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https://www.med.upenn.edu/immunehealth/

Core provides infrastructure and technical support for scaling clinical immune profiling of large scale clinical cohorts. Provides biospecimen processing, sample storage, high dimensional immune assays, computational analysis, and project management. Services are only available to investigators and teams whose cohorts have been approved by the Immune Health leadership.

Proper citation: University of Pennsylvania Institute for Immunology and Immune Health I3H Core Facility (RRID:SCR_024574) Copy   

•   Source: SciCrunch Registry

https://www.huck.psu.edu/core-facilities/cryo-electron-microscopy-facility

Cryo-Electron Microscopy Facility houses FEI Titan Krios microscope that offers data collection for life sciences while incorporating materials science applications. Used for creating super high definition 3D images of atoms and molecules. Facility allows for fully automated atomic resolution single particle and high contrast tomography tilt-series data collection. Additional microscopy components permit a full range of materials science applications, including EELS, STEM, and DPC. Facility also houses ThermoFisher Arctica G2.

Proper citation: Pennsylvania State University Huck Institutes Cryo-Electron Microscopy Core Facility (RRID:SCR_024456) Copy   

•   Source: SciCrunch Registry

https://research.pasteur.fr/en/team/human-disease-models-core-facility/

Core Facility produces mice harboring human immune system and provides expertise for possible applications of this model. HIS mice engrafted with human Hematopoietic stem cells are advantageous in vivo models for long term studies in field of human immune cells biology, immune oncology and infectious disease. They constitute small animal model in which to analyze potency and safety of small animal model modulating immune system.

Proper citation: Pasteur Institute Human Disease Models Core Facility (RRID:SCR_023881) Copy   

•   Source: SciCrunch Registry

https://tnprc.tulane.edu/infectious-disease-aerobiology-core

Core focuses on infectious disease aerobiology. Core facilitates biomedical research efforts that require unique demands of aerosol and aerobiology in their respective performance.

Proper citation: Tulane University TNBRC Infectious Disease Aerobiology Core Facility (RRID:SCR_024608) Copy   

•   Source: SciCrunch Registry

https://tnprc.tulane.edu/clinical-pathology-core

Clinical Pathology Core performs clinical diagnostic testing for all research and colony animals. This includes complete blood counts, routine chemistry panels, and microbial culture workups. The lab is equipped with Sysmex XN1000v veterinary hematology analyzer, Beckman AU480 chemistry analyzer, and Matrix assisted laser desorption ionization time of flight MALDI-TOF instrument for microbe identification. CPC is staff with American Society of Clinical Pathologist certified licensed Medical Technologists.

Proper citation: Tulane University TNBRC Clinical Pathology Core Facility (RRID:SCR_024609) Copy   

•   Source: SciCrunch Registry

https://imaging.au.dk

Core Facility offers equipment for wide range of light microscopy applications as well as access to advanced bioimaging software. Specialized staff offers personal training and assistance.

Proper citation: Aarhus University Bioimaging Core Facility (RRID:SCR_023876) Copy   

•   Source: SciCrunch Registry

https://github.com/WorkflowConversion/CTDopts

Software gives your command-line tools a CTD-compatible interface. Module for enabling tools with CTD reading/writing, argument parsing, validating and manipulating capabilities.

Proper citation: CTDopts (RRID:SCR_023997) Copy   

•   Source: SciCrunch Registry

https://www.beatson.gla.ac.uk/advanced-technologies/bair.html

Core to uncover and interrogate important molecular pathways in cancer. Offers training scientists in all stages of modern microscopical research from advice on experimental design and sample preparation, basic and advanced microscope operation and data acquisition through to quantitative image analysis and interpretation.

Proper citation: Beatson Institute for Cancer Research United Kingdom Beatson Advanced Imaging Resource Core Facility (RRID:SCR_023875) Copy   

•   Source: SciCrunch Registry

https://github.com/Optophys-Lab/FreiBox/tree/main/Commutator_FreiBox2022

Affordable commutator that is equipped with novel sensing system that improves online tracking of cable rotations without impairing the 1-photon calcium imaging via Miniscope. Commutator to allow freely moving behaviors while recording neural activity from platforms such as Miniscope V4 and OpenEphys. Used to perform calcium imaging.

Proper citation: commutator (RRID:SCR_023919) Copy   

•   Source: SciCrunch Registry

https://github.com/Optophys-Lab/FreiBox

Versatile open source behavioral system for investigating neuronal correlates of behavioral flexibility via 1-Photon Imaging in freely moving mice. Behavioral testing platform consists of FreiBox, novel low-cost Arduino behavioral setup, controlled by custom Python interface and integrates new licking sensor (strain gauge lickometer) for controlling spatial licking behavioral tasks.

Proper citation: Freibox (RRID:SCR_023918) Copy   

•   Source: SciCrunch Registry

https://tnprc.tulane.edu/anatomic-pathology-core

Anatomic Pathology Core is responsible for post-mortem examinations, tissue collection and distribution, fixation, processing, slide preparation, routine and special staining, and diagnostic gross and histologic pathology services. Processes and interprets biopsy specimens for both research and diagnostic purposes and provides tissue trimming, paraffin processing, sectioning, and routine and special staining for clinical and research staff and faculty. APC works closely with clinical veterinarians, and through diagnostic pathology on biopsies and necropsies, plays major role in monitoring and maintaining health of animals in breeding colonies.

