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http://ccr.coriell.org/Sections/Collections/CSCB/Default.aspx

Biospecimen repository that provides scientists with the opportunity to bank their pluripotent stem cell lines and develops in-house induced pluripotent stem cell (iPSC) lines for distribution. They have developed core capabilities to maintain, characterize, bank, and distribute important stem cell resources. The SCB performs extensive identification and characterization testing for all submitted human induced pluripotent stem cell (iPSC) and mouse embryonic stem cell (mES) lines. The identification and quality control measures include karyotype analysis, microsatellite analysis for parental cell line identity matching, sterility testing, and assessment of viability after cryopreservation. Pluripotency characterizations performed by SCB vary depending upon the distributing repository. * NIGMS iPSCs: Surface antigen expression, Embryoid body formation, Pluritest Gene Expression assay * NINDS iPSCs: Surface antigen expression, Embryoid body formation * NIA mES: Surface antigen expression, Embryoid body formation, Transgene induction Each characterized human iPSC line and mES line released for distribution is provided with a Certificate of Analysis, which includes information regarding characterization and quality of the line, images and links to original publications. The human iPSCs distributed by Coriell are strictly for research purposes and cannot be used in human subjects. All terms described in the Material Transfer Agreement (NIGMS and NINDS Repositories) or Assurance Form (NIA Repository) for the stem cell line must be agreed to prior to using stem cell lines from Coriell.

Proper citation: Coriell Institute Stem Cell Biobank (RRID:SCR_008745) Copy   

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http://ctn.uwaterloo.ca/index.html

The Centre for Theoretical Neuroscience (CTN) was recently established at the University of Waterloo. The Centre is a growing research initiative of the University. The Centre consists of several labs focused on various areas of theoretical neuroscience (aka computational neuroscience). At present, the Centre consists of faculty members from Applied Mathematics, Biology, Psychology, Engineering, Philosophy, Statistics, Computer Science, and their students. The Centre has established a unique Graduate Program in theoretical neuroscience and hosts a regular academic colloquium series. The Centre also hosts the annual public Waterloo Brain Day lectures. The Centre is currently expanding, running searches for additional core faculty. The distinguished faculty of the Centre include two Canada Research Chairs and a fellow of the Royal Society of Canada. In addition, the Centre has a number of student researchers, both graduate and undergraduate, and hosts postdocs and visiting researchers. The Centre also hosts a graduate program for students wishing to obtain an officially recognized specialization in theoretical neuroscience. Faculty at the Centre pursue work on purely theoretical questions regarding the foundational principles guiding the function of neural systems, as well as constructing detailed neurobiological models of specific brain areas.

Proper citation: Center for Theoretical Neuroscience; University of Waterloo (RRID:SCR_008747) Copy   

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http://www.neurophys.biomedicale.univ-paris5.fr/~graham/surf-hippo.html

The Surf-Hippo neuron simulator is used to investigate morphologically and biophysically detailed compartmental models of single neurons and networks of neurons. Surf-Hippo allows ready construction of cells and networks using built-in functions and various anatomical file formats (Neurolucida, NTS and others). Surf-Hippo is a public domain package, written in Lisp, and runs under Unix and Linux.

Proper citation: The Surf-Hippo Neuron Simulation System (RRID:SCR_007257) Copy   

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http://www.cytopathology-foundation.org/

Cytopathology Foundation is a non-profit organization dedicated to the health care for the advancement of art and science of Cytopathology dealing with study of cells for proper disease management especially cancer. Cytopathology is a well established diagnostic sub-specialty of pathology. Instead of using surgically removed tissue to arrive at a diagnosis it attempts to identify diagnostic and prognostic information from dispersed cells obtained by non-invasive or minimally invasive techniques. An example, and its greatest success story thus far, is the role it has played in the battle with cervical cancer. The introduction of the Pap smear has contributed immensely to the early diagnosis and significantly decreased mortality of cervical cancer. Activities of the foundation 1. Support the mission statement in general. 2. Support the editorial and publication expenses of CytoJournal. 3. Future activities may include publication and marketing of cytopathology related literature, to generate funds. 4. Support any other scholarly activities in Cytopathology and related areas.

