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https://www.crr.columbia.edu/raraf

RARAF is dedicated to providing user-friendly radiation sources and bio-labs for research in biology, radiation biology, and radiation physics.

Proper citation: Columbia University Radiological Research Accelerator Core Facility (RRID:SCR_012639) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/transgenic-mouse-shared-resource-columbia

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Core facility that specializes in the generation and analysis of genetically modified mice, including transgenic and knockout animals, is an essential technology for biomedical research. Our services include: Production of transgenic mice by pronuclear DNA microinjection and embryo transfer. Production of chimeric mice by blastocyst injection of genetically modified ES cells and embryo transfer, which is part of the procedure of producing knockout or knockin mice. Gene targeting, which involves the electroporation of a targeting vector into pluripotent mouse embryonic stem (ES) cells and the selection of gene-targeted clones. Education of investigators and advice on vector and experimental design for experiments using transgenic and knockout mice. Bioimaging: The Animal Imaging Service provides investigators the opportunity for non-invasive detection, localization, and longitudinal monitoring of primary and metastatic cancer cells in vivo, in allograft, zenograft, transgenic and knock-out mouse models. The IVIS Spectrum (Caliper Life Sciences, Hopkinton MA) uses optical imaging technology to detect bioluminescent and fluorescent reporters across the blue to near infrared wavelength region. DNA samples and ES cell lines are injected in the order in which the signed service request forms are received. Currently, the average time from receipt of the service request to injection is approximately 2 weeks. For ES Cell electroporation and expansion, success in gene targeting cannot be guaranteed due to inherent variability in the frequency of targeting different loci, and the possibility of mistakes or mutations in the targeting vector.

Proper citation: Columbia Transgenic Mouse Shared Resource (RRID:SCR_012640) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/electron-microscopy-core-laboratory-upenn

The Electron Microscopy Resource Laboratory (EMRL ) at Penn is a research facility dedicated to ultrastructure analysis of biological samples by electron microscopy (EM). We offer high quality EM imaging services at low cost. With a team of experienced professional staff and state-of-the-art sample preparation and imaging equipment, the EMRL offers users a full spectrum of both transmission EM and scanning EM services.

Proper citation: Penn Electron Microscopy Core Laboratory (RRID:SCR_012642) Copy   

•   Source: SciCrunch Registry

https://pcrlab.vetmed.ucdavis.edu/

Real-time PCR Research and Diagnostics Core Facility accepts research projects from both academic and private sector. The Core Facility can accommodate projects involving laser microdissection, RNA and DNA extractions through semi-automated nucleic acid extractions systems, cDNA synthesis and complete Real-time PCR analysis using a laser 7900 HTA FAST platform.

Proper citation: University of California at Davis Real Time PCR Research and Diagnostics Core Facility (RRID:SCR_012641) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/protein-structure-core-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein Structure Core Facility operates in the department of Biochemistry and Molecular Biology, on the UNMC campus. The facility performs protein sequencing, amino acid analysis and peptide mapping on a fee-for-service basis. It is located on the first floor of the Durham Research Center

Proper citation: UNMC Protein Structure Core Facility (RRID:SCR_012609) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/molecular-biotechnology/

Core offers services in areas of peptide synthesis, peptide modification, purification and quality analysis, N-terminal protein sequencing by Edman degradation, and biomolecular interaction analysis and equilibrium and kinetic measurements.

Proper citation: Cleveland Clinic Molecular Biotechnology Core Facility (RRID:SCR_012600) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/babraham-commercialisation-services-ltd

Babraham Institute Enterprise Limited (BIE) is the wholly-owned trading arm of the Babraham Institute. The Babraham Institute undertakes innovative life-sciences research to discover the molecular mechanisms that underlie normal cellular processes and functions, with the aim of improving lifelong wellbeing and healthy ageing.

Proper citation: Babraham Institute Enterprise Limited (RRID:SCR_012566) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/characterisation

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 22, 2016. Network of laboratories which provides leading-edge research capability and supports excellence in science. The capability provided by ANFF enables users to process hard materials (metals, composites and ceramics) and soft materials (polymers and polymer-biological materials) and transform these into structures that have various applications.

Proper citation: ANFF Characterisation (RRID:SCR_012687) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/clinical-pharmacology-analytical-services-cpas

The Clinical Pharmacology Analytical Services laboratory (CPAS) resides in the Department of Experimental and Clinical Pharmacology (ECP) in the University of Minnesota College of Pharmacy. CPAS offers quantification services of drug concentrations in biological samples. The CLIA-certified lab and its team of researchers and clinicians the resources to measure drug concentrations in blood and tissue samples of human and animal origin, including animals as patients and animals serving as research models. The lab which opened in October 2003 uses state-of-the-art equipment to facilitate analysis of drugs, xenobiotics, endogenous compounds and biological samples. Capabilities of the core lab include LC-MS/MS, LC-MS, GC-MS, HPLC-UV and HPLC-FLD. Additional, UV and fluorescent plate readers and liquid scintillation counters are available for conducting ELISA, RIA and other assays in a 96-well plate format. Because of its flexible structure, customers can purchase only the services they need, including assay consultation, assay development and validation, conduct of assays and application. Lab services are made available to researchers from within and outside the University of Minnesota community.