Proper citation: Tulane University TNBRC Anatomic Pathology Core Facility (RRID:SCR_024606) Copy   

•   Source: SciCrunch Registry

https://www.huck.psu.edu/core-facilities/proteomics-and-mass-spectrometry-core-facility

Facility offers highly sensitive and accurate mass spectrometry analysis, including identification and quantitation of proteins by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS-MS) or by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-TOF-MS).

Proper citation: Pennsylvania State University Huck Institutes Proteomics and Mass Spectrometry Core Facility (RRID:SCR_024462) Copy   

•   Source: SciCrunch Registry

https://github.com/nickpetersen93/LIQ_HD

Arduino code, 3D print design files, and tutorial video on how to build LIQ HD system. Open source tool for recording undisturbed two-bottle drinking behavior in home cage environment. All designs and software are open source to allow other researchers to build on the system and adapt LIQ HD to their animal home cages.

Proper citation: Lick Instance Quantifier Home cage Device (RRID:SCR_023802) Copy   

•   Source: SciCrunch Registry

https://www.huck.psu.edu/core-facilities/microscopy-facility

Microscopy facility specializes in areas of optical microscopy, electron microscopy, and histology. Facility is equipped with confocal microscopes, research fluorescence microscopes, and transmission and scanning electron microscopes. Research staff engage in experimentation, training, project collaboration, and consultation.

Proper citation: Pennsylvania State University Huck Institutes Microscopy Core Facility (RRID:SCR_024457) Copy   

•   Source: SciCrunch Registry

https://tnbrc.tulane.edu/cores-and-services/flow-cytometry

Core provides analytical flow cytometry services and live cell sorting under enhanced Biosafety Level 2 conditions. Instruments available include six analyzers ranging from 4-30 color acquisition and three sorters using 1-,2-,4-way, and plate sorting between 6-18 colors. Provides experimental and panel design consultation. Provides continued education in seminar format and one-on-one sessions with user.

Proper citation: Tulane University TNBRC Flow Cytometry Core Facility (RRID:SCR_024611) Copy   

•   Source: SciCrunch Registry

https://www.huck.psu.edu/core-facilities/fermentation-facility

Biotechnology pilot plant capable of research and pilot scale production of microbial cells, recombinant proteins, and other microbial products over wide range of controlled conditions. Facility provides equipment and expertise to university affiliated and independent government and industry researchers interested in fermentation and related technologies, including cell separation and disruption, biomolecule production and purification, and process monitoring.

Proper citation: Pennsylvania State University Huck Institutes CSL Behring Fermentation Core Facility (RRID:SCR_024459) Copy   

•   Source: SciCrunch Registry

https://tnprc.tulane.edu/confocal-microscopy-and-molecular-pathology-core

Core provides research support and training with molecular pathology skills, confocal microscopy, image analysis, and multicolor immunohistochemistry and in-situ hybridization techniques for internal and affiliate scientists. Services include assistance with experimental design, antibody selection, molecular probe selection, fixation and staining protocols, operating fluorescent and confocal microscopes, acquiring and storing imaging data, interpretation of results, and generation of publication-quality images. Image analysis services include assistance with capturing images for evaluation and with use of various image analysis software.

Proper citation: Tulane University TNBRC Confocal Microscopy and Molecular Pathology Core Facility (RRID:SCR_024613) Copy   

•   Source: SciCrunch Registry

https://tnprc.tulane.edu/pathogen-detection-and-quantification-core

THIS RESOURCE IS NO LONGER AVAILABLE. SAME SERVICES ARE AVAILABLE IN Molecular Virology and Sequencing Core. Documented on January 28,2025. Core provides services for maintaining Specific Pathogen Free status in macaque breeding colonies. Services include antibody detection in serum or plasma by Luminex-based assays and /or ELISA for SPF-agents like SIV, SRV, STLV, B virus, SFV. CMV, RRV, SVV, SV40, and LCV, and non-SPF infectious agents like measles, Burkholderia pseudomallei, Tripanosoma cruzi, Mycobacterium tuberculosis, and SARS-CoV-2. Offers services of cytokines quantification, and molecular assays for detection of SRV, CMV, SFV, and RRV.Performs nucleic acid purification from blood and tissue samples as well as qPRC for SIV viral load in plasma, cells, or tissue.

Proper citation: Tulane University TNPRC Pathogen Detection and Quantification Core Facility (RRID:SCR_024614) Copy   

•   Source: SciCrunch Registry

https://github.com/singerlabgt/BrainWAVE

Code to program and run flicker stimulation on BrainWAVE stimulator device. This brain oscillation stimulating software can be adapted across subjects and integrated into variety of experimental designs like electrophysiology, neuroimaging, EEG, MRI. Flexible method for noninvasive stimulation of brain rhythms across species. Used to measure effects of rhythmic brain activity on behavior.

Proper citation: BrainWAVE (RRID:SCR_024396) Copy   

•   Source: SciCrunch Registry

https://github.com/jkbonfield/htscodecs/

Software repository implements the custom CRAM codecs used for "EXTERNAL" block types.Custom compression for CRAM custom algorithm written to compress the BAM file format for DNA sequencing data.

Proper citation: Htscodecs (RRID:SCR_024034) Copy   

•   Source: SciCrunch Registry