Proper citation: Cytopathology Foundation (RRID:SCR_008467) Copy   

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http://www.neuroethics.ubc.ca/

It is an interdisciplinary research group dedicated to tackling the ethical, legal, policy and social implications of frontier technological developments in the neurosciences. Our objective is to align innovations in the brain sciences with societal, cultural and individual human values through high impact research, education and outreach. The Core''s major research projects are focused on high impact, high visibility areas including the use of drugs and devices for neuroenhancement, ethics in neurodegenerative disease and regenerative medicine research, international and cross-cultural challenges in brain research, neuroimaging in the private sector, and the ethics of personalized medicine, among others. Members of the Core also lead initiatives aside from their research projects. Sponsors: This Core is supported by the University of Brititsh Columbia.

Proper citation: UBC National Core for Neuroethics (RRID:SCR_008063) Copy   

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http://tronolab.epfl.ch

Retroelements constitute important evolutionary forces for the genome of higher organisms, yet their uncontrolled spread, whether from endogenous loci or within the context of viral infections, can cause diseases such as cancer, hepatitis and AIDS. Correspondingly, a variety of host-encoded activities limit this process, belonging to a line of defense commonly called intrinsic or innate immunity, which notably contributes to taming endogenous retroelements and to restricting the cross-species transmission of retroviruses. Our work aims at characterizing the relationship between retroelements and their hosts, which has recently led us to become more generally interested in epigenetic mechanisms regulating the expression of mammalian genomes.

Proper citation: Tronolab (RRID:SCR_008580) Copy   

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http://bnmc.caltech.edu/

The Beckman Institute BNMC brings together researchers from many disciplines at Caltech to address problems in the mechanistic modeling of coupled genomic, intercellular and intracellular processes. It represents an attempt to encourage closer interaction and collaboration between groups in Biology, Control and Dynamical Systems, and the Center for Advanced Computing Research. The focus of BNMC is biochemical phenomena occurring within and between cells, in particular the mechanistic modeling of molecular networks of all kinds (e.g., transcriptional, regulatory, metabolic, signal transduction, mechanical, etc.) with and without spatial variation and intercellular communication. BNMC is formed as a coordinated effort aimed at (1) applying existing capabilities to collaboratively solve biological modeling problems that arise in answering scientific questions in Caltech laboratories, (2) exploring a diversity of novel approaches in order to achieve fundamental advances necessary to address the classes of modeling problems biologists want to solve, and (3) organizing projects to better share human experience as well as common infrastructure to avoid duplication and maximize solution interoperability.

Proper citation: Caltech, The Beckman Institute: The Biological Network Modeling Center (RRID:SCR_008060) Copy   

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http://www.autopack.org/

A specialized version of autoPack designed to pack biological components together. The current version is optimized to pack molecules into cells with biologically relevant interactions to populate massive cell models with atomic or near-atomic details. Components of the algorithm pack transmembrane proteins and lipids into bilayers, globular molecules into compartments defined by the bilayers (or as exteriors), and fibrous components like microtubules, actin, and DNA.

Proper citation: Cellpack (RRID:SCR_006831) Copy   

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http://www.sabc.murdoch.edu.au/

