.unil.ch/

Database of positive selection based on a rigorous branch-site specific likelihood test. Positive selection is detected using CODEML on all branches of animal gene trees.

Proper citation: Selectome: a Database of Positive Selection (RRID:SCR_004542) Copy   

•   Source: SciCrunch Registry

http://www.ucl.ac.uk/cancer/medical-genomics/clinepi

Aims to carry out an integrated (epi)genomic analysis of the NET BioBank established at the Royal Free and UCL Hospitals to identify new biomarkers for translation into diagnostics and therapeutics. The Neuroendocrine Tumour (NET) Unit at the Royal Free Campus of UCL Hospitals has an international reputation for the management of neuroendocrine tumor patients. It currently receives around 10 new referrals per month and has an active patient cohort of over 800 patients. We receive referrals from across the UK as well as from abroad. It is the designated center for NETs within the North London Cancer Network. In order to improve both treatment and outcome in Neuroendocrine Tumors (NETs), better understanding of their biology and the biological pathways involved is imperative (reviewed in (Modlin et al., 2008)). Currently, the use of targeted treatments is limited and management challenging due to the lack of knowledge of the molecular pathogenesis and mechanistic regulation of these tumors (Barakat et al., 2004). Due to the rarity of NETs and difficulty in obtaining fresh tissue and archival samples, very little is known about the (epi)genetic and germline mutations associated with neuroendocrine tumors ����?? which encompass a clinically and genetically heterogeneous group. To date, studies have been small and under-powered. Clinical trials have included small patient numbers and are often non-randomized phase II trials comparing a new therapy against a non-standardized first line treatment. Initially we will undertake genome-wide methylation analysis on our entire cohort of neuroendocrine tumors in order to determine the methylation profiles of differing NET types. This will improve diagnostic accuracy and potentially identify new therapeutic targets and biomarkers. These studies will be performed on high-throughput analysis platforms based on micoarrays and next-generation sequencing. In parallel, we will analyze the mRNA expression profiles of these tumors to enable integrated (epi)genomic analysis of these intriguing tumors.

Proper citation: Neuroendocrine Tumors Biobank (RRID:SCR_004380) Copy   

•   Source: SciCrunch Registry