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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.clcbio.com/products/clc-genomics-workbench/
Commercially available software for visualization and analysis of next generation sequencing data. Used for viewing, exploring, and sharing of NGS analysis results. Complete toolkit for genomics, transcriptomics, epigenomics, and metagenomics in one program.
Proper citation: CLC Genomics Workbench (RRID:SCR_011853) Copy
http://www.scienceexchange.com/facilities/caresbio-laboratory
CaresBio Laboratory (CBL) is a contract research organization, serving as a translational link with the one stop service approach to close the gaps between basic and clinical sciences for biomedical science community. We are serving academic laboratories, CROs, biotechnology and pharmaceutical companies and research organizations by providing high quality and cost effective pre-clinical and clinical research services. If you are doing biomarker and or drug discovery and development; therapeutics and translational research along with the applications of genomics and proteomics study; data validation and analysis; histopathology, immunohistochemistry, pathology or other immunostaining, imaging; histomorphometry, image analysis; small animal imaging; screening, efficacy and toxicity testing of your candidate compounds. We also provide biostatistics analysis of pre-clinical and or clinical data, data base developments or any subcategories of these fields. We do assay developments and provide customized assays to match your needs.
Proper citation: CaresBio Laboratory (RRID:SCR_012393) Copy
With remarkable advances in genomic technologies, the National Cancer Institute established the Core Genotyping Facility (CGF) to investigate the contribution of germline genetic variation to cancer susceptibility and outcomes. Working in concert with epidemiologists, biostatisticians and basic research scientists in the intramural research program, the CGF has developed the capacity to conduct genome-wide association studies and candidate gene approaches to identify the heritable determinants of various forms of cancer. In order to ensure the accuracy and timely completion of all CGF provided operations, the following Information Systems were developed. While the investigator does not have direct access to these systems, their availability to CGF staff members greatly aids in their querying and reporting capabilities. In turn this provides benefit to the investigator by providing the most up to date reporting possible. The Core Genotyping Facility (CGF) offers a wide variety of sample preparation and genotyping operations. All samples received must meet minimum requirements and are taken through the Sample Handling pipeline prior to completing any genotyping. The Sample Handling pipeline includes DNA quantification and genetic fingerprinting. Also offered are Whole Genome Amplification (WGA) assays, to get the most yield out of low quantity DNA samples. Theirr genotyping products cover a wide-range of assay sizes. The CGF operates the Illumina BeadLab system which supports Illumina assay technologies including the whole genome genotyping Infinium assays, custom GoldenGate OPA assays, and Custom Infinium (iSelect) assays. In addition, the CGF offers Affymetrix GeneChip arrays and uniplex TaqMan genotyping. Sponsors: CGF is supported by the SAIC-Frederick. :Keywords: Genomic, Technology, Cancer, Genotyping, Germline, Genetic, Epidemiologist, Biostatistician, Research, Gene, Assay, Genotype, Pipeline, Genome, DNA, :
Proper citation: Core Genotyping Facility (RRID:SCR_008438) Copy
http://www.baylor.edu/psychologyneuroscience/
Goal of Department is creation and dissemination of knowledge in psychological sciences, fostering environment conducive to creative scholarship and learning among both students and faculty, and application of knowledge to betterment and service of society. Offers Bachelor of Science and Bachelor of Arts degree in Psychology as well as few undergraduate degree programs in Neuroscience.
Proper citation: Baylor University Department of Psychology and Neuroscience (RRID:SCR_007224) Copy
Collection of dissemination and exchange recorded biomedical signals and open-source software for analyzing them. Provides facilities for cooperative analysis of data and evaluation of proposed new algorithm. Providies free electronic access to PhysioBank data and PhysioToolkit software. Offers service and training via on-line tutorials to assist users at entry and more advanced levels. In cooperation with annual Computing in Cardiology conference, PhysioNet hosts series of challenges, in which researchers and students address unsolved problems of clinical or basic scientific interest using data and software provided by PhysioNet. All data included in PhysioBank, and all software included in PhysioToolkit, are carefully reviewed. Researchers are further invited to contribute data and software for review and possible inclusion in PhysioBank and PhysioToolkit. Please review guidelines before submitting material.
Proper citation: PhysioNet (RRID:SCR_007345) Copy
http://www.daimi.au.dk/%7Emailund/SNPFile/
Software library and API for manipulating large SNP datasets with associated meta-data, such as marker names, marker locations, individuals'' phenotypes, etc. in an I/O efficient binary file format. In its core, SNPFile assumes very little about the metadata associated with markers and individuals, but leaves this up to application program protocols. (entry from Genetic Analysis Software)
Proper citation: SNPFILE (RRID:SCR_009402) Copy
http://www.radnet.ucla.edu/sections/DINR/index.htm
Annotated images of human brain derived from CT, MRI, angiography and post-mortem sections and drawings. Brain vasculature: arteries, arterioles, veins. Pathological specimens. Quizzes and general information on brain structures and clinical syndromes. Extensive collection of images, many from pathological conditions.