The SABC is the collaborative university Centre for R&D in agricultural and veterinary biotechnology in Western Australia. It provides platform technologies and world class equipment and facilities for R&D in agricultural biotechnology to researchers from universities, state government and industry. More than 20 research groups and companies rent space and use the SABC facilities. It is based at Murdoch University in Perth. Our Vision To be an eminent, internationally recognized centre for research and development in agriculture and veterinary biotechnology Our Mission To provide state-of-the-art facilities and equipment enabling multi disciplinary research in biotechnology which under pins the agricultural and veterinary industry, for the benefit of the community. This will be achieved by being recognised as the centre for agricultural biotechnology in WA providing national and international research links and collaborations fostering establishment of national centres in leading edge technologies Characteristics of the SABC * The SABC is a multi-user centre with a research spend of about $9 million pa * There is a critical mass of more than 225 researchers * The SABC combines university, state government and industry researchers in one cost-effective centre * The SABC operates as a ''Research Hotel'' in which different groups rent common laboratory space and access to platform technologies * The SABC supports incubation and co-location of new ag biotech companies in WA * The SABC promotes collaborative research, undertakes contract research, and provides many local, national and international linkages * SABC researchers are members of eight agricultural Cooperative Centres (CRCs) Research Focus The research focus is on molecular activities that involve or promote primary production of commercial livestock, crop plants or microbes, or their subsequent processing for added value. The SABC also supports research in biomedical sciences, and environmental biotechnology. Deliverables and Outcomes SABC researchers have an outstanding track record of outputs and outcomes. These include the provision of co-located, state-of-the art, well run platform technologies for all WA researchers plant breeding support leading to improved crop varieties (molecular markers, yield, resistance to diseases and pests, better quality, variety ID, diagnostics), improved productivity and health of livestock, and biomedical diagnostics. Facilities and platform technologies The SABC provides the most comprehensive set of equipment and facilities for biotechnology R&D in WA, with full facilities for: cell and molecular biology, robotics, high throughput agricultural genetic analyses and diagnostics, structural, comparative and functional genomics, microarray technologies, proteomics and mass spectroscopy and bioinformatics support via the (CBBC). Training and Mentoring The SABC plays a major role in advanced training in ag biotech. There are about 100 Honours and PhD students in the research complement. The SABC also runs a series of hands on short courses in molecular biology, gene mapping, diagnostics, proteomics and bioinformatics. In 2005 new postgraduate certificate and diploma courses on Application of Molecular Technologies was established at Murdoch University, run by internationally qualified SABC researchers. These provide advanced education at the Postgraduate Certificate, Diploma and MSc levels, for local and international participants. click here for details The SABC runs the following hands-on training workshops: * Introduction to Molecular Biology * Molecular Mapping Techniques in Diagnostic Biotechnology * High Throughput Genetic Analysis * Introduction to Proteomics * Advanced Proteomics * Bioinformatics (with the CBBC) Competitive Advantages The SABC: * combines crop, veterinary and biomedical research in biotechnology in one centre * is multidisciplinary and inclusive * provides enabling facilities, platform technologies and common laboratories * is highly cost effective Researcher Groups Using the SABC * Division of Health Sciences (Murdoch)/Veterinary Sciences * Division of Science and Engineering (Murdoch)/Biological Sciences and Biotechnology * UWA (Natural Resources and Agriculture, Biochemistry) * Curtin University (Molecular Biotechnology, Horticulture) * Edith Cowan University (Human Genetics) * WA Dept of Agriculture (animal, plant, microbial) * Fisheries * Perth Zoo * Plant Biotechnology Research Group * Australian Centre for Necrotrophic Fungal Pathogens (ACNFP) * Rumen Biotechnology * Centre for High Throughput Agricultural Genetic Analysis (CHAGA) * Veterinary Virology, Parasitology, Microbiology * Saturn Biotech Pty Ltd * Grain Biotech Australia Pty Ltd * Proteomics International * Lighthouse Laboratories Pty Ltd * ID PLUS Pty Ltd * Royal Perth Hospital * Fremantle Hospital * Australian Neuromuscular Research Institute (ANRI) Partnering Opportunities The SABC can provide full facilities for contract R&D, start up companies or co-location of existing companies in agricultural, veterinary and biomedical sciences via its incubation program. Contact the Director for further information. Partnering Needs Investors interested in commercializing outputs of SABC researchers.