Proper citation: University of Minnesota Clinical Pharmacology Analytical Services (RRID:SCR_012603) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/william-harvey-research-limited

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. A Contract research organization offering pre-clinical drug evaluation service specialising in models of cardiovascular and inflammatory diseases such as myocardial ischemia, haemorrhagic shock, endotoxaemia also inflammatory bowel disease (IBD), neutrophil migration, pulmonary fibrosis, systemic lupus erthematosus (SLE), adjuvant arthritis, collagen II arthritis, EAE and many more.

Proper citation: William Harvey Research Limited (RRID:SCR_012574) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/immunodetection-and-imaging

Delivering high quality immunohistochemical and immunofluorescent staining on cells and tissue sections, specialising in multi immunoflourescent colocalisation staining technologies. Equipped with three Vision Biosystems Bond staining robots Mike offers high throughput or custom antibody optimisation services. Time consuming multi colocalisation including same species primaries, are automated saving time and money. A large range of imaging platforms including three confocals, widefield, stereology, image analysis, digital photograpy and PALM laser capture microscopy are available. A full range of secondary antibodies and detection systems are available for purchase in ul quantities. There are currently 1900 antibodies recorded on our database.

Proper citation: University of Edinburgh Immunodetection and Imaging (RRID:SCR_012573) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/biomolecular-interaction-centre

The Biomolecular Interaction Centre (BIC) is a multi-disciplinary centre dedicated to the study of molecular interactions critical to biological function. Understanding biomolecular interactions is central to a range of fundamental sciences, new treatments for disease, and a wide range of highly functional products. The Institute includes University of Canterbury researchers from the Colleges of Science and Engineering, as well as Education and Arts and partners with several New Zealand CRIs and Universities. The Centre was founded in 2007 after being awarded funding from the Innovation and Development Fund from the Tertiary Education Commission (TEC). The primary investment of $1.85 million was used to purchase of a suite of state-of-the-art equipment that was supplied by Bio-Rad Laboratories. BIC has recently received a multi-million dollar investment from the University of Canterbury to become one of two new premier research institutes on campus. BIC researchers seek to understand the molecular interactions vital to biology and harness them in a wide range of applications. BIC has a number of Principal, Partner, Associate and Affliated Investigators, together with Post Doctoral Fellows, Postgraduate students and technicians from the University of Canterbury, as well as, other national and international institutions. Many these investigators directly support the research themes of the Centre while others have related research projects that benefit from BIC support.

Proper citation: University of Canterbury Biomolecular Interaction Centre (RRID:SCR_012618) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/vivalis

Vivalis contract manufacturing services offers a full suite of services that include GMP cell banking, GMP antibody production, and GMP virus production. Our manufacturing facility has been approved by the French Medicines Agency for GMP production up to Phase II clinical trials. A rigorous Quality Management System (QMS) maintains GMP compliance and further ensures adherence to these quality requirements.

Proper citation: Vivalis (RRID:SCR_012578) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/pathology-core-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2,2024. Core Pathology is a self funding, CPA accredited department and therefore is a fee-for-service facility providing Histopathology services to members of Queen Mary University and other academic institutes, as well as providing a diagnostic service to the private sector. Our remit is to advise, support or carry out work for research groups.

Proper citation: QMUL BICM Pathology Core Facility (RRID:SCR_012587) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/small-animal-imaging-core-umass

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 23,2024. UMMS Small Animal Imaging Core was established in early 2008 to serve the UMMS and extramural research community by providing state-of-the-art small animal imaging.

Proper citation: UMass Medical School Small Animal Imaging Core (RRID:SCR_012620) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/laboratory-of-medical-zoology

We offer expanded tick testing services for a variety of tick-borne pathogens, including Babesia, Anaplasma, Rickettsia, Bartonella, and others.

Proper citation: UMass Amherst Laboratory of Medical Zoology (RRID:SCR_012586) Copy   

•   Source: SciCrunch Registry

https://proteomics.ucdavis.edu/

Core provides LC-MS/MS analysis including Protein ID, Proteomics Profiling, Targeted Proteomics and Post Translational Modification analysis. Analytical proteomic services are provided with emphasis on label free quantitative proteomic profiling, analysis of macromolecular complexes, post-translational modification of their constituents and standard protein identification from complex protein mixtures.

Proper citation: University of California at Davis Genome Center Proteomics Core Facility (RRID:SCR_012666) Copy   

•   Source: SciCrunch Registry

https://marine-geosciences.earth.miami.edu/research-themes/paleoclimatology-and-geochemistry/stable-isotope-laboratory/index.html

Laboratory facility has two Isoprime Isotope Ratio mass spectrometers. One capable of measuring oxygen and hydrogen isotope ratios of water and the other capable of measuring carbon and nitrogen isotope ratios of organic matter.

Proper citation: University of Miami Stable Isotope Laboratory Core Facillity (RRID:SCR_012668) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/the-analyte-center-bcm

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Analyte Center provides analytical services to the research community within Baylor College of Medicine and to investigators at other institutions. We provide access to state-of-the-art gas chromatography/mass spectroscopy, tandem mass spectroscopy, and high pressure liquid chromatography for the purpose of quantitative analysis of small organic molecules. In addition to a broad spectrum of routinely offered services we can also provide specialty services on demand provided our instrumentation will provide the sensitivity and specificity required for the investigator.

Proper citation: BCM Analyte Center (RRID:SCR_012669) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/infectious-disease-resource-core-arizona

IDRC aims to improve the detection and prevention of infectious diseases, by developing new diagnostic laboratory methods for use in evidence-based research and clinical practice

Proper citation: UA Infectious Disease Resource Core (RRID:SCR_012671) Copy   

•   Source: SciCrunch Registry