Proper citation: Salamons Neuroanatomy and Neurovasculature Web-Atlas Resource (RRID:SCR_007343) Copy
https://www.marshallhealth.org/locations/marshall-neuroscience-huntington
Purpose of Neuroscience department is to treat diseases of central and peripheral nervous systems and their supporting elements including skull and spine, as single system, utilizing expertise of variety of specialists, closely interacting with one another professionally with regard primarily for care of individual patient and their particular situation.Neuroscience department is committed to teaching and research in the fields of neurology and neruosurgery. Residents and medical students are welcome to rotate with us, or to join us for any of our scheduled lectures and conferences.
Proper citation: Marshall University Medical Center Marshall Neuroscience (RRID:SCR_007460) Copy
The Department of Pharmacology is among the oldest and largest in North America, with its official foundations in 1887, at the same time that the Faculty of Medicine was re-established in the University of Toronto. We offer training in pharmacology and toxicology to both undergraduate and graduate students who may subsequently go on to exciting research, regulatory and administrative careers in academic, industrial and healthcare provision settings.Current areas of research investigation in the Department include Receptor Pharmacology, Signal Transduction Pathways, Neuropharmacology, Drug Addiction Studies, Drug Metabolism and Pharmacokinetics, Pharmacogenetics, Cardiovascular Pharmacology, Clinical Pharmacology, Behavioural Pharmacology, Immunopharmacology, Endocrine Pharmacology and Molecular Toxicology. Our research laboratories are located not only in the core Department situated in the Medical Sciences Building on the downtown St. George campus, but also within a number of nearby university Departments, Faculties, university-affiliated research institutes and teaching hospitals. This strategic positioning also enables a wealth of potential opportunities for interdisciplinary collaboration with internationally recognized investigators within one of the largest and densest existing concentrations of biomedical research expertise in North America.
Proper citation: University of Toronto Toronto Ontario Canada Pharmacology and Toxicology (RRID:SCR_007536) Copy
http://www.plexdb.org/index.php
PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens. PLEXdb is a genotype to phenotype, hypothesis building information warehouse, leveraging highly parallel expression data with seamless portals to related genetic, physical, and pathway data. The integrated tools of PLEXdb allow investigators to use commonalities in plant biology for a comparative approach to functional genomics through use of large-scale expression profiling data sets.
Proper citation: PLEXdb - Plant Expression Database (RRID:SCR_006963) Copy
http://hdbase.org/cgi-bin/welcome.cgi
A community website for Huntington''s Disease (HD) research that currently contains Y2H and Mass spectrometry protein-protein interaction data centered around the HD protein (huntingtin) and information on therapeutic studies in mouse. Also available are raw Human and Mouse Affymetrix Microarray data. The protein interaction data is from several sources, including interactions curated from the literature by ISB staff, experimentally determined interactions produced by Bob Hughes and colleagues at Prolexys (currently password protected), and interactions reported in a recent publication by Goehler et al from Eric Wanker''s lab. Content areas that may be covered by the site include the following: * Therapeutic studies in mouse, primarily drug screens. * HD mouse models with a focus on timelines of disease progression. * Antibodies used in HD research. * Microarray gene expression studies. * Genes and proteins relevant to HD research. This includes HD itself, the growing list of proteins thought to interact directly or indirectly with huntingtin (Htt), and other genes and proteins implicated in the disease process. * Molecular pathways thought to be involved in the disease process. * Timelines of disease for Mouse models
Proper citation: HDBase (RRID:SCR_007132) Copy
A tool for automatic segmentation of 3D biological datasets, with emphasis on 3D electron microscopy. It works best for 3D blob shaped objects like mitochondria, lysosomes, etc. The project is written in Python and uses the pythonxy platform (which includes scipy and ITK image processing tools).
Proper citation: Cytoseg (RRID:SCR_009553) Copy
http://www.uams.edu/pharmtox/default.asp
THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 25,2022. Department of Pharmacology and Toxicology is the professional home to 18 faculty, 11 research faculty, 22 graduate students and 3 postdoctoral fellows. They offer graduate training leading to the Ph.D. degree in Pharmacology or Interdisciplinary Toxicology. Their faculty also participate in the Interdisciplinary Biological Sciences (IBS) training programs. Trainees receive a broad-based education to prepare for a career in translational research. An emphasis on therapeutic development, identification of drug targets and mechanisms of organ injury prepare our trainees for a career in drug discovery and medical toxicology. All of our students currently receive a $24,000 yearly stipend and we pay tuition! Their 'magnet areas' for research include behavioral and drug abuse pharmacology, drug discovery and antibody therapeutics, mechanisms and therapies of organ toxicology and neurodegenerative diseases, and CNS and vascular ion channels. Extramural research funding obtained by the faculty has increased to more than 5 million annually, and the Department ranks in the top quarter of all medical school pharmacology departments in the country in NIH funding.
Proper citation: University of Arkansas for Medical Sciences Department of Pharmacology and Toxicology (RRID:SCR_007496) Copy
http://www.scienceexchange.com/facilities/michigan-state-university
An Portal, Core facility
Proper citation: Michigan State University Labs and Facilities (RRID:SCR_012252) Copy
http://info.med.yale.edu/pharm/
The Department of Pharmacology at Yale University offers integrated and interdisciplinary opportunities for graduate study under the newly organized Program in Biological and Biomedical Sciences (BBS). Students entering the BBS program can take courses, participate in laboratory rotations, and perform thesis research with any of the more than 200 faculty members in the biological sciences at Yale located at the closely situated School of Medicine and Science Hill ends of campus. The faculty and students of the BBS program are organized into moderately-sized, interest-based Tracks to ensure individualized attention and maximize scientific interactions. Prospective students apply to the Track that best matches their interests, although there is complete freedom to work with faculty members in any Track or to switch Tracks after arrival at Yale.
Proper citation: Yale School of Medicine Pharmacology (RRID:SCR_010594) Copy
http://www.digitalfishlibrary.org/index.php
A database of 3D magnetic resonance (MRI) images of fish accessible to scientists, educators and the general public via the web. The Marine Vertebrate Collection at the Scripps Institution of Oceanography provides the majority of the DFL specimens.
Proper citation: Digital Fish Library (RRID:SCR_008338) Copy
A collection of content, including podcasts and blogs, to advance life science research, connecting people and ideas in the life sciences. Mendelspod creates a space for probing conversations and deep insight into the topics and trends which shape the industry''s future and therefore our future as a species. The podcasts are engaging, thoughtful thirty minute shows twice a week on highly relevant topics to those working around the life sciences. Their format enables them to go in depth with scientists who are leaders in their field, or CEOs of high growth companies to explore trends and the latest technologies. At Mendelspod, they offer a front row seat to the revolution going on in biology, putting a human face on some complicated, highly technical topics. Here you can tune in to hear Steve Burrill give his ''state of the industry'' overview, or listen to George Church talk about art and science, or find out how the latest developments in NGS are helping in the war on cancer. The blogs cover the latest trends and products, and can be entertaining. Guest bloggers featured and welcomed.
Proper citation: Mendelspod (RRID:SCR_009027) Copy
https://www.med.unc.edu/psych/research/niral/download/software-pages/fibertracking
A cross-platform system for exploring diffusion tensor images and to reconstruct fiber tracts between two regions of interest, intended for tdoctors, medical technicians or medical researchers. The Fiber-Tracking tool allows the user to load data from MRIs or similar images (like a basic 3D image viewer), load DTI datasets (7 diffusion- weighted images), calculate the fractional anisotropy (FA) and the mean diffusivity (MD) images, and also load ROIs to reconstruct fibers.
Proper citation: Fiber Tracking / DTI Checker (RRID:SCR_007364) Copy
http://rarediseases.info.nih.gov/GARD/Default.aspx
Genetic and Rare Diseases Information Center (GARD) is a collaborative effort of two agencies of the National Institutes of Health, The Office of Rare Diseases Research (ORDR) and the National Human Genome Research Institute (NHGRI) to help people find useful information about genetic conditions and rare diseases. GARD provides timely access to experienced information specialists who can furnish current and accurate information about genetic and rare diseases. So far, GARD has responded to 27,635 inquiries on about 7,147 rare and genetic diseases. Requests come not only from patients and their families, but also from physicians, nurses and other health-care professionals. GARD also has proved useful to genetic counselors, occupational and physical therapists, social workers, and teachers who work with people with a genetic or rare disease. Even scientists who are studying a genetic or rare disease and who need information for their research have contacted GARD, as have people who are taking part in a clinical study. Community leaders looking to help people find resources for those with genetic or rare diseases and advocacy groups who want up-to-date disease information for their members have contacted GARD. And members of the media who are writing stories about genetic or rare diseases have found the information GARD has on hand useful, accurate and complete. GARD has information on: :- What is known about a genetic or rare disease. :- What research studies are being conducted. :- What genetic testing and genetic services are available. :- Which advocacy groups to contact for a specific genetic or rare disease. :- What has been written recently about a genetic or rare disease in medical journals. GARD information specialists get their information from: :- NIH resources. :- Medical textbooks. :- Journal articles. :- Web sites. :- Advocacy groups, and their literature and services. :- Medical databases.
Proper citation: Genetic and Rare Diseases Information Center (RRID:SCR_008695) Copy
http://www.pharm.stonybrook.edu/
The Department ofPharmacological Sciencesat Stony Brook offers a collegial atmosphere with one of the highest ratios of postdoctoral to predoctoral researchers of any Pharmacology Department in the country. Students in Molecular and Cellular Pharmacology work alongside students from several other graduate programs at Stony Brook, including Molecular and Cellular Biology, Neurobiology, Chemistry, Genetics, Microbiology, Structural Biology, and Physiology and Biophysics. Several students in Molecular and Cellular Pharmacology have been trainees in the NIH-funded MSTP (Medical Scientist Training Program).
Proper citation: SUNY Stony Brook, Pharmacological Sciences (RRID:SCR_007480) Copy
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