Proper citation: Western Australian State Agricultural Biotechnology Centre (RRID:SCR_008577) Copy   

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http://www.mrli.ppdi.com

PPD is a leading global contract research organization (CRO), celebrating 25 years of providing drug discovery, development and lifecycle management services. Our clients and partners include pharmaceutical, biotechnology, medical device, academic and government organizations. With offices in 41 countries and more than 10,500 professionals worldwide, PPD applies innovative technologies, therapeutic expertise and a commitment to quality to help clients and partners accelerate the delivery of safe and effective therapeutics and maximize the returns on their R&D investments. Discovery Services: BioDuro, A PPD Company A drug discovery services company focused on integrated drug discovery programs Nonclinical development Preclinical services partners. Compound Partnering PPD''s compound partnering business is now Furiex Pharmaceuticals, Inc., an independent, publicly traded company. Collaboration with Merck Our strategic collaboration with Merck enabled us to acquire its vaccines and biologics infrastructure, broaden our therapeutic expertise and expand our existing relationship. Alliance with WHISCON We have expanded our post-approval safety expertise and risk management through an alliance with World Health Information Science Consultants. Partnership with PUL To meet growing client demand in Southeast Asia, we partnered with Peking Union Lawke Biomedical Development Limited (PUL) to establish our central lab services in China. Our e-Newsletter is your source for what is happening at PPD and in the CRO industry.

Proper citation: Clinical Trial Solutions with PPD (RRID:SCR_008457) Copy   

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https://corporate.qiagen.com/newsroom/press-releases/press-release-details/2009/QIAGEN-to-Acquire-SABiosciences/default.aspx

SABiosciences, as part of QIAGEN, offers nucleic acid (DNA, RNA, miRNA) and protein isolation, preparation and purification services, as well as assay,array, sequencing, NGS and biomarker services and lab essentials.Offers PCR services, assays, array systems, and expression vectors. Acquired by QIAGEN in 2009.

Proper citation: SABiosciences (RRID:SCR_008578) Copy   

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http://casr.adelaide.edu.au/rotater/

The Centre for Automotive Safety Research at the University of Adelaide, is internationally recognised as a leading research organisation in its field. The Centre conducts high quality independent research that enables rational decision making, leading to a reduction in the human and economic losses from road crashes. The Centre is focused on: * Conducting multidisciplinary research to understand how road crashes and the resulting injuries are caused * Proposing and evaluating ways to prevent crashes and injuries * Providing independent professional advice on road safety matters to government and non-government organisations in Australia and overseas The Centre began life in 1973 as the Road Accident Research Unit (RARU) with the planning and undertaking of an in-depth study of road accidents in the Adelaide metropolitan area. From 1981 through 1998, the Unit''s work was supported by a grant from the National Health And Medical Research Council. During that grant period RARU''s research program was concentrated in two areas: the study of brain injury mechanisms in fatally injured road users and the epidemiology of drink driving and alcohol related crashes. Notably, an investigation of the influence of vehicle speed in fatal pedestrian accidents led on to case control studies of the relationship between a driver''s travelling speed and risk of involvement in a casualty crash in both urban and rural areas. RARU''s analysis of the occurrence of brain injury in road crashes called into question the then prevailing paradigm of brain injury mechanisms. This prompted the development of an experimental study of axonal injury that, in turn, led to the Japan Automobile Research Institute initiating a formal collaborative research agreement with RARU, and now with CASR, in the area of crash injury biomechanics. Also a part of our legacy is that over 40 years ago the Centre''s previous Director, Professor Jack McLean, co-authored the first paper in the world to show that car design played a major role in pedestrian protection, revealing that pedestrians are run under, not over, by the striking car.

Proper citation: Centre for Automotive Safety Research (RRID:SCR_008573) Copy   

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http://www.bnf.org/bnf/

The BNF aims to provide prescribers, pharmacists and other healthcare professionals with sound up-to-date information about the use of medicines. The BNF provides ready access to key information on the selection, prescribing, dispensing and administration of medicines. Medicines that are generally prescribed in the UK are covered and those considered less suitable for prescribing are clearly identified.

Proper citation: British National Formulary (RRID:SCR_008176) Copy   

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http://www.rickhanseninstitute.org

Organization that facilitates spinal cord injury research and care. By accelerating the translation of discoveries and best practices into improved treatments, it aims to improve the lives of people living with SCI.

Proper citation: Rick Hansen Institute (RRID:SCR_008570) Copy   

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http://www.mayo.edu/research/centers-programs/alzheimers-disease-research-center

A clinical research department that specializes in the study of Alzheimer's disease. The Mayo Clinic Alzheimer's Disease Research Center conducts many types of research studies related to dementia, as well as normal or successful aging. The purpose of the center is to provide care for dementia patients and promote research and education on Alzheimer's Disease and related dementias.

Proper citation: Mayo Alzheimer's Disease Research Center (RRID:SCR_008727) Copy   

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http://www.nitrc.org/projects/namicdtifiber/

Project hosting binary packaged distributions, scripts, example datasets, and corresponding results of analysis using their UNC/Utah NAMIC DTI Fiber Analysis Framework. This project can be seens as a master project encompassing several current NITRC projects into a coherent set. Their workflow utilizes tools already available on NITRC including: * DTIPrep * DTIAtlasBuilder * FiberViewerLight * DTIAtlasFiberAnalyzer * FADTTS

Proper citation: UNC/Utah NAMIC DTI Fiber Analysis Framework (RRID:SCR_009615) Copy   

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http://www.nhpreagents.org

Center that facilitates the optimal use of nonhuman primate models in biomedical research by identifying, developing, characterizing and producing reagents for monitoring or modulating immune responses. They distribute non-human primate-specific antibodies for in vitro diagnostics, as well as develop and produce primate recombinant antibodies for in vivo cell depletion or modulating immune responses.

Proper citation: Nonhuman Primate Reagent Resource (RRID:SCR_012986) Copy   

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http://www.scienceexchange.com/facilities/artforscience

ArtforScience helps faculty and scientists communicate their research data for grants, talks, publications, posters, or websites. The illustrations and schematics of biological data have appeared in many of the widely-used textbooks and scientific journals. Our work has been featured on the covers of Cell, Science, and Nature, among others.

Proper citation: ArtforScience (RRID:SCR_012506) Copy   

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http://www.mitre.org/

The MITRE Corporation is a not-for-profit organization chartered to work in the public interest. As a national resource, we apply our expertise in systems engineering, information technology, operational concepts, and enterprise modernization to address our sponsors'' critical needs. MITRE manages Federally Funded Research and Development Centers (FFRDCs): one for the Department of Defense (known as the DoD Command, Control, Communications and Intelligence FFRDC), one for the Federal Aviation Administration (the Center for Advanced Aviation System Development), one for the Internal Revenue Service and U.S. Department of Veterans Affairs (the Center for Enterprise Modernization), and one for the Department of Homeland Security (the Homeland Security Systems Engineering and Development Institute). We believe that each FFRDC benefits from being part of an independent, not-for-profit company managing multiple FFRDCs. MITRE also has its own independent research and development program that explores new technologies and new uses of technologies to solve our sponsors'' problems in the near-term and in the future. MITRE has 7,000 scientists, engineers and support specialists65 percent of whom have Masters or Ph.D. degrees. Staff members work on hundreds of different projects across the company, demanding a high level of technical, operational, and domain knowledge. The MITRE Corporation has two principal locations: Bedford, Massachusetts, and McLean, Virginia. MITRE also has additional sites across the country and around the world.

Proper citation: MITRE (RRID:SCR_010690) Copy   

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http://www.tcgls.com/

Leading contract research and manufacturing services company in the area of drug discovery and development.

Proper citation: TCG Life Sciences (RRID:SCR_010571) Copy